GWAS730359_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS730359_H (alcohol drinking, high density lipoprotein cholesterol measurement QTL GWAS730359 (human)) Homo sapiens

Symbol: GWAS730359_H
Name: alcohol drinking, high density lipoprotein cholesterol measurement QTL GWAS730359 (human)
RGD ID: 407081383
Trait: alcohol drinking, high density lipoprotein cholesterol measurement
Measurement Type: blood high density lipoprotein cholesterol level   (CMO:0000052)    
LOD Score: Not Available
P Value: 3.0E-13
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381544,492,177 - 44,492,178RGD_MAPPER_PIPELINEGRCh38
GRCh371544,784,375 - 44,784,376RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS730359_HHumanblood high density lipoprotein cholesterol level  IAGPrs28487964405850206Based on the EFO term IDGWAS_CATALOGPMID:30698716

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS730359_HHumanalcohol drinking  IAGPrs28487964405850206 GWAS_CATALOGPMID:30698716
GWAS730359_HHumanhigh density lipoprotein cholesterol measurement  IAGPrs28487964405850206 GWAS_CATALOGPMID:30698716
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1605073CTDSPL2CTD small phosphatase like 2154442762944529038Human

Position Markers

Peak: (rs28487964)
Human AssemblyChrPosition (strand)Source
GRCh381544,492,177 - 44,492,178RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407096067GWAS745043_Htriglyceride measurement QTL GWAS745043 (human)0.000003triglyceride measurementblood triglyceride level (CMO:0000118)154449217744492178Human
407081024GWAS730000_Hhigh density lipoprotein cholesterol measurement QTL GWAS730000 (human)0.0000003high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407070695GWAS719671_Halcohol drinking, high density lipoprotein cholesterol measurement QTL GWAS719671 (human)1e-17alcohol drinking, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
407081383GWAS730359_Halcohol drinking, high density lipoprotein cholesterol measurement QTL GWAS730359 (human)3e-13alcohol drinking, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
407115170GWAS764146_Htriglyceride measurement, alcohol consumption measurement QTL GWAS764146 (human)2e-11triglyceride measurement, alcohol consumption measurementethanol drink intake rate (CMO:0001407)154449217744492178Human
407114019GWAS762995_Htriglyceride measurement, alcohol consumption measurement QTL GWAS762995 (human)5e-12triglyceride measurement, alcohol consumption measurementethanol drink intake rate (CMO:0001407)154449217744492178Human
407308480GWAS957456_Hglycoprotein measurement QTL GWAS957456 (human)5e-08glycoprotein measurement154449217744492178Human
407279182GWAS928158_Hhigh density lipoprotein cholesterol measurement QTL GWAS928158 (human)0.000009high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
407279052GWAS928028_Hhigh density lipoprotein cholesterol measurement QTL GWAS928028 (human)5e-11high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
407073901GWAS722877_Htriglyceride measurement, alcohol drinking QTL GWAS722877 (human)2e-10triglyceride measurementblood triglyceride level (CMO:0000118)154449217744492178Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407095089GWAS744065_Halcohol consumption measurement, high density lipoprotein cholesterol measurement QTL GWAS744065 (human)6e-16alcohol consumption measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
407114608GWAS763584_Halcohol consumption measurement, high density lipoprotein cholesterol measurement QTL GWAS763584 (human)1e-16alcohol consumption measurement, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407275987GWAS924963_Hhigh density lipoprotein cholesterol measurement QTL GWAS924963 (human)8e-09high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)154449217744492178Human
407084661GWAS733637_Htriglyceride measurement QTL GWAS733637 (human)0.0000002triglyceride measurementblood triglyceride level (CMO:0000118)154449217744492178Human
407073466GWAS722442_Htriglyceride measurement, alcohol drinking QTL GWAS722442 (human)7e-12triglyceride measurement, alcohol drinkingblood triglyceride level (CMO:0000118)154449217744492178Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407277656GWAS926632_Htriglyceride measurement QTL GWAS926632 (human)4e-11triglyceride measurementblood triglyceride level (CMO:0000118)154449217744492178Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS719671_H GCST008084 HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 1E-17 17 rs28487964 N/A alcohol drinking (EFO:0004329)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS722442_H GCST008083 Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 7E-12 11.155 rs28487964 N/A triglyceride measurement (EFO:0004530)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS722877_H GCST008083 Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 2E-10 9.699 rs28487964 N/A triglyceride measurement (EFO:0004530)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS730000_H GCST008070 HDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals A NR 3E-7 6.523 rs28487964 0.02939 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS730359_H GCST008084 HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers A NR 3E-13 12.523 rs28487964 N/A alcohol drinking (EFO:0004329)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS733637_H GCST008076 Triglyceride levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals A NR 2E-7 6.699 rs28487964 0.072 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS744065_H GCST008075 HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 6E-16 15.222 rs28487964 N/A alcohol consumption measurement (EFO:0007878)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS745043_H GCST008076 Triglyceride levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals A NR 0.000003 5.523 rs28487964 0.077 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS762995_H GCST008074 Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 5E-12 11.302 rs28487964 N/A triglyceride measurement (EFO:0004530)
alcohol consumption measurement (EFO:0007878)
 PMID:30698716
GWAS763584_H GCST008075 HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 1E-16 16 rs28487964 N/A alcohol consumption measurement (EFO:0007878)
high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS764146_H GCST008074 Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers A NR 2E-11 10.699 rs28487964 N/A triglyceride measurement (EFO:0004530)
alcohol consumption measurement (EFO:0007878)
 PMID:30698716
GWAS924963_H GCST008085 HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals A NR 8E-9 8.097 rs28487964 0.028 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS926632_H GCST008087 Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals A NR 4E-11 10.398 rs28487964 0.068 triglyceride measurement (EFO:0004530)
 PMID:30698716
None Available GCST008087 Triglyceride levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals A NR 2E-10 9.699 rs28487964 0.071 triglyceride measurement (EFO:0004530)
 PMID:30698716
GWAS928028_H GCST008085 HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals A NR 5E-11 10.302 rs28487964 0.03 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS928158_H GCST008085 HDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals A NR 0.000009 5.046 rs28487964 0.056 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:30698716
GWAS957456_H GCST90092821 Glycoprotein acetyls levels 115,082 European ancestry individuals T 0.971887 5E-8 7.302 rs28487964 0.0703632 glycoprotein measurement (EFO:0004555)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST008084 GWAS Catalog

RGD Curation Notes
Note Type Note Reference