GWAS717272_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS717272_H (esterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS717272 (human)) Homo sapiens

Symbol: GWAS717272_H
Name: esterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS717272 (human)
RGD ID: 407068296
Trait: esterified cholesterol measurement, low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 8.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38472,882,942 - 72,882,943RGD_MAPPER_PIPELINEGRCh38
GRCh37473,748,659 - 73,748,660RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS717272_HHumanblood low density lipoprotein cholesterol level  IAGPrs546498715405850206Based on the EFO term IDGWAS_CATALOGPMID:29084231

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS717272_HHumanesterified cholesterol measurement  IAGPrs546498715405850206 GWAS_CATALOGPMID:29084231
GWAS717272_HHumanlow density lipoprotein cholesterol measurement  IAGPrs546498715405850206 GWAS_CATALOGPMID:29084231
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs546498715)
Human AssemblyChrPosition (strand)Source
GRCh38472,882,942 - 72,882,943RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407068545GWAS717521_Hfree cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS717521 (human)2e-08free cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407068298GWAS717274_Hlow density lipoprotein cholesterol measurement QTL GWAS717274 (human)8e-09esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407332717GWAS981693_Hthioproline measurement QTL GWAS981693 (human)7e-18thioproline measurement47288294272882943Human
407068296GWAS717272_Hesterified cholesterol measurement, low density lipoprotein cholesterol measurement QTL GWAS717272 (human)8e-10esterified cholesterol measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407068808GWAS717784_Hlow density lipoprotein cholesterol measurement QTL GWAS717784 (human)5e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407313065GWAS962041_HX-22771 measurement QTL GWAS962041 (human)2e-13X-22771 measurement47288294272882943Human
407069075GWAS718051_Hlow density lipoprotein cholesterol measurement QTL GWAS718051 (human)1e-21low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407068049GWAS717025_Hlow density lipoprotein cholesterol measurement QTL GWAS717025 (human)4e-10low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407068535GWAS717511_Hlow density lipoprotein cholesterol measurement QTL GWAS717511 (human)4e-11low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human
407089847GWAS738823_Hesterified cholesterol measurement QTL GWAS738823 (human)7e-09esterified cholesterol measurement47288294272882943Human
407079286GWAS728262_Htotal cholesterol measurement QTL GWAS728262 (human)3e-16total cholesterol measurementblood total cholesterol level (CMO:0000051)47288294272882943Human
407089850GWAS738826_Hfree cholesterol measurement QTL GWAS738826 (human)3e-08free cholesterol measurementblood cholesterol level (CMO:0002280)47288294272882943Human
407068056GWAS717032_Hlow density lipoprotein cholesterol measurement QTL GWAS717032 (human)1e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)47288294272882943Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS717025_H GCST005486 Medium LDL particle concentration 8,372 Finnish ancestry males ? NR 4E-10 9.398 rs546498715 0.5 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717032_H GCST005488 Total cholesterol levels in medium LDL 8,372 Finnish ancestry males ? NR 1E-9 9 rs546498715 0.5 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717272_H GCST005489 Cholesterol ester levels in medium LDL 8,372 Finnish ancestry males ? NR 8E-10 9.097 rs546498715 0.5 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717274_H GCST005483 Total cholesterol levels in large LDL 8,372 Finnish ancestry males ? NR 8E-9 8.097 rs546498715 0.5 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
None Available GCST005484 Cholesterol ester levels in large LDL 8,372 Finnish ancestry males ? NR 8E-9 8.097 rs546498715 0.5 esterified cholesterol measurement (EFO:0008589)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717511_H GCST005491 Total cholesterol levels in small LDL 8,372 Finnish ancestry males ? NR 4E-11 10.398 rs546498715 0.6 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717521_H GCST005485 Free cholesterol levels in large LDL 8,372 Finnish ancestry males ? NR 2E-8 7.699 rs546498715 0.5 free cholesterol measurement (EFO:0008591)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS717784_H GCST005481 Large LDL particle concentration 8,372 Finnish ancestry males ? NR 5E-9 8.302 rs546498715 0.5 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS718051_H GCST005490 Small LDL particle concentration 8,372 Finnish ancestry males ? NR 1E-21 21 rs546498715 0.591 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:29084231
GWAS728262_H GCST005448 Serum total cholesterol levels 8,372 Finnish ancestry males ? NR 3E-16 15.523 rs546498715 0.505 total cholesterol measurement (EFO:0004574)
 PMID:29084231
GWAS738823_H GCST005444 Esterified cholesterol levels 8,372 Finnish ancestry males ? NR 7E-9 8.155 rs546498715 0.5 esterified cholesterol measurement (EFO:0008589)
 PMID:29084231
GWAS738826_H GCST005445 Free cholesterol levels 8,372 Finnish ancestry males ? NR 3E-8 7.523 rs546498715 0.5 free cholesterol measurement (EFO:0008591)
 PMID:29084231
GWAS962041_H GCST90140556 X-22771 levels 6,136 Finnish ancestry individuals A NR 2E-13 12.699 rs546498715 0.51 X-22771 measurement (EFO:0800844)
 PMID:35347128
GWAS981693_H GCST90140825 Thioproline levels 6,136 Finnish ancestry individuals A NR 7E-18 17.155 rs546498715 0.6 thioproline measurement (EFO:0801012)
 PMID:35347128
Database Acc Id Source(s)
GWAS Catalog GCST005489 GWAS Catalog

RGD Curation Notes
Note Type Note Reference