GWAS716562_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS716562_H (heel bone mineral density QTL GWAS716562 (human)) Homo sapiens

Symbol: GWAS716562_H
Name: heel bone mineral density QTL GWAS716562 (human)
RGD ID: 407067586
Trait: heel bone mineral density
Measurement Type: bone mineral density   (CMO:0001226)    
LOD Score: Not Available
P Value: 2.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38168,137,448 - 68,137,449RGD_MAPPER_PIPELINEGRCh38
GRCh37168,603,131 - 68,603,132RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS716562_HHumanbone mineral density  IAGPrs4397637405850206Based on the EFO term IDGWAS_CATALOGPMID:28869591

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS716562_HHumanheel bone mineral density  IAGPrs4397637405850206 GWAS_CATALOGPMID:28869591
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
6769446GNG12-AS1GNG12, DIRAS3 and WLS antisense RNA 116783228868202987Human
1605334WLSWnt ligand secretion mediator16809845968232546Human

Position Markers

Peak: (rs4397637)
Human AssemblyChrPosition (strand)Source
GRCh38168,137,448 - 68,137,449RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407067586GWAS716562_Hheel bone mineral density QTL GWAS716562 (human)2e-11heel bone mineral densitybone mineral density (CMO:0001226)16813744868137449Human
2314561GLUCO47_HGlucose level QTL 47 (human)1.1Glucose level14477336070773360Human
1578602LDLPS21_HLow density lipoprotein particle size QTL 21 (human)2.050.00037LDL particle size15253110578531105Human
1578620LDLPS20_HLow density lipoprotein particle size QTL 21 (human)2.040.00046LDL particle size15253110578531105Human
407089862GWAS738838_Hheel bone mineral density QTL GWAS738838 (human)7e-10heel bone mineral densitybone mineral density (CMO:0001226)16813744868137449Human
1578594LDLPS19_HLow density lipoprotein particle size QTL 19 (human)2.560.00009LDL particle size15253110578531105Human
407013084GWAS662060_Hheel bone mineral density QTL GWAS662060 (human)5e-43heel bone mineral densitybone mineral density (CMO:0001226)16813744868137449Human
407072428GWAS721404_Hheel bone mineral density QTL GWAS721404 (human)6e-20heel bone mineral densitybone mineral density (CMO:0001226)16813744868137449Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS662060_H GCST006433 Heel bone mineral density 394,929 European ancestry individuals ? NR 5E-43 42.302 rs4397637 0.035059 heel bone mineral density (EFO:0009270)
 PMID:30048462
GWAS716562_H GCST006288 Heel bone mineral density 76,067 European ancestry women, 66,420 European ancestry men G 0.812718 2E-11 10.699 rs4397637 0.0383038 heel bone mineral density (EFO:0009270)
 PMID:28869591
GWAS721404_H GCST006288 Heel bone mineral density 76,067 European ancestry women, 66,420 European ancestry men G 0.813715 6E-20 19.222 rs4397637 0.0388858 heel bone mineral density (EFO:0009270)
 PMID:28869591
GWAS738838_H GCST006288 Heel bone mineral density 76,067 European ancestry women, 66,420 European ancestry men G 0.814856 7E-10 9.155 rs4397637 0.0384775 heel bone mineral density (EFO:0009270)
 PMID:28869591
Database Acc Id Source(s)
GWAS Catalog GCST006288 GWAS Catalog

RGD Curation Notes
Note Type Note Reference