GWAS712375_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS712375_H (monocyte percentage of leukocytes QTL GWAS712375 (human)) Homo sapiens

Symbol: GWAS712375_H
Name: monocyte percentage of leukocytes QTL GWAS712375 (human)
RGD ID: 407063399
Trait: monocyte percentage of leukocytes
Measurement Type: blood monocyte count to total leukocyte count ratio   (CMO:0000374)    
LOD Score: Not Available
P Value: 1.0E-12
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381541,956,317 - 41,956,318RGD_MAPPER_PIPELINEGRCh38
GRCh371542,248,515 - 42,248,516RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS712375_HHumanblood monocyte count to total leukocyte count ratio  IAGPrs147477118405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS712375_HHumanmonocyte percentage of leukocytes  IAGPrs147477118405850206 GWAS_CATALOGPMID:32888494
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
734140EHD4EH domain containing 4154189593341972557Human
151675985LOC124903477uncharacterized LOC124903477154194310741956665Human

Position Markers

Peak: (rs147477118)
Human AssemblyChrPosition (strand)Source
GRCh381541,956,317 - 41,956,318RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407202436GWAS851412_Hmonocyte count QTL GWAS851412 (human)2e-40monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)154195631741956318Human
407335589GWAS984565_Hmonocyte count QTL GWAS984565 (human)1e-52monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)154195631741956318Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407063399GWAS712375_Hmonocyte percentage of leukocytes QTL GWAS712375 (human)1e-12monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)154195631741956318Human
407120424GWAS769400_Hleukocyte count QTL GWAS769400 (human)8e-28leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)154195631741956318Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407108078GWAS757054_Hplatelet crit QTL GWAS757054 (human)1e-11platelet critplateletcrit (CMO:0001349)154195631741956318Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS712375_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals C 0.119582 1E-12 12 rs147477118 0.024657995 monocyte percentage of leukocytes (EFO:0007989)
 PMID:32888494
GWAS757054_H GCST90002400 Plateletcrit 408,112 British individuals C 0.119431 1E-11 11 rs147477118 0.023865493 platelet crit (EFO:0007985)
 PMID:32888494
GWAS769400_H GCST90002407 White blood cell count 408,112 British individuals C 0.119561 8E-28 27.097 rs147477118 0.03883769 leukocyte count (EFO:0004308)
 PMID:32888494
GWAS851412_H GCST90002393 Monocyte count 408,112 British individuals C 0.119567 2E-40 39.699 rs147477118 0.04721891 monocyte count (EFO:0005091)
 PMID:32888494
GWAS984565_H GCST90018967 Monocyte count 349,856 European ancestry individuals, 95,119 East Asian ancestry individuals C NR 1E-52 52 rs147477118 0.0479 monocyte count (EFO:0005091)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90002394 GWAS Catalog

RGD Curation Notes
Note Type Note Reference