GWAS705431_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS705431_H (eosinophil count QTL GWAS705431 (human)) Homo sapiens

Symbol: GWAS705431_H
Name: eosinophil count QTL GWAS705431 (human)
RGD ID: 407056455
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count   (CMO:0000033)    
LOD Score: Not Available
P Value: 2.0E-20
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh385177,365,490 - 177,365,491RGD_MAPPER_PIPELINEGRCh38
GRCh375176,792,491 - 176,792,492RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS705431_HHumanblood eosinophil count  IAGPrs6556313405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS705431_HHumaneosinophil quantity  IAGPrs6556313405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS705431_HHumaneosinophil count  IAGPrs6556313405850206 GWAS_CATALOGPMID:32888493
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733515RGS14regulator of G protein signaling 145177357924177372596Human

Position Markers

Peak: (rs6556313)
Human AssemblyChrPosition (strand)Source
GRCh385177,365,490 - 177,365,491RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407056929GWAS705905_Heosinophil count QTL GWAS705905 (human)1e-16eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)5177365490177365491Human
406944339GWAS593315_Heosinophil percentage of leukocytes QTL GWAS593315 (human)1e-11eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)5177365490177365491Human
2289409BW320_HBody weight QTL 320 (human)3.50.0002Body weightlean mass5160925164181538259Human
407056455GWAS705431_Heosinophil count QTL GWAS705431 (human)2e-20eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)5177365490177365491Human
407214626GWAS863602_Hcalcium measurement QTL GWAS863602 (human)1e-12calcium measurementblood calcium level (CMO:0000502)5177365490177365491Human
407101208GWAS750184_Heosinophil count QTL GWAS750184 (human)1e-21eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)5177365490177365491Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS593315_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals G 0.331564 1E-11 11 rs6556313 0.015856218 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS705431_H GCST90002298 Eosinophil counts 474,237 European ancestry individuals G 0.332338 2E-20 19.699 rs6556313 0.019467 eosinophil count (EFO:0004842)
 PMID:32888493
GWAS705905_H GCST90002381 Eosinophil counts 408,112 British individuals G 0.331552 1E-16 16 rs6556313 0.019359725 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS750184_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 1E-21 21 rs6556313 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS863602_H GCST012398 Calcium levels 305,349 European ancestry individuals G 0.3318 1E-12 12 rs6556313 0.001649 calcium measurement (EFO:0004838)
 PMID:33887147
None Available GCST90448623 Phosphate levels 38,000 South Asian ancestry individuals G NR 7E-11 10.155 rs6556313 0.051 phosphate measurement (EFO:0010968)
 PMID:39414775
Database Acc Id Source(s)
GWAS Catalog GCST90002298 GWAS Catalog

RGD Curation Notes
Note Type Note Reference