GWAS683823_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS683823_H (myeloid white cell count QTL GWAS683823 (human)) Homo sapiens

Symbol: GWAS683823_H
Name: myeloid white cell count QTL GWAS683823 (human)
RGD ID: 407034847
Trait: myeloid white cell count
Measurement Type: white blood cell count   (CMO:0000027)    
LOD Score: Not Available
P Value: 4.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh382201,247,748 - 201,247,749RGD_MAPPER_PIPELINEGRCh38
GRCh372202,112,471 - 202,112,472RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS683823_HHumanwhite blood cell count  IAGPrs10931933405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS683823_HHumanmyeloid white cell count  IAGPrs10931933405850206 GWAS_CATALOGPMID:32888493
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
730846CASP8caspase 82201233463201287711Human

Position Markers

Peak: (rs10931933)
Human AssemblyChrPosition (strand)Source
GRCh382201,247,748 - 201,247,749RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293458PRSTS291_HProstate tumor susceptibility QTL 291 (human)0.012Prostate tumor susceptibility2200715236226715236Human
407112405GWAS761381_Hleukocyte count QTL GWAS761381 (human)2e-12leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)2201247748201247749Human
407336326GWAS985302_Hleukocyte count QTL GWAS985302 (human)6e-12leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)2201247748201247749Human
407176582GWAS825558_Hmultiple sclerosis QTL GWAS825558 (human)0.000001multiple sclerosis2201247748201247749Human
1643053BW117_HBody Weight QTL 117 (human)2.40.00044Body weight2200715236226715236Human
407102263GWAS751239_Hleukocyte count QTL GWAS751239 (human)4e-15leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)2201247748201247749Human
407034847GWAS683823_Hmyeloid white cell count QTL GWAS683823 (human)4e-16myeloid white cell countwhite blood cell count (CMO:0000027)2201247748201247749Human
1643254BW125_HBody Weight QTL 125 (human)1.450.005Body weightbody mass index2200715236226715236Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS683823_H GCST90002374 White blood cell count 562,243 European ancestry individuals T 0.605269 4E-16 15.398 rs10931933 0.015422 myeloid white cell count (EFO:0007988)
 PMID:32888493
GWAS751239_H GCST90002407 White blood cell count 408,112 British individuals T 0.608701 4E-15 14.398 rs10931933 0.017830206 leukocyte count (EFO:0004308)
 PMID:32888494
GWAS761381_H GCST007070 White blood cell count approximately 444,000 European ancestry individuals ? NR 2E-12 11.699 rs10931933 N/A leukocyte count (EFO:0004308)
 PMID:30595370
GWAS825558_H GCST009597 Multiple sclerosis 14,802 European and unknown ancestry cases, 26,703 European and unknown ancestry controls G NR 0.000001 6 rs10931933 1.0573 PMID:31604244
GWAS985302_H GCST90018978 White blood cell count 350,470 European ancestry individuals, 154,355 East Asian ancestry individuals T NR 6E-12 11.222 rs10931933 0.0138 leukocyte count (EFO:0004308)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90002374 GWAS Catalog

RGD Curation Notes
Note Type Note Reference