GWAS683579_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS683579_H (cholesterol in small VLDL measurement QTL GWAS683579 (human)) Homo sapiens

Symbol: GWAS683579_H
Name: cholesterol in small VLDL measurement QTL GWAS683579 (human)
RGD ID: 407034603
Trait: cholesterol in small VLDL measurement
LOD Score: Not Available
P Value: 9.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,279,711 - 58,279,712RGD_MAPPER_PIPELINEGRCh38
GRCh371558,571,910 - 58,571,911RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS683579_HHumancholesterol in small VLDL measurement  IAGPrs11854242405850206 GWAS_CATALOGPMID:36764567
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs11854242)
Human AssemblyChrPosition (strand)Source
GRCh381558,279,711 - 58,279,712RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407331719GWAS980695_Hvery low density lipoprotein cholesterol measurement, phospholipid measurement QTL GWAS980695 (human)6e-73very low density lipoprotein cholesterol measurement, phospholipid measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155827971158279712Human
407033121GWAS682097_Hdocosahexaenoic acid measurement QTL GWAS682097 (human)4e-14fatty acid amount (VT:0010046)blood free fatty acids level (CMO:0000117)155827971158279712Human
407029761GWAS678737_Hlinoleic acid measurement QTL GWAS678737 (human)3e-14linoleic acid measurementblood free fatty acids level (CMO:0000117)155827971158279712Human
407037895GWAS686871_Hcholesteryl ester measurement QTL GWAS686871 (human)7e-11blood lipid amount (VT:0003949)155827971158279712Human
407038340GWAS687316_Hremnant cholesterol measurement QTL GWAS687316 (human)3e-10remnant cholesterol measurement155827971158279712Human
407089220GWAS738196_Htriglycerides to total lipids in medium HDL percentage QTL GWAS738196 (human)8e-17triglycerides to total lipids in medium HDL percentage 155827971158279712Human
407034603GWAS683579_Hcholesterol in small VLDL measurement QTL GWAS683579 (human)9e-10cholesterol in small VLDL measurement 155827971158279712Human
407320205GWAS969181_Hlinoleic acid measurement QTL GWAS969181 (human)2e-15linoleic acid measurementblood free fatty acids level (CMO:0000117)155827971158279712Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407119764GWAS768740_Htotal lipids in IDL QTL GWAS768740 (human)3e-16total lipids in IDL155827971158279712Human
407292724GWAS941700_Homega-3 polyunsaturated fatty acid measurement QTL GWAS941700 (human)3e-17omega-6 polyunsaturated fatty acid measurement155827971158279712Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
407040311GWAS689287_Htotal lipids in lipoprotein particles measurement QTL GWAS689287 (human)6e-13total lipids in lipoprotein particles measurement 155827971158279712Human
407117331GWAS766307_Hfree cholesterol in IDL measurement QTL GWAS766307 (human)5e-11free cholesterol in IDL measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)155827971158279712Human
407040731GWAS689707_Hpolyunsaturated fatty acid measurement QTL GWAS689707 (human)6e-19milk polyunsaturated fatty acid amount (VT:0010374)milk polyunsaturated fatty acid measurement (CMO:0000821)155827971158279712Human
407029496GWAS678472_Homega-6 polyunsaturated fatty acid measurement QTL GWAS678472 (human)1e-15sphingomyelin measurement155827971158279712Human
407037433GWAS686409_Htotal cholesterol measurement QTL GWAS686409 (human)1e-09total cholesterol measurementblood total cholesterol level (CMO:0000051)155827971158279712Human
407029534GWAS678510_Homega-3 polyunsaturated fatty acid measurement QTL GWAS678510 (human)1e-14omega-3 polyunsaturated fatty acid measurement155827971158279712Human
407032991GWAS681967_Hfree cholesterol measurement QTL GWAS681967 (human)6e-12free cholesterol measurementblood cholesterol level (CMO:0002280)155827971158279712Human
407104861GWAS753837_Htotal phospholipids in lipoprotein particles measurement QTL GWAS753837 (human)6e-23total phospholipids in lipoprotein particles measurement 155827971158279712Human
407036445GWAS685421_Hcholesteryl ester measurement QTL GWAS685421 (human)2e-11blood lipid amount (VT:0003949)155827971158279712Human
407117627GWAS766603_Hphospholipids in IDL measurement QTL GWAS766603 (human)4e-24phospholipids in IDL measurementblood intermediate density lipoprotein phospholipid level (CMO:0001574)155827971158279712Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS678472_H GCST90269542 Omega-6 fatty acids levels (UKB data field 23445) 88,268 European ancestry individuals T 0.27504 1E-15 15 rs11854242 0.0416175 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:36764567
GWAS678510_H GCST90269541 Omega-3 fatty acids levels (UKB data field 23444) 88,268 European ancestry individuals T 0.27504 1E-14 14 rs11854242 0.0396492 omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
 PMID:36764567
GWAS678737_H GCST90269546 Linoleic acid levels (UKB data field 23449) 88,268 European ancestry individuals T 0.27504 3E-14 13.523 rs11854242 0.0397368 linoleic acid measurement (EFO:0006807)
 PMID:36764567
GWAS681967_H GCST90269516 Total free cholesterol levels (UKB data field 23419) 88,329 European ancestry individuals T 0.274994 6E-12 11.222 rs11854242 0.0359492 free cholesterol measurement (EFO:0008591)
 PMID:36764567
GWAS682097_H GCST90269547 Docosahexaenoic acid levels (UKB data field 23450) 88,268 European ancestry individuals T 0.27504 4E-14 13.398 rs11854242 0.0383509 docosahexaenoic acid measurement (EFO:0007761)
 PMID:36764567
GWAS683579_H GCST90269609 Cholesterol in small VLDL (UKB data field 23512) 88,329 European ancestry individuals T 0.274994 9E-10 9.046 rs11854242 0.0326986 cholesterol in small VLDL measurement (EFO:0022228)
 PMID:36764567
GWAS685421_H GCST90269610 Cholesteryl esters in small VLDL (UKB data field 23513) 88,329 European ancestry individuals T 0.274994 2E-11 10.699 rs11854242 0.0359601 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS686409_H GCST90269497 Total cholesterol levels (UKB data field 23400) 88,329 European ancestry individuals T 0.274994 1E-9 9 rs11854242 0.0315318 total cholesterol measurement (EFO:0004574)
 PMID:36764567
GWAS686871_H GCST90269513 Cholesteryl esters in VLDL (UKB data field 23416) 88,329 European ancestry individuals T 0.274994 7E-11 10.155 rs11854242 0.0347661 cholesteryl ester measurement (EFO:0010351)
 PMID:36764567
GWAS687316_H GCST90269499 Remnant cholesterol (non-HDL, non-LDL -cholesterol) levels (UKB data field 23402) 88,329 European ancestry individuals T 0.274994 3E-10 9.523 rs11854242 0.0335158 remnant cholesterol measurement (EFO:0010815)
 PMID:36764567
GWAS689287_H GCST90269520 Total lipids in lipoprotein particles (UKB data field 23423) 88,329 European ancestry individuals T 0.274994 6E-13 12.222 rs11854242 0.0377016 total lipids in lipoprotein particles measurement (EFO:0022309)
 PMID:36764567
GWAS689707_H GCST90269543 Polyunsaturated fatty acids levels (UKB data field 23446) 88,268 European ancestry individuals T 0.27504 6E-19 18.222 rs11854242 0.0461006 polyunsaturated fatty acid measurement (EFO:0010733)
 PMID:36764567
GWAS738196_H GCST90269740 Triglycerides to total lipids in medium HDL percentage (UKB data field 23643) 88,329 European ancestry individuals T 0.274994 8E-17 16.097 rs11854242 0.0428877 triglycerides to total lipids in medium HDL percentage (EFO:0022333)
 PMID:36764567
GWAS753837_H GCST90269508 Total phospholipids in lipoprotein particles (UKB data field 23411) 88,329 European ancestry individuals T 0.274994 6E-23 22.222 rs11854242 0.0500937 total phospholipids in lipoprotein particles measurement (EFO:0022315)
 PMID:36764567
None Available GCST90269535 Sphingomyelins levels (UKB data field 23438) 88,268 European ancestry individuals T 0.27504 1E-15 15 rs11854242 0.039905 sphingomyelin measurement (EFO:0010118)
 PMID:36764567
GWAS766307_H GCST90269625 Free cholesterol in IDL (UKB data field 23528) 88,329 European ancestry individuals T 0.274994 5E-11 10.302 rs11854242 0.034006 free cholesterol in IDL measurement (EFO:0022181)
 PMID:36764567
GWAS766603_H GCST90269622 Phospholipids in IDL (UKB data field 23525) 88,329 European ancestry individuals T 0.274994 4E-24 23.398 rs11854242 0.0522466 phospholipids in IDL measurement (EFO:0022164)
 PMID:36764567
GWAS768740_H GCST90269621 Total lipids in IDL (UKB data field 23524) 88,329 European ancestry individuals T 0.274994 3E-16 15.523 rs11854242 0.0422543 total lipids in IDL (EFO:0022161)
 PMID:36764567
GWAS941700_H GCST90133362 Total omega-3 fatty acid levels 114,999 European ancestry individuals C 0.72 3E-17 16.523 rs11854242 0.039 omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
 PMID:35692035
GWAS969181_H GCST90133363 Linoleic acid levels 114,999 European ancestry individuals C 0.72 2E-15 14.699 rs11854242 0.036 linoleic acid measurement (EFO:0006807)
 PMID:35692035
None Available GCST90133364 Total omega-6 fatty acid levels 114,999 European ancestry individuals C 0.72 3E-17 16.523 rs11854242 0.038 omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
 PMID:35692035
GWAS980695_H GCST90093036 Phospholipid levels in very small VLDL 115,082 European ancestry individuals C 0.724926 6E-73 72.222 rs11854242 0.0822344 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipid measurement (EFO:0004639)
 PMID:35213538
Database Acc Id Source(s)
GWAS Catalog GCST90269609 GWAS Catalog

RGD Curation Notes
Note Type Note Reference