GWAS671970_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS671970_H (sex hormone-binding globulin measurement QTL GWAS671970 (human)) Homo sapiens

Symbol: GWAS671970_H
Name: sex hormone-binding globulin measurement QTL GWAS671970 (human)
RGD ID: 407022994
Trait: sex hormone-binding globulin measurement
LOD Score: Not Available
P Value: 6.0E-32
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381949,513,222 - 49,513,223RGD_MAPPER_PIPELINEGRCh38
GRCh371950,016,479 - 50,016,480RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS671970_HHumansex hormone-binding globulin measurement  IAGPrs111981233405850206 GWAS_CATALOGPMID:36653534
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
736100FCGRTFc gamma receptor and transporter194951266149526428Human

Position Markers

Peak: (rs111981233)
Human AssemblyChrPosition (strand)Source
GRCh381949,513,222 - 49,513,223RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407022994GWAS671970_Hsex hormone-binding globulin measurement QTL GWAS671970 (human)6e-32sex hormone-binding globulin measurement194951322249513223Human
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
406993091GWAS642067_Hsex hormone-binding globulin measurement QTL GWAS642067 (human)8e-36sex hormone-binding globulin measurement194951322249513223Human
407313729GWAS962705_Htestosterone measurement QTL GWAS962705 (human)2e-12testosterone measurementserum testosterone level (CMO:0000568)194951322249513223Human
407006757GWAS655733_Hsex hormone-binding globulin measurement QTL GWAS655733 (human)2e-37sex hormone-binding globulin measurement194951322249513223Human
406987413GWAS636389_Hsex hormone-binding globulin measurement QTL GWAS636389 (human)8e-33sex hormone-binding globulin measurement194951322249513223Human
407122431GWAS771407_Hreticulocyte count QTL GWAS771407 (human)4e-10reticulocyte counttotal reticulocyte count (CMO:0003020)194951322249513223Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human
407003133GWAS652109_Hsex hormone-binding globulin measurement QTL GWAS652109 (human)2e-46sex hormone-binding globulin measurement194951322249513223Human
407062892GWAS711868_Hglycoprotein measurement QTL GWAS711868 (human)2e-18glycoprotein measurement194951322249513223Human
407318280GWAS967256_Hsex hormone-binding globulin measurement QTL GWAS967256 (human)5e-12sex hormone-binding globulin measurement194951322249513223Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS636389_H GCST90012109 Sex hormone-binding globulin levels 180,726 European ancestry men G 0.07898400000000005 8E-33 32.097 rs111981233 0.0261638 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS642067_H GCST90012108 Sex hormone-binding globulin levels adjusted for BMI 180,094 European ancestry men G 0.07898400000000005 8E-36 35.097 rs111981233 0.0251937 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS652109_H GCST90012110 Sex hormone-binding globulin levels adjusted for BMI 368,929 European ancestry individuals G 0.07955999999999996 2E-46 45.699 rs111981233 0.0214079 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS655733_H GCST90012111 Sex hormone-binding globulin levels 370,125 European ancestry individuals G 0.07955999999999996 2E-37 36.699 rs111981233 0.0209851 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS671970_H GCST90239821 Sex hormone-binding globulin levels 163,363 British ancestry men ? NR 6E-32 31.222 rs111981233 0.069083 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:36653534
GWAS711868_H GCST90301968 Glycoprotein acetylation 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 113,034 European ancestry individuals T 0.9226 2E-18 17.699 rs111981233 0.0694 glycoprotein measurement (EFO:0004555)
 PMID:38448586
GWAS771407_H GCST90002405 Reticulocyte count 408,112 British individuals G 0.079357 4E-10 9.398 rs111981233 0.02578894 reticulocyte count (EFO:0007986)
 PMID:32888494
GWAS962705_H GCST90027095 Total testosterone levels 148,248 British ancestry men G 0.08 2E-12 11.699 rs111981233 0.22 testosterone measurement (EFO:0004908)
 PMID:34321204
GWAS967256_H GCST90027091 Sex hormone-binding globulin levels 148,248 British ancestry men G 0.08 5E-12 11.302 rs111981233 1.01 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:34321204
Database Acc Id Source(s)
GWAS Catalog GCST90239821 GWAS Catalog

RGD Curation Notes
Note Type Note Reference