GWAS665385_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS665385_H (bone density QTL GWAS665385 (human)) Homo sapiens

Symbol: GWAS665385_H
Name: bone density QTL GWAS665385 (human)
RGD ID: 407016409
Trait: bone mineral mass   (VT:0005007)    
Measurement Type: bone mineral density   (CMO:0001226)    
LOD Score: Not Available
P Value: 1.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38122,375,694 - 22,375,695RGD_MAPPER_PIPELINEGRCh38
GRCh37122,702,187 - 22,702,188RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS665385_HHumanbone mineral density  IAGPrs34553872405850206Based on the EFO term IDGWAS_CATALOGPMID:37500982

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS665385_HHumanbone mineral mass  IAGPrs34553872405850206Based on the EFO term IDGWAS_CATALOGPMID:37500982

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS665385_HHumanbone density  IAGPrs34553872405850206 GWAS_CATALOGPMID:37500982
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Vertebrate Trait

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs34553872)
Human AssemblyChrPosition (strand)Source
GRCh38122,375,694 - 22,375,695RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407149566GWAS798542_Hheel bone mineral density QTL GWAS798542 (human)1e-139heel bone mineral densitybone mineral density (CMO:0001226)12237569422375695Human
407016409GWAS665385_Hbone density QTL GWAS665385 (human)1e-10bone mineral mass (VT:0005007)bone mineral density (CMO:0001226)12237569422375695Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS665385_H GCST90321118 Bone mineral density mean 141,261 European ancestry individuals ? NR 1E-10 10 rs34553872 N/A bone density (EFO:0003923)
 PMID:37500982
GWAS798542_H GCST006979 Heel bone mineral density 426,824 British ancestry individuals A 0.823072 1E-139 139 rs34553872 0.06084 heel bone mineral density (EFO:0009270)
 PMID:30598549
Database Acc Id Source(s)
GWAS Catalog GCST90321118 GWAS Catalog

RGD Curation Notes
Note Type Note Reference