QTL |
GWAS Catalog Study |
Disease Trait |
Study Size |
Risk Allele |
Risk Allele Frequency |
P Value |
P Value MLOG |
Peak Marker |
Reported Odds Ratio or Beta-coefficient |
Ontology Accession |
PubMed |
GWAS552636_H |
GCST007141 |
Low density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
A |
0.933 |
2E-47 |
46.699 |
rs10455872 |
0.136 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:29507422 |
GWAS552637_H |
GCST007141 |
Low density lipoprotein cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
A |
NR |
1E-50 |
50 |
rs10455872 |
0.136 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:29507422 |
GWAS553463_H |
GCST90244653 |
Low density lipoprotein cholesterol levels |
29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals |
? |
NR |
2E-28 |
27.699 |
rs10455872 |
6.742727 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:36220816 |
GWAS567577_H |
GCST002287 |
Coronary artery disease or ischemic stroke |
12,389 Ischemic stroke cases, 22,233 Coronary artery disease cases, ~ 88,766 controls |
? |
NR |
2E-12 |
11.699 |
rs10455872 |
N/A |
stroke (EFO:0000712) coronary artery disease (EFO:0001645)
|
PMID:24262325 |
GWAS567631_H |
GCST002290 |
Coronary artery disease or large artery stroke |
2,167 Large artery stroke cases, 22,233 Coronary artery disease cases, ~ 75,921 controls |
? |
NR |
9E-14 |
13.046 |
rs10455872 |
N/A |
large artery stroke (EFO:0005524) coronary artery disease (EFO:0001645)
|
PMID:24262325 |
GWAS591399_H |
GCST009870 |
Calcific aortic valve stenosis |
5,115 European ancestry cases, 354,072 European ancestry controls |
G |
0.081 |
6E-21 |
20.222 |
rs10455872 |
1.54 |
aortic stenosis (EFO:0000266) aortic valve calcification (EFO:0005239)
|
PMID:32141789 |
GWAS592561_H |
GCST011100 |
Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) |
at least 837,415 European ancestry individuals |
A |
0.9267 |
4E-30 |
29.398 |
rs10455872 |
N/A |
longevity (EFO:0004300) healthspan (EFO:0009762) parental longevity (EFO:0007796)
|
PMID:32678081 |
GWAS592584_H |
GCST009890 |
Parental lifespan |
at least 500,193 European ancestry offspring |
A |
0.92 |
9E-25 |
24.046 |
rs10455872 |
0.7639 |
parental longevity (EFO:0007796)
|
PMID:30642433 |
GWAS602508_H |
GCST003117 |
Myocardial infarction |
27,509 European ancestry cases, 130 African American cases, 278 Hispanic American cases, 10,257 South Asian ancestry cases, 288 Lebanese ancestry cases, 1,687 East Asian ancestry cases, 99,121 European ancestry controls, 2,778 African American controls, 3,337 Hispanic American controls, 12,899 South Asian ancestry controls, 466 Lebanese ancestry controls, 7,709 East Asian ancestry controls |
G |
0.05 |
9E-27 |
26.046 |
rs10455872 |
1.33 |
myocardial infarction (EFO:0000612)
|
PMID:26343387 |
GWAS622142_H |
GCST90271563 |
Calcific aortic valve stenosis |
12,395 European ancestry cases, 287,787 European ancestry controls |
G |
0.07 |
3E-51 |
50.523 |
rs10455872 |
1.42 |
aortic stenosis (EFO:0000266) aortic valve calcification (EFO:0005239)
|
PMID:36802703 |
GWAS622153_H |
GCST90271566 |
Calcific aortic valve stenosis |
12,395 European ancestry cases, 287,787 European ancestry controls, 1,445 black cases, 79,299 black controls, 611 Hispanic cases, 31,458 Hispanic controls |
G |
NR |
3E-49 |
48.523 |
rs10455872 |
1.42 |
aortic stenosis (EFO:0000266) aortic valve calcification (EFO:0005239)
|
PMID:36802703 |
GWAS628138_H |
GCST011365 |
Myocardial infarction |
14,825 European ancestry cases, 44,000 European and unknown ancestry cases, 2,680 cases, 380,970 European ancestry controls, 123,504 European and unknown ancestry controls, 73,242 controls |
G |
0.064671 |
1E-82 |
82 |
rs10455872 |
1.37 |
myocardial infarction (EFO:0000612)
|
PMID:33532862 |
GWAS629064_H |
GCST90002412 |
Low density lipoprotein cholesterol levels |
431,167 European ancestry individuals |
A |
0.920929 |
3E-321 |
320.523 |
rs10455872 |
0.135534 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:32493714 |
GWAS630320_H |
GCST011364 |
Myocardial infarction |
14,825 European ancestry cases, 2,680 cases, 380,970 European ancestry controls, 73,242 controls |
G |
0.074987 |
4E-58 |
57.398 |
rs10455872 |
1.39 |
myocardial infarction (EFO:0000612)
|
PMID:33532862 |
GWAS631855_H |
GCST008037 |
Low density lipoprotein cholesterol levels |
9,720 African American individuals, 17,373 Hispanic/Latino individuals, 2,316 Asian ancestry individuals, 1,900 Native Hawaiian ancestry individuals, 591 Native American ancestry individuals, 321 individuals |
? |
NR |
5E-17 |
16.302 |
rs10455872 |
8.089846 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:31217584 |
GWAS635325_H |
GCST011087 |
Lipoprotein (a) levels |
293,274 White ancestry individuals |
G |
0.076 |
6E-22136 |
22135.222 |
rs10455872 |
1.7 |
lipoprotein A measurement (EFO:0006925)
|
PMID:33115273 |
GWAS640476_H |
GCST008045 |
Total cholesterol levels |
10,137 African American individuals, 17,802 Hispanic/Latino individuals, 2,387 Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals |
? |
NR |
2E-15 |
14.699 |
rs10455872 |
8.734887 |
total cholesterol measurement (EFO:0004574)
|
PMID:31217584 |
GWAS641987_H |
GCST011347 |
Low density lipoprotein cholesterol levels |
76,081 European ancestry individuals, 127,395 Japanese ancestry individuals |
? |
NR |
6E-24 |
23.222 |
rs10455872 |
0.1319 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:33339817 |
GWAS651017_H |
GCST90310232 |
Psycho-cardiometabolic multimorbidity (multivariate analysis) |
562,507 European, South Asian, East Asian, Hispanic or African American individuals |
? |
NR |
5E-15 |
14.302 |
rs10455872 |
0.10118637 |
coronary artery disease (EFO:0001645)
|
PMID:37390107 |
GWAS659538_H |
GCST006612 |
LDL cholesterol |
215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals |
A |
0.9351 |
3E-54 |
53.523 |
rs10455872 |
0.0881 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:30275531 |
GWAS660137_H |
GCST006614 |
Total cholesterol levels |
215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals |
A |
0.9351 |
4E-41 |
40.398 |
rs10455872 |
0.0762 |
total cholesterol measurement (EFO:0004574)
|
PMID:30275531 |
GWAS669620_H |
GCST001726 |
Lipoprotein-associated phospholipase A2 activity change in response to statin therapy |
2,673 European ancestry cases, 2,656 European ancestry controls |
G |
0.05 |
2E-16 |
15.699 |
rs10455872 |
4.8 |
lipoprotein-associated phospholipase A(2) measurement (EFO:0004746)
|
PMID:23118302 |
GWAS672421_H |
GCST90269668 |
Triglycerides in medium HDL (UKB data field 23571) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-26 |
25.699 |
rs10455872 |
0.0915572 |
triglycerides in medium HDL measurement (EFO:0022321)
|
PMID:36764567 |
GWAS672428_H |
GCST90269684 |
Free cholesterol to total lipids in very large VLDL percentage (UKB data field 23587) |
87,620 European ancestry individuals |
G |
0.0795309 |
6E-76 |
75.222 |
rs10455872 |
0.156542 |
free cholesterol to total lipids in very large VLDL percentage (EFO:0022289)
|
PMID:36764567 |
GWAS672653_H |
GCST90269685 |
Triglycerides to total lipids in very large VLDL percentage (UKB data field 23588) |
87,620 European ancestry individuals |
G |
0.0795309 |
7E-126 |
125.155 |
rs10455872 |
0.202842 |
triglycerides to total lipids in very large VLDL percentage (EFO:0022340)
|
PMID:36764567 |
GWAS672961_H |
GCST90269683 |
Cholesteryl esters to total lipids in very large VLDL percentage (UKB data field 23586) |
87,620 European ancestry individuals |
G |
0.0795309 |
9E-172 |
171.046 |
rs10455872 |
0.234734 |
cholesteryl esters to total lipids in very large VLDL percentage (EFO:0022258)
|
PMID:36764567 |
GWAS673046_H |
GCST001425 |
Response to statin therapy |
2,702 European ancestry individuals |
A |
NR |
1E-9 |
9 |
rs10455872 |
0.28 |
response to statin (GO:0036273)
|
PMID:22368281 |
GWAS673186_H |
GCST90269687 |
Cholesterol to total lipids in large VLDL percentage (UKB data field 23590) |
88,321 European ancestry individuals |
G |
0.0797432 |
9E-141 |
140.046 |
rs10455872 |
0.216304 |
cholesterol to total lipids in large VLDL percentage (EFO:0022236)
|
PMID:36764567 |
GWAS673424_H |
GCST90269704 |
Free cholesterol to total lipids in very small VLDL percentage (UKB data field 23607) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-24 |
23.523 |
rs10455872 |
0.0885717 |
free cholesterol to total lipids in very small VLDL percentage (EFO:0022290)
|
PMID:36764567 |
GWAS673450_H |
GCST90269705 |
Triglycerides to total lipids in very small VLDL percentage (UKB data field 23608) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-35 |
34.699 |
rs10455872 |
0.103772 |
triglycerides to total lipids in very small VLDL percentage (EFO:0022341)
|
PMID:36764567 |
GWAS673878_H |
GCST90269686 |
Phospholipids to total lipids in large VLDL percentage (UKB data field 23589) |
88,321 European ancestry individuals |
G |
0.0797432 |
8E-23 |
22.097 |
rs10455872 |
0.0837754 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
GWAS674265_H |
GCST90269725 |
Triglycerides to total lipids in small LDL percentage (UKB data field 23628) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-94 |
93.523 |
rs10455872 |
0.17467 |
triglycerides to total lipids in small LDL percentage (EFO:0022337)
|
PMID:36764567 |
GWAS674413_H |
GCST90269724 |
Free cholesterol to total lipids in small LDL percentage (UKB data field 23627) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-107 |
106.398 |
rs10455872 |
0.186254 |
free cholesterol to total lipids in small LDL percentage (EFO:0022286)
|
PMID:36764567 |
GWAS674757_H |
GCST90269745 |
Triglycerides to total lipids in small HDL percentage (UKB data field 23648) |
88,329 European ancestry individuals |
G |
0.0797473 |
5E-34 |
33.302 |
rs10455872 |
0.101712 |
triglycerides to total lipids in small HDL percentage (EFO:0022336)
|
PMID:36764567 |
GWAS676741_H |
GCST90276156 |
Aortic stenosis |
13,765 European ancestry cases, 640,102 European ancestry controls |
? |
NR |
1E-75 |
75 |
rs10455872 |
1.45 |
aortic stenosis (EFO:0000266)
|
PMID:37038246 |
GWAS678149_H |
GCST90269549 |
Omega-6 fatty acids to total fatty acids percentage (UKB data field 23452) |
88,268 European ancestry individuals |
G |
0.0797288 |
3E-61 |
60.523 |
rs10455872 |
0.138852 |
omega-6 polyunsaturated fatty acid measurement (EFO:0005680)
|
PMID:36764567 |
GWAS679411_H |
GCST90269540 |
Degree of unsaturation (UKB data field 23443) |
88,268 European ancestry individuals |
G |
0.0797288 |
1E-36 |
36 |
rs10455872 |
0.105152 |
degree of unsaturation measurement (EFO:0022261)
|
PMID:36764567 |
GWAS679658_H |
GCST90302111 |
Concentration of small VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
7E-28 |
27.155 |
rs10455872 |
0.0926 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS679674_H |
GCST90269592 |
Concentration of large VLDL particles (UKB data field 23495) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-79 |
79 |
rs10455872 |
0.160008 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:36764567 |
GWAS679728_H |
GCST90269539 |
Total fatty acids levels (UKB data field 23442) |
88,268 European ancestry individuals |
G |
0.0797288 |
6E-51 |
50.222 |
rs10455872 |
0.129634 |
fatty acid measurement (EFO:0005110)
|
PMID:36764567 |
GWAS679974_H |
GCST90302112 |
Phospholipids in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
8E-22 |
21.097 |
rs10455872 |
0.0812 |
phospholipids in VLDL measurement (EFO:0022301)
|
PMID:38448586 |
GWAS681007_H |
GCST90269528 |
Average diameter for VLDL particles (UKB data field 23431) |
88,329 European ancestry individuals |
G |
0.0797473 |
6E-156 |
155.222 |
rs10455872 |
0.218163 |
very low density lipoprotein particle size measurement (EFO:0008594)
|
PMID:36764567 |
GWAS681054_H |
GCST90269591 |
Triglycerides in very large VLDL (UKB data field 23494) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-130 |
129.523 |
rs10455872 |
0.20371 |
triglycerides in very large VLDL measurement (EFO:0022325)
|
PMID:36764567 |
GWAS681364_H |
GCST90269593 |
Total lipids in large VLDL (UKB data field 23496) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-80 |
80 |
rs10455872 |
0.161131 |
total lipids in large VLDL (EFO:0022175)
|
PMID:36764567 |
GWAS682922_H |
GCST90269588 |
Cholesterol in very large VLDL (UKB data field 23491) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-69 |
69 |
rs10455872 |
0.150916 |
cholesterol in very large VLDL measurement (EFO:0022230)
|
PMID:36764567 |
GWAS683689_H |
GCST90269554 |
Docosahexaenoic acid to total fatty acids percentage (UKB data field 23457) |
88,268 European ancestry individuals |
G |
0.0797288 |
2E-23 |
22.699 |
rs10455872 |
0.0839134 |
docosahexaenoic acid to total fatty acids percentage (EFO:0022262)
|
PMID:36764567 |
GWAS683729_H |
GCST90269594 |
Phospholipids in large VLDL (UKB data field 23497) |
88,329 European ancestry individuals |
G |
0.0797473 |
7E-72 |
71.155 |
rs10455872 |
0.151749 |
phospholipids in large VLDL measurement (EFO:0022169)
|
PMID:36764567 |
GWAS684016_H |
GCST90269551 |
Monounsaturated fatty acids to total fatty acids percentage (UKB data field 23454) |
88,268 European ancestry individuals |
G |
0.0797288 |
4E-52 |
51.398 |
rs10455872 |
0.128279 |
monounsaturated fatty acids (EFO:0022187)
|
PMID:36764567 |
GWAS684796_H |
GCST90269590 |
Free cholesterol in very large VLDL (UKB data field 23493) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-97 |
96.699 |
rs10455872 |
0.177861 |
free cholesterol in very large VLDL measurement (EFO:0022274)
|
PMID:36764567 |
GWAS685412_H |
GCST90269587 |
Phospholipids in very large VLDL (UKB data field 23490) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-104 |
103.699 |
rs10455872 |
0.183573 |
phospholipids in very large VLDL measurement (EFO:0022299)
|
PMID:36764567 |
GWAS685764_H |
GCST90269647 |
Triglycerides in small LDL (UKB data field 23550) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-95 |
94.699 |
rs10455872 |
0.176347 |
triglycerides in small LDL measurement (EFO:0022323)
|
PMID:36764567 |
GWAS685891_H |
GCST90269612 |
Triglycerides in small VLDL (UKB data field 23515) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-51 |
51 |
rs10455872 |
0.128274 |
triglycerides in small VLDL measurement (EFO:0022145)
|
PMID:36764567 |
GWAS686116_H |
GCST90302118 |
Total fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-17 |
16.699 |
rs10455872 |
0.0725 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS686419_H |
GCST90269550 |
Polyunsaturated fatty acids to total fatty acids percentage (UKB data field 23453) |
88,268 European ancestry individuals |
G |
0.0797288 |
5E-57 |
56.302 |
rs10455872 |
0.134025 |
polyunsaturated fatty acids to total fatty acids percentage (EFO:0022303)
|
PMID:36764567 |
GWAS686721_H |
GCST90269552 |
Saturated fatty acids to total fatty acids percentage (UKB data field 23455) |
88,268 European ancestry individuals |
G |
0.0797288 |
2E-20 |
19.699 |
rs10455872 |
0.0793897 |
saturated fatty acids to total fatty acids percentage (EFO:0022305)
|
PMID:36764567 |
GWAS687068_H |
GCST90269597 |
Free cholesterol in large VLDL (UKB data field 23500) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-65 |
64.398 |
rs10455872 |
0.144606 |
free cholesterol in large VLDL measurement (EFO:0022265)
|
PMID:36764567 |
GWAS688356_H |
GCST90269545 |
Saturated fatty acids levels (UKB data field 23448) |
88,268 European ancestry individuals |
G |
0.0797288 |
1E-54 |
54 |
rs10455872 |
0.134131 |
saturated fatty acids measurement (EFO:0022304)
|
PMID:36764567 |
GWAS688768_H |
GCST90269586 |
Total lipids in very large VLDL (UKB data field 23489) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-110 |
110 |
rs10455872 |
0.188547 |
total lipids in very large VLDL measurement (EFO:0022313)
|
PMID:36764567 |
GWAS688849_H |
GCST90269521 |
Total lipids in VLDL (UKB data field 23424) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-73 |
72.398 |
rs10455872 |
0.155161 |
total lipids in VLDL measurement (EFO:0022314)
|
PMID:36764567 |
GWAS689217_H |
GCST90269582 |
Cholesteryl esters in chylomicrons and extremely large VLDL (UKB data field 23485) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-138 |
138 |
rs10455872 |
0.212287 |
cholesteryl ester measurement (EFO:0010351)
|
PMID:36764567 |
GWAS689292_H |
GCST002675 |
Response to statins (LDL cholesterol change) |
18,596 European ancestry individuals |
G |
0.087 |
7E-44 |
43.155 |
rs10455872 |
0.052 |
response to statin (GO:0036273) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:25350695 |
GWAS689512_H |
GCST90269581 |
Cholesterol in chylomicrons and extremely large VLDL (UKB data field 23484) |
88,329 European ancestry individuals |
G |
0.0797473 |
8E-155 |
154.097 |
rs10455872 |
0.224064 |
cholesterol in chylomicrons and extremely large VLDL measurement (EFO:0021898)
|
PMID:36764567 |
GWAS689769_H |
GCST90269598 |
Triglycerides in large VLDL (UKB data field 23501) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-107 |
106.699 |
rs10455872 |
0.185673 |
triglycerides in large VLDL measurement (EFO:0022178)
|
PMID:36764567 |
GWAS689976_H |
GCST90269578 |
Concentration of chylomicrons and extremely large VLDL particles (UKB data field 23481) |
88,329 European ancestry individuals |
G |
0.0797473 |
9E-179 |
178.046 |
rs10455872 |
0.240045 |
concentration of chylomicrons and extremely large VLDL particles measurement (EFO:0022260)
|
PMID:36764567 |
None Available |
GCST90269532 |
Triglycerides to phosphoglycerides ratio (UKB data field 23435) |
88,268 European ancestry individuals |
G |
0.0797288 |
2E-97 |
96.699 |
rs10455872 |
0.1712 |
triglycerides to phosphoglycerides ratio (EFO:0022327)
|
PMID:36764567 |
GWAS690075_H |
GCST90269585 |
Concentration of very large VLDL particles (UKB data field 23488) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-99 |
98.398 |
rs10455872 |
0.178171 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:36764567 |
GWAS690091_H |
GCST90269605 |
Triglycerides in medium VLDL (UKB data field 23508) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-63 |
62.523 |
rs10455872 |
0.14292 |
triglycerides in medium VLDL measurement (EFO:0022155)
|
PMID:36764567 |
GWAS690167_H |
GCST90269544 |
Monounsaturated fatty acids levels (UKB data field 23447) |
88,268 European ancestry individuals |
G |
0.0797288 |
4E-64 |
63.398 |
rs10455872 |
0.145988 |
monounsaturated fatty acids (EFO:0022187)
|
PMID:36764567 |
GWAS690199_H |
GCST90269580 |
Phospholipids in chylomicrons and extremely large VLDL (UKB data field 23483) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-174 |
174 |
rs10455872 |
0.236795 |
phospholipids in chylomicrons and extremely large VLDL measurement (EFO:0022292)
|
PMID:36764567 |
GWAS690450_H |
GCST90302121 |
Estimated degree of unsaturation |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
7E-24 |
23.155 |
rs10455872 |
0.0875 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS690554_H |
GCST90269583 |
Free cholesterol in chylomicrons and extremely large VLDL (UKB data field 23486) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-172 |
171.523 |
rs10455872 |
0.236125 |
free cholesterol in chylomicrons and extremely large VLDL measurement (EFO:0022263)
|
PMID:36764567 |
GWAS690877_H |
GCST90269505 |
Triglycerides in VLDL (UKB data field 23408) |
88,329 European ancestry individuals |
G |
0.0797473 |
9E-117 |
116.046 |
rs10455872 |
0.193692 |
triglycerides in VLDL measurement (EFO:0022326)
|
PMID:36764567 |
GWAS691104_H |
GCST90269504 |
Total triglycerides levels (UKB data field 23407) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-97 |
96.523 |
rs10455872 |
0.177145 |
triglyceride measurement (EFO:0004530)
|
PMID:36764567 |
GWAS693051_H |
GCST90302110 |
Total lipids in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
4E-24 |
23.398 |
rs10455872 |
0.0856 |
total lipids in small VLDL (EFO:0022148)
|
PMID:38448586 |
GWAS694821_H |
GCST90302109 |
Free cholesterol to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9296 |
7E-43 |
42.155 |
rs10455872 |
0.1131 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS695823_H |
GCST90302115 |
Triglycerides to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
3E-52 |
51.523 |
rs10455872 |
0.131 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS696351_H |
GCST90302116 |
Ratio of triglycerides to phosphoglycerides |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9301 |
3E-71 |
70.523 |
rs10455872 |
0.1562 |
triglyceride measurement (EFO:0004530) phospholipid measurement (EFO:0004639)
|
PMID:38448586 |
GWAS697510_H |
GCST001865 |
Aortic-valve calcification |
6,942 European ancestry individuals |
G |
0.07 |
3E-11 |
10.523 |
rs10455872 |
2.05 |
aortic valve calcification (EFO:0005239)
|
PMID:23388002 |
None Available |
GCST90274223 |
Heart failure |
90,653 European ancestry cases, 1,188,957 European ancestry controls |
A |
NR |
8E-23 |
22.097 |
rs10455872 |
0.104 |
heart failure (EFO:0003144)
|
PMID:37429843 |
GWAS699304_H |
GCST90302114 |
Triglycerides in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-43 |
42.523 |
rs10455872 |
0.1174 |
triglycerides in small VLDL measurement (EFO:0022145)
|
PMID:38448586 |
GWAS700269_H |
GCST90302113 |
Phospholipids to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
3E-21 |
20.523 |
rs10455872 |
0.0819 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
None Available |
GCST90302165 |
Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9325 |
7E-28 |
27.155 |
rs10455872 |
0.0998 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS701957_H |
GCST90302124 |
Mean diameter of VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
2E-113 |
112.699 |
rs10455872 |
0.1971 |
very low density lipoprotein particle size measurement (EFO:0008594)
|
PMID:38448586 |
GWAS701988_H |
GCST90302159 |
Phospholipids to total lipids ratio in very small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-65 |
65 |
rs10455872 |
0.1431 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS702746_H |
GCST90302167 |
Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9329 |
2E-24 |
23.699 |
rs10455872 |
0.0963 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS703226_H |
GCST90302123 |
Total cholesterol levels in VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-25 |
24.699 |
rs10455872 |
0.0881 |
total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS703973_H |
GCST90302170 |
Phospholipid levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-123 |
122.699 |
rs10455872 |
0.2012 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639)
|
PMID:38448586 |
GWAS704265_H |
GCST90302125 |
Triglyceride levels in VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-68 |
67.699 |
rs10455872 |
0.1489 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS705378_H |
GCST90302166 |
Free cholesterol levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-115 |
114.523 |
rs10455872 |
0.1943 |
free cholesterol measurement (EFO:0008591) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
None Available |
GCST90301953 |
Diacylglycerol levels |
74,743 Non-Finnish European ancestry individuals |
A |
0.9224 |
2E-26 |
25.699 |
rs10455872 |
0.1142 |
diglyceride measurement (EFO:0010223)
|
PMID:38448586 |
GWAS706076_H |
GCST90301950 |
Conjugated linoleic acid |
70,413 Non-Finnish European ancestry individuals |
A |
0.9219 |
6E-11 |
10.222 |
rs10455872 |
0.0763 |
linoleic acid measurement (EFO:0006807)
|
PMID:38448586 |
GWAS706744_H |
GCST90301958 |
Estimated description of fatty acid chain length not actual carbon number |
74,743 Non-Finnish European ancestry individuals |
A |
0.9224 |
1E-47 |
47 |
rs10455872 |
0.1603 |
fatty acid change measurement (EFO:0020875)
|
PMID:38448586 |
None Available |
GCST009821 |
Response to statins (LDL cholesterol percent change) |
28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals |
G |
0.068 |
4E-30 |
29.398 |
rs10455872 |
0.179 |
response to statin (GO:0036273) LDL cholesterol change measurement (EFO:0007804)
|
PMID:31969989 |
GWAS708874_H |
GCST010337 |
Low density lipoprotein cholesterol levels (on statin treatment) |
28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals |
G |
0.068 |
2E-34 |
33.699 |
rs10455872 |
0.042 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:31969989 |
GWAS708882_H |
GCST010338 |
Response to statins (LDL cholesterol change) |
28,616 European ancestry individuals, 1,205 African ancestry individuals, 2,350 East Asian ancestry individuals, 2,703 Hispanic/Latino individuals |
G |
0.068 |
1E-33 |
33 |
rs10455872 |
0.042 |
response to statin (GO:0036273) LDL cholesterol change measurement (EFO:0007804)
|
PMID:31969989 |
GWAS709264_H |
GCST90302169 |
Concentration of chylomicrons and extremely large VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
5E-123 |
122.302 |
rs10455872 |
0.2009 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS710013_H |
GCST90302168 |
Total lipid levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-122 |
122 |
rs10455872 |
0.2005 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529)
|
PMID:38448586 |
None Available |
GCST001408 |
Response to statins (LDL cholesterol change) |
6,989 European ancestry individuals |
? |
NR |
5E-15 |
14.302 |
rs10455872 |
6.8 |
response to statin (GO:0036273) LDL cholesterol change measurement (EFO:0007804)
|
PMID:22331829 |
GWAS711298_H |
GCST90301968 |
Glycoprotein acetylation |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 113,034 European ancestry individuals |
A |
0.9285 |
9E-34 |
33.046 |
rs10455872 |
0.1051 |
glycoprotein measurement (EFO:0004555)
|
PMID:38448586 |
GWAS715611_H |
GCST007143 |
Total cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
A |
0.933 |
6E-41 |
40.222 |
rs10455872 |
0.123 |
total cholesterol measurement (EFO:0004574)
|
PMID:29507422 |
GWAS715612_H |
GCST007143 |
Total cholesterol levels |
76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals |
A |
NR |
2E-43 |
42.699 |
rs10455872 |
0.123 |
total cholesterol measurement (EFO:0004574)
|
PMID:29507422 |
GWAS716248_H |
GCST006700 |
Parental longevity (father's age at death) |
317,652 British ancestry individuals |
A |
0.92 |
5E-7 |
6.302 |
rs10455872 |
0.0247 |
parental longevity (EFO:0007796)
|
PMID:29227965 |
GWAS716426_H |
GCST90302161 |
Triglycerides to total lipids ratio in very small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
7E-26 |
25.155 |
rs10455872 |
0.091 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS716537_H |
GCST90302164 |
Cholesteryl ester levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
8E-91 |
90.097 |
rs10455872 |
0.1721 |
cholesteryl ester measurement (EFO:0010351) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS716731_H |
GCST006698 |
Parental longevity (both parents in top 10%) |
7,182 cases, 79,767 controls |
A |
0.92 |
2E-8 |
7.699 |
rs10455872 |
0.0202 |
parental longevity (EFO:0007796)
|
PMID:29227965 |
GWAS716736_H |
GCST006699 |
Parental longevity (mother's age at death) |
246,941 British ancestry individuals |
A |
0.92 |
2E-7 |
6.699 |
rs10455872 |
0.0265 |
parental longevity (EFO:0007796)
|
PMID:29227965 |
GWAS717359_H |
GCST90302171 |
Phospholipids to total lipids ratio in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9325 |
7E-41 |
40.155 |
rs10455872 |
0.122 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS718604_H |
GCST90302162 |
Total cholesterol levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-103 |
102.699 |
rs10455872 |
0.1839 |
chylomicron measurement (EFO:0008596) total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS718760_H |
GCST90302172 |
Triglyceride levels in chylomicrons and extremely large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-126 |
125.523 |
rs10455872 |
0.2035 |
chylomicron measurement (EFO:0008596) triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS718944_H |
GCST90301973 |
Triglyceride levels in HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
4E-21 |
20.398 |
rs10455872 |
0.0803 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS723011_H |
GCST90269680 |
Triglycerides to total lipids in chylomicrons and extremely large VLDL percentage (UKB data field 23583) |
85,701 European ancestry individuals |
G |
0.0785697 |
1E-194 |
194 |
rs10455872 |
0.263751 |
triglycerides to total lipids in chylomicrons and extremely large VLDL percentage (EFO:0022328)
|
PMID:36764567 |
GWAS724132_H |
GCST90269682 |
Cholesterol to total lipids in very large VLDL percentage (UKB data field 23585) |
87,620 European ancestry individuals |
G |
0.0795309 |
1E-158 |
158 |
rs10455872 |
0.225483 |
cholesterol to total lipids in very large VLDL percentage (EFO:0022244)
|
PMID:36764567 |
GWAS724943_H |
GCST90301962 |
Ratio of omega-6 fatty acids to total fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9305 |
4E-46 |
45.398 |
rs10455872 |
0.1232 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS726071_H |
GCST005561 |
Aortic valve stenosis |
2,457 Icelandic ancestry cases, 349,342 Icelandic ancestry controls (including non-array genotyped, whole genome imputed individuals) |
G |
0.062 |
2E-31 |
30.699 |
rs10455872 |
1.46 |
aortic stenosis (EFO:0000266)
|
PMID:29511194 |
GWAS726873_H |
GCST90269698 |
Cholesteryl esters to total lipids in small VLDL percentage (UKB data field 23601) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-62 |
61.699 |
rs10455872 |
0.144573 |
cholesteryl esters to total lipids in small VLDL percentage (EFO:0022256)
|
PMID:36764567 |
GWAS726980_H |
GCST90269709 |
Free cholesterol to total lipids in IDL percentage (UKB data field 23612) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-14 |
13.699 |
rs10455872 |
0.0664027 |
free cholesterol to total lipids in IDL percentage (EFO:0022278)
|
PMID:36764567 |
GWAS727002_H |
GCST90302004 |
Phospholipids to total lipids ratio in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9294 |
3E-10 |
9.523 |
rs10455872 |
0.0536 |
phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS727203_H |
GCST90302024 |
Free cholesterol to total lipids ratio in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9328 |
2E-40 |
39.699 |
rs10455872 |
0.1235 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS727936_H |
GCST004787 |
Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) |
18,467 European and unknown ancestry cases, 45,264 European and unknown ancestry controls |
G |
0.065 |
2E-49 |
48.699 |
rs10455872 |
1.31 |
coronary artery disease (EFO:0001645)
|
PMID:28714975 |
GWAS728527_H |
GCST90269697 |
Cholesterol to total lipids in small VLDL percentage (UKB data field 23600) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-60 |
59.523 |
rs10455872 |
0.139987 |
cholesterol to total lipids in small VLDL percentage (EFO:0022242)
|
PMID:36764567 |
GWAS729092_H |
GCST90302023 |
Free cholesterol in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
8E-86 |
85.097 |
rs10455872 |
0.1672 |
free cholesterol in large VLDL measurement (EFO:0022265)
|
PMID:38448586 |
None Available |
GCST90302022 |
Cholesteryl esters to total lipids ratio in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9319 |
2E-26 |
25.699 |
rs10455872 |
0.094 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS730238_H |
GCST90245361 |
Palmitoyl sphingomyelin (d18:1/16:0) levels |
14,296 European ancestry individuals |
A |
0.9216 |
2E-10 |
9.699 |
rs10455872 |
0.11852267 |
palmitoyl sphingomyelin (d18:1/16:0) measurement (EFO:0800300)
|
PMID:36357675 |
GWAS730462_H |
GCST90269699 |
Free cholesterol to total lipids in small VLDL percentage (UKB data field 23602) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-42 |
42 |
rs10455872 |
0.114712 |
free cholesterol to total lipids in small VLDL percentage (EFO:0022287)
|
PMID:36764567 |
GWAS731151_H |
GCST90269700 |
Triglycerides to total lipids in small VLDL percentage (UKB data field 23603) |
88,329 European ancestry individuals |
G |
0.0797473 |
8E-56 |
55.097 |
rs10455872 |
0.133821 |
triglycerides to total lipids in small VLDL percentage (EFO:0022338)
|
PMID:36764567 |
GWAS732375_H |
GCST90269708 |
Cholesteryl esters to total lipids in IDL percentage (UKB data field 23611) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-11 |
10.398 |
rs10455872 |
0.0562647 |
cholesteryl esters to total lipids in IDL percentage (EFO:0022247)
|
PMID:36764567 |
None Available |
GCST90302036 |
Free cholesterol to total lipids ratio in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9294 |
2E-26 |
25.699 |
rs10455872 |
0.0883 |
free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS733326_H |
GCST90302008 |
Total cholesterol to total lipids ratio in large LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
6E-19 |
18.222 |
rs10455872 |
0.0747 |
cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:38448586 |
GWAS734799_H |
GCST90269730 |
Triglycerides to total lipids in very large HDL percentage (UKB data field 23633) |
88,307 European ancestry individuals |
G |
0.0797445 |
1E-32 |
32 |
rs10455872 |
0.0982788 |
triglycerides to total lipids in very large HDL percentage (EFO:0022339)
|
PMID:36764567 |
None Available |
GCST90301984 |
Phospholipids to total lipids ratio in IDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
4E-11 |
10.398 |
rs10455872 |
0.0556 |
phospholipids:total lipids ratio (EFO:0020946) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:38448586 |
None Available |
GCST90302041 |
Triglycerides in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
2E-23 |
22.699 |
rs10455872 |
0.0871 |
triglycerides in medium HDL measurement (EFO:0022321)
|
PMID:38448586 |
None Available |
GCST90269707 |
Cholesterol to total lipids in IDL percentage (UKB data field 23610) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-16 |
15.699 |
rs10455872 |
0.0703495 |
cholesterol to total lipids in IDL percentage (EFO:0022233)
|
PMID:36764567 |
GWAS736489_H |
GCST90302021 |
Cholesterol esters in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
6E-82 |
81.222 |
rs10455872 |
0.1635 |
cholesterol esters in large VLDL measurement (EFO:0022170)
|
PMID:38448586 |
GWAS736513_H |
GCST90302029 |
Triglycerides in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-85 |
84.523 |
rs10455872 |
0.1668 |
triglycerides in large VLDL measurement (EFO:0022178)
|
PMID:38448586 |
GWAS737480_H |
GCST90269694 |
Free cholesterol to total lipids in medium VLDL percentage (UKB data field 23597) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-61 |
61 |
rs10455872 |
0.138721 |
free cholesterol to total lipids in medium VLDL percentage (EFO:0022284)
|
PMID:36764567 |
GWAS737509_H |
GCST90301989 |
Ratio of 18:2 linoleic acid to total fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
1E-26 |
26 |
rs10455872 |
0.0876 |
fatty acid measurement (EFO:0005110) linoleic acid measurement (EFO:0006807)
|
PMID:38448586 |
GWAS737788_H |
GCST90269693 |
Cholesteryl esters to total lipids in medium VLDL percentage (UKB data field 23596) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-70 |
69.699 |
rs10455872 |
0.146429 |
cholesteryl esters to total lipids in medium VLDL percentage (EFO:0022253)
|
PMID:36764567 |
GWAS737870_H |
GCST90302019 |
Total Cholesterol in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-85 |
84.699 |
rs10455872 |
0.167 |
total cholesterol in large VLDL (EFO:0022177)
|
PMID:38448586 |
GWAS737909_H |
GCST90301980 |
Free cholesterol to total lipids ratio in IDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
4E-67 |
66.398 |
rs10455872 |
0.1435 |
free cholesterol:total lipids ratio (EFO:0020945) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:38448586 |
GWAS738886_H |
GCST90269675 |
Triglycerides in small HDL (UKB data field 23578) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-33 |
32.699 |
rs10455872 |
0.102567 |
triglycerides in small HDL measurement (EFO:0022158)
|
PMID:36764567 |
GWAS739383_H |
GCST90269741 |
Phospholipids to total lipids in small HDL percentage (UKB data field 23644) |
88,329 European ancestry individuals |
G |
0.0797473 |
9E-11 |
10.046 |
rs10455872 |
0.0548952 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
None Available |
GCST90302000 |
Free cholesterol to total lipids ratio in large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9296 |
2E-20 |
19.699 |
rs10455872 |
0.0795 |
free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS739808_H |
GCST90269695 |
Triglycerides to total lipids in medium VLDL percentage (UKB data field 23598) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-63 |
63 |
rs10455872 |
0.139934 |
triglycerides to total lipids in medium VLDL percentage (EFO:0022335)
|
PMID:36764567 |
None Available |
GCST90269696 |
Phospholipids to total lipids in small VLDL percentage (UKB data field 23599) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-41 |
40.398 |
rs10455872 |
0.112873 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
None Available |
GCST90302042 |
Triglycerides to total lipids ratio in medium HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-20 |
19.699 |
rs10455872 |
0.0784 |
triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
None Available |
GCST90302012 |
Free cholesterol to total lipids ratio in large LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
2E-26 |
25.699 |
rs10455872 |
0.0904 |
low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS740900_H |
GCST90269742 |
Cholesterol to total lipids in small HDL percentage (UKB data field 23645) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-37 |
37 |
rs10455872 |
0.11048 |
cholesterol to total lipids in small HDL percentage (EFO:0022240)
|
PMID:36764567 |
None Available |
GCST90302026 |
Concentration of large VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-85 |
84.523 |
rs10455872 |
0.1669 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS743509_H |
GCST90269714 |
Free cholesterol to total lipids in large LDL percentage (UKB data field 23617) |
88,329 European ancestry individuals |
G |
0.0797473 |
8E-39 |
38.097 |
rs10455872 |
0.109213 |
free cholesterol to total lipids in large LDL percentage (EFO:0022280)
|
PMID:36764567 |
GWAS744734_H |
GCST90302046 |
Cholesteryl esters to total lipids ratio in medium LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-31 |
31 |
rs10455872 |
0.0976 |
low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS744940_H |
GCST90269702 |
Cholesterol to total lipids in very small VLDL percentage (UKB data field 23605) |
88,329 European ancestry individuals |
G |
0.0797473 |
4E-32 |
31.398 |
rs10455872 |
0.0982062 |
cholesterol to total lipids in very small VLDL percentage (EFO:0022245)
|
PMID:36764567 |
GWAS745095_H |
GCST90269703 |
Cholesteryl esters to total lipids in very small VLDL percentage (UKB data field 23606) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-30 |
30 |
rs10455872 |
0.0952571 |
cholesteryl esters to total lipids in very small VLDL percentage (EFO:0022259)
|
PMID:36764567 |
GWAS745741_H |
GCST90269744 |
Free cholesterol to total lipids in small HDL percentage (UKB data field 23647) |
88,329 European ancestry individuals |
G |
0.0797473 |
8E-14 |
13.097 |
rs10455872 |
0.0624976 |
free cholesterol to total lipids in small HDL percentage (EFO:0022285)
|
PMID:36764567 |
GWAS745948_H |
GCST90269688 |
Cholesteryl esters to total lipids in large VLDL percentage (UKB data field 23591) |
88,321 European ancestry individuals |
G |
0.0797432 |
9E-166 |
165.046 |
rs10455872 |
0.230314 |
cholesteryl esters to total lipids in large VLDL percentage (EFO:0022250)
|
PMID:36764567 |
GWAS745984_H |
GCST90269743 |
Cholesteryl esters to total lipids in small HDL percentage (UKB data field 23646) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-29 |
28.523 |
rs10455872 |
0.0963554 |
cholesteryl esters to total lipids in small HDL percentage (EFO:0022254)
|
PMID:36764567 |
GWAS746366_H |
GCST90269692 |
Cholesterol to total lipids in medium VLDL percentage (UKB data field 23595) |
88,329 European ancestry individuals |
G |
0.0797473 |
7E-70 |
69.155 |
rs10455872 |
0.146367 |
cholesterol to total lipids in medium VLDL percentage (EFO:0022239)
|
PMID:36764567 |
GWAS746383_H |
GCST90269691 |
Phospholipids to total lipids in medium VLDL percentage (UKB data field 23594) |
88,329 European ancestry individuals |
G |
0.0797473 |
5E-35 |
34.302 |
rs10455872 |
0.104216 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
GWAS747166_H |
GCST90302027 |
Phospholipids in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-81 |
81 |
rs10455872 |
0.1631 |
phospholipids in VLDL measurement (EFO:0022301)
|
PMID:38448586 |
None Available |
GCST90302025 |
Total lipids in large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-85 |
84.699 |
rs10455872 |
0.1669 |
total lipids in large VLDL (EFO:0022175)
|
PMID:38448586 |
GWAS748453_H |
GCST90269723 |
Cholesteryl esters to total lipids in small LDL percentage (UKB data field 23626) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-66 |
65.699 |
rs10455872 |
0.150386 |
cholesteryl esters to total lipids in small LDL percentage (EFO:0022255)
|
PMID:36764567 |
None Available |
GCST90269721 |
Phospholipids to total lipids in small LDL percentage (UKB data field 23624) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-66 |
65.699 |
rs10455872 |
0.150327 |
phospholipids:total lipids ratio (EFO:0020946)
|
PMID:36764567 |
None Available |
GCST90269738 |
Cholesteryl esters to total lipids in medium HDL percentage (UKB data field 23641) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-24 |
23.523 |
rs10455872 |
0.0862788 |
cholesteryl esters to total lipids in medium HDL percentage (EFO:0022251)
|
PMID:36764567 |
GWAS750646_H |
GCST90269710 |
Triglycerides to total lipids in IDL percentage (UKB data field 23613) |
88,329 European ancestry individuals |
G |
0.0797473 |
7E-18 |
17.155 |
rs10455872 |
0.0728059 |
triglycerides to total lipids in IDL percentage (EFO:0022329)
|
PMID:36764567 |
GWAS752028_H |
GCST90269720 |
Triglycerides to total lipids in medium LDL percentage (UKB data field 23623) |
88,329 European ancestry individuals |
G |
0.0797473 |
7E-29 |
28.155 |
rs10455872 |
0.0958806 |
triglycerides to total lipids in medium LDL percentage (EFO:0022334)
|
PMID:36764567 |
GWAS752648_H |
GCST90269719 |
Free cholesterol to total lipids in medium LDL percentage (UKB data field 23622) |
88,329 European ancestry individuals |
G |
0.0797473 |
2E-87 |
86.699 |
rs10455872 |
0.166597 |
free cholesterol to total lipids in medium LDL percentage (EFO:0022283)
|
PMID:36764567 |
None Available |
GCST90269507 |
Triglycerides in HDL (UKB data field 23410) |
88,329 European ancestry individuals |
G |
0.0797473 |
1E-30 |
30 |
rs10455872 |
0.098973 |
triglycerides in HDL measurement (EFO:0022317)
|
PMID:36764567 |
GWAS765191_H |
GCST90269555 |
Polyunsaturated fatty acids to monounsaturated fatty acids ratio (UKB data field 23458) |
88,268 European ancestry individuals |
G |
0.0797288 |
4E-57 |
56.398 |
rs10455872 |
0.134211 |
polyunsaturated fatty acids to monounsaturated fatty acids ratio (EFO:0022302)
|
PMID:36764567 |
GWAS768242_H |
GCST90269654 |
Triglycerides in very large HDL (UKB data field 23557) |
88,329 European ancestry individuals |
G |
0.0797473 |
3E-53 |
52.523 |
rs10455872 |
0.131215 |
triglycerides in very large HDL measurement (EFO:0022324)
|
PMID:36764567 |
GWAS769890_H |
GCST90302072 |
Ratio of polyunsaturated fatty acids to total fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-45 |
44.699 |
rs10455872 |
0.1171 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS769931_H |
GCST90302081 |
Cholesterol esters in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-44 |
43.523 |
rs10455872 |
0.1172 |
esterified cholesterol measurement (EFO:0008589) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
None Available |
GCST90302084 |
Free cholesterol to total lipids ratio in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-34 |
33.699 |
rs10455872 |
0.1033 |
free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS770540_H |
GCST90302080 |
Total cholesterol to total lipids ratio in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
6E-63 |
62.222 |
rs10455872 |
0.1395 |
cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS770694_H |
GCST90302068 |
Triglycerides to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
5E-25 |
24.302 |
rs10455872 |
0.0886 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS770855_H |
GCST90302089 |
Triglycerides in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
3E-23 |
22.523 |
rs10455872 |
0.0869 |
triglycerides in small HDL measurement (EFO:0022158)
|
PMID:38448586 |
GWAS770935_H |
GCST90302066 |
Phospholipids to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-59 |
59 |
rs10455872 |
0.1353 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS771484_H |
GCST90302094 |
Cholesteryl esters to total lipids ratio in small LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
1E-39 |
39 |
rs10455872 |
0.11 |
cholesterol:total lipids ratio (EFO:0020943) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS771953_H |
GCST90302076 |
Serum total triglyceride levels |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
7E-51 |
50.155 |
rs10455872 |
0.1279 |
triglyceride measurement (EFO:0004530)
|
PMID:38448586 |
None Available |
GCST90302082 |
Cholesteryl esters to total lipids ratio in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
4E-64 |
63.398 |
rs10455872 |
0.1409 |
cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS772406_H |
GCST90302065 |
Phospholipids in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
8E-59 |
58.097 |
rs10455872 |
0.1378 |
phospholipids in VLDL measurement (EFO:0022301)
|
PMID:38448586 |
GWAS772543_H |
GCST90302079 |
Total cholesterol levels in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
5E-29 |
28.302 |
rs10455872 |
0.0939 |
total cholesterol measurement (EFO:0004574) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS772861_H |
GCST90302044 |
Total cholesterol to total lipids ratio in medium LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-39 |
38.523 |
rs10455872 |
0.1093 |
cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:38448586 |
None Available |
GCST90302077 |
Saturated fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
6E-19 |
18.222 |
rs10455872 |
0.0762 |
saturated fatty acids measurement (EFO:0022304)
|
PMID:38448586 |
GWAS772991_H |
GCST90302067 |
Triglycerides in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-69 |
68.699 |
rs10455872 |
0.15 |
triglycerides in medium VLDL measurement (EFO:0022155)
|
PMID:38448586 |
GWAS773167_H |
GCST90302088 |
Phospholipids to total lipids ratio in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
2E-44 |
43.699 |
rs10455872 |
0.1205 |
phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS774293_H |
GCST90302063 |
Total lipids in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-63 |
62.699 |
rs10455872 |
0.1432 |
total lipids in medium VLDL (EFO:0022153)
|
PMID:38448586 |
GWAS775476_H |
GCST90302057 |
Total cholesterol in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
8E-50 |
49.097 |
rs10455872 |
0.1264 |
total cholesterol in medium VLDL (EFO:0022162)
|
PMID:38448586 |
GWAS776095_H |
GCST90302056 |
Ratio of monounsaturated fatty acids to total fatty acids |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
5E-37 |
36.302 |
rs10455872 |
0.1097 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS776188_H |
GCST90302100 |
Phospholipids to total lipids ratio in small LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
7E-30 |
29.155 |
rs10455872 |
0.0976 |
low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS777365_H |
GCST90302062 |
Free cholesterol to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
4E-17 |
16.398 |
rs10455872 |
0.0697 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS777406_H |
GCST90302092 |
Total cholesterol to total lipids ratio in small LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
9E-49 |
48.046 |
rs10455872 |
0.1224 |
cholesterol:total lipids ratio (EFO:0020943) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:38448586 |
None Available |
GCST90295949 |
Triglyceride to HDL cholesterol ratio |
402,398 European ancestry individuals |
A |
0.9209 |
5E-15 |
14.302 |
rs10455872 |
0.0455 |
triglyceride:HDL cholesterol ratio (EFO:0007929)
|
PMID:38200128 |
None Available |
GCST90302102 |
Triglycerides to total lipids ratio in small LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.93 |
2E-31 |
30.699 |
rs10455872 |
0.1012 |
triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:38448586 |
GWAS778602_H |
GCST90302061 |
Free cholesterol in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
5E-59 |
58.302 |
rs10455872 |
0.1379 |
free cholesterol in medium VLDL measurement (EFO:0022269)
|
PMID:38448586 |
GWAS778897_H |
GCST90302090 |
Triglycerides to total lipids ratio in small HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-24 |
24 |
rs10455872 |
0.0864 |
triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS779557_H |
GCST90302127 |
Total cholesterol to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9292 |
2E-22 |
21.699 |
rs10455872 |
0.0823 |
cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS779763_H |
GCST90295951 |
Triglyceride to HDL cholesterol ratio |
216,649 European ancestry individuals |
A |
0.9208 |
1E-10 |
10 |
rs10455872 |
0.0433 |
triglyceride:HDL cholesterol ratio (EFO:0007929)
|
PMID:38200128 |
GWAS780550_H |
GCST90302129 |
Cholesteryl esters to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9294 |
1E-17 |
17 |
rs10455872 |
0.0724 |
cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS781777_H |
GCST90295950 |
Triglyceride to HDL cholesterol ratio |
185,749 European ancestry individuals |
A |
0.921 |
7E-12 |
11.155 |
rs10455872 |
0.0482 |
triglyceride:HDL cholesterol ratio (EFO:0007929)
|
PMID:38200128 |
None Available |
GCST90302055 |
Monounsaturated fatty acids (16:1, 18:1) levels |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
1E-32 |
32 |
rs10455872 |
0.102 |
fatty acid measurement (EFO:0005110)
|
PMID:38448586 |
GWAS783698_H |
GCST90302052 |
Phospholipids to total lipids ratio in medium LDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9299 |
1E-40 |
40 |
rs10455872 |
0.1145 |
low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:38448586 |
GWAS784971_H |
GCST90302135 |
Phospholipids to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-35 |
35 |
rs10455872 |
0.1062 |
phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS785124_H |
GCST90302060 |
Cholesteryl esters to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-32 |
31.699 |
rs10455872 |
0.0987 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS787461_H |
GCST90302058 |
Total cholesterol to total lipids ratio in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-19 |
19 |
rs10455872 |
0.0751 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:38448586 |
GWAS788225_H |
GCST90302136 |
Triglycerides in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
4E-27 |
26.398 |
rs10455872 |
0.0914 |
triglycerides in very large HDL measurement (EFO:0022324)
|
PMID:38448586 |
GWAS788489_H |
GCST90302140 |
Cholesterol esters in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-105 |
104.699 |
rs10455872 |
0.1858 |
very low density lipoprotein cholesterol measurement (EFO:0008317) esterified cholesterol measurement (EFO:0008589)
|
PMID:38448586 |
None Available |
GCST90302059 |
Cholesterol esters in medium VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-40 |
40 |
rs10455872 |
0.1135 |
cholesterol esters in medium VLDL measurement (EFO:0022182)
|
PMID:38448586 |
GWAS789241_H |
GCST90302139 |
Total cholesterol to total lipids ratio in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9344 |
4E-20 |
19.398 |
rs10455872 |
0.0879 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:38448586 |
None Available |
GCST90302138 |
Total cholesterol in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-107 |
106.699 |
rs10455872 |
0.1875 |
total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS789748_H |
GCST90302064 |
Concentration of medium VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
1E-64 |
64 |
rs10455872 |
0.1448 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS790255_H |
GCST90302137 |
Triglycerides to total lipids ratio in very large HDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9294 |
3E-25 |
24.523 |
rs10455872 |
0.0882 |
triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:38448586 |
GWAS790832_H |
GCST90302105 |
Total cholesterol to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
3E-40 |
39.523 |
rs10455872 |
0.1106 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:38448586 |
GWAS791692_H |
GCST90302142 |
Free cholesterol in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-106 |
105.699 |
rs10455872 |
0.1865 |
free cholesterol in very large VLDL measurement (EFO:0022274)
|
PMID:38448586 |
GWAS792846_H |
GCST90302141 |
Cholesteryl esters to total lipids ratio in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9343 |
1E-20 |
20 |
rs10455872 |
0.0885 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
GWAS793409_H |
GCST90302107 |
Cholesteryl esters to total lipids ratio in small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
3E-32 |
31.523 |
rs10455872 |
0.0987 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:38448586 |
None Available |
GCST90302144 |
Total lipids in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
2E-107 |
106.699 |
rs10455872 |
0.1876 |
total lipids in very large VLDL measurement (EFO:0022313)
|
PMID:38448586 |
GWAS795111_H |
GCST001218 |
Lp (a) levels |
1,450 European ancestry individuals |
G |
0.07 |
5E-39 |
38.302 |
rs10455872 |
1.28 |
lipoprotein A measurement (EFO:0006925)
|
PMID:21900290 |
GWAS795515_H |
GCST90302148 |
Triglycerides in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9298 |
3E-106 |
105.523 |
rs10455872 |
0.1866 |
triglycerides in very large VLDL measurement (EFO:0022325)
|
PMID:38448586 |
None Available |
GCST90302146 |
Phospholipids in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-104 |
103.699 |
rs10455872 |
0.1848 |
phospholipids in VLDL measurement (EFO:0022301)
|
PMID:38448586 |
GWAS796841_H |
GCST90302145 |
Concentration of very large VLDL particles |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
1E-107 |
107 |
rs10455872 |
0.1877 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
None Available |
GCST90302149 |
Triglycerides to total lipids ratio in very large VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 110,896 European ancestry individuals |
A |
0.9349 |
3E-10 |
9.523 |
rs10455872 |
0.0624 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:38448586 |
GWAS809548_H |
GCST90302155 |
Free cholesterol to total lipids ratio in very small VLDL |
4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals |
A |
0.9297 |
2E-46 |
45.699 |
rs10455872 |
0.1169 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:38448586 |
GWAS814669_H |
GCST90129548 |
Coronary artery disease or plasminogen activator inhibitor 1 levels (pleiotropy) |
172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 19,599 European ancestry individuals with measurements |
? |
NR |
3E-121 |
120.523 |
rs10455872 |
N/A |
coronary artery disease (EFO:0001645) plasminogen activator inhibitor 1 measurement (EFO:0004792)
|
PMID:35285134 |
GWAS824263_H |
GCST90085924 |
Body fat percentage or coronary artery disease (MTAG) |
89,297 European ancestry individuals with body fat percentage, 11,419 Korean ancestry, Indian ancestry, Jamaican ancestry individuals with body fat percentage, 61,289 European ancestry, East Asian ancestry, South Asian ancestry, African American, Hispanic cases with coronary artery disease, 134,524 European ancestry, East Asian ancestry, South Asian ancestry, African American, Hispanic controls without coronary artery disease |
? |
NR |
3E-28 |
27.523 |
rs10455872 |
0.3186 |
body fat percentage (EFO:0007800) coronary artery disease (EFO:0001645)
|
PMID:33910581 |
GWAS824506_H |
GCST90085925 |
Body fat percentage or heart failure (MTAG) |
89,297 European ancestry individuals with body fat percentage, 47,309 European ancestry cases with heart failure, 930,014 European ancestry controls without heart failure, 11,419 Korean ancestry, Indian Asian ancestry, Jamaican ancestry individuals with body fat percentage |
? |
NR |
4E-9 |
8.398 |
rs10455872 |
0.1057 |
heart failure (EFO:0003144) body fat percentage (EFO:0007800)
|
PMID:33910581 |
GWAS832008_H |
GCST90092871 |
Cholesteryl esters to total lipids ratio in large VLDL |
115,071 European ancestry individuals |
A |
0.921023 |
2E-213 |
212.699 |
rs10455872 |
0.228243 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
GWAS832215_H |
GCST90092878 |
Triglyceride levels in large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-141 |
140.523 |
rs10455872 |
0.185835 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS832301_H |
GCST90092869 |
Cholesterol to total lipids ratio in large VLDL |
115,071 European ancestry individuals |
A |
0.921023 |
2E-180 |
179.699 |
rs10455872 |
0.214172 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
GWAS832568_H |
GCST90018793 |
Angina pectoris |
30,025 European ancestry cases, 440,906 European ancestry controls, 14,007 East Asian ancestry cases, 145,158 East Asian ancestry controls |
G |
NR |
8E-68 |
67.097 |
rs10455872 |
0.3358 |
angina pectoris (EFO:0003913)
|
PMID:34594039 |
GWAS832636_H |
GCST90132314 |
Coronary artery disease |
181,522 European ancestry, unknown cases, 984,168 European ancestry, unknown controls |
A |
0.932 |
2E-186 |
185.699 |
rs10455872 |
0.738 |
coronary artery disease (EFO:0001645)
|
PMID:36474045 |
GWAS836244_H |
GCST90092879 |
Triglycerides to total lipids ratio in large VLDL |
115,071 European ancestry individuals |
A |
0.921023 |
9E-69 |
68.046 |
rs10455872 |
0.133506 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
None Available |
GCST90092861 |
Free cholesterol to total lipids ratio in large LDL |
115,082 European ancestry individuals |
A |
0.921013 |
4E-52 |
51.398 |
rs10455872 |
0.110249 |
low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
None Available |
GCST90010853 |
Sphingomyeline C18:0 levels |
31,120 Caucasian ancestry individuals |
G |
0.0757 |
8E-14 |
13.097 |
rs10455872 |
7.478 |
sphingomyelin measurement (EFO:0010118)
|
PMID:33414548 |
GWAS847586_H |
GCST90129547 |
Coronary artery disease or tissue plasminogen activator levels (pleiotropy) |
172,122 European, South Asian or East Asian CAD cases, 566,864 European, South Asian or East Asian CAD controls, 26,929 European ancestry individuals with measurements |
? |
NR |
2E-121 |
120.699 |
rs10455872 |
N/A |
tissue plasminogen activator measurement (EFO:0004791) coronary artery disease (EFO:0001645)
|
PMID:35285134 |
GWAS848937_H |
GCST90399673 |
Abdominal aortic aneurysm |
58 African ancestry cases, 6,731 African ancestry controls, 77 Admixed American ancestry cases, 9,335 Admixed American ancestry controls, 1,155 East Asian ancestry cases, 173,601 East Asian ancestry controls, 8,163 European ancestry cases, 1,256,755 European ancestry controls |
G |
0.06486 |
6E-20 |
19.222 |
rs10455872 |
0.32087 |
Abdominal Aortic Aneurysm (EFO:0004214)
|
PMID:36777996 |
None Available |
GCST90315440 |
MGLL/PTPN6 protein level ratio |
43,509 European ancestry individuals |
? |
NR |
2E-17 |
16.699 |
rs10455872 |
0.105904 |
blood protein measurement (EFO:0007937)
|
PMID:38412862 |
GWAS860193_H |
GCST012232 |
Lipoprotein (a) levels |
348,591 European ancestry individuals, 6,000 African ancestry individuals, 9,116 Asian ancestry individuals, 7,505 individuals |
A |
NR |
4E-19380 |
19379.398 |
rs10455872 |
1.02095 |
lipoprotein A measurement (EFO:0006925)
|
PMID:33730874 |
None Available |
GCST90315439 |
MGLL/PLA2G4A protein level ratio |
43,509 European ancestry individuals |
? |
NR |
1E-17 |
17 |
rs10455872 |
0.106677 |
blood protein measurement (EFO:0007937)
|
PMID:38412862 |
GWAS861370_H |
GCST90018890 |
Peripheral artery disease |
7,114 European ancestry cases, 475,964 European ancestry controls, 4,112 East Asian ancestry cases, 173,601 East Asian ancestry controls |
G |
NR |
4E-13 |
12.398 |
rs10455872 |
0.2761 |
peripheral arterial disease (EFO:0004265)
|
PMID:34594039 |
GWAS866980_H |
GCST90399714 |
Heart failure |
1,170 Admixed American ancestry cases, 13,217 Admixed American ancestry controls, 710 South Asian ancestry cases, 30,071 South Asian ancestry controls, 1,367 African ancestry cases, 29,835 African ancestry controls, 12,665 East Asian ancestry cases, 245,263 East Asian ancestry controls, 52,496 European ancestry cases, 967,945 European ancestry controls |
G |
0.05857 |
3E-14 |
13.523 |
rs10455872 |
0.11551 |
heart failure (EFO:0003144)
|
PMID:36777996 |
None Available |
GCST004963 |
Lipoprotein phospholipase A2 activity in cardiovascular disease |
22,156 European, Asian, African, Arabic, Native American, Pacific Islander and other ancestry |
G |
0.05875 |
4E-13 |
12.398 |
rs10455872 |
7.22 |
lipoprotein-associated phospholipase A(2) measurement (EFO:0004746)
|
PMID:28753643 |
GWAS885384_H |
GCST90092817 |
Ratio of docosahexaenoic acid to total fatty acid levels |
115,006 European ancestry individuals |
A |
0.921013 |
1E-28 |
28 |
rs10455872 |
0.0822512 |
docosahexaenoic acid measurement (EFO:0007761) fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
None Available |
GCST90092842 |
Triglycerides to total lipids ratio in IDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-24 |
24 |
rs10455872 |
0.0752584 |
triglycerides:total lipids ratio (EFO:0020947) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:35213538 |
GWAS893361_H |
GCST90092836 |
Free cholesterol to total lipids ratio in IDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-18 |
17.699 |
rs10455872 |
0.0665856 |
free cholesterol:total lipids ratio (EFO:0020945) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:35213538 |
GWAS899112_H |
GCST90432152 |
Abdominal aortic aneurysm |
37,214 European ancestry cases, 997,776 European ancestry controls, 2,007 African ancestry cases, 88,331 African ancestry controls |
? |
NR |
2E-55 |
54.699 |
rs10455872 |
0.2367 |
Abdominal Aortic Aneurysm (EFO:0004214)
|
PMID:37845353 |
GWAS902497_H |
GCST90092929 |
Ratio of monounsaturated fatty acids to total fatty acids |
115,006 European ancestry individuals |
A |
0.921013 |
8E-70 |
69.097 |
rs10455872 |
0.129439 |
fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
None Available |
GCST90432175 |
Myocardial infarction |
3,950 Saudi Arabian ancestry cases, 2,324 Saudi Arabian ancestry controls, 56,278 European and unknown ancestry cases, 577,716 European and unknown ancestry controls |
? |
NR |
1E-81 |
81 |
rs10455872 |
0.7339 |
myocardial infarction (EFO:0000612)
|
PMID:38072966 |
GWAS906146_H |
GCST90092927 |
Triglycerides to total lipids ratio in medium VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-84 |
83.155 |
rs10455872 |
0.140047 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS907346_H |
GCST90092909 |
Free cholesterol to total lipids ratio in medium LDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-118 |
118 |
rs10455872 |
0.168768 |
low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
None Available |
GCST90310293 |
Calcific aortic valve stenosis |
14,819 European ancestry cases, 941,863 European ancestry controls |
G |
NR |
3E-61 |
60.523 |
rs10455872 |
N/A |
aortic stenosis (EFO:0000266) aortic valve calcification (EFO:0005239)
|
PMID:38494474 |
GWAS915323_H |
GCST90092829 |
Triglyceride levels in HDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-41 |
40.523 |
rs10455872 |
0.100693 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS917048_H |
GCST90061372 |
Peripheral artery disease in ever smokers |
7,404 Finnish ancestry cases, 205,693 Finnish ancestry controls, 7,404 non-Scandinavian ancestry cases, 205,693 non-Scandinavian ancestry controls, 7,404 British ancestry cases, 205,693 British ancestry controls |
G |
0.07 |
7E-11 |
10.155 |
rs10455872 |
1.3 |
peripheral arterial disease (EFO:0004265)
|
PMID:34601942 |
GWAS917162_H |
GCST90061375 |
Peripheral artery disease in non diabetes |
6,732 Finnish ancestry cases, 416,855 Finnish ancestry controls, 6,732 non-Scandinavian ancestry cases, 416,855 non-Scandinavian ancestry controls, 6,732 British ancestry cases, 416,855 British ancestry controls |
G |
0.08 |
1E-7 |
7 |
rs10455872 |
1.23 |
peripheral arterial disease (EFO:0004265)
|
PMID:34601942 |
None Available |
GCST90090991 |
Total cholesterol levels |
17,701 African American individuals, 22,954 Hispanics ancestry individuals, 2,387 East Asian ancestry individuals, 1,915 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 340 individuals, 22,912 European ancestry individuals |
? |
NR |
2E-15 |
14.699 |
rs10455872 |
0.198 |
total cholesterol measurement (EFO:0004574)
|
PMID:32226016 |
GWAS918429_H |
GCST90092832 |
Cholesterol to total lipids ratio in IDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-22 |
22 |
rs10455872 |
0.0729487 |
cholesterol:total lipids ratio (EFO:0020943) intermediate density lipoprotein measurement (EFO:0008595)
|
PMID:35213538 |
GWAS924845_H |
GCST90132734 |
Mean diameter of VLDL particles |
19,273 European ancestry individuals |
G |
0.04 |
1E-12 |
12 |
rs10455872 |
0.2 |
very low density lipoprotein particle size measurement (EFO:0008594)
|
PMID:27005778 |
None Available |
GCST90092902 |
Triglyceride levels in medium HDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-35 |
35 |
rs10455872 |
0.0935629 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90092895 |
Cholesteryl esters to total lipids ratio in medium HDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-33 |
33 |
rs10455872 |
0.0892728 |
cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS934194_H |
GCST90092915 |
Triglycerides to total lipids ratio in medium LDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-39 |
38.155 |
rs10455872 |
0.0976969 |
triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
GWAS934656_H |
GCST90092925 |
Phospholipids to total lipids ratio in medium VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-46 |
45.302 |
rs10455872 |
0.104626 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:35213538 |
GWAS935343_H |
GCST90092935 |
Ratio of omega-6 fatty acids to total fatty acids |
115,006 European ancestry individuals |
A |
0.921013 |
3E-79 |
78.523 |
rs10455872 |
0.138305 |
fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
GWAS936449_H |
GCST90092917 |
Cholesterol to total lipids ratio in medium VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
4E-92 |
91.398 |
rs10455872 |
0.146384 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
GWAS939002_H |
GCST90092953 |
Phospholipids to total lipids ratio in small HDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-15 |
14.523 |
rs10455872 |
0.0584181 |
phospholipids:total lipids ratio (EFO:0020946) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS939357_H |
GCST90092941 |
Ratio of polyunsaturated fatty acids to total fatty acids |
115,006 European ancestry individuals |
A |
0.921013 |
6E-72 |
71.222 |
rs10455872 |
0.131843 |
fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
None Available |
GCST90092945 |
Cholesterol to total lipids ratio in small HDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-51 |
51 |
rs10455872 |
0.113787 |
cholesterol:total lipids ratio (EFO:0020943) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS940370_H |
GCST90093002 |
Average diameter for VLDL particles |
115,082 European ancestry individuals |
A |
0.921013 |
2E-205 |
204.699 |
rs10455872 |
0.217921 |
very low density lipoprotein particle size measurement (EFO:0008594)
|
PMID:35213538 |
GWAS941403_H |
GCST90133362 |
Total omega-3 fatty acid levels |
114,999 European ancestry individuals |
A |
0.92 |
7E-17 |
16.155 |
rs10455872 |
0.063 |
omega-3 polyunsaturated fatty acid measurement (EFO:0010119)
|
PMID:35692035 |
None Available |
GCST90092947 |
Cholesteryl esters to total lipids ratio in small HDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-40 |
39.699 |
rs10455872 |
0.0994618 |
cholesteryl esters:total lipids ratio (EFO:0020944) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
None Available |
GCST90092921 |
Free cholesterol to total lipids ratio in medium VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-80 |
80 |
rs10455872 |
0.138417 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS945532_H |
GCST90092919 |
Cholesteryl esters to total lipids ratio in medium VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-93 |
92.523 |
rs10455872 |
0.146658 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
GWAS945972_H |
GCST90092940 |
Ratio of polyunsaturated fatty acids to monounsaturated fatty acids |
115,006 European ancestry individuals |
A |
0.921013 |
8E-75 |
74.097 |
rs10455872 |
0.134049 |
fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
GWAS956912_H |
GCST90093048 |
Phospholipid levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-233 |
233 |
rs10455872 |
0.23877 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639)
|
PMID:35213538 |
GWAS956979_H |
GCST90093045 |
Free cholesterol to total lipids ratio in chylomicrons and extremely large VLDL |
111,638 European ancestry individuals |
A |
0.922155 |
9E-265 |
264.046 |
rs10455872 |
0.266534 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS957243_H |
GCST90093051 |
Triglycerides to total lipids ratio in chylomicrons and extremely large VLDL |
111,638 European ancestry individuals |
A |
0.922155 |
9E-256 |
255.046 |
rs10455872 |
0.265252 |
chylomicron measurement (EFO:0008596) triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS957958_H |
GCST90093041 |
Cholesterol to total lipids ratio in chylomicrons and extremely large VLDL |
111,638 European ancestry individuals |
A |
0.922155 |
3E-283 |
282.523 |
rs10455872 |
0.277545 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
GWAS958199_H |
GCST90093050 |
Triglyceride levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-320 |
319.302 |
rs10455872 |
0.281537 |
chylomicron measurement (EFO:0008596) triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
None Available |
GCST90093039 |
Triglycerides to total lipids ratio in very small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-47 |
46.699 |
rs10455872 |
0.104574 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS958610_H |
GCST90093044 |
Free cholesterol levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
8E-231 |
230.097 |
rs10455872 |
0.238256 |
free cholesterol measurement (EFO:0008591) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS958672_H |
GCST90093040 |
Cholesterol levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-207 |
206.155 |
rs10455872 |
0.225713 |
chylomicron measurement (EFO:0008596) total cholesterol measurement (EFO:0004574) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS958879_H |
GCST90093046 |
Total lipid levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-277 |
276.302 |
rs10455872 |
0.261294 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529)
|
PMID:35213538 |
None Available |
GCST90092821 |
Glycoprotein acetyls levels |
115,082 European ancestry individuals |
A |
0.921013 |
1E-24 |
24 |
rs10455872 |
0.0776147 |
glycoprotein measurement (EFO:0004555)
|
PMID:35213538 |
GWAS962463_H |
GCST90092973 |
Free cholesterol to total lipids ratio in small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-58 |
57.523 |
rs10455872 |
0.116991 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS962834_H |
GCST90239655 |
Low density lipoprotein cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
9E-367 |
366.046 |
rs10455872 |
N/A |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34887591 |
GWAS964375_H |
GCST90092955 |
Triglycerides to total lipids ratio in small HDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-46 |
45.155 |
rs10455872 |
0.103095 |
triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS964467_H |
GCST90092961 |
Free cholesterol to total lipids ratio in small LDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-144 |
144 |
rs10455872 |
0.188662 |
low density lipoprotein cholesterol measurement (EFO:0004611) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS964521_H |
GCST90239667 |
Non-HDL cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
1E-220 |
220 |
rs10455872 |
N/A |
non-high density lipoprotein cholesterol measurement (EFO:0005689)
|
PMID:34887591 |
GWAS965093_H |
GCST90092965 |
Phospholipids to total lipids ratio in small LDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-87 |
86.155 |
rs10455872 |
0.15102 |
low density lipoprotein cholesterol measurement (EFO:0004611) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:35213538 |
GWAS965134_H |
GCST90092971 |
Cholesteryl esters to total lipids ratio in small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
4E-83 |
82.398 |
rs10455872 |
0.145663 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
GWAS965629_H |
GCST90239658 |
Low density lipoprotein cholesterol levels |
1,320,016 European ancestry individuals |
G |
0.0694387 |
4E-282 |
281.398 |
rs10455872 |
0.113763 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:34887591 |
GWAS966136_H |
GCST90092959 |
Cholesteryl esters to total lipids ratio in small LDL |
115,082 European ancestry individuals |
A |
0.921013 |
6E-87 |
86.222 |
rs10455872 |
0.151079 |
low density lipoprotein cholesterol measurement (EFO:0004611) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
GWAS966570_H |
GCST90092969 |
Cholesterol to total lipids ratio in small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-81 |
80.302 |
rs10455872 |
0.141595 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
GWAS968672_H |
GCST90092979 |
Triglycerides to total lipids ratio in small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-75 |
74.523 |
rs10455872 |
0.135512 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS969191_H |
GCST90092949 |
Free cholesterol to total lipids ratio in small HDL |
115,082 European ancestry individuals |
A |
0.921013 |
9E-19 |
18.046 |
rs10455872 |
0.0641434 |
free cholesterol:total lipids ratio (EFO:0020945) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS969328_H |
GCST90092977 |
Phospholipids to total lipids ratio in small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-55 |
55 |
rs10455872 |
0.114603 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipids:total lipids ratio (EFO:0020946)
|
PMID:35213538 |
GWAS971234_H |
GCST90093029 |
Cholesterol to total lipids ratio in very small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-43 |
42.302 |
rs10455872 |
0.0993442 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
None Available |
GCST90093020 |
Free cholesterol levels in very large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-130 |
129.523 |
rs10455872 |
0.17945 |
free cholesterol measurement (EFO:0008591) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS972475_H |
GCST90179149 |
Triglyceride levels (MTAG) |
361,194 European ancestry individuals |
A |
NR |
4E-14 |
13.398 |
rs10455872 |
0.034395 |
triglyceride measurement (EFO:0004530)
|
PMID:36376304 |
GWAS972620_H |
GCST90093024 |
Phospholipid levels in very large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
7E-139 |
138.155 |
rs10455872 |
0.18472 |
very low density lipoprotein cholesterol measurement (EFO:0008317) phospholipid measurement (EFO:0004639)
|
PMID:35213538 |
GWAS973257_H |
GCST90239676 |
Total cholesterol levels |
1,320,016 European ancestry individuals |
G |
0.0691377 |
5E-221 |
220.302 |
rs10455872 |
0.100603 |
total cholesterol measurement (EFO:0004574)
|
PMID:34887591 |
GWAS974158_H |
GCST90093023 |
Concentration of very large VLDL particles |
115,082 European ancestry individuals |
A |
0.921013 |
2E-132 |
131.699 |
rs10455872 |
0.179616 |
very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS974291_H |
GCST90093026 |
Triglyceride levels in very large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
5E-172 |
171.302 |
rs10455872 |
0.203992 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS975293_H |
GCST90092966 |
Triglyceride levels in small LDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-126 |
125.699 |
rs10455872 |
0.177161 |
triglyceride measurement (EFO:0004530) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
None Available |
GCST90093021 |
Free cholesterol to total lipids ratio in very large VLDL |
114,160 European ancestry individuals |
A |
0.921216 |
2E-95 |
94.699 |
rs10455872 |
0.15373 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS977161_H |
GCST90092967 |
Triglycerides to total lipids ratio in small LDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-127 |
126.699 |
rs10455872 |
0.176806 |
triglycerides:total lipids ratio (EFO:0020947) low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:35213538 |
GWAS977689_H |
GCST90092992 |
Total triglycerides levels |
115,082 European ancestry individuals |
A |
0.921013 |
5E-129 |
128.302 |
rs10455872 |
0.178066 |
triglyceride measurement (EFO:0004530)
|
PMID:35213538 |
GWAS978313_H |
GCST90239670 |
Non-HDL cholesterol levels |
1,320,016 European ancestry individuals |
G |
0.0694945 |
3E-169 |
168.523 |
rs10455872 |
0.104949 |
non-high density lipoprotein cholesterol measurement (EFO:0005689)
|
PMID:34887591 |
GWAS978702_H |
GCST90092994 |
Degree of unsaturation |
115,006 European ancestry individuals |
A |
0.921013 |
8E-43 |
42.097 |
rs10455872 |
0.0996016 |
fatty acid measurement (EFO:0005110)
|
PMID:35213538 |
GWAS978803_H |
GCST90092983 |
Ratio of triglycerides to phosphoglycerides |
115,006 European ancestry individuals |
A |
0.921013 |
7E-130 |
129.155 |
rs10455872 |
0.171823 |
triglyceride measurement (EFO:0004530) phospholipid measurement (EFO:0004639)
|
PMID:35213538 |
GWAS980175_H |
GCST90093022 |
Total lipid levels in very large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
4E-147 |
146.398 |
rs10455872 |
0.189654 |
very low density lipoprotein cholesterol measurement (EFO:0008317) lipid measurement (EFO:0004529)
|
PMID:35213538 |
None Available |
GCST90093031 |
Cholesteryl esters to total lipids ratio in very small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-41 |
40.523 |
rs10455872 |
0.0965085 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
GWAS980811_H |
GCST90093017 |
Cholesterol to total lipids ratio in very large VLDL |
114,160 European ancestry individuals |
A |
0.921216 |
8E-207 |
206.097 |
rs10455872 |
0.224507 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesterol:total lipids ratio (EFO:0020943)
|
PMID:35213538 |
GWAS982408_H |
GCST90093027 |
Triglycerides to total lipids ratio in very large VLDL |
114,160 European ancestry individuals |
A |
0.921216 |
8E-164 |
163.097 |
rs10455872 |
0.202108 |
triglycerides:total lipids ratio (EFO:0020947) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS982441_H |
GCST90093015 |
Triglycerides to total lipids ratio in very large HDL |
115,056 European ancestry individuals |
A |
0.921012 |
2E-42 |
41.699 |
rs10455872 |
0.0979869 |
triglycerides:total lipids ratio (EFO:0020947) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS982733_H |
GCST90093019 |
Cholesteryl esters to total lipids ratio in very large VLDL |
114,160 European ancestry individuals |
A |
0.921216 |
6E-225 |
224.222 |
rs10455872 |
0.234177 |
very low density lipoprotein cholesterol measurement (EFO:0008317) cholesteryl esters:total lipids ratio (EFO:0020944)
|
PMID:35213538 |
None Available |
GCST90093033 |
Free cholesterol to total lipids ratio in very small VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
2E-31 |
30.699 |
rs10455872 |
0.0886495 |
very low density lipoprotein cholesterol measurement (EFO:0008317) free cholesterol:total lipids ratio (EFO:0020945)
|
PMID:35213538 |
GWAS987461_H |
GCST90093047 |
Concentration of chylomicrons and extremely large VLDL particles |
115,082 European ancestry individuals |
A |
0.921013 |
1E-239 |
239 |
rs10455872 |
0.242419 |
chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
GWAS989553_H |
GCST90093042 |
Cholesteryl ester levels in chylomicrons and extremely large VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
4E-184 |
183.398 |
rs10455872 |
0.21335 |
cholesteryl ester measurement (EFO:0010351) chylomicron measurement (EFO:0008596) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |
None Available |
GCST90093014 |
Triglyceride levels in very large HDL |
115,082 European ancestry individuals |
A |
0.921013 |
3E-71 |
70.523 |
rs10455872 |
0.133011 |
triglyceride measurement (EFO:0004530) high density lipoprotein cholesterol measurement (EFO:0004612)
|
PMID:35213538 |
GWAS994320_H |
GCST90093003 |
Triglyceride levels in VLDL |
115,082 European ancestry individuals |
A |
0.921013 |
1E-154 |
154 |
rs10455872 |
0.194336 |
triglyceride measurement (EFO:0004530) very low density lipoprotein cholesterol measurement (EFO:0008317)
|
PMID:35213538 |