GWAS651747_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS651747_H (eosinophil percentage of leukocytes QTL GWAS651747 (human)) Homo sapiens

Symbol: GWAS651747_H
Name: eosinophil percentage of leukocytes QTL GWAS651747 (human)
RGD ID: 407002771
Trait: eosinophil quantity   (VT:0002602)    
Measurement Type: blood eosinophil count to total leukocyte count ratio   (CMO:0000369)    
LOD Score: Not Available
P Value: 2E-307
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812111,494,996 - 111,494,997RGD_MAPPER_PIPELINEGRCh38
GRCh3712111,932,800 - 111,932,801RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS651747_HHumanblood eosinophil count to total leukocyte count ratio  IAGPrs7137828405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS651747_HHumaneosinophil quantity  IAGPrs7137828405850206Based on the EFO term IDGWAS_CATALOGPMID:32888494

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS651747_HHumaneosinophil percentage of leukocytes  IAGPrs7137828405850206 GWAS_CATALOGPMID:32888494

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1347160ATXN2ataxin 212111452214111599673Human


Peak: (rs7137828)
Human AssemblyChrPosition (strand)Source
GRCh3812111,494,996 - 111,494,997RGD_MAPPER_PIPELINE


1 to 10 of 75 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597289880GWAS1385954_Hfree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement QTL GWAS1385954 (human)2e-14free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)12111494996111494997Human
1298449UAE2_HUrinary albumin excretion QTL 2 (human)20.005Urinary albumin excretionurine albumin:creatinine ratio (ACR)12102836889128836889Human
597163026GWAS1259100_Hfactor XI measurement, coronary artery disease QTL GWAS1259100 (human)1e-21factor XI measurement, coronary artery disease12111494996111494997Human
406899526GWAS548502_Hsystolic blood pressure QTL GWAS548502 (human)3e-23systolic blood pressuresystolic blood pressure (CMO:0000004)12111494996111494997Human
597594517GWAS1651377_Heosinophil count QTL GWAS1651377 (human)1e-184eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)12111494996111494997Human
407002446GWAS651422_Hhematocrit QTL GWAS651422 (human)1e-241hematocrithematocrit (CMO:0000037)12111494996111494997Human
597066139GWAS1162213_Hsystemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis QTL GWAS1162213 (human)2e-09open-angle glaucoma12111494996111494997Human
597038104GWAS1134178_Hparental longevity QTL GWAS1134178 (human)3e-12total life span (VT:0001661)12111494996111494997Human
597054854GWAS1150928_Hsystolic blood pressure QTL GWAS1150928 (human)9e-56systolic blood pressuresystolic blood pressure (CMO:0000004)12111494996111494997Human
597601546GWAS1658406_Hbody mass index QTL GWAS1658406 (human)8e-19body mass indexbody mass index (BMI) (CMO:0000105)12111494996111494997Human

1 to 10 of 75 rows


1 to 20 of 85 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS651747_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals T 0.51759 2E-307 306.699 rs7137828 0.08334227 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS543244_H GCST007095 Systolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals C NR 0.000003 5.523 rs7137828 0.266 systolic blood pressure (EFO:0006335)
 PMID:27841878
GWAS548157_H GCST007098 Diastolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals C NR 4E-18 17.398 rs7137828 0.32 diastolic blood pressure (EFO:0006336)
 PMID:27841878
GWAS548165_H GCST007098 Diastolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals C NR 7E-15 14.155 rs7137828 0.304 diastolic blood pressure (EFO:0006336)
 PMID:27841878
GWAS548169_H GCST007098 Diastolic blood pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals C NR 0.000004 5.398 rs7137828 0.613 diastolic blood pressure (EFO:0006336)
 PMID:27841878
GWAS548502_H GCST007099 Systolic blood pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals C NR 3E-23 22.523 rs7137828 0.389 systolic blood pressure (EFO:0006335)
 PMID:27841878
GWAS1635417_H GCST90479629 hematocrit (mean, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,852 European ancestry individuals C 0.3906 1E-47 47 rs7137828 0.04163 hematocrit (EFO:0004348)
 PMID:39024449
GWAS551146_H GCST007094 Diastolic blood pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals C NR 1E-63 63 rs7137828 0.403 diastolic blood pressure (EFO:0006336)
 PMID:27841878
GWAS1636701_H GCST90479606 eosinophil (fraction, minimum, inv-norm transformed) 98,055 African American or Afro-Caribbean individuals, 47,410 Hispanic or Latin American individuals, 4,652 East Asian ancestry individuals, 335,542 European ancestry individuals C 0.3887 3E-101 100.523 rs7137828 0.06236 eosinophil count (EFO:0004842)
 PMID:39024449
GWAS1636713_H GCST90479630 hematocrit (minimum, inv-norm transformed) 114,988 African American or Afro-Caribbean individuals, 55,841 Hispanic or Latin American individuals, 5,964 East Asian ancestry individuals, 407,854 European ancestry individuals C 0.3906 4E-24 23.398 rs7137828 0.02735 hematocrit (EFO:0004348)
 PMID:39024449
GWAS1637568_H GCST90479665 lymphocyte (absolute count, minimum, inv-norm transformed) 70,597 African American or Afro-Caribbean individuals, 36,547 Hispanic or Latin American individuals, 3,839 East Asian ancestry individuals, 253,480 European ancestry individuals C 0.3917 2E-92 91.699 rs7137828 0.06473 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1637867_H GCST90479664 lymphocyte (absolute count, mean, inv-norm transformed) 70,580 African American or Afro-Caribbean individuals, 36,536 Hispanic or Latin American individuals, 3,839 East Asian ancestry individuals, 253,317 European ancestry individuals C 0.3916 1E-160 160 rs7137828 0.09473 lymphocyte count (EFO:0004587)
 PMID:39024449
GWAS1120967_H GCST005038 Allergic disease (asthma, hay fever or eczema) 180,129 European ancestry cases, 180,709 European ancestry controls T 0.54 2E-10 9.699 rs7137828 1.033 PMID:29083406
GWAS1642181_H GCST90479602 eosinophil (absolute count, mean, inv-norm transformed) 90,448 African American or Afro-Caribbean individuals, 42,397 Hispanic or Latin American individuals, 3,996 East Asian ancestry individuals, 310,757 European ancestry individuals C 0.3897 4E-284 283.398 rs7137828 0.1257 eosinophil count (EFO:0004842)
 PMID:39024449
GWAS1704825_H GCST011100 Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) at least 837,415 European ancestry individuals T 0.5167 5E-12 11.302 rs7137828 N/A healthspan (EFO:0009762)
parental longevity (EFO:0007796)
life span trait (OBA:VT0005372)
 PMID:32678081
GWAS1642986_H GCST90479604 eosinophil (fraction, maximum, inv-norm transformed) 98,055 African American or Afro-Caribbean individuals, 47,410 Hispanic or Latin American individuals, 4,652 East Asian ancestry individuals, 335,542 European ancestry individuals C 0.3887 3E-168 167.523 rs7137828 0.08901 eosinophil count (EFO:0004842)
 PMID:39024449
GWAS1643585_H GCST90475539 neutrophil (fraction, minimum, inv-norm transformed) 38,543 Hispanic or Latin American individuals C 0.3061 2E-16 15.699 rs7137828 0.06346 neutrophil count (EFO:0004833)
 PMID:39024449
GWAS1124690_H GCST006167 Mean arterial pressure x alcohol consumption interaction (2df test) 91,110 European ancestry drinkers and non-drinkers, 21,416 African American or Afro-Caribbean drinkers and non-drinkers, 12,365 Asian ancestry drinkers and non-drinkers, 8,470 Hispanic or Latin American drinkers and non-drinkers T 0.53 2E-19 18.699 rs7137828 N/A mean arterial pressure (EFO:0006340)
alcohol drinking (EFO:0004329)
 PMID:29912962
GWAS1643803_H GCST90479601 eosinophil (absolute count, maximum, inv-norm transformed) 90,403 African American or Afro-Caribbean individuals, 42,380 Hispanic or Latin American individuals, 3,995 East Asian ancestry individuals, 310,588 European ancestry individuals C 0.3897 9E-227 226.046 rs7137828 0.1086 eosinophil count (EFO:0004842)
 PMID:39024449
GWAS1644432_H GCST90479603 eosinophil (absolute count, minimum, inv-norm transformed) 90,479 African American or Afro-Caribbean individuals, 42,403 Hispanic or Latin American individuals, 3,997 East Asian ancestry individuals, 310,849 European ancestry individuals C 0.3897 5E-159 158.302 rs7137828 0.07774 eosinophil count (EFO:0004842)
 PMID:39024449
1 to 20 of 85 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST90002382 GWAS Catalog

Note Type Note Reference