GWAS641955_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS641955_H (sex hormone-binding globulin measurement QTL GWAS641955 (human)) Homo sapiens

Symbol: GWAS641955_H
Name: sex hormone-binding globulin measurement QTL GWAS641955 (human)
RGD ID: 406992979
Trait: sex hormone-binding globulin measurement
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381540,095,527 - 40,095,528RGD_MAPPER_PIPELINEGRCh38
GRCh371540,387,728 - 40,387,729RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS641955_HHumansex hormone-binding globulin measurement  IAGPrs11637595405850206 GWAS_CATALOGPMID:32042192
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1342866BMFBcl2 modifying factor154008789040108879Human

Position Markers

Peak: (rs11637595)
Human AssemblyChrPosition (strand)Source
GRCh381540,095,527 - 40,095,528RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407267911GWAS916887_Hsex hormone-binding globulin measurement QTL GWAS916887 (human)5e-14sex hormone-binding globulin measurement154009552740095528Human
407241892GWAS890868_Hsex hormone-binding globulin measurement QTL GWAS890868 (human)2e-09sex hormone-binding globulin measurement154009552740095528Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407197217GWAS846193_Hsex hormone-binding globulin measurement QTL GWAS846193 (human)4e-14sex hormone-binding globulin measurement154009552740095528Human
407029060GWAS678036_Hsex hormone-binding globulin measurement QTL GWAS678036 (human)3e-14sex hormone-binding globulin measurement154009552740095528Human
406996389GWAS645365_Hsex hormone-binding globulin measurement QTL GWAS645365 (human)2e-18sex hormone-binding globulin measurement154009552740095528Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
406992979GWAS641955_Hsex hormone-binding globulin measurement QTL GWAS641955 (human)1e-08sex hormone-binding globulin measurement154009552740095528Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS641955_H GCST90012107 Sex hormone-binding globulin levels 189,473 European ancestry women C 0.723599 1E-8 8 rs11637595 0.00915883 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS645365_H GCST90012106 Sex hormone-binding globulin levels adjusted for BMI 188,908 European ancestry women C 0.723599 2E-18 17.699 rs11637595 0.0119621 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS678036_H GCST90239822 Sex hormone-binding globulin levels 188,443 British ancestry women ? NR 3E-14 13.523 rs11637595 0.0261288 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:36653534
GWAS846193_H GCST90104297 Sex hormone-binding globulin levels 4,522 African ancestry individuals, 196,901 European ancestry individuals ? NR 4E-14 13.398 rs11637595 7.577 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS890868_H GCST90104277 Sex hormone-binding globulin levels in postmenopausal women 92,911 European ancestry individuals T 0.271954 2E-9 8.699 rs11637595 0.0317844 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS916887_H GCST90104273 Sex hormone-binding globulin levels 196,901 European ancestry individuals T 0.271954 5E-14 13.302 rs11637595 0.0272021 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
None Available GCST90444202 Type 2 diabetes 51,256 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry cases, 370,487 African, African American, East Asian, South Asian, European, Middle Eastern, admixed American, other or other admixed ancestry controls C 0.736682 2E-9 8.699 rs11637595 0.0538 PMID:39379762
Database Acc Id Source(s)
GWAS Catalog GCST90012107 GWAS Catalog

RGD Curation Notes
Note Type Note Reference