GWAS640234_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS640234_H (systolic blood pressure QTL GWAS640234 (human)) Homo sapiens

Symbol: GWAS640234_H
Name: systolic blood pressure QTL GWAS640234 (human)
RGD ID: 406991258
Trait: systolic blood pressure
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 3.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3811,344,634 - 1,344,635RGD_MAPPER_PIPELINEGRCh38
GRCh3711,280,014 - 1,280,015RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS640234_HHumansystolic blood pressure  IAGPrs307359405850206Based on the EFO term IDGWAS_CATALOGPMID:30595370

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS640234_HHumansystolic blood pressure  IAGPrs307359405850206 GWAS_CATALOGPMID:30595370
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
733042DVL1dishevelled segment polarity protein 1113352781349418Human

Position Markers

Peak: (rs307359)
Human AssemblyChrPosition (strand)Source
GRCh3811,344,634 - 1,344,635RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407415593GWAS1064569_Hpulse pressure measurement QTL GWAS1064569 (human)2e-13pulse pressure measurementpulse pressure (CMO:0000292)113446341344635Human
407397344GWAS1046320_Hsystolic blood pressure QTL GWAS1046320 (human)0.0000003systolic blood pressuresystolic blood pressure (CMO:0000004)113446341344635Human
406991258GWAS640234_Hsystolic blood pressure QTL GWAS640234 (human)3e-11systolic blood pressuresystolic blood pressure (CMO:0000004)113446341344635Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS640234_H GCST007087 Systolic blood pressure approximately 422,000 European ancestry individuals ? NR 3E-11 10.523 rs307359 N/A systolic blood pressure (EFO:0006335)
 PMID:30595370
GWAS1046320_H GCST90310294 Systolic blood pressure 1,028,980 European ancestry individuals G NR 3E-7 6.523 rs307359 0.2613 systolic blood pressure (EFO:0006335)
 PMID:38689001
GWAS1064569_H GCST90310296 Pulse pressure 1,028,980 European ancestry individuals G NR 2E-13 12.699 rs307359 0.2674 pulse pressure measurement (EFO:0005763)
 PMID:38689001
Database Acc Id Source(s)
GWAS Catalog GCST007087 GWAS Catalog

RGD Curation Notes
Note Type Note Reference