GWAS636701_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS636701_H (Thyroid preparation use measurement QTL GWAS636701 (human)) Homo sapiens

Symbol: GWAS636701_H
Name: Thyroid preparation use measurement QTL GWAS636701 (human)
RGD ID: 406987725
Trait: Thyroid preparation use measurement
LOD Score: Not Available
P Value: 1.0E-10
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38577,247,778 - 77,247,779RGD_MAPPER_PIPELINEGRCh38
GRCh37576,543,603 - 76,543,604RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS636701_HHumanThyroid preparation use measurement  IAGPrs10036386405850206 GWAS_CATALOGPMID:34594039
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348334PDE8Bphosphodiesterase 8B57708671577428256Human

Position Markers

Peak: (rs10036386)
Human AssemblyChrPosition (strand)Source
GRCh38577,247,778 - 77,247,779RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406962594GWAS611570_Hhypothyroidism QTL GWAS611570 (human)5e-13hypothyroidism57724777877247779Human
406976703GWAS625679_HThyroid preparation use measurement QTL GWAS625679 (human)6e-12Thyroid preparation use measurement57724777877247779Human
406987725GWAS636701_HThyroid preparation use measurement QTL GWAS636701 (human)1e-10Thyroid preparation use measurement57724777877247779Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
None Available GCST007932 Medication use (thyroid preparations) 24,832 European ancestry cases, 280,750 European ancestry controls T 0.381268 6E-12 11.222 rs10036386 0.06467282 Thyroid preparation use measurement (EFO:0009933)
 PMID:31015401
None Available GCST007073 Hypothyroidism approximately 459,000 European ancestry individuals ? NR 5E-13 12.302 rs10036386 N/A hypothyroidism (EFO:0004705)
 PMID:30595370
None Available GCST90018990 Medication use (thyroid preparations) 24,832 European ancestry cases, 280,750 European ancestry controls, 3,103 East Asian ancestry cases, 175,623 East Asian ancestry controls T NR 1E-10 10 rs10036386 0.058 Thyroid preparation use measurement (EFO:0009933)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90018990 GWAS Catalog

RGD Curation Notes
Note Type Note Reference