GWAS634275_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS634275_H (diffuse large B-cell lymphoma, rheumatoid arthritis QTL GWAS634275 (human)) Homo sapiens

Symbol: GWAS634275_H
Name: diffuse large B-cell lymphoma, rheumatoid arthritis QTL GWAS634275 (human)
RGD ID: 406985299
Trait: diffuse large B-cell lymphoma, rheumatoid arthritis
LOD Score: Not Available
P Value: 2.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3812,622,185 - 2,622,186RGD_MAPPER_PIPELINEGRCh38
GRCh3712,553,624 - 2,553,625RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1603610MMEL1membrane metalloendopeptidase like 1125906392633016Human

Position Markers

Peak: (rs3890745)
Human AssemblyChrPosition (strand)Source
GRCh3812,622,185 - 2,622,186RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407006370GWAS655346_Hrheumatoid arthritis QTL GWAS655346 (human)0.0000001rheumatoid arthritis126221852622186Human
406985299GWAS634275_Hdiffuse large B-cell lymphoma, rheumatoid arthritis QTL GWAS634275 (human)2e-08diffuse large B-cell lymphoma, rheumatoid arthritis126221852622186Human
406967221GWAS616197_Hrheumatoid arthritis QTL GWAS616197 (human)0.000004rheumatoid arthritis126221852622186Human
406966170GWAS615146_Hrheumatoid arthritis QTL GWAS615146 (human)0.000001rheumatoid arthritis126221852622186Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS615146_H GCST002323 Rheumatoid arthritis 3,034 European ancestry cases, 5,271 European ancestry controls ? NR 0.000001 6 rs3890745 1.18 rheumatoid arthritis (EFO:0000685)
 PMID:24449572
GWAS616197_H GCST000679 Rheumatoid arthritis 5,539 European ancestry cases, 20,169 European ancestry controls T 0.68 0.000004 5.398 rs3890745 1.12 rheumatoid arthritis (EFO:0000685)
 PMID:20453842
GWAS634275_H GCST008725 Diffuse large B-cell lymphoma or rheumatoid arthritis 3,617 European ancestry diffuse large B-cell lymphoma cases, 3,921 European ancestry rheumatoid arthritis cases, 11,516 European ancestry controls ? NR 2E-8 7.699 rs3890745 1.1441647 diffuse large B-cell lymphoma (EFO:0000403)
rheumatoid arthritis (EFO:0000685)
 PMID:31407831
GWAS655346_H GCST000232 Rheumatoid arthritis 3,393 European ancestry cases, 12,460 European ancestry controls T 0.67 1E-7 7 rs3890745 1.12 rheumatoid arthritis (EFO:0000685)
 PMID:18794853
Database Acc Id Source(s)
GWAS Catalog GCST008725 GWAS Catalog

RGD Curation Notes
Note Type Note Reference