GWAS630258_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS630258_H (serum metabolite measurement QTL GWAS630258 (human)) Homo sapiens

Symbol: GWAS630258_H
Name: serum metabolite measurement QTL GWAS630258 (human)
RGD ID: 406981282
Trait: serum metabolite measurement
LOD Score: Not Available
P Value: 2E-85
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381558,387,469 - 58,387,470RGD_MAPPER_PIPELINEGRCh38
GRCh371558,679,668 - 58,679,669RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS630258_HHumanserum metabolite measurement  IAGPrs7350789405850206 GWAS_CATALOGPMID:31636271
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs7350789)
Human AssemblyChrPosition (strand)Source
GRCh381558,387,469 - 58,387,470RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406938309GWAS587285_Htotal cholesterol measurement QTL GWAS587285 (human)0.0000003total cholesterol measurementblood total cholesterol level (CMO:0000051)155838746958387470Human
406984260GWAS633236_Hlevel of Sphingomyelin (d34:1) in blood serum QTL GWAS633236 (human)7e-11level of Sphingomyelin (d34:1) in blood serum155838746958387470Human
406938310GWAS587286_Htotal cholesterol measurement QTL GWAS587286 (human)2e-28total cholesterol measurementblood total cholesterol level (CMO:0000051)155838746958387470Human
406952910GWAS601886_Htotal cholesterol measurement QTL GWAS601886 (human)4e-78total cholesterol measurementblood total cholesterol level (CMO:0000051)155838746958387470Human
407102032GWAS751008_H1-linoleoyl-GPE (18:2) measurement QTL GWAS751008 (human)5e-181-linoleoyl-GPE (18:2) measurement155838746958387470Human
406962517GWAS611493_Hserum metabolite measurement QTL GWAS611493 (human)6e-28serum metabolite measurement155838746958387470Human
406952149GWAS601125_Hhigh density lipoprotein cholesterol measurement QTL GWAS601125 (human)4e-16high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838746958387470Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406903637GWAS552613_H1-docosahexaenoyl-GPE (22:6) measurement QTL GWAS552613 (human)2e-201-docosahexaenoyl-GPE (22:6) measurement155838746958387470Human
406952148GWAS601124_Hhigh density lipoprotein cholesterol measurement QTL GWAS601124 (human)0.0000001high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838746958387470Human
406952151GWAS601127_Hhigh density lipoprotein cholesterol measurement QTL GWAS601127 (human)3e-124high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838746958387470Human
406962518GWAS611494_Hserum metabolite measurement QTL GWAS611494 (human)1e-27serum metabolite measurement155838746958387470Human
406952150GWAS601126_Hhigh density lipoprotein cholesterol measurement QTL GWAS601126 (human)0.000004high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838746958387470Human
406968281GWAS617257_Hvery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio QTL GWAS617257 (human)2e-192very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)155838746958387470Human
406968280GWAS617256_Htriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement QTL GWAS617256 (human)1e-248triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurementblood very low density lipoprotein cholesterol level (CMO:0000648)155838746958387470Human
406980958GWAS629934_Hserum metabolite measurement QTL GWAS629934 (human)1e-47serum metabolite measurement155838746958387470Human
406980966GWAS629942_Hserum metabolite measurement QTL GWAS629942 (human)3e-13serum metabolite measurement155838746958387470Human
406938853GWAS587829_Htriglyceride measurement QTL GWAS587829 (human)0.000003triglyceride measurementblood triglyceride level (CMO:0000118)155838746958387470Human
406938852GWAS587828_Htriglyceride measurement QTL GWAS587828 (human)4e-13triglyceride measurementblood triglyceride level (CMO:0000118)155838746958387470Human
406980970GWAS629946_Hserum metabolite measurement QTL GWAS629946 (human)1e-12serum metabolite measurement155838746958387470Human
406938856GWAS587832_Htriglyceride measurement QTL GWAS587832 (human)2e-18triglyceride measurementblood triglyceride level (CMO:0000118)155838746958387470Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407101681GWAS750657_H1-arachidonoyl-GPE (20:4n6) measurement QTL GWAS750657 (human)2e-271-arachidonoyl-GPE (20:4n6) measurement155838746958387470Human
406984183GWAS633159_Hlevel of Phosphatidylcholine (17:0_18:1) in blood serum QTL GWAS633159 (human)4e-11level of Phosphatidylcholine (17:0_18:1) in blood serum155838746958387470Human
406981115GWAS630091_Hserum metabolite measurement QTL GWAS630091 (human)5e-11serum metabolite measurement155838746958387470Human
406979960GWAS628936_Hhematocrit QTL GWAS628936 (human)1e-13hematocrithematocrit (CMO:0000037)155838746958387470Human
406961661GWAS610637_Hserum metabolite measurement QTL GWAS610637 (human)4e-30serum metabolite measurement155838746958387470Human
406961660GWAS610636_Hserum metabolite measurement QTL GWAS610636 (human)8e-35serum metabolite measurement155838746958387470Human
406962052GWAS611028_Hsphingomyelin measurement QTL GWAS611028 (human)2e-12sphingomyelin measurement155838746958387470Human
406938502GWAS587478_Htotal cholesterol measurement QTL GWAS587478 (human)4e-22total cholesterol measurementblood total cholesterol level (CMO:0000051)155838746958387470Human
406961677GWAS610653_Hserum metabolite measurement QTL GWAS610653 (human)4e-19serum metabolite measurement155838746958387470Human
406961679GWAS610655_Hserum metabolite measurement QTL GWAS610655 (human)3e-18serum metabolite measurement155838746958387470Human
406962447GWAS611423_Hserum metabolite measurement QTL GWAS611423 (human)3e-12serum metabolite measurement155838746958387470Human
406961681GWAS610657_Hserum metabolite measurement QTL GWAS610657 (human)1e-10serum metabolite measurement155838746958387470Human
406961041GWAS610017_Hserum metabolite measurement QTL GWAS610017 (human)1e-25serum metabolite measurement155838746958387470Human
407096980GWAS745956_Htriglycerides to total lipids in large VLDL percentage QTL GWAS745956 (human)8e-196triglycerides to total lipids in large VLDL percentage 155838746958387470Human
406968730GWAS617706_Hvery low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio QTL GWAS617706 (human)5e-99very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratioblood very low density lipoprotein cholesterol level (CMO:0000648)155838746958387470Human
406961050GWAS610026_Hserum metabolite measurement QTL GWAS610026 (human)7e-32serum metabolite measurement155838746958387470Human
406981282GWAS630258_Hserum metabolite measurement QTL GWAS630258 (human)2e-85serum metabolite measurement155838746958387470Human
406981414GWAS630390_Hserum metabolite measurement QTL GWAS630390 (human)2e-10serum metabolite measurement155838746958387470Human
406961830GWAS610806_Hfree cholesterol measurement, intermediate density lipoprotein measurement QTL GWAS610806 (human)9e-11free cholesterol measurement, intermediate density lipoprotein measurementblood intermediate density lipoprotein cholesterol level (CMO:0001562)155838746958387470Human
406952874GWAS601850_Hphosphatidylethanolamine measurement QTL GWAS601850 (human)4e-20phosphatidylethanolamine measurement155838746958387470Human
406952115GWAS601091_Hhigh density lipoprotein cholesterol measurement QTL GWAS601091 (human)6e-100high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)155838746958387470Human
406981424GWAS630400_Hserum metabolite measurement QTL GWAS630400 (human)0.0000004serum metabolite measurement155838746958387470Human
406981425GWAS630401_Hserum metabolite measurement QTL GWAS630401 (human)0.0000005serum metabolite measurement155838746958387470Human
406960567GWAS609543_Hserum metabolite measurement QTL GWAS609543 (human)2e-11serum metabolite measurement155838746958387470Human
406981556GWAS630532_Hserum metabolite measurement QTL GWAS630532 (human)8e-10serum metabolite measurement155838746958387470Human
406981557GWAS630533_Hserum metabolite measurement QTL GWAS630533 (human)9e-10serum metabolite measurement155838746958387470Human
406982453GWAS631429_Htriglyceride measurement QTL GWAS631429 (human)5e-08triglyceride measurementblood triglyceride level (CMO:0000118)155838746958387470Human
406960568GWAS609544_Hserum metabolite measurement QTL GWAS609544 (human)2e-14serum metabolite measurement155838746958387470Human
406980792GWAS629768_Htriglyceride measurement, physical activity QTL GWAS629768 (human)1e-149triglyceride measurement, physical activityblood triglyceride level (CMO:0000118)155838746958387470Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS552613_H GCST90102681 1-docosahexaenoyl-GPE (22:6) levels 8,809 European ancestry individuals A NR 2E-20 19.699 rs7350789 0.141 1-docosahexaenoyl-GPE (22:6) measurement (EFO:0800296)
PMID:35050183
GWAS587285_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.64 3E-7 6.523 rs7350789 0.085 total cholesterol measurement (EFO:0004574)
PMID:29507422
GWAS587286_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-28 27.699 rs7350789 0.049 total cholesterol measurement (EFO:0004574)
PMID:29507422
GWAS587478_H GCST007143 Total cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.654 4E-22 21.398 rs7350789 0.047 total cholesterol measurement (EFO:0004574)
PMID:29507422
GWAS587828_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.654 4E-13 12.398 rs7350789 0.032 triglyceride measurement (EFO:0004530)
PMID:29507422
GWAS587829_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.64 0.000003 5.523 rs7350789 0.071 triglyceride measurement (EFO:0004530)
PMID:29507422
GWAS587832_H GCST007142 Triglycerides 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 2E-18 17.699 rs7350789 0.035 triglyceride measurement (EFO:0004530)
PMID:29507422
GWAS601091_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.654 6E-100 99.222 rs7350789 0.084 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:29507422
GWAS601124_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.676 1E-7 7 rs7350789 0.071 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:29507422
GWAS601125_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.64 4E-16 15.398 rs7350789 0.113 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:29507422
GWAS601126_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G 0.628 0.000004 5.398 rs7350789 0.104 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:29507422
GWAS601127_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals G NR 3E-124 123.523 rs7350789 0.085 high density lipoprotein cholesterol measurement (EFO:0004612)
PMID:29507422
GWAS601850_H GCST008929 Phosphatidylethanolamine levels 2,045 European ancestry individuals A NR 4E-20 19.398 rs7350789 0.2979 phosphatidylethanolamine measurement (EFO:0010228)
PMID:31551469
GWAS601886_H GCST006614 Total cholesterol levels 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals A 0.3451 4E-78 77.398 rs7350789 0.0522 total cholesterol measurement (EFO:0004574)
PMID:30275531
GWAS609543_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-11 10.699 rs7350789 0.054938268 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS609544_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-14 13.699 rs7350789 0.0702734 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610017_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-25 25 rs7350789 0.11972121 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610026_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 7E-32 31.155 rs7350789 0.10872544 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610636_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 8E-35 34.097 rs7350789 0.10312867 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610637_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 4E-30 29.398 rs7350789 0.09544789 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610653_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 4E-19 18.398 rs7350789 0.13139343 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610655_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 3E-18 17.523 rs7350789 0.109545276 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS610657_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 1E-10 10 rs7350789 0.09513239 serum metabolite measurement (EFO:0005653)
PMID:31636271
None Available GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 2E-11 10.699 rs7350789 0.08209028 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS611423_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 3E-12 11.523 rs7350789 0.08568997 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS611493_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 6E-28 27.222 rs7350789 0.09362299 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS611494_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 1E-27 27 rs7350789 0.08421296 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS617256_H GCST90092879 Triglycerides to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 1E-248 248 rs7350789 0.144797 triglycerides:total lipids ratio (EFO:0020947)
very low density lipoprotein cholesterol measurement (EFO:0008317)
PMID:35213538
GWAS617257_H GCST90092877 Phospholipids to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 2E-192 191.699 rs7350789 0.124104 very low density lipoprotein cholesterol measurement (EFO:0008317)
phospholipids:total lipids ratio (EFO:0020946)
PMID:35213538
GWAS617706_H GCST90092873 Free cholesterol to total lipids ratio in large VLDL 115,071 European ancestry individuals G 0.646053 5E-99 98.302 rs7350789 0.0904029 very low density lipoprotein cholesterol measurement (EFO:0008317)
free cholesterol:total lipids ratio (EFO:0020945)
PMID:35213538
GWAS628936_H GCST90002383 Hematocrit 408,112 British individuals A 0.354791 1E-13 13 rs7350789 0.017170137 hematocrit (EFO:0004348)
PMID:32888494
GWAS629768_H GCST007286 Triglycerides x physical activity interaction (2df test) 7,294 African American inactive individuals, 12,832 African American active individuals, 1,352 Asian ancestry inactive individuals, 3,049 Asian ancestry active individuals, 20,622 European ancestry inactive individuals, 51,480 European ancestry active individuals, 2,166 Hispanic or Latin American inactive individuals, 3,486 Hispanic or Latin American active individuals A 0.346 1E-149 149 rs7350789 N/A triglyceride measurement (EFO:0004530)
physical activity (EFO:0003940)
PMID:30670697
GWAS629934_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 1E-47 47 rs7350789 0.18179038 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS629942_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 3E-13 12.523 rs7350789 0.09118287 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS629946_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 1E-12 12 rs7350789 0.08727236 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630091_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 5E-11 10.302 rs7350789 0.057159528 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630258_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-85 84.699 rs7350789 0.1738073 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630390_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 2E-10 9.699 rs7350789 0.0665491 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630400_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 4E-7 6.398 rs7350789 0.064160354 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630401_H GCST009242 Serum metabolite levels 6,263 Finnish ancestry men ? NR 5E-7 6.302 rs7350789 0.061311882 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630532_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 8E-10 9.097 rs7350789 0.06674564 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS630533_H GCST009240 Serum metabolite levels (CMS) 6,263 Finnish ancestry men ? NR 9E-10 9.046 rs7350789 0.05438878 serum metabolite measurement (EFO:0005653)
PMID:31636271
GWAS631429_H GCST011050 Postprandial triglyceride response 5,630 individuals A 0.36 5E-8 7.302 rs7350789 0.11 triglyceride measurement (EFO:0004530)
PMID:32603185
GWAS633159_H GCST90277296 Phosphatidylcholine (17:0_18:1) levels 7,073 Finnish ancestry individuals A 0.39282 4E-11 10.398 rs7350789 0.112631 PMID:37907536
GWAS633236_H GCST90277370 Sphingomyelin (d34:1) levels 7,174 Finnish ancestry individuals A 0.39282 7E-11 10.155 rs7350789 0.110435 PMID:37907536
GWAS745956_H GCST90269690 Triglycerides to total lipids in large VLDL percentage (UKB data field 23593) 88,321 European ancestry individuals A 0.353893 8E-196 195.097 rs7350789 0.147002 triglycerides to total lipids in large VLDL percentage (EFO:0022332)
PMID:36764567
GWAS750657_H GCST90299542 Metabolite levels (1-arachidonoylglycerophosphoethanolamine; 1-arachidonoyl-GPE (20:4n6); C20:4 LPE; C20_4_LPE) 11,272 European, Hispanic or African American individuals A 0.3399 2E-27 26.699 rs7350789 0.154 1-arachidonoyl-GPE (20:4n6) measurement (EFO:0800248)
PMID:37253714
GWAS751008_H GCST90299688 Metabolite levels (1-linoleoylglycerophosphoethanolamine; 1-linoleoyl-GPE (18:2); C18:2 LPE; C18_2_LPE) 11,268 European, Hispanic or African American individuals A 0.3399 5E-18 17.302 rs7350789 0.123 1-linoleoyl-GPE (18:2) measurement (EFO:0800247)
PMID:37253714
None Available GCST90091604 Fasting sphingomyelins null A 0.355478417 2E-12 11.699 rs7350789 0.150708 sphingomyelin measurement (EFO:0010118)
PMID:34610981
None Available GCST90091669 Postprandial free cholesterol in IDL null A 0.357569489 9E-11 10.046 rs7350789 0.143914 free cholesterol measurement (EFO:0008591)
intermediate density lipoprotein measurement (EFO:0008595)
PMID:34610981
Database Acc Id Source(s)
GWAS Catalog GCST009240 GWAS Catalog

RGD Curation Notes
Note Type Note Reference