GWAS623300_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS623300_H (forced expiratory volume QTL GWAS623300 (human)) Homo sapiens

Symbol: GWAS623300_H
Name: forced expiratory volume QTL GWAS623300 (human)
RGD ID: 406974324
Trait: forced expiratory volume
Measurement Type: forced expiratory volume   (CMO:0000254)    
LOD Score: Not Available
P Value: 8.0E-58
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381265,965,972 - 65,965,973RGD_MAPPER_PIPELINEGRCh38
GRCh371266,359,752 - 66,359,753RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS623300_HHumanforced expiratory volume  IAGPrs8756405850206Based on the EFO term IDGWAS_CATALOGPMID:36641522

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS623300_HHumanforced expiratory volume  IAGPrs8756405850206 GWAS_CATALOGPMID:36641522
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348013HMGA2high mobility group AT-hook 2126582446065966291Human

Position Markers

Peak: (rs8756)
Human AssemblyChrPosition (strand)Source
GRCh381265,965,972 - 65,965,973RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406925056GWAS574032_Hbody height QTL GWAS574032 (human)1e-140body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407029825GWAS678801_Hvital capacity QTL GWAS678801 (human)1e-63vital capacity126596597265965973Human
407081541GWAS730517_Hbody height QTL GWAS730517 (human)5e-90body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407026117GWAS675093_Hbody height QTL GWAS675093 (human)5e-14body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407048004GWAS696980_Hcortical surface area measurement QTL GWAS696980 (human)8e-16cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
406988431GWAS637407_Hsmoking cessation QTL GWAS637407 (human)1e-09smoking cessation126596597265965973Human
406924942GWAS573918_Hbody height QTL GWAS573918 (human)1e-300body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407282569GWAS931545_Hbrain measurement QTL GWAS931545 (human)7e-21brain measurementbrain measurement (CMO:0000911)126596597265965973Human
407214730GWAS863706_Hbody height QTL GWAS863706 (human)5e-12body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407164180GWAS813156_Hcortical thickness QTL GWAS813156 (human)5e-11cortical thickness126596597265965973Human
407051538GWAS700514_Hcortical surface area measurement QTL GWAS700514 (human)7e-15cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407337811GWAS986787_Hneutrophil count QTL GWAS986787 (human)9e-13neutrophil quantity (VT:0000222)blood neutrophil count (CMO:0000030)126596597265965973Human
406993627GWAS642603_Hsex hormone-binding globulin measurement QTL GWAS642603 (human)9e-11sex hormone-binding globulin measurement126596597265965973Human
406907418GWAS556394_Hbody height QTL GWAS556394 (human)3e-18body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
406991129GWAS640105_Hsex hormone-binding globulin measurement QTL GWAS640105 (human)2e-13cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
406989596GWAS638572_Hbirth weight, parental genotype effect measurement QTL GWAS638572 (human)1e-19birth weight, parental genotype effect measurementneonatal body weight (CMO:0002079)126596597265965973Human
407267161GWAS916137_Hsex hormone-binding globulin measurement QTL GWAS916137 (human)2e-09sex hormone-binding globulin measurement126596597265965973Human
406930334GWAS579310_Hsmoking cessation QTL GWAS579310 (human)4e-09sex hormone-binding globulin measurement126596597265965973Human
407049442GWAS698418_Hcortical surface area measurement QTL GWAS698418 (human)1e-12cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407020577GWAS669553_Hbody height QTL GWAS669553 (human)2e-16body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407045095GWAS694071_Hbody composition measurement QTL GWAS694071 (human)2e-15body composition measurement126596597265965973Human
407048811GWAS697787_Hcortical surface area measurement QTL GWAS697787 (human)4e-17cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407309615GWAS958591_Htriglyceride measurement QTL GWAS958591 (human)9e-09triglyceride measurementblood triglyceride level (CMO:0000118)126596597265965973Human
407019691GWAS668667_Hbody height QTL GWAS668667 (human)1e-52body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407026024GWAS675000_Hbody height QTL GWAS675000 (human)0.0000004body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407241514GWAS890490_Hmelanoma QTL GWAS890490 (human)0.000004sex hormone-binding globulin measurement126596597265965973Human
407010039GWAS659015_Hlifestyle measurement QTL GWAS659015 (human)5e-10lifestyle measurement126596597265965973Human
406974324GWAS623300_Hforced expiratory volume QTL GWAS623300 (human)8e-58forced expiratory volumeforced expiratory volume (CMO:0000254)126596597265965973Human
407050933GWAS699909_Hcortical surface area measurement QTL GWAS699909 (human)9e-17cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407317937GWAS966913_Hcortical thickness QTL GWAS966913 (human)6e-13cortical thickness126596597265965973Human
406922809GWAS571785_Hbrain volume measurement QTL GWAS571785 (human)7e-14brain volume measurementbrain morphological measurement (CMO:0000136)126596597265965973Human
407045304GWAS694280_Hcortical surface area measurement QTL GWAS694280 (human)4e-12cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407326138GWAS975114_Hcortical surface area measurement QTL GWAS975114 (human)1e-14cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)126596597265965973Human
407012541GWAS661517_Hbody height QTL GWAS661517 (human)3e-16body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
407324152GWAS973128_Hbody height QTL GWAS973128 (human)2e-141body height (VT:0001253)body height (CMO:0000106)126596597265965973Human
406991613GWAS640589_Hbody height QTL GWAS640589 (human)3e-12body height (VT:0001253)heart rate (CMO:0000002)126596597265965973Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS556394_H GCST008163 Height 1,249 whole genome sequenced European ancestry individuals, 3,541 whole genome sequenced individuals, 46,910 European ancestry individuals, 471 Carlantino (founder/genetic isolate) individuals, 1,197 Friuli Venezia Giulia (founder/genetic isolate) individuals, 1,043 Mylopotamos (founder/genetic isolate) individuals, 933 Pomak (founder/genetic isolate) individuals, 1,785 Val Borbera (founder/genetic isolate) individuals A 0.5267 3E-18 17.523 rs8756 0.059 body height (EFO:0004339)
 PMID:28552196
GWAS571785_H GCST009518 Brain region volumes 19,629 British ancestry individuals ? NR 7E-14 13.155 rs8756 N/A brain volume measurement (EFO:0006930)
 PMID:31676860
GWAS573918_H GCST90245843 Height 4,080,687 European ancestry individuals C 0.48 1E-300 300 rs8756 0.0589 body height (EFO:0004339)
 PMID:36224396
GWAS574032_H GCST90245844 Height 455,180 Hispanic or Latin American individuals C 0.3878 1E-140 140 rs8756 0.0547 body height (EFO:0004339)
 PMID:36224396
GWAS579310_H GCST90243980 Smoking cessation 1,147,272 European ancestry individuals A 0.518 4E-9 8.398 rs8756 0.0078 smoking cessation (EFO:0004319)
 PMID:36477530
GWAS623300_H GCST90270081 FEV1 383,471 European ancestry individuals ? NR 8E-58 57.097 rs8756 N/A forced expiratory volume (EFO:0004314)
 PMID:36641522
GWAS637407_H GCST90243988 Smoking cessation 1,400,535 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals A 0.556 1E-9 9 rs8756 0.00731 smoking cessation (EFO:0004319)
 PMID:36477530
GWAS638572_H GCST008363 Offspring birth weight 210,267 European ancestry individuals, 19,802 individuals C 0.486261 1E-19 19 rs8756 0.027582 birth weight (EFO:0004344)
parental genotype effect measurement (EFO:0005939)
 PMID:31043758
GWAS640105_H GCST90012106 Sex hormone-binding globulin levels adjusted for BMI 188,908 European ancestry women C 0.485175 2E-13 12.699 rs8756 0.00845938 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS640589_H GCST008053 Height 17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals ? NR 3E-12 11.523 rs8756 0.04180514 body height (EFO:0004339)
 PMID:31217584
GWAS642603_H GCST90012107 Sex hormone-binding globulin levels 189,473 European ancestry women C 0.485175 9E-11 10.046 rs8756 0.00876032 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
None Available GCST007656 Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) 12,550 European and unknown ancestry chronic obstructive pulmonary disease cases, 46,368 European and unknown ancestry controls, 458,969 European ancestry individuals ? NR 3E-12 11.523 rs8756 N/A resting heart rate (EFO:0004351)
chronic obstructive pulmonary disease (EFO:0000341)
 PMID:30940143
GWAS659015_H GCST010084 Leisure sedentary behaviour (television watching) 408,815 European ancestry individuals ? NR 5E-10 9.302 rs8756 0.0134501 lifestyle measurement (EFO:0010724)
 PMID:32317632
GWAS661517_H GCST90245845 Height 472,730 East Asian ancestry individuals C 0.1224 3E-16 15.523 rs8756 0.029 body height (EFO:0004339)
 PMID:36224396
GWAS668667_H GCST90245846 Height 293,593 African ancestry individuals C 0.40975 1E-52 52 rs8756 0.04629 body height (EFO:0004339)
 PMID:36224396
GWAS669553_H GCST000175 Height 30,968 European ancestry individuals C 0.52 2E-16 15.699 rs8756 6.6 body height (EFO:0004339)
 PMID:18391951
GWAS675000_H GCST000644 Height 11,536 European ancestry individuals A 0.51 4E-7 6.398 rs8756 0.07 body height (EFO:0004339)
 PMID:20397748
GWAS675093_H GCST000372 Height 12,611 European ancestry individuals ? 0.17 5E-14 13.302 rs8756 0.08 body height (EFO:0004339)
 PMID:19343178
GWAS678801_H GCST90270083 FVC 383,471 European ancestry individuals ? NR 1E-63 63 rs8756 N/A vital capacity (EFO:0004312)
 PMID:36641522
GWAS694071_H GCST90267367 Body composition (MOSTest) 33,588 European ancestry individuals ? NR 2E-15 14.699 rs8756 7.91 body composition measurement (EFO:0005106)
 PMID:36402844
GWAS694280_H GCST90271793 Inferior parietal area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 4E-12 11.398 rs8756 0.0484 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS696980_H GCST90271814 Cortical surface area 32,488 European ancestry individuals ? NR 8E-16 15.097 rs8756 0.0546 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS697787_H GCST90271801 Superior temporal area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 4E-17 16.398 rs8756 0.0587 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS698418_H GCST90271791 Dorsolateral prefrontal area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 1E-12 12 rs8756 0.0496 cortical surface area measurement (EFO:0010736)
 PMID:36893272
None Available GCST90271798 Posterolateral temporal area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 2E-13 12.699 rs8756 0.0513 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS699909_H GCST90271797 Parsopercularis area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 9E-17 16.046 rs8756 0.058 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS700514_H GCST90271790 Anteromedial temporal area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 7E-15 14.155 rs8756 0.0542 cortical surface area measurement (EFO:0010736)
 PMID:36893272
GWAS730517_H GCST002647 Height 253,288 European ancestry individuals A 0.508 5E-90 89.302 rs8756 0.059 body height (EFO:0004339)
 PMID:25282103
GWAS813156_H GCST90091061 Cortical thickness 35,657 White British ancestry individuals C 0.4881 5E-11 10.302 rs8756 N/A cortical thickness (EFO:0004840)
 PMID:34560273
GWAS863706_H GCST90095033 Height 59,771 Hispanic or Latin American individuals A 0.6507 5E-12 11.302 rs8756 0.0394 body height (EFO:0004339)
 PMID:35399580
None Available GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals C 0.4401 1E-300 300 rs8756 0.0569 body height (EFO:0004339)
 PMID:36224396
GWAS890490_H GCST90027057 Melanoma 3,122 White British ancestry cases, 271,708 White British ancestry controls ? NR 0.000004 5.398 rs8756 1.12601 melanoma (EFO:0000756)
 PMID:34290314
None Available GCST90104277 Sex hormone-binding globulin levels in postmenopausal women 92,911 European ancestry individuals C 0.474012 0.000004 5.398 rs8756 0.0214474 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS916137_H GCST90104273 Sex hormone-binding globulin levels 196,901 European ancestry individuals C 0.474012 2E-9 8.699 rs8756 0.0190399 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
None Available GCST90104297 Sex hormone-binding globulin levels 4,522 African ancestry individuals, 196,901 European ancestry individuals ? NR 4E-9 8.398 rs8756 5.893 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:35192695
GWAS931545_H GCST90095129 Vertex-wise sulcal depth 33,748 European ancestry individuals C 0.45 7E-21 20.155 rs8756 9.37 brain measurement (EFO:0004464)
 PMID:34910505
GWAS958591_H GCST90239664 Triglyceride levels 1,320,016 European ancestry individuals A 0.509079 9E-9 8.046 rs8756 0.00972395 triglyceride measurement (EFO:0004530)
 PMID:34887591
GWAS966913_H GCST90095131 Vertex-wise cortical thickness 33,748 European ancestry individuals C 0.45 6E-13 12.222 rs8756 7.19 cortical thickness (EFO:0004840)
 PMID:34910505
GWAS973128_H GCST90018959 Height 360,388 European ancestry individuals, 165,056 East Asian ancestry individuals A NR 2E-141 140.699 rs8756 0.0364 body height (EFO:0004339)
 PMID:34594039
GWAS975114_H GCST90095130 Vertex-wise cortical surface area 33,748 European ancestry individuals C 0.45 1E-14 14 rs8756 7.74 cortical surface area measurement (EFO:0010736)
 PMID:34910505
GWAS986787_H GCST90018968 Neutrophil count 349,856 European ancestry individuals, 82,810 East Asian ancestry individuals A NR 9E-13 12.046 rs8756 0.0161 neutrophil count (EFO:0004833)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90270081 GWAS Catalog

RGD Curation Notes
Note Type Note Reference