QTL |
GWAS Catalog Study |
Disease Trait |
Study Size |
Risk Allele |
Risk Allele Frequency |
P Value |
P Value MLOG |
Peak Marker |
Reported Odds Ratio or Beta-coefficient |
Ontology Accession |
PubMed |
GWAS1115383_H |
GCST006188 |
Systolic blood pressure (cigarette smoking interaction) |
80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals |
? |
NR |
2E-54 |
53.699 |
rs880315 |
N/A |
smoking status measurement (EFO:0006527) systolic blood pressure (EFO:0006335)
|
PMID:29455858 |
GWAS1115581_H |
GCST006187 |
Diastolic blood pressure (cigarette smoking interaction) |
80,552 European ancestry individuals, 27,118 African individuals, 13,438 Asian individuals, 8,805 Hispanic individuals |
? |
NR |
7E-42 |
41.155 |
rs880315 |
N/A |
smoking status measurement (EFO:0006527) diastolic blood pressure (EFO:0006336)
|
PMID:29455858 |
GWAS1635854_H |
GCST90475755 |
Hypopotassemia (PheCode 276.14) |
23,659 European ancestry cases, 402,078 European ancestry controls |
T |
0.6549 |
1E-13 |
13 |
rs880315 |
0.07062 |
|
PMID:39024449 |
GWAS1638370_H |
GCST90479553 |
High blood pressure / hypertension |
38,518 African American or Afro-Caribbean cases, 16,987 African American or Afro-Caribbean controls, 16,330 Hispanic or Latin American cases, 12,984 Hispanic or Latin American controls, 2,059 East Asian ancestry cases, 1,488 East Asian ancestry controls, 191,352 European ancestry cases, 124,316 European ancestry controls |
T |
0.6677 |
1E-32 |
32 |
rs880315 |
0.07187 |
hypertension (EFO:0000537)
|
PMID:39024449 |
GWAS1122128_H |
GCST007706 |
Mean arterial pressure |
130,777 Japanese ancestry individuals |
T |
0.3193 |
3E-23 |
22.523 |
rs880315 |
0.4872 |
mean arterial pressure (EFO:0006340)
|
PMID:30487518 |
GWAS1122547_H |
GCST007707 |
Hypertension |
22,566 Japanese ancestry cases, 28,226 Japanese ancestry controls |
T |
0.3194 |
7E-24 |
23.155 |
rs880315 |
0.1224 |
hypertension (EFO:0000537)
|
PMID:30487518 |
GWAS1123223_H |
GCST007703 |
Systolic blood pressure |
130,777 Japanese ancestry individuals |
T |
0.3193 |
1E-23 |
23 |
rs880315 |
0.6998 |
systolic blood pressure (EFO:0006335)
|
PMID:30487518 |
GWAS1123475_H |
GCST007704 |
Diastolic blood pressure |
130,777 Japanese ancestry individuals |
T |
0.3193 |
1E-18 |
18 |
rs880315 |
0.3849 |
diastolic blood pressure (EFO:0006336)
|
PMID:30487518 |
GWAS1643491_H |
GCST90479580 |
diastolic blood pressure (DBP, maximum, inv-normal transformed) |
119,274 African American or Afro-Caribbean individuals, 57,979 Hispanic or Latin American individuals, 6,421 East Asian ancestry individuals, 425,680 European ancestry individuals |
T |
0.6738 |
8E-45 |
44.097 |
rs880315 |
0.03798 |
diastolic blood pressure (EFO:0006336)
|
PMID:39024449 |
GWAS1643761_H |
GCST90479581 |
diastolic blood pressure (DBP, mean, inv-normal transformed) |
119,332 African American or Afro-Caribbean individuals, 57,990 Hispanic or Latin American individuals, 6,421 East Asian ancestry individuals, 425,743 European ancestry individuals |
T |
0.6738 |
6E-45 |
44.222 |
rs880315 |
0.03872 |
diastolic blood pressure change measurement (EFO:0006945)
|
PMID:39024449 |
GWAS1644140_H |
GCST90475538 |
neutrophil (fraction, mean, inv-norm transformed) |
261,847 European ancestry individuals |
T |
0.6541 |
2E-12 |
11.699 |
rs880315 |
0.02214 |
neutrophil count (EFO:0004833)
|
PMID:39024449 |
GWAS1127303_H |
GCST006061 |
Atrial fibrillation |
55,114 European ancestry cases, 482,295 European ancestry controls, 8,180 Japanese ancestry cases, 28,612 Japanese ancestry controls, 1,307 African American ancestry cases, 7,660 African American ancestry controls, 845 Hispanic cases, 4,177 Hispanic controls |
C |
0.37 |
5E-9 |
8.302 |
rs880315 |
1.04 |
atrial fibrillation (EFO:0000275)
|
PMID:29892015 |
GWAS578590_H |
GCST010244 |
Triglyceride levels |
441,016 European ancestry individuals |
T |
0.65979 |
2E-8 |
7.699 |
rs880315 |
0.0119226 |
triglyceride measurement (EFO:0004530)
|
PMID:32203549 |
GWAS1130510_H |
GCST010245 |
LDL cholesterol levels |
440,546 European ancestry individuals |
T |
0.659761 |
7E-12 |
11.155 |
rs880315 |
0.015148 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:32203549 |
GWAS1646696_H |
GCST90475919 |
Hypertension (PheCode 401) |
322,448 European ancestry cases, 105,690 European ancestry controls |
T |
0.6541 |
1E-27 |
27 |
rs880315 |
0.05394 |
hypertension (EFO:0000537)
|
PMID:39024449 |
GWAS1133727_H |
GCST007705 |
Pulse pressure |
130,777 Japanese ancestry individuals |
T |
0.3193 |
8E-12 |
11.097 |
rs880315 |
0.3262 |
pulse pressure measurement (EFO:0005763)
|
PMID:30487518 |
None Available |
GCST90475922 |
Essential hypertension (PheCode 401.1) |
320,429 European ancestry cases, 107,275 European ancestry controls |
T |
0.654 |
1E-27 |
27 |
rs880315 |
0.05318 |
|
PMID:39024449 |
GWAS601223_H |
GCST006259 |
Systolic blood pressure |
up to 201,529 European ancestry individuals |
T |
0.641 |
2E-14 |
13.699 |
rs880315 |
0.475 |
systolic blood pressure (EFO:0006335)
|
PMID:27618452 |
GWAS1145040_H |
GCST007072 |
Cardiovascular disease |
approximately 459,000 European ancestry individuals |
? |
NR |
2E-24 |
23.699 |
rs880315 |
N/A |
cardiovascular disease (EFO:0000319)
|
PMID:30595370 |
GWAS610691_H |
GCST002630 |
Systolic blood pressure |
11,816 Han Chinese ancestry individuals |
C |
0.63 |
6E-10 |
9.222 |
rs880315 |
0.97 |
systolic blood pressure (EFO:0006335)
|
PMID:25249183 |
GWAS610698_H |
GCST002631 |
Diastolic blood pressure |
11,816 Han Chinese ancestry individuals |
C |
0.63 |
8E-8 |
7.097 |
rs880315 |
0.46 |
diastolic blood pressure (EFO:0006336)
|
PMID:25249183 |
GWAS611748_H |
GCST002627 |
Hypertension |
5,065 Han Chinese ancestry cases, 4,404 Han Chinese ancestry controls |
C |
0.63 |
2E-9 |
8.699 |
rs880315 |
N/A |
hypertension (EFO:0000537)
|
PMID:25249183 |
GWAS1650604_H |
GCST90476307 |
potassium (mean, inv-norm transformed) |
421,503 European ancestry individuals |
T |
0.6544 |
3E-59 |
58.523 |
rs880315 |
0.04133 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
GWAS1650632_H |
GCST90476309 |
potassium (minimum, inv-norm transformed) |
118,507 African American or Afro-Caribbean individuals |
T |
0.8172 |
3E-12 |
11.523 |
rs880315 |
0.0371 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
None Available |
GCST90476304 |
potassium (maximum, inv-norm transformed) |
421,297 European ancestry individuals |
T |
0.6544 |
1E-23 |
23 |
rs880315 |
0.02468 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
None Available |
GCST90476306 |
potassium (mean, inv-norm transformed) |
118,506 African American or Afro-Caribbean individuals |
T |
0.8172 |
1E-18 |
18 |
rs880315 |
0.04938 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
GWAS619631_H |
GCST006258 |
Diastolic blood pressure |
up to 201,529 European ancestry individuals |
T |
0.641 |
1E-11 |
11 |
rs880315 |
0.257 |
diastolic blood pressure (EFO:0006336)
|
PMID:27618452 |
GWAS1651142_H |
GCST90475214 |
High blood pressure / hypertension |
191,352 European ancestry cases, 124,316 European ancestry controls |
T |
0.6551 |
3E-42 |
41.523 |
rs880315 |
0.06603 |
hypertension (EFO:0000537)
|
PMID:39024449 |
None Available |
GCST90475213 |
High blood pressure / hypertension |
38,518 African American or Afro-Caribbean cases, 16,987 African American or Afro-Caribbean controls |
T |
0.8175 |
3E-12 |
11.523 |
rs880315 |
0.1261 |
hypertension (EFO:0000537)
|
PMID:39024449 |
GWAS1652067_H |
GCST90475216 |
Takes medication for high blood pressure? |
179,356 European ancestry cases, 136,312 European ancestry controls |
T |
0.6551 |
1E-38 |
38 |
rs880315 |
0.06266 |
hypertension (EFO:0000537) Antihypertensive use measurement (EFO:0009927)
|
PMID:39024449 |
GWAS1652760_H |
GCST90475252 |
diastolic blood pressure (DBP, maximum, inv-normal transformed) |
425,680 European ancestry individuals |
T |
0.6544 |
6E-42 |
41.222 |
rs880315 |
0.03499 |
diastolic blood pressure (EFO:0006336)
|
PMID:39024449 |
GWAS1158661_H |
GCST004775 |
Pulse pressure |
150,134 European ancestry individuals |
C |
0.351 |
2E-10 |
9.699 |
rs880315 |
0.331 |
pulse pressure measurement (EFO:0005763)
|
PMID:28739976 |
GWAS1652799_H |
GCST90475254 |
diastolic blood pressure (DBP, mean, inv-normal transformed) |
119,332 African American or Afro-Caribbean individuals |
T |
0.8173 |
3E-18 |
17.523 |
rs880315 |
0.04754 |
diastolic blood pressure change measurement (EFO:0006945)
|
PMID:39024449 |
GWAS1652800_H |
GCST90475253 |
diastolic blood pressure (DBP, mean, inv-normal transformed) |
57,990 Hispanic or Latin American individuals |
T |
0.5452 |
7E-13 |
12.155 |
rs880315 |
0.04325 |
diastolic blood pressure change measurement (EFO:0006945)
|
PMID:39024449 |
GWAS1653046_H |
GCST90475255 |
diastolic blood pressure (DBP, mean, inv-normal transformed) |
425,743 European ancestry individuals |
T |
0.6544 |
4E-43 |
42.398 |
rs880315 |
0.03522 |
diastolic blood pressure change measurement (EFO:0006945)
|
PMID:39024449 |
GWAS1161972_H |
GCST004776 |
Systolic blood pressure |
150,134 European ancestry individuals |
C |
0.351 |
9E-16 |
15.046 |
rs880315 |
0.64 |
systolic blood pressure (EFO:0006335)
|
PMID:28739976 |
GWAS1162263_H |
GCST004777 |
Diastolic blood pressure |
150,134 European ancestry individuals |
C |
0.351 |
4E-10 |
9.398 |
rs880315 |
0.302 |
diastolic blood pressure (EFO:0006336)
|
PMID:28739976 |
GWAS1654229_H |
GCST90475435 |
lymphocyte (fraction, mean, inv-norm transformed) |
290,958 European ancestry individuals |
T |
0.6542 |
3E-13 |
12.523 |
rs880315 |
0.02104 |
lymphocyte count (EFO:0004587)
|
PMID:39024449 |
GWAS1163401_H |
GCST006020 |
Diastolic blood pressure |
up to 165,276 European ancestry individuals, up to 27,487 South Asian ancestry individuals |
T |
0.6333 |
6E-16 |
15.222 |
rs880315 |
0.0269 |
diastolic blood pressure (EFO:0006336)
|
PMID:27618447 |
GWAS649043_H |
GCST007096 |
Pulse pressure |
295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals |
T |
NR |
6E-9 |
8.222 |
rs880315 |
0.168 |
pulse pressure measurement (EFO:0005763)
|
PMID:27841878 |
GWAS649973_H |
GCST007094 |
Diastolic blood pressure |
295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals |
T |
NR |
2E-12 |
11.699 |
rs880315 |
0.185 |
diastolic blood pressure (EFO:0006336)
|
PMID:27841878 |
GWAS650761_H |
GCST007098 |
Diastolic blood pressure |
80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals |
T |
NR |
6E-8 |
7.222 |
rs880315 |
0.229 |
diastolic blood pressure (EFO:0006336)
|
PMID:27841878 |
GWAS650762_H |
GCST007098 |
Diastolic blood pressure |
80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals |
T |
NR |
0.000007 |
5.155 |
rs880315 |
0.211 |
diastolic blood pressure (EFO:0006336)
|
PMID:27841878 |
GWAS650835_H |
GCST007099 |
Systolic blood pressure |
295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals |
T |
NR |
5E-17 |
16.302 |
rs880315 |
0.364 |
systolic blood pressure (EFO:0006335)
|
PMID:27841878 |
GWAS650998_H |
GCST007095 |
Systolic blood pressure |
80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals |
T |
NR |
1E-7 |
7 |
rs880315 |
0.345 |
systolic blood pressure (EFO:0006335)
|
PMID:27841878 |
GWAS1167204_H |
GCST005979 |
Systolic blood pressure |
136,597 Japanese ancestry individuals |
? |
NR |
7E-18 |
17.155 |
rs880315 |
0.03499 |
systolic blood pressure (EFO:0006335)
|
PMID:29403010 |
GWAS1167259_H |
GCST005978 |
Diastolic blood pressure |
136,615 Japanese ancestry individuals |
? |
NR |
6E-12 |
11.222 |
rs880315 |
0.02794 |
diastolic blood pressure (EFO:0006336)
|
PMID:29403010 |
GWAS1167309_H |
GCST006010 |
Mean arterial pressure |
136,482 Japanese ancestry individuals |
? |
NR |
2E-16 |
15.699 |
rs880315 |
0.03378 |
mean arterial pressure (EFO:0006340)
|
PMID:29403010 |
None Available |
GCST006009 |
Pulse pressure |
136,249 Japanese ancestry individuals |
? |
NR |
5E-9 |
8.302 |
rs880315 |
0.02362 |
pulse pressure measurement (EFO:0005763)
|
PMID:29403010 |
None Available |
GCST90479519 |
Bicarbonate (mean, inv-norm transformed) |
112,877 African American or Afro-Caribbean individuals, 54,571 Hispanic or Latin American individuals, 5,460 East Asian ancestry individuals, 412,513 European ancestry individuals |
T |
0.6739 |
1E-13 |
13 |
rs880315 |
0.02033 |
obsolete_blood bicarbonate measurement (EFO:0011012)
|
PMID:39024449 |
None Available |
GCST006231 |
Mean arterial pressure |
120,473 European ancestry individuals, 21,503 African American individuals, 4,586 Hispanic individuals |
G |
0.320712336691543 |
5E-17 |
16.302 |
rs880315 |
0.40930188 |
mean arterial pressure (EFO:0006340)
|
PMID:27618448 |
GWAS670084_H |
GCST001072 |
Blood pressure |
19,608 East Asian ancestry individuals |
C |
0.65 |
7E-7 |
6.155 |
rs880315 |
0.74 |
systolic blood pressure (EFO:0006335)
|
PMID:21572416 |
GWAS670099_H |
GCST001074 |
Blood pressure |
19,608 East Asian ancestry individuals |
C |
0.65 |
3E-10 |
9.523 |
rs880315 |
0.56 |
diastolic blood pressure (EFO:0006336)
|
PMID:21572416 |
GWAS1659193_H |
GCST90479552 |
Takes medication for high blood pressure? |
35,848 African American or Afro-Caribbean cases, 19,657 African American or Afro-Caribbean controls, 14,901 Hispanic or Latin American cases, 14,413 Hispanic or Latin American controls, 1,884 East Asian ancestry cases, 1,663 East Asian ancestry controls, 179,356 European ancestry cases, 136,312 European ancestry controls |
T |
0.6677 |
6E-29 |
28.222 |
rs880315 |
0.0664 |
hypertension (EFO:0000537) Antihypertensive use measurement (EFO:0009927)
|
PMID:39024449 |
None Available |
GCST90475094 |
Hemoglobin A1c (HbA1c, mean, inv-norm transformed) |
338,848 European ancestry individuals |
T |
0.6545 |
3E-12 |
11.523 |
rs880315 |
0.02087 |
HbA1c measurement (EFO:0004541)
|
PMID:39024449 |
GWAS1663807_H |
GCST90476403 |
systolic blood pressure (SBP, mean, inv-normal transformed) |
425,740 European ancestry individuals |
T |
0.6544 |
4E-58 |
57.398 |
rs880315 |
0.04216 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
GWAS1663872_H |
GCST90476399 |
systolic blood pressure (SBP, maximum, inv-normal transformed) |
119,334 African American or Afro-Caribbean individuals |
T |
0.8173 |
2E-15 |
14.699 |
rs880315 |
0.04225 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
None Available |
GCST90476395 |
Sodium (mean, inv-norm transformed) |
421,240 European ancestry individuals |
T |
0.6544 |
7E-24 |
23.155 |
rs880315 |
0.02667 |
sodium measurement (EFO:0009282)
|
PMID:39024449 |
GWAS1664081_H |
GCST90476401 |
systolic blood pressure (SBP, mean, inv-normal transformed) |
57,988 Hispanic or Latin American individuals |
T |
0.5452 |
3E-11 |
10.523 |
rs880315 |
0.03857 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
GWAS1664179_H |
GCST90476400 |
systolic blood pressure (SBP, maximum, inv-normal transformed) |
425,750 European ancestry individuals |
T |
0.6544 |
3E-50 |
49.523 |
rs880315 |
0.03746 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
GWAS1189492_H |
GCST003255 |
Urinary albumin-to-creatinine ratio |
up to 54,450 European ancestry individuals |
T |
0.65 |
0.000009 |
5.046 |
rs880315 |
0.042 |
urinary albumin to creatinine ratio (EFO:0007778)
|
PMID:26631737 |
GWAS1665172_H |
GCST90479944 |
Hypopotassemia (PheCode 276.14) |
10,895 African American or Afro-Caribbean cases, 101,696 African American or Afro-Caribbean controls, 23,659 European ancestry cases, 402,078 European ancestry controls, 2,763 Hispanic or Latin American cases, 53,922 Hispanic or Latin American controls |
T |
0.6753 |
6E-20 |
19.222 |
rs880315 |
0.07965 |
|
PMID:39024449 |
GWAS1666647_H |
GCST90475148 |
Bicarbonate (mean, inv-norm transformed) |
412,513 European ancestry individuals |
T |
0.6544 |
1E-16 |
16 |
rs880315 |
0.02232 |
obsolete_blood bicarbonate measurement (EFO:0011012)
|
PMID:39024449 |
GWAS1206107_H |
GCST007929 |
Medication use (calcium channel blockers) |
31,904 European ancestry cases, 172,474 European ancestry controls |
C |
0.339218 |
1E-30 |
30 |
rs880315 |
0.09883418 |
Calcium channel blocker use measurement (EFO:0009930)
|
PMID:31015401 |
GWAS1670696_H |
GCST90480653 |
potassium (maximum, inv-norm transformed) |
118,330 African American or Afro-Caribbean individuals, 57,381 Hispanic or Latin American individuals, 6,307 East Asian ancestry individuals, 421,297 European ancestry individuals |
T |
0.6739 |
3E-27 |
26.523 |
rs880315 |
0.02664 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
GWAS1670814_H |
GCST90480655 |
potassium (minimum, inv-norm transformed) |
118,507 African American or Afro-Caribbean individuals, 57,434 Hispanic or Latin American individuals, 6,313 East Asian ancestry individuals, 421,506 European ancestry individuals |
T |
0.6739 |
2E-44 |
43.699 |
rs880315 |
0.03489 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
GWAS1670989_H |
GCST90480703 |
Sodium (mean, inv-norm transformed) |
118,487 African American or Afro-Caribbean individuals, 57,407 Hispanic or Latin American individuals, 6,310 East Asian ancestry individuals, 421,240 European ancestry individuals |
T |
0.6739 |
6E-25 |
24.222 |
rs880315 |
0.02727 |
sodium measurement (EFO:0009282)
|
PMID:39024449 |
GWAS1671118_H |
GCST90480705 |
systolic blood pressure (SBP, maximum, inv-normal transformed) |
119,334 African American or Afro-Caribbean individuals, 57,991 Hispanic or Latin American individuals, 6,422 East Asian ancestry individuals, 425,750 European ancestry individuals |
T |
0.6738 |
2E-42 |
41.699 |
rs880315 |
0.0366 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
None Available |
GCST90480704 |
sodium (minimum, inv-norm transformed) |
118,415 African American or Afro-Caribbean individuals, 57,381 Hispanic or Latin American individuals, 6,302 East Asian ancestry individuals, 421,073 European ancestry individuals |
T |
0.6739 |
6E-12 |
11.222 |
rs880315 |
0.01723 |
sodium measurement (EFO:0009282)
|
PMID:39024449 |
GWAS1671222_H |
GCST90480654 |
potassium (mean, inv-norm transformed) |
118,506 African American or Afro-Caribbean individuals, 57,434 Hispanic or Latin American individuals, 6,313 East Asian ancestry individuals, 421,503 European ancestry individuals |
T |
0.6739 |
8E-59 |
58.097 |
rs880315 |
0.04161 |
potassium measurement (EFO:0009283)
|
PMID:39024449 |
GWAS1671273_H |
GCST90480702 |
sodium (maximum, inv-norm transformed) |
118,412 African American or Afro-Caribbean individuals, 57,401 Hispanic or Latin American individuals, 6,311 East Asian ancestry individuals, 421,132 European ancestry individuals |
T |
0.6739 |
2E-21 |
20.699 |
rs880315 |
0.02362 |
sodium measurement (EFO:0009282)
|
PMID:39024449 |
None Available |
GCST90480706 |
systolic blood pressure (SBP, mean, inv-normal transformed) |
119,331 African American or Afro-Caribbean individuals, 57,988 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,740 European ancestry individuals |
T |
0.6738 |
3E-50 |
49.523 |
rs880315 |
0.0415 |
systolic blood pressure (EFO:0006335)
|
PMID:39024449 |
GWAS1675448_H |
GCST90480128 |
Hypertension (PheCode 401) |
94,292 African American or Afro-Caribbean cases, 22,643 African American or Afro-Caribbean controls, 35,766 Hispanic or Latin American cases, 20,913 Hispanic or Latin American controls, 3,903 East Asian ancestry cases, 2,607 East Asian ancestry controls, 322,448 European ancestry cases, 105,690 European ancestry controls |
T |
0.673 |
5E-24 |
23.302 |
rs880315 |
0.06099 |
hypertension (EFO:0000537)
|
PMID:39024449 |
None Available |
GCST90480125 |
Essential hypertension (PheCode 401.1) |
93,857 African American or Afro-Caribbean cases, 22,988 African American or Afro-Caribbean controls, 35,551 Hispanic or Latin American cases, 21,134 Hispanic or Latin American controls, 3,880 East Asian ancestry cases, 2,626 East Asian ancestry controls, 320,429 European ancestry cases, 107,275 European ancestry controls |
T |
0.6729 |
5E-24 |
23.302 |
rs880315 |
0.06066 |
|
PMID:39024449 |
GWAS1238678_H |
GCST90250905 |
Medication use for hypertension (number of purchases) |
567,671 European ancestry individuals |
? |
NR |
4E-53 |
52.398 |
rs880315 |
0.022175 |
Antihypertensive use measurement (EFO:0009927)
|
PMID:36653479 |
None Available |
GCST90179148 |
Low-density lipoprotein levels (MTAG) |
361,194 European ancestry individuals |
T |
NR |
6E-12 |
11.222 |
rs880315 |
0.010065 |
low density lipoprotein cholesterol measurement (EFO:0004611)
|
PMID:36376304 |
GWAS1260137_H |
GCST90018768 |
Medication use (agents acting on the renin-angiotensin system) |
45,820 East Asian ancestry cases, 132,906 East Asian ancestry controls |
C |
0.681765548 |
1E-10 |
10 |
rs880315 |
0.057121746 |
Agents acting on the renin-angiotensin system use measurement (EFO:0009931)
|
PMID:34594039 |
None Available |
GCST90018732 |
Diastolic blood pressure |
145,515 East Asian ancestry individuals |
C |
0.681036 |
8E-12 |
11.097 |
rs880315 |
0.0255041 |
diastolic blood pressure (EFO:0006336)
|
PMID:34594039 |
GWAS1291352_H |
GCST90278642 |
Systolic blood pressure |
92,615 Taiwanese ancestry individuals |
? |
NR |
4E-12 |
11.398 |
rs880315 |
N/A |
systolic blood pressure (EFO:0006335)
|
PMID:38116116 |
None Available |
GCST90278625 |
Diastolic blood pressure |
92,615 Taiwanese ancestry individuals |
? |
NR |
4E-10 |
9.398 |
rs880315 |
N/A |
diastolic blood pressure (EFO:0006336)
|
PMID:38116116 |
None Available |
GCST007930 |
Medication use (agents acting on the renin-angiotensin system) |
62,752 European ancestry cases, 174,778 European ancestry controls |
C |
0.339584 |
7E-24 |
23.155 |
rs880315 |
0.06473087 |
Agents acting on the renin-angiotensin system use measurement (EFO:0009931)
|
PMID:31015401 |
GWAS1303579_H |
GCST007928 |
Medication use (diuretics) |
34,453 European ancestry cases, 194,633 European ancestry controls |
C |
0.337723 |
2E-26 |
25.699 |
rs880315 |
0.089395955 |
Diuretic use measurement (EFO:0009928)
|
PMID:31015401 |
GWAS1354947_H |
GCST90239673 |
Total cholesterol levels |
40,963 South Asian ancestry individuals, 48,057 Hispanic individuals, 99,432 Admixed African or African ancestry individuals, 146,492 East Asian ancestry individuals, 1,320,016 European ancestry individuals |
? |
NR |
9E-11 |
10.046 |
rs880315 |
N/A |
total cholesterol measurement (EFO:0004574)
|
PMID:34887591 |
None Available |
GCST90239676 |
Total cholesterol levels |
1,320,016 European ancestry individuals |
C |
0.347697 |
1E-10 |
10 |
rs880315 |
0.0109666 |
total cholesterol measurement (EFO:0004574)
|
PMID:34887591 |
None Available |
GCST90093274 |
Mean arterial pressure x low social support interaction (2df test) |
14,923 African American individuals, 24,943 European ancestry individuals, 749 Asian ancestry individuals, 4,425 Hispanic individuals |
? |
NR |
2E-9 |
8.699 |
rs880315 |
N/A |
mean arterial pressure (EFO:0006340) social deprivation (EFO:0009696)
|
PMID:34734193 |
GWAS1381594_H |
GCST90335163 |
Systolic blood pressure (BMI adjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
2E-22 |
21.699 |
rs880315 |
0.9612 |
systolic blood pressure (EFO:0006335)
|
PMID:39048560 |
GWAS1381679_H |
GCST005841 |
Ischemic stroke (small-vessel) |
5,386 European ancestry cases, 343,560 European ancestry controls, 5,096 East Asian ancestry cases, 28,195 East Asian ancestry controls, 314 South Asian ancestry cases, 6,707 South Asian ancestry controls, 694 African American cases, 15,146 African American controls, 134 Asian ancestry cases, 333 Asian ancestry controls, 86 Latin American cases, 692 Latin American controls |
? |
NR |
0.000003 |
5.523 |
rs880315 |
N/A |
small vessel stroke (EFO:1001504)
|
PMID:29531354 |
None Available |
GCST005838 |
Stroke |
40,585 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,154 African American controls, 365 Asian ancestry cases, 333 Asian ancestry controls, 865 Latin American cases, 692 Latin American controls |
? |
NR |
4E-10 |
9.398 |
rs880315 |
N/A |
stroke (EFO:0000712)
|
PMID:29531354 |
GWAS1382308_H |
GCST006906 |
Stroke |
40,585 European ancestry cases, 406,111 European ancestry controls |
? |
NR |
7E-8 |
7.155 |
rs880315 |
N/A |
stroke (EFO:0000712)
|
PMID:29531354 |
None Available |
GCST90335167 |
Pulse pressure (BMI adjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
1E-11 |
11 |
rs880315 |
0.4564 |
pulse pressure measurement (EFO:0005763)
|
PMID:39048560 |
GWAS1382489_H |
GCST006908 |
Ischemic stroke |
34,217 European ancestry cases, 406,111 European ancestry controls |
? |
NR |
0.000001 |
6 |
rs880315 |
N/A |
Ischemic stroke (HP:0002140)
|
PMID:29531354 |
GWAS1383486_H |
GCST90335162 |
Systolic blood pressure (BMI unadjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
5E-23 |
22.302 |
rs880315 |
1.0178 |
systolic blood pressure (EFO:0006335)
|
PMID:39048560 |
GWAS1383718_H |
GCST90335165 |
Diastolic blood pressure (BMI adjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
1E-20 |
20 |
rs880315 |
0.4975 |
diastolic blood pressure (EFO:0006336)
|
PMID:39048560 |
GWAS1383727_H |
GCST90335166 |
Pulse pressure (BMI unadjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
3E-12 |
11.523 |
rs880315 |
0.4821 |
pulse pressure measurement (EFO:0005763)
|
PMID:39048560 |
GWAS1384135_H |
GCST90335164 |
Diastolic blood pressure (BMI unadjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
2E-21 |
20.699 |
rs880315 |
0.5285 |
diastolic blood pressure (EFO:0006336)
|
PMID:39048560 |
GWAS1384293_H |
GCST90335168 |
Mean arterial pressure (BMI unadjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
7E-25 |
24.155 |
rs880315 |
0.6917 |
mean arterial pressure (EFO:0006340)
|
PMID:39048560 |
GWAS1384623_H |
GCST90335169 |
Mean arterial pressure (BMI adjusted) |
100,453 Chinese Han ancestry individuals |
C |
0.373 |
3E-24 |
23.523 |
rs880315 |
0.6521 |
mean arterial pressure (EFO:0006340)
|
PMID:39048560 |
None Available |
GCST005843 |
Ischemic stroke |
34,217 European ancestry cases, 406,111 European ancestry controls, 17,369 East Asian ancestry cases, 28,195 East Asian ancestry controls, 2,437 South Asian ancestry cases, 6,707 South Asian ancestry controls, 5,541 African American cases, 15,146 African American controls, 222 Asian ancestry cases, 333 Asian ancestry controls, 555 Latin American cases, 692 Latin American controls |
? |
NR |
6E-9 |
8.222 |
rs880315 |
N/A |
Ischemic stroke (HP:0002140)
|
PMID:29531354 |
GWAS1386384_H |
GCST90309346 |
Hypertension (confirmatory factor analysis Factor 12) |
338,391 European ancestry individuals |
? |
NR |
1E-28 |
28 |
rs880315 |
N/A |
hypertension (EFO:0000537)
|
PMID:38965376 |
GWAS1405380_H |
GCST90018987 |
Medication use (calcium channel blockers) |
31,904 European ancestry cases, 172,474 European ancestry controls, 49,327 East Asian ancestry cases, 129,399 East Asian ancestry controls |
C |
NR |
5E-47 |
46.302 |
rs880315 |
0.0883 |
Calcium channel blocker use measurement (EFO:0009930)
|
PMID:34594039 |
GWAS1405985_H |
GCST90018986 |
Medication use (beta blocking agents) |
31,700 European ancestry cases, 192,324 European ancestry controls, 20,367 East Asian ancestry cases, 158,359 East Asian ancestry controls |
C |
NR |
7E-19 |
18.155 |
rs880315 |
0.0627 |
Beta blocking agent use measurement (EFO:0009929)
|
PMID:34594039 |
GWAS1407484_H |
GCST90018985 |
Medication use (diuretics) |
34,453 European ancestry cases, 194,633 European ancestry controls, 22,356 East Asian ancestry cases, 156,370 East Asian ancestry controls |
C |
NR |
2E-29 |
28.699 |
rs880315 |
0.076 |
Diuretic use measurement (EFO:0009928)
|
PMID:34594039 |
GWAS1408114_H |
GCST90018988 |
Medication use (agents acting on the renin-angiotensin system) |
62,752 European ancestry cases, 174,778 European ancestry controls, 45,820 East Asian ancestry cases, 132,906 East Asian ancestry controls |
C |
NR |
8E-33 |
32.097 |
rs880315 |
0.0621 |
Agents acting on the renin-angiotensin system use measurement (EFO:0009931)
|
PMID:34594039 |
GWAS1416262_H |
GCST90244680 |
Triglyceride levels in non-type 2 diabetes |
402,944 European ancestry individuals |
? |
NR |
8E-9 |
8.097 |
rs880315 |
N/A |
triglyceride measurement (EFO:0004530)
|
PMID:36269708 |
None Available |
GCST90129618 |
Aldosterone producing adenoma |
321 European ancestry cases, 950 European ancestry controls |
C |
NR |
6E-10 |
9.222 |
rs880315 |
1.5 |
aldosterone-producing adenoma (EFO:1000015)
|
PMID:36057693 |
None Available |
GCST90281355 |
Resistance to antihypertensive treatment in hypertension |
12,132 cases, 19,857 controls |
C |
NR |
0.000001 |
6 |
rs880315 |
1.09 |
treatment-resistant hypertension (EFO:1002006)
|
PMID:37151119 |
GWAS1431843_H |
GCST90204201 |
Atrial fibrillation |
77,690 European ancestry cases, 1,167,040 European ancestry controls, 67,864 Japanese ancestry cases, 1,026,594 Japanese ancestry controls |
C |
0.4062 |
4E-16 |
15.398 |
rs880315 |
0.0496 |
atrial fibrillation (EFO:0000275)
|
PMID:36653681 |