GWAS619380_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS619380_H (neuroticism measurement QTL GWAS619380 (human)) Homo sapiens

Symbol: GWAS619380_H
Name: neuroticism measurement QTL GWAS619380 (human)
RGD ID: 406970404
Trait: neuroticism measurement
LOD Score: Not Available
P Value: 2.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38117,695,363 - 17,695,364RGD_MAPPER_PIPELINEGRCh38
GRCh37118,021,858 - 18,021,859RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS619380_HHumanneuroticism measurement  IAGPrs2279817405850206 GWAS_CATALOGPMID:27089181
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1605662ARHGEF10LRho guanine nucleotide exchange factor 10 like11751343517697875Human

Position Markers

Peak: (rs2279817)
Human AssemblyChrPosition (strand)Source
GRCh38117,695,363 - 17,695,364RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
407173654GWAS822630_Hneuroticism measurement QTL GWAS822630 (human)3e-08neuroticism measurement11769536317695364Human
407174887GWAS823863_Hneuroticism measurement QTL GWAS823863 (human)2e-08neuroticism measurement11769536317695364Human
406970404GWAS619380_Hneuroticism measurement QTL GWAS619380 (human)0.000002neuroticism measurement11769536317695364Human
407172495GWAS821471_Hneuroticism measurement QTL GWAS821471 (human)4e-08neuroticism measurement11769536317695364Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS619380_H GCST003770 Neuroticism 170,911 European ancestry individuals T 0.802 0.000002 5.699 rs2279817 0.020470746 neuroticism measurement (EFO:0007660)
 PMID:27089181
GWAS821471_H GCST90027244 Neuroticism conditioned on self-rated math ability (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals ? NR 4E-8 7.398 rs2279817 N/A neuroticism measurement (EFO:0007660)
 PMID:33349686
None Available GCST90027239 Neuroticism conditioned on cognitive performance (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals ? NR 4E-8 7.398 rs2279817 N/A neuroticism measurement (EFO:0007660)
 PMID:33349686
GWAS822630_H GCST90027240 Neuroticism conditioned on Townsend deprivation index (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals ? NR 3E-8 7.523 rs2279817 N/A neuroticism measurement (EFO:0007660)
 PMID:33349686
GWAS823863_H GCST90027243 Neuroticism conditioned on average household income before tax (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals ? NR 2E-8 7.699 rs2279817 N/A neuroticism measurement (EFO:0007660)
 PMID:33349686
None Available GCST90027242 Neuroticism conditioned on highest math class (multi-trait conditioning and joint analysis) 170,911 European ancestry individuals ? NR 2E-8 7.699 rs2279817 N/A neuroticism measurement (EFO:0007660)
 PMID:33349686
Database Acc Id Source(s)
GWAS Catalog GCST003770 GWAS Catalog

RGD Curation Notes
Note Type Note Reference