GWAS613894_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS613894_H (neutrophil percentage of granulocytes QTL GWAS613894 (human)) Homo sapiens

Symbol: GWAS613894_H
Name: neutrophil percentage of granulocytes QTL GWAS613894 (human)
RGD ID: 406964918
Trait: neutrophil percentage of granulocytes
LOD Score: Not Available
P Value: 4.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3818,444,361 - 8,444,362RGD_MAPPER_PIPELINEGRCh38
GRCh3718,504,421 - 8,504,422RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS613894_HHumanneutrophil percentage of granulocytes  IAGPrs159963405850206 GWAS_CATALOGPMID:27863252
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1344336REREarginine-glutamic acid dipeptide repeats183524048817640Human

Position Markers

Peak: (rs159963)
Human AssemblyChrPosition (strand)Source
GRCh3818,444,361 - 8,444,362RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
407113060GWAS762036_Heosinophil count QTL GWAS762036 (human)6e-28eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)184443618444362Human
406969568GWAS618544_Heosinophil percentage of leukocytes QTL GWAS618544 (human)2e-19eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)184443618444362Human
407111366GWAS760342_Hrespiratory system disease QTL GWAS760342 (human)1e-11respiratory system disease184443618444362Human
407346469GWAS995445_Heosinophil count QTL GWAS995445 (human)7e-23eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)184443618444362Human
407345412GWAS994388_Hlymphocyte count QTL GWAS994388 (human)2e-11lymphocyte countblood lymphocyte count (CMO:0000031)184443618444362Human
407016583GWAS665559_Hunipolar depression QTL GWAS665559 (human)3e-08unipolar depression184443618444362Human
406966697GWAS615673_Heosinophil percentage of granulocytes QTL GWAS615673 (human)1e-16eosinophil percentage of granulocytes184443618444362Human
407053640GWAS702616_Heosinophil count QTL GWAS702616 (human)6e-17eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)184443618444362Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
406939725GWAS588701_Heosinophil percentage of leukocytes QTL GWAS588701 (human)2e-29eosinophil percentage of leukocytesblood eosinophil count to total leukocyte count ratio (CMO:0000369)184443618444362Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406954899GWAS603875_Heosinophil count QTL GWAS603875 (human)2e-12eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)184443618444362Human
406964918GWAS613894_Hneutrophil percentage of granulocytes QTL GWAS613894 (human)4e-16neutrophil percentage of granulocytes184443618444362Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS588701_H GCST90002382 Eosinophil percentage of white cells 408,112 British individuals A 0.58348 2E-29 28.699 rs159963 0.0254016 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:32888494
GWAS603875_H GCST004606 Eosinophil counts 172,275 European ancestry individuals A 0.5826 2E-12 11.699 rs159963 0.02564022 eosinophil count (EFO:0004842)
 PMID:27863252
GWAS613894_H GCST004623 Neutrophil percentage of granulocytes 170,672 European ancestry individuals A 0.5826 4E-16 15.398 rs159963 0.02967547 neutrophil percentage of granulocytes (EFO:0007994)
 PMID:27863252
GWAS615673_H GCST004617 Eosinophil percentage of granulocytes 170,536 European ancestry individuals A 0.5826 1E-16 16 rs159963 0.03014684 eosinophil percentage of granulocytes (EFO:0007996)
 PMID:27863252
GWAS618544_H GCST004600 Eosinophil percentage of white cells 172,378 European ancestry individuals A 0.5827 2E-19 18.699 rs159963 0.03283252 eosinophil percentage of leukocytes (EFO:0007991)
 PMID:27863252
GWAS702616_H GCST90002381 Eosinophil counts 408,112 British individuals A 0.583477 6E-17 16.222 rs159963 0.018836932 eosinophil count (EFO:0004842)
 PMID:32888494
GWAS760342_H GCST007076 Respiratory diseases approximately 459,000 European ancestry individuals ? NR 1E-11 11 rs159963 N/A respiratory system disease (EFO:0000684)
 PMID:30595370
GWAS762036_H GCST007065 Eosinophil counts approximately 440,000 European ancestry individuals ? NR 6E-28 27.222 rs159963 N/A eosinophil count (EFO:0004842)
 PMID:30595370
GWAS994388_H GCST90018962 Lymphocyte count 349,856 European ancestry individuals, 95,717 East Asian ancestry individuals A NR 2E-11 10.699 rs159963 0.015 lymphocyte count (EFO:0004587)
 PMID:34594039
GWAS995445_H GCST90018953 Eosinophil counts 349,856 European ancestry individuals, 93,063 East Asian ancestry individuals A NR 7E-23 22.155 rs159963 0.0169 eosinophil count (EFO:0004842)
 PMID:34594039
None Available GCST005839 Depression 135,458 European ancestry cases, 344,901 European ancestry controls C 0.44 3E-8 7.523 rs159963 1.0309278 PMID:29700475
Database Acc Id Source(s)
GWAS Catalog GCST004623 GWAS Catalog

RGD Curation Notes
Note Type Note Reference