GWAS608086_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS608086_H (ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis QTL GWAS608086 (human)) Homo sapiens

Symbol: GWAS608086_H
Name: ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis QTL GWAS608086 (human)
RGD ID: 406959110
Trait: ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis
LOD Score: Not Available
P Value: 5.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381538,606,989 - 38,606,990RGD_MAPPER_PIPELINEGRCh38
GRCh371538,899,190 - 38,899,191RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs16967103)
Human AssemblyChrPosition (strand)Source
GRCh381538,606,989 - 38,606,990RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
407222661GWAS871637_Hinsomnia QTL GWAS871637 (human)5e-12insomnia153860698938606990Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407305922GWAS954898_Hrheumatoid arthritis, hypothyroidism QTL GWAS954898 (human)3e-17rheumatoid arthritis, hypothyroidism153860698938606990Human
406959110GWAS608086_Hankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis QTL GWAS608086 (human)5e-09ankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis153860698938606990Human
407000360GWAS649336_HCrohn's disease QTL GWAS649336 (human)0.000001Crohn's disease153860698938606990Human
407059849GWAS708825_HCrohn's disease QTL GWAS708825 (human)4e-09Crohn's disease153860698938606990Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
407030639GWAS679615_Hinflammatory bowel disease QTL GWAS679615 (human)0.0000004inflammatory bowel disease153860698938606990Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS608086_H GCST005537 Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 8,726 European ancestry ankylosing spondylitis cases, 19,085 European ancestry Crohn’s disease cases, 6,530 European ancestry psoriasis cases, 3,408 European ancestry primary sclerosing cholangitis cases, 14,513 European ancestry ulcerative colitis cases, 34,213 European ancestry controls ? NR 5E-9 8.302 rs16967103 N/A ankylosing spondylitis (EFO:0003898)
psoriasis (EFO:0000676)
ulcerative colitis (EFO:0000729)
Crohn's disease (EFO:0000384)
More... 		PMID:26974007
GWAS649336_H GCST004132 Crohn's disease 12,194 European and unknown ancestry cases, 28,072 European and unknown ancestry controls ? NR 0.000001 6 rs16967103 N/A Crohn's disease (EFO:0000384)
 PMID:28067908
GWAS679615_H GCST003043 Inflammatory bowel disease 12,882 European ancestry cases, 21,770 European ancestry controls G 0.1937 4E-7 6.398 rs16967103 1.0664214 inflammatory bowel disease (EFO:0003767)
 PMID:26192919
GWAS708825_H GCST001729 Crohn's disease Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls C 0.203 4E-9 8.398 rs16967103 1.088 Crohn's disease (EFO:0000384)
 PMID:23128233
GWAS871637_H GCST90131903 Insomnia 390,751 European ancestry female cases, 1,018,386 European ancestry female controls T NR 5E-12 11.302 rs16967103 0.01 insomnia (EFO:0004698)
 PMID:35835914
GWAS954898_H GCST90428109 Hypothyroidism or rheumatoid arthritis (pleiotropy) 22,350 European ancestry rheumatoid arthritis cases, 51,194 European ancestry hypothyroidism cases, 518,206 European ancestry controls ? NR 3E-17 16.523 rs16967103 N/A rheumatoid arthritis (EFO:0000685)
hypothyroidism (EFO:0004705)
 PMID:38368726
Database Acc Id Source(s)
GWAS Catalog GCST005537 GWAS Catalog

RGD Curation Notes
Note Type Note Reference