GWAS607087_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL: GWAS607087_H (monocyte percentage of leukocytes QTL GWAS607087 (human)) Homo sapiens

Symbol: GWAS607087_H
Name: monocyte percentage of leukocytes QTL GWAS607087 (human)
RGD ID: 406958111
Trait: monocyte percentage of leukocytes
Measurement Type: blood monocyte count to total leukocyte count ratio   (CMO:0000374)    
LOD Score: Not Available
P Value: 1.0E-16
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381340,642,397 - 40,642,398RGD_MAPPER_PIPELINEGRCh38
GRCh371341,216,534 - 41,216,535RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS607087_HHumanblood monocyte count to total leukocyte count ratio  IAGPrs4325427405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS607087_HHumanmonocyte percentage of leukocytes  IAGPrs4325427405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
737155FOXO1forkhead box O1134055566740666641Human

Position Markers

Peak: (rs4325427)
Human AssemblyChrPosition (strand)Source
GRCh381340,642,397 - 40,642,398RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407231331GWAS880307_Hmonocyte count QTL GWAS880307 (human)2e-32monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)134064239740642398Human
406972967GWAS621943_Hmonocyte count QTL GWAS621943 (human)4e-15monocyte quantity (VT:0000223)blood monocyte count (CMO:0000032)134064239740642398Human
407062244GWAS711220_Hmonocyte percentage of leukocytes QTL GWAS711220 (human)3e-43monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)134064239740642398Human
406958171GWAS607147_Hgranulocyte percentage of myeloid white cells QTL GWAS607147 (human)3e-20granulocyte percentage of myeloid white cells134064239740642398Human
406958111GWAS607087_Hmonocyte percentage of leukocytes QTL GWAS607087 (human)1e-16monocyte percentage of leukocytesblood monocyte count to total leukocyte count ratio (CMO:0000374)134064239740642398Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS607087_H GCST004609 Monocyte percentage of white cells 170,494 European ancestry individuals T 0.2868 1E-16 16 rs4325427 0.03253815 monocyte percentage of leukocytes (EFO:0007989)
PMID:27863252
GWAS607147_H GCST004608 Granulocyte percentage of myeloid white cells 169,545 European ancestry individuals T 0.2868 3E-20 19.523 rs4325427 0.03641795 granulocyte percentage of myeloid white cells (EFO:0007997)
PMID:27863252
GWAS621943_H GCST004625 Monocyte count 170,721 European ancestry individuals T 0.2868 4E-15 14.398 rs4325427 0.03100491 monocyte count (EFO:0005091)
PMID:27863252
GWAS711220_H GCST90002394 Monocyte percentage of white cells 408,112 British individuals T 0.287155 3E-43 42.523 rs4325427 0.033687208 monocyte percentage of leukocytes (EFO:0007989)
PMID:32888494
GWAS880307_H GCST90002393 Monocyte count 408,112 British individuals T 0.287141 2E-32 31.699 rs4325427 0.028901674 monocyte count (EFO:0005091)
PMID:32888494
Database Acc Id Source(s)
GWAS Catalog GCST004609 GWAS Catalog

RGD Curation Notes
Note Type Note Reference