GWAS605826_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS605826_H (total cortical area measurement QTL GWAS605826 (human)) Homo sapiens

Symbol: GWAS605826_H
Name: total cortical area measurement QTL GWAS605826 (human)
RGD ID: 406956850
Trait: total cortical area measurement
LOD Score: Not Available
P Value: 2.0E-21
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381539,347,791 - 39,347,792RGD_MAPPER_PIPELINEGRCh38
GRCh371539,639,992 - 39,639,993RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS605826_HHumantotal cortical area measurement  IAGPrs4924346405850206 GWAS_CATALOGPMID:33875891
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
38627269LOC105370777uncharacterized LOC105370777153886480639421060Human

Position Markers

Peak: (rs4924346)
Human AssemblyChrPosition (strand)Source
GRCh381539,347,791 - 39,347,792RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
406956519GWAS605495_Hbrain volume measurement QTL GWAS605495 (human)6e-15brain volume measurementbrain morphological measurement (CMO:0000136)153934779139347792Human
406956838GWAS605814_Htotal cortical area measurement QTL GWAS605814 (human)2e-11total cortical area measurement153934779139347792Human
406956842GWAS605818_Htotal cortical area measurement QTL GWAS605818 (human)8e-27total cortical area measurement153934779139347792Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
406956850GWAS605826_Htotal cortical area measurement QTL GWAS605826 (human)2e-21total cortical area measurement153934779139347792Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406904245GWAS553221_Hcortical surface area measurement QTL GWAS553221 (human)1e-80cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934779139347792Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
407050936GWAS699912_Hcortical surface area measurement QTL GWAS699912 (human)5e-14cerebral cortex morphology trait (VT:0000788)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)153934779139347792Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS553221_H GCST010282 Cortical surface area 33,992 European ancestry individuals A 0.0902 1E-80 80 rs4924346 72.0821 cortical surface area measurement (EFO:0010736)
 PMID:32193296
GWAS605495_H GCST90002911 aparc-DKTatlas rh volume parstriangularis 21,281 British ancestry individuals A 0.089 6E-15 14.222 rs4924346 0.134 brain volume measurement (EFO:0006930)
 PMID:33875891
GWAS605814_H GCST90003398 aparc-a2009s rh area G-postcentral 21,282 British ancestry individuals A 0.089 2E-11 10.699 rs4924346 0.114 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS605818_H GCST90003300 aparc-a2009s lh area G+S-subcentral 21,282 British ancestry individuals A 0.089 8E-27 26.097 rs4924346 0.183 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS605826_H GCST90003285 aparc-DKTatlas rh area postcentral 21,282 British ancestry individuals A 0.089 2E-21 20.699 rs4924346 0.163 total cortical area measurement (EFO:0008381)
 PMID:33875891
GWAS699912_H GCST90271797 Parsopercularis area (unadjusted for global measures) 32,488 European ancestry individuals ? NR 5E-14 13.302 rs4924346 0.0926 cortical surface area measurement (EFO:0010736)
 PMID:36893272
Database Acc Id Source(s)
GWAS Catalog GCST90003285 GWAS Catalog

RGD Curation Notes
Note Type Note Reference