GWAS596027_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS596027_H (hemoglobin measurement QTL GWAS596027 (human)) Homo sapiens

Symbol: GWAS596027_H
Name: hemoglobin measurement QTL GWAS596027 (human)
RGD ID: 406947051
Trait: hemoglobin measurement
Measurement Type: hemoglobin measurement   (CMO:0000508)    
LOD Score: Not Available
P Value: 3.0E-30
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381667,777,687 - 67,777,688RGD_MAPPER_PIPELINEGRCh38
GRCh371667,811,590 - 67,811,591RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS596027_HHumanhemoglobin measurement  IAGPrs73591976405850206Based on the EFO term IDGWAS_CATALOGPMID:32888493

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS596027_HHumanhemoglobin measurement  IAGPrs73591976405850206 GWAS_CATALOGPMID:32888493
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1343804RANBP10RAN binding protein 10166772307067806560Human

Position Markers

Peak: (rs73591976)
Human AssemblyChrPosition (strand)Source
GRCh381667,777,687 - 67,777,688RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407140342GWAS789318_Hphospholipids in very large HDL measurement QTL GWAS789318 (human)3e-19phospholipids in very large HDL measurement 166777768767777688Human
406986160GWAS635136_Hhigh density lipoprotein cholesterol measurement QTL GWAS635136 (human)2e-14high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166777768767777688Human
407311236GWAS960212_Hhemoglobin measurement QTL GWAS960212 (human)1e-20hemoglobin measurementhemoglobin measurement (CMO:0000508)166777768767777688Human
406889431GWAS538407_Hhigh density lipoprotein cholesterol measurement QTL GWAS538407 (human)3e-38high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166777768767777688Human
406889432GWAS538408_Hhigh density lipoprotein cholesterol measurement QTL GWAS538408 (human)1e-45high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166777768767777688Human
406959032GWAS608008_Hhigh density lipoprotein cholesterol measurement QTL GWAS608008 (human)9e-26high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)166777768767777688Human
406947051GWAS596027_Hhemoglobin measurement QTL GWAS596027 (human)3e-30hemoglobin measurementhemoglobin measurement (CMO:0000508)166777768767777688Human
406935997GWAS584973_Hhematocrit QTL GWAS584973 (human)4e-27hematocrithematocrit (CMO:0000037)166777768767777688Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS538407_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C 0.886 3E-38 37.523 rs73591976 0.078 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS538408_H GCST007140 High density lipoprotein cholesterol levels 76,627 European ancestry individuals, 7,795 Hispanic individuals, 6,855 East Asian ancestry individuals, 2,958 African American individuals, 439 South Asian ancestry individuals C NR 1E-45 45 rs73591976 0.078 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:29507422
GWAS584973_H GCST90002304 Hematocrit 562,259 European ancestry individuals A 0.102153 4E-27 26.398 rs73591976 0.033474 hematocrit (EFO:0004348)
 PMID:32888493
GWAS596027_H GCST90002310 Hemoglobin concentration 563,946 European ancestry individuals A 0.10224 3E-30 29.523 rs73591976 0.035436 hemoglobin measurement (EFO:0004509)
 PMID:32888493
GWAS608008_H GCST002899 HDL cholesterol up to 62,166 European ancestry individuals A 0.12 9E-26 25.046 rs73591976 0.096 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:25961943
GWAS635136_H GCST008035 High density lipoprotein cholesterol levels 10,085 African American individuals, 17,751 Hispanic/Latino individuals, 2,378 Asian ancestry individuals, 1,912 Native Hawaiian ancestry individuals, 604 Native American ancestry individuals, 333 individuals ? NR 2E-14 13.699 rs73591976 1.183246 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:31217584
GWAS789318_H GCST90302134 Phospholipids in very large HDL 4,435 East Asian ancestry individuals, 11,340 South Asian ancestry individuals, 120,241 European ancestry individuals A 0.1241 3E-19 18.523 rs73591976 0.0559 phospholipids in very large HDL measurement (EFO:0022298)
 PMID:38448586
GWAS960212_H GCST90018957 Hemoglobin 350,474 European ancestry individuals, 152,447 East Asian ancestry individuals A NR 1E-20 20 rs73591976 0.0274 hemoglobin measurement (EFO:0004509)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST90002310 GWAS Catalog

RGD Curation Notes
Note Type Note Reference