GWAS594083_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS594083_H (ER membrane protein complex subunit 4 measurement QTL GWAS594083 (human)) Homo sapiens

Symbol: GWAS594083_H
Name: ER membrane protein complex subunit 4 measurement QTL GWAS594083 (human)
RGD ID: 406945107
Trait: ER membrane protein complex subunit 4 measurement
LOD Score: Not Available
P Value: 5E-947
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38196,698,416 - 6,698,417RGD_MAPPER_PIPELINEGRCh38
GRCh37196,698,427 - 6,698,428RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS594083_HHumanER membrane protein complex subunit 4 measurement  IAGPrs594974405850206 GWAS_CATALOGPMID:34648354
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
735504C3complement C31966777046720650Human

Position Markers

Peak: (rs594974)
Human AssemblyChrPosition (strand)Source
GRCh38196,698,416 - 6,698,417RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298499UAE1_HUrinary albumin excretion QTL 1 (human)2.730.0009Urinary albumin excretionurine albumin:creatinine ratio (ACR)19116075902Human
1643451SLIPL6_HSerum lipid level QTL 6 (human)2.190.0008Lipid level19116075902Human
406945107GWAS594083_HER membrane protein complex subunit 4 measurement QTL GWAS594083 (human)5e-947ER membrane protein complex subunit 4 measurement1966984166698417Human
1581534BP76_HBlood pressure QTL 76 (human)20.001Blood pressurepulse pressure19116075902Human
1581535BP65_HBlood pressure QTL 65 (human)3.10.001Blood pressurepulse pressure19116075902Human
2314591INSUL4_HInsulin level QTL 4 (human)3.80.000038Insulin levelfasting19116075902Human
1298476BP3_HBlood pressure QTL 3 (human)2.4Blood pressuresystolic19116075902Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS594083_H GCST90247444 ER membrane protein complex subunit 4 levels 10,708 European ancestry individuals A 0.76 5E-947 946.302 rs594974 0.857 ER membrane protein complex subunit 4 measurement (EFO:0801580)
 PMID:34648354
None Available GCST90448421 Baseline memory 880 African ancestry males ? NR 0.000005 5.302 rs594974 0.166497 memory performance (EFO:0004874)
 PMID:37984853
None Available GCST90448466 Memory decline x sex interaction 3,367 African ancestry individuals ? NR 0.000003 5.523 rs594974 0.024861 memory performance (EFO:0004874)
sex interaction measurement (EFO:0008343)
 PMID:37984853
Database Acc Id Source(s)
GWAS Catalog GCST90247444 GWAS Catalog

RGD Curation Notes
Note Type Note Reference