GWAS586146_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS586146_H (alkaline phosphatase measurement QTL GWAS586146 (human)) Homo sapiens

Symbol: GWAS586146_H
Name: alkaline phosphatase measurement QTL GWAS586146 (human)
RGD ID: 406937170
Trait: alkaline phosphatase measurement
Measurement Type: blood alkaline phosphatase activity level   (CMO:0000576)    
LOD Score: Not Available
P Value: 6.0E-52
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38121,576,457 - 21,576,458RGD_MAPPER_PIPELINEGRCh38
GRCh37121,902,950 - 21,902,951RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS586146_HHumanblood alkaline phosphatase activity level  IAGPrs1780329405850206Based on the EFO term IDGWAS_CATALOGPMID:31666285

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS586146_HHumanalkaline phosphatase measurement  IAGPrs1780329405850206 GWAS_CATALOGPMID:31666285
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1346147ALPLalkaline phosphatase, biomineralization associated12150898421578410Human

Position Markers

Peak: (rs1780329)
Human AssemblyChrPosition (strand)Source
GRCh38121,576,457 - 21,576,458RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406937170GWAS586146_Halkaline phosphatase measurement QTL GWAS586146 (human)6e-52alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)12157645721576458Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS586146_H GCST009652 Serum alkaline phosphatase levels 162,774 Icelandic ancestry individuals A 0.165 6E-52 51.222 rs1780329 0.08 alkaline phosphatase measurement (EFO:0004533)
 PMID:31666285
Database Acc Id Source(s)
GWAS Catalog GCST009652 GWAS Catalog

RGD Curation Notes
Note Type Note Reference