GWAS580579_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS580579_H (body height QTL GWAS580579 (human)) Homo sapiens

Symbol: GWAS580579_H
Name: body height QTL GWAS580579 (human)
RGD ID: 406931603
Trait: body height   (VT:0001253)    
Measurement Type: body height   (CMO:0000106)    
LOD Score: Not Available
P Value: 2.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381548,622,729 - 48,622,730RGD_MAPPER_PIPELINEGRCh38
GRCh371548,914,926 - 48,914,927RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS580579_HHumanbody height  IAGPrs1036477405850206Based on the EFO term IDGWAS_CATALOGPMID:37106081

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS580579_HHumanbody height  IAGPrs1036477405850206Based on the EFO term IDGWAS_CATALOGPMID:37106081

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS580579_HHumanbody height  IAGPrs1036477405850206 GWAS_CATALOGPMID:37106081
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement
body height  (IAGP)

Vertebrate Trait
body height  (IAGP)

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
731577FBN1fibrillin 1154840831348645709Human

Position Markers

Peak: (rs1036477)
Human AssemblyChrPosition (strand)Source
GRCh381548,622,729 - 48,622,730RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407290950GWAS939926_Haortic measurement QTL GWAS939926 (human)1e-16aortic measurementaorta measurement (CMO:0001474)154862272948622730Human
407000257GWAS649233_Hpulse pressure measurement QTL GWAS649233 (human)2e-26pulse pressure measurementpulse pressure (CMO:0000292)154862272948622730Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
407000874GWAS649850_Hsystolic blood pressure QTL GWAS649850 (human)0.0000002systolic blood pressuresystolic blood pressure (CMO:0000004)154862272948622730Human
407281837GWAS930813_Hascending aortic diameter QTL GWAS930813 (human)6e-15ascending aortic diameter154862272948622730Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
407002642GWAS651618_Hpulse pressure measurement QTL GWAS651618 (human)1e-09pulse pressure measurementpulse pressure (CMO:0000292)154862272948622730Human
407002643GWAS651619_Hpulse pressure measurement QTL GWAS651619 (human)2e-11pulse pressure measurementpulse pressure (CMO:0000292)154862272948622730Human
407292980GWAS941956_Haortic measurement QTL GWAS941956 (human)1e-12aortic measurementaorta measurement (CMO:0001474)154862272948622730Human
406931603GWAS580579_Hbody height QTL GWAS580579 (human)0.000002body height (VT:0001253)body height (CMO:0000106)154862272948622730Human
406972437GWAS621413_Hsystolic blood pressure QTL GWAS621413 (human)0.000004systolic blood pressuresystolic blood pressure (CMO:0000004)154862272948622730Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406929111GWAS578087_Hbody height QTL GWAS578087 (human)2e-14body height (VT:0001253)body height (CMO:0000106)154862272948622730Human
407320636GWAS969612_Haortic measurement QTL GWAS969612 (human)3e-17aortic measurementaorta measurement (CMO:0001474)154862272948622730Human
406910558GWAS559534_Hpulse pressure measurement QTL GWAS559534 (human)4e-08pulse pressure measurementpulse pressure (CMO:0000292)154862272948622730Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS559534_H GCST004775 Pulse pressure 150,134 European ancestry individuals G 0.103 4E-8 7.398 rs1036477 0.415 pulse pressure measurement (EFO:0005763)
 PMID:28739976
GWAS578087_H GCST90267284 Height (standard GWA) 283,749 European ancestry individuals G NR 2E-14 13.699 rs1036477 0.21883 body height (EFO:0004339)
 PMID:37106081
GWAS580579_H GCST90267285 Height (weighted GWA) 102,215 European ancestry individuals G NR 0.000002 5.699 rs1036477 0.24487 body height (EFO:0004339)
 PMID:37106081
GWAS621413_H GCST90269920 Childhood median systolic blood pressure percentile (13-18 years old) 5,133 Black or European ancestry individuals A 0.79 0.000004 5.398 rs1036477 3.85 systolic blood pressure (EFO:0006335)
 PMID:36718908
None Available GCST90267390 Ascending aorta diameter 38,372 European or unknown ancestry individuals A 0.895202 2E-14 13.699 rs1036477 0.0775709 ascending aortic diameter (EFO:0021787)
 PMID:37019578
GWAS649233_H GCST007096 Pulse pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals A NR 2E-26 25.699 rs1036477 0.418 pulse pressure measurement (EFO:0005763)
 PMID:27841878
GWAS649850_H GCST007099 Systolic blood pressure 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals A NR 2E-7 6.699 rs1036477 0.31 systolic blood pressure (EFO:0006335)
 PMID:27841878
GWAS651618_H GCST007097 Pulse pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals A NR 1E-9 9 rs1036477 0.325 pulse pressure measurement (EFO:0005763)
 PMID:27841878
GWAS651619_H GCST007097 Pulse pressure 80,792 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 7,243 East Asian ancestry individuals, 461 South Asian ancestry individuals A NR 2E-11 10.699 rs1036477 0.431 pulse pressure measurement (EFO:0005763)
 PMID:27841878
GWAS930813_H GCST90094402 Ascending thoracic aortic diameter 33,637 European ancestry individuals A 0.900757 6E-15 14.222 rs1036477 0.0870618 ascending aortic diameter (EFO:0021787)
 PMID:34837083
GWAS939926_H GCST90137450 Ascending aorta maximum area (MTAG) 32,590 European ancestry individuals A 0.9 1E-16 16 rs1036477 16.48 aortic measurement (EFO:0020865)
 PMID:35922433
GWAS941956_H GCST90137451 Descending aorta maximum area (MTAG) 32,590 European ancestry individuals A 0.9 1E-12 12 rs1036477 6.34 aortic measurement (EFO:0020865)
 PMID:35922433
GWAS969612_H GCST90137440 Ascending aorta maximum area 32,590 European ancestry individuals A 0.9 3E-17 16.523 rs1036477 16.72 aortic measurement (EFO:0020865)
 PMID:35922433
Database Acc Id Source(s)
GWAS Catalog GCST90267285 GWAS Catalog

RGD Curation Notes
Note Type Note Reference