GWAS574238_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS574238_H (psoriatic arthritis QTL GWAS574238 (human)) Homo sapiens

Symbol: GWAS574238_H
Name: psoriatic arthritis QTL GWAS574238 (human)
RGD ID: 406925262
Trait: psoriatic arthritis
LOD Score: Not Available
P Value: 9.0E-6
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38124,970,693 - 24,970,694RGD_MAPPER_PIPELINEGRCh38
GRCh37125,297,184 - 25,297,185RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS574238_HHumanpsoriatic arthritis  IAGPrs11249215405850206 GWAS_CATALOGPMID:30552173
Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Position Markers

Peak: (rs11249215)
Human AssemblyChrPosition (strand)Source
GRCh38124,970,693 - 24,970,694RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298451OSTEAR17_HOsteoarthritis QTL 17 (human)2.40.0004Joint/bone inflammationosteoarthritis11125188105Human
1576329MYI9_HMyocardial infarction susceptibility QTL 9 (human)12Myocardial infarction susceptibilityearly-onset1758550333585503Human
406924306GWAS573282_Hpsoriasis, type 2 diabetes mellitus QTL GWAS573282 (human)7e-14psoriasis, type 2 diabetes mellitus12497069324970694Human
407275421GWAS924397_Hbody height QTL GWAS924397 (human)1e-32body height (VT:0001253)body height (CMO:0000106)12497069324970694Human
1298463BP9_HBlood pressure QTL 9 (human)3.9Blood pressurehypertension susceptibility1125188105Human
406907612GWAS556588_HCrohn's disease QTL GWAS556588 (human)8e-11Crohn's disease12497069324970694Human
1576325MYI1_HMyocardial infarction susceptibility QTL 1 (human)11.681e-12Myocardial infarction susceptibilityearly-onset1758550333585503Human
1643380BW316_HBody weight QTL 316 (human)2.620.0002Body weightBMI1758550333585503Human
406910686GWAS559662_Hankylosing spondylitis QTL GWAS559662 (human)9e-11ankylosing spondylitis12497069324970694Human
406925262GWAS574238_Hpsoriatic arthritis QTL GWAS574238 (human)0.000009psoriatic arthritis12497069324970694Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS556588_H GCST90319897 Crohn's disease 2,523 Korean ancestry cases, 76,598 Korean ancestry controls A 0.545 8E-11 10.097 rs11249215 0.79 Crohn's disease (EFO:0000384)
 PMID:37523193
GWAS559662_H GCST001149 Ankylosing spondylitis 3,023 European ancestry cases, 8,779 European ancestry controls A 0.47 9E-11 10.046 rs11249215 N/A ankylosing spondylitis (EFO:0003898)
 PMID:21743469
GWAS573282_H GCST011991 Psoriasis or type 2 diabetes (trans-disease meta-analysis) 11,024 European ancestry psoriasis cases, 74,124 European ancestry diabetes cases, 840,342 European ancestry controls A NR 7E-14 13.155 rs11249215 1.08 psoriasis (EFO:0000676)
 PMID:33385400
GWAS574238_H GCST007043 Psoriatic arthritis 744 Spanish ancestry cases, 1,454 Spanish ancestry controls ? NR 0.000009 5.046 rs11249215 4.44 psoriatic arthritis (EFO:0003778)
 PMID:30552173
GWAS924397_H GCST90245848 Height 5,314,291 European ancestry, Hispanic or Latin American, East Asian ancestry, African ancestry, South Asian ancestry individuals A 0.4749 1E-32 32 rs11249215 0.0107 body height (EFO:0004339)
 PMID:36224396
Database Acc Id Source(s)
GWAS Catalog GCST007043 GWAS Catalog

RGD Curation Notes
Note Type Note Reference