GWAS567571_H QTL Report (Homo sapiens) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: GWAS567571_H (low density lipoprotein cholesterol measurement QTL GWAS567571 (human)) Homo sapiens

Symbol: GWAS567571_H
Name: low density lipoprotein cholesterol measurement QTL GWAS567571 (human)
RGD ID: 406918595
Trait: low density lipoprotein cholesterol measurement
Measurement Type: blood low density lipoprotein cholesterol level   (CMO:0000053)    
LOD Score: Not Available
P Value: 8.0E-9
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh387137,875,053 - 137,875,054RGD_MAPPER_PIPELINEGRCh38
GRCh377137,559,799 - 137,559,800RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model




Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS567571_HHumanblood low density lipoprotein cholesterol level  IAGPrs73729083405850206Based on the EFO term IDGWAS_CATALOGPMID:30926973

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GWAS567571_HHumanlow density lipoprotein cholesterol measurement  IAGPrs73729083405850206 GWAS_CATALOGPMID:30926973

#
Reference Title
Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records


The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1314429CREB3L2cAMP responsive element binding protein 3 like 27137874979138002086Human


Peak: (rs73729083)
Human AssemblyChrPosition (strand)Source
GRCh387137,875,053 - 137,875,054RGD_MAPPER_PIPELINE


1 to 10 of 14 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
407095619GWAS744595_Hlow density lipoprotein cholesterol measurement QTL GWAS744595 (human)9e-08low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
406918595GWAS567571_Hlow density lipoprotein cholesterol measurement QTL GWAS567571 (human)8e-09low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
597027191GWAS1123265_Hlow density lipoprotein cholesterol measurement QTL GWAS1123265 (human)8e-08low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
597032881GWAS1128955_Hlow density lipoprotein cholesterol measurement QTL GWAS1128955 (human)0.000004low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
597032880GWAS1128954_Hlow density lipoprotein cholesterol measurement QTL GWAS1128954 (human)0.000001low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
407095556GWAS744532_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS744532 (human)8e-15low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
597032869GWAS1128943_Hsmoking status measurement, low density lipoprotein cholesterol measurement QTL GWAS1128943 (human)1e-14smoking status measurement, low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human
597140039GWAS1236113_Htotal cholesterol measurement QTL GWAS1236113 (human)0.0000008total cholesterol measurementblood total cholesterol level (CMO:0000051)7137875053137875054Human
597342795GWAS1438869_Hhigh density lipoprotein cholesterol measurement QTL GWAS1438869 (human)4e-13high density lipoprotein cholesterol measurementblood high density lipoprotein cholesterol level (CMO:0000052)7137875053137875054Human
407085201GWAS734177_Hlow density lipoprotein cholesterol measurement, alcohol drinking QTL GWAS734177 (human)3e-10low density lipoprotein cholesterol measurement, alcohol drinkingblood low density lipoprotein cholesterol level (CMO:0000053)7137875053137875054Human

1 to 10 of 14 rows


1 to 16 of 16 rows
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL
GWAS Catalog Study
Disease Trait
Study Size
Risk Allele
Risk Allele Frequency
P Value
P Value MLOG
Peak Marker
Reported Odds Ratio or Beta-coefficient
Ontology Accession
PubMed
GWAS567571_H GCST008676 LDL cholesterol levels up to 23,353 African ancestry individuals, 13,171 Asian ancestry individuals, up to 82,522 European ancestry individuals, 6,646 Hispanic individuals ? NR 8E-9 8.097 rs73729083 3.5283 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1123265_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 8E-8 7.097 rs73729083 3.668 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1123340_H GCST008086 LDL cholesterol levels in current drinkers 56,505 European ancestry individuals, 9,870 African American individuals, 2,491 Asian ancestry individuals, 2,528 Hispanic individuals C NR 6E-7 6.222 rs73729083 3.861 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1128917_H GCST008687 LDL cholesterol levels x smoking (current vs non smokers) interaction (2df test) 4,973 African ancestry current smoker individuals, 2,375 Asian ancestry current smoker individuals, 13,799 European ancestry current smoker individuals, 755 Hispanic current smoker individuals, 18,384 African ancestry non smoker individuals, 10,742 Asian ancestry non smoker individuals, 68,719 European ancestry non smoker individuals, 5,894 Hispanic non smoker individuals C 0.05 1E-9 9 rs73729083 N/A smoking status measurement (EFO:0006527)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1128941_H GCST008691 LDL cholesterol levels x smoking (ever vs never smokers) interaction (2df test) 11,649 African ancestry ever smoker individuals, 3,999 Asian ancestry ever smoker individuals, 45,506 European ancestry ever smoker individuals, 2,554 Hispanic ever smoker individuals, 11,700 African ancestry never smoker individuals, 9,118 Asian ancestry never smoker individuals, 37,016 European ancestry never smoker individuals, 4,095 Hispanic never smoker individuals ? NR 6E-10 9.222 rs73729083 0.6317 smoking status measurement (EFO:0006527)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1128943_H GCST008691 LDL cholesterol levels x smoking (ever vs never smokers) interaction (2df test) 11,649 African ancestry ever smoker individuals, 3,999 Asian ancestry ever smoker individuals, 45,506 European ancestry ever smoker individuals, 2,554 Hispanic ever smoker individuals, 11,700 African ancestry never smoker individuals, 9,118 Asian ancestry never smoker individuals, 37,016 European ancestry never smoker individuals, 4,095 Hispanic never smoker individuals C 0.05 1E-14 14 rs73729083 0.37 smoking status measurement (EFO:0006527)
low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1128954_H GCST008692 LDL cholesterol levels in ever smokers 11,649 African ancestry individuals, 3,999 Asian ancestry individuals, 45,506 European ancestry individuals, 2,554 Hispanic individuals ? NR 0.000001 6 rs73729083 4.2549 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1128955_H GCST008693 LDL cholesterol levels in never smokers 11,700 African ancestry individuals, 9,118 Asian ancestry individuals, 37,016 European ancestry individuals, 4,095 Hispanic individuals ? NR 0.000004 5.398 rs73729083 3.6737 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30926973
GWAS1713624_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 3E-7 6.523 rs73729083 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS1713936_H GCST008078 LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) 44,831 European ancestry regular drinkers, 3,976 African American regular drinkers, 1,288 Asian ancestry regular drinkers, 827 Hispanic regular drinkers, 11,674 European ancestry non-regular drinkers, 5,894 African American non-regular drinkers, 1,203 Asian ancestry non-regular drinkers, 1,701 Hispanic non-regular drinkers C NR 2E-9 8.699 rs73729083 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol consumption quality (OBA:1000840)
 PMID:30698716
GWAS731885_H GCST008077 LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 0.000002 5.699 rs73729083 4.197 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS734177_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 3E-10 9.523 rs73729083 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS744532_H GCST008079 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) 56,505 European ancestry current drinkers, 9,870 African American current drinkers, 2,491 Asian ancestry current drinkers, 2,528 Hispanic current drinkers, 33,388 European ancestry non-drinkers, 11,119 African American non-drinkers, 9,959 Asian ancestry non-drinkers, 1,466 Hispanic non-drinkers C NR 8E-15 14.097 rs73729083 N/A low density lipoprotein cholesterol measurement (EFO:0004611)
alcohol drinking (EFO:0004329)
 PMID:30698716
GWAS744595_H GCST008077 LDL cholesterol levels 89,893 European ancestry individuals, 20,989 African American individuals, 12,450 Asian ancestry individuals, 3,994 HIspanic individuals C NR 9E-8 7.046 rs73729083 4.009 low density lipoprotein cholesterol measurement (EFO:0004611)
 PMID:30698716
GWAS1236113_H GCST90244655 Total cholesterol levels 29,502 European ancestry individuals, 16,983 Black individuals, 13,943 Hispanic individuals, 4,719 Asian ancestry individuals, 1,182 Samoan ancestry individuals ? NR 8E-7 6.097 rs73729083 3.538 total cholesterol measurement (EFO:0004574)
 PMID:36220816
GWAS1438869_H GCST90292527 High-density lipoprotein levels (MTAG) 125,000 African ancestry individuals (MTAG boosted by total cholesterol and triglyceride samples) C NR 4E-13 12.398 rs73729083 0.026 high density lipoprotein cholesterol measurement (EFO:0004612)
 PMID:37669986
1 to 16 of 16 rows
Database
Acc Id
Source(s)
GWAS Catalog GCST008676 GWAS Catalog

Note Type Note Reference