GWAS554151_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS554151_H (sex hormone-binding globulin measurement QTL GWAS554151 (human)) Homo sapiens

Symbol: GWAS554151_H
Name: sex hormone-binding globulin measurement QTL GWAS554151 (human)
RGD ID: 406905175
Trait: sex hormone-binding globulin measurement
LOD Score: Not Available
P Value: 1.0E-8
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381560,616,108 - 60,616,109RGD_MAPPER_PIPELINEGRCh38
GRCh371560,908,307 - 60,908,308RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS554151_HHumansex hormone-binding globulin measurement  IAGPrs340025405850206 GWAS_CATALOGPMID:33980691
References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
9681205RORA-AS1RORA antisense RNA 1156047917860630639Human
1318175RORARAR related orphan receptor A156048828461229302Human

Position Markers

Peak: (rs340025)
Human AssemblyChrPosition (strand)Source
GRCh381560,616,108 - 60,616,109RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406903905GWAS552881_Hserum alanine aminotransferase measurement QTL GWAS552881 (human)6e-19serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)156061610860616109Human
406899553GWAS548529_Htotal cholesterol measurement, C-reactive protein measurement QTL GWAS548529 (human)3e-10body mass indexbody mass index (BMI) (CMO:0000105)156061610860616109Human
406905252GWAS554228_Hbody fat percentage QTL GWAS554228 (human)5e-09body fat percentagebody fat percentage (CMO:0000302)156061610860616109Human
406891700GWAS540676_Hbody mass index QTL GWAS540676 (human)2e-10body mass indexbody mass index (BMI) (CMO:0000105)156061610860616109Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406905175GWAS554151_Hsex hormone-binding globulin measurement QTL GWAS554151 (human)1e-08sex hormone-binding globulin measurement156061610860616109Human
406936537GWAS585513_Hbody mass index QTL GWAS585513 (human)5e-14body mass indexbody mass index (BMI) (CMO:0000105)156061610860616109Human
406903913GWAS552889_Haspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement QTL GWAS552889 (human)7e-13aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurementblood high density lipoprotein cholesterol level (CMO:0000052)156061610860616109Human
406886842GWAS535818_Hbody mass index QTL GWAS535818 (human)1e-14body mass indexbody mass index (BMI) (CMO:0000105)156061610860616109Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
406903901GWAS552877_Haspartate aminotransferase measurement QTL GWAS552877 (human)0.0000001aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)156061610860616109Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS535818_H GCST009004 Body mass index 806,834 European ancestry individuals T 0.4081 1E-14 14 rs340025 0.0127 body mass index (EFO:0004340)
 PMID:30239722
None Available GCST009003 Body mass index 434,794 European ancestry female individuals T 0.4081 1E-14 14 rs340025 0.0127 body mass index (EFO:0004340)
 PMID:30239722
GWAS540676_H GCST009871 Body mass index 457,822 European ancestry individuals ? NR 2E-10 9.699 rs340025 N/A body mass index (EFO:0004340)
 PMID:31669095
GWAS548529_H GCST003678 C-reactive protein levels or total cholesterol levels (pleiotropy) 65,000 individuals (C-reactive protein), 100,184 individuals (total cholesterol) T NR 3E-10 9.523 rs340025 N/A total cholesterol measurement (EFO:0004574)
C-reactive protein measurement (EFO:0004458)
 PMID:27286809
GWAS552877_H GCST90020237 Aspartate aminotransferase levels 424,778 European ancestry individuals C 0.58 1E-7 7 rs340025 0.01 aspartate aminotransferase measurement (EFO:0004736)
 PMID:33980691
GWAS552881_H GCST90020236 Alanine aminotransferase levels 429,203 European ancestry individuals C 0.58 6E-19 18.222 rs340025 0.017 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:33980691
GWAS552889_H GCST90038594 Metabolic biomarkers (multivariate analysis) 389,354 European ancestry individuals C 0.58 7E-13 12.155 rs340025 N/A aspartate aminotransferase measurement (EFO:0004736)
serum alanine aminotransferase measurement (EFO:0004735)
low density lipoprotein triglyceride measurement (EFO:0009946)
body fat percentage (EFO:0007800)
More... 		PMID:33980691
GWAS554151_H GCST90020234 Sex hormone-binding globulin levels 389,354 European ancestry individuals C 0.58 1E-8 8 rs340025 0.01 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:33980691
GWAS554228_H GCST90020232 Body fat percentage 442,278 European ancestry individuals C 0.58 5E-9 8.302 rs340025 0.009 body fat percentage (EFO:0007800)
 PMID:33980691
None Available GCST90301650 Body mass index 441,761 European ancestry individuals T NR 3E-10 9.523 rs340025 0.0123413 body mass index (EFO:0004340)
 PMID:37280435
GWAS585513_H GCST90179150 Body mass index (MTAG) 694,649 European ancestry individuals T NR 5E-14 13.302 rs340025 0.01227 body mass index (EFO:0004340)
 PMID:36376304
Database Acc Id Source(s)
GWAS Catalog GCST90020234 GWAS Catalog

RGD Curation Notes
Note Type Note Reference