GWAS548289_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS548289_H (diastolic blood pressure, systolic blood pressure QTL GWAS548289 (human)) Homo sapiens

Symbol: GWAS548289_H
Name: diastolic blood pressure, systolic blood pressure QTL GWAS548289 (human)
RGD ID: 406899313
Trait: diastolic blood pressure, systolic blood pressure
Measurement Type: diastolic blood pressure   (CMO:0000005)    
systolic blood pressure   (CMO:0000004)    
LOD Score: Not Available
P Value: 5.0E-11
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381540,352,897 - 40,352,898RGD_MAPPER_PIPELINEGRCh38
GRCh371540,645,098 - 40,645,099RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS548289_HHumandiastolic blood pressure  IAGPrs7164581405850206Based on the EFO term IDGWAS_CATALOGPMID:34989438
GWAS548289_HHumansystolic blood pressure  IAGPrs7164581405850206Based on the EFO term IDGWAS_CATALOGPMID:34989438

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS548289_HHumandiastolic blood pressure  IAGPrs7164581405850206 GWAS_CATALOGPMID:34989438
GWAS548289_HHumansystolic blood pressure  IAGPrs7164581405850206 GWAS_CATALOGPMID:34989438
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
3398935PHGR1proline, histidine and glycine rich 1154035103340356434Human

Position Markers

Peak: (rs7164581)
Human AssemblyChrPosition (strand)Source
GRCh381540,352,897 - 40,352,898RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2289410BW327_HBody weight QTL 327 (human)3.320.0001Body fat amount151998012945980129Human
1643273BW330_HBody Weight QTL 330 (human)1.050.014Body weightbody mass index152686671952866719Human
406899313GWAS548289_Hdiastolic blood pressure, systolic blood pressure QTL GWAS548289 (human)5e-11diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)154035289740352898Human
2289430BMD7_HBone mineral density QTL 7 (human)3.320.0001Bone mineral density151998012945980129Human
1559411SCL107_HSerum cholesterol level QTL 107 (human)3.88Lipid leveltriglyceride152654355252543552Human
2299958PRSTS330_HProstate tumor susceptibility QTL 330 (human)1.020.0151Prostate tumor susceptibility153479023060790230Human
406907737GWAS556713_Hdiastolic blood pressure, systolic blood pressure QTL GWAS556713 (human)2e-10diastolic blood pressure, systolic blood pressuresystolic blood pressure (CMO:0000004)154035289740352898Human
1643523BW284_HBody Weight QTL 284 (human)1.950.0013Body weight152179288947792889Human
1559354LDLPS4_HLow density lipoprotein particle size QTL 4 (human)2.20.019LDL particle size153479023060790230Human
2289420BW314_HBody weight QTL 314 (human)2.720.0003Body weightlean mass151998012945980129Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS548289_H GCST90239828 Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 5E-11 10.302 rs7164581 N/A diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
GWAS556713_H GCST90239829 Blood pressure (pleiotropy model 2 SBP adjusted for estimated causal effects x DBP) 757,601 European ancestry individuals, 318,891 European ancestry, African American or Afro-Caribbean, Native American ancestry, Asian ancestry individuals ? NR 2E-10 9.699 rs7164581 N/A diastolic blood pressure (EFO:0006336)
systolic blood pressure (EFO:0006335)
 PMID:34989438
Database Acc Id Source(s)
GWAS Catalog GCST90239828 GWAS Catalog

RGD Curation Notes
Note Type Note Reference