GWAS546158_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS546158_H (reticulocyte count QTL GWAS546158 (human)) Homo sapiens

Symbol: GWAS546158_H
Name: reticulocyte count QTL GWAS546158 (human)
RGD ID: 406897182
Trait: reticulocyte count
Measurement Type: total reticulocyte count   (CMO:0003020)    
LOD Score: Not Available
P Value: 4.0E-18
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38358,051,208 - 58,051,209RGD_MAPPER_PIPELINEGRCh38
GRCh37358,036,935 - 58,036,936RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS546158_HHumantotal reticulocyte count  IAGPrs732527405850206Based on the EFO term IDGWAS_CATALOGPMID:27863252

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS546158_HHumanreticulocyte count  IAGPrs732527405850206 GWAS_CATALOGPMID:27863252
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1323621FLNBfilamin B35800842258172251Human

Position Markers

Peak: (rs732527)
Human AssemblyChrPosition (strand)Source
GRCh38358,051,208 - 58,051,209RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298487BFD1_HBody fluid distribution QTL 1 (human)3.94Body fluid distributionimpedance ratio33638071262380712Human
406967812GWAS616788_Hreticulocyte count QTL GWAS616788 (human)9e-19reticulocyte counttotal reticulocyte count (CMO:0003020)35805120858051209Human
1298489RA4_HRheumatoid arthritis QTL 4 (human)0.0283Joint/bone inflammationrheumatoid arthritis33638071262380712Human
1643509BW293_HBody Weight QTL 293 (human)1.42Body weightBMI33638071262380712Human
406975165GWAS624141_Hreticulocyte count QTL GWAS624141 (human)1e-16reticulocyte counttotal reticulocyte count (CMO:0003020)35805120858051209Human
2289308BW392_HBody weight QTL 392 (human)1.42Body weightBMI33638071262380712Human
406897182GWAS546158_Hreticulocyte count QTL GWAS546158 (human)4e-18reticulocyte counttotal reticulocyte count (CMO:0003020)35805120858051209Human
1331643COPD16_HChronic obstructive pulmonary disease QTL 16 (human)1.07Chronic airflow obstructionpost-BD FEV1 minus pre-BD FEV1/pre-BD FEV1 x 10034938065175380651Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS546158_H GCST004611 High light scatter reticulocyte count 170,761 European ancestry individuals C 0.3585 4E-18 17.398 rs732527 0.0327628 reticulocyte count (EFO:0007986)
 PMID:27863252
GWAS616788_H GCST004612 High light scatter reticulocyte percentage of red cells 170,763 European ancestry individuals C 0.3585 9E-19 18.046 rs732527 0.0333776 reticulocyte count (EFO:0007986)
 PMID:27863252
GWAS624141_H GCST004628 Immature fraction of reticulocytes 170,548 European ancestry individuals C 0.3585 1E-16 16 rs732527 0.03087325 reticulocyte count (EFO:0007986)
 PMID:27863252
Database Acc Id Source(s)
GWAS Catalog GCST004611 GWAS Catalog

RGD Curation Notes
Note Type Note Reference