GWAS537868_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS537868_H (birth weight QTL GWAS537868 (human)) Homo sapiens

Symbol: GWAS537868_H
Name: birth weight QTL GWAS537868 (human)
RGD ID: 406888892
Trait: birth weight
Measurement Type: neonatal body weight   (CMO:0002079)    
LOD Score: Not Available
P Value: 2.0E-33
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh381265,958,046 - 65,958,047RGD_MAPPER_PIPELINEGRCh38
GRCh371266,351,826 - 66,351,827RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS537868_HHumanneonatal body weight  IAGPrs1351394405850206Based on the EFO term IDGWAS_CATALOGPMID:27680694

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS537868_HHumanbirth weight  IAGPrs1351394405850206 GWAS_CATALOGPMID:27680694
Disease Annotations     Click to see Annotation Detail View
Birth Weight  (IAGP)

Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
1348013HMGA2high mobility group AT-hook 2126582446065966291Human

Position Markers

Peak: (rs1351394)
Human AssemblyChrPosition (strand)Source
GRCh381265,958,046 - 65,958,047RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407040834GWAS689810_Hhip circumference QTL GWAS689810 (human)4e-08hip circumferencehip circumference (CMO:0000014)126595804665958047Human
406949185GWAS598161_HBMI-adjusted hip circumference QTL GWAS598161 (human)0.0000008BMI-adjusted hip circumferencehip circumference (CMO:0000014)126595804665958047Human
407059808GWAS708784_Hbody height QTL GWAS708784 (human)2e-65body height (VT:0001253)body height (CMO:0000106)126595804665958047Human
407205632GWAS854608_Hinsulin measurement QTL GWAS854608 (human)3e-09pulse pressure measurementpulse pressure (CMO:0000292)126595804665958047Human
407337612GWAS986588_HBMI-adjusted hip circumference QTL GWAS986588 (human)3e-15BMI-adjusted hip circumferencehip circumference (CMO:0000014)126595804665958047Human
406999055GWAS648031_Hsex hormone-binding globulin measurement QTL GWAS648031 (human)6e-08sex hormone-binding globulin measurement126595804665958047Human
407307048GWAS956024_Hlean body mass QTL GWAS956024 (human)3e-85body lean mass (VT:0010483)total body lean mass (CMO:0003950)126595804665958047Human
406986797GWAS635773_Hsex hormone-binding globulin measurement QTL GWAS635773 (human)4e-11sex hormone-binding globulin measurement126595804665958047Human
407042034GWAS691010_Hhip circumference QTL GWAS691010 (human)6e-11hip circumferencehip circumference (CMO:0000014)126595804665958047Human
406921008GWAS569984_Htriglyceride measurement QTL GWAS569984 (human)5e-11triglyceride measurementblood triglyceride level (CMO:0000118)126595804665958047Human
407336502GWAS985478_Htriglyceride measurement QTL GWAS985478 (human)5e-09triglyceride measurementblood triglyceride level (CMO:0000118)126595804665958047Human
406948659GWAS597635_HBMI-adjusted hip circumference QTL GWAS597635 (human)5e-13BMI-adjusted hip circumferencehip circumference (CMO:0000014)126595804665958047Human
406966322GWAS615298_Hbody height at birth QTL GWAS615298 (human)0.0000007body height at birthbody height (CMO:0000106)126595804665958047Human
406995574GWAS644550_Hbody height QTL GWAS644550 (human)1e-11body height (VT:0001253)body height (CMO:0000106)126595804665958047Human
406888892GWAS537868_Hbirth weight QTL GWAS537868 (human)2e-33birth weightneonatal body weight (CMO:0002079)126595804665958047Human
406894909GWAS543885_Hbody surface area QTL GWAS543885 (human)1e-72body surface area126595804665958047Human
407022812GWAS671788_Hbody height QTL GWAS671788 (human)7e-32body height (VT:0001253)body height (CMO:0000106)126595804665958047Human
406949407GWAS598383_HBMI-adjusted hip circumference QTL GWAS598383 (human)2e-08BMI-adjusted hip circumferencehip circumference (CMO:0000014)126595804665958047Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS537868_H GCST005146 Birth weight 133,903 European ancestry individuals, 6,635 African American individuals, 420 Turkish ancestry individuals, 365 Moroccan ancestry individuals, 395 Surinamese ancestry individuals, 840 Chinese ancestry individuals. T 0.48 2E-33 32.699 rs1351394 0.043 birth weight (EFO:0004344)
 PMID:27680694
GWAS543885_H GCST90245995 Body surface area 337,198 British ancestry individuals ? NR 1E-72 72 rs1351394 0.00723972 body surface area (EFO:0022196)
 PMID:36502284
GWAS569984_H GCST010244 Triglyceride levels 441,016 European ancestry individuals T 0.488178 5E-11 10.302 rs1351394 0.013086 triglyceride measurement (EFO:0004530)
 PMID:32203549
GWAS597635_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.4952 5E-13 12.302 rs1351394 0.0253 BMI-adjusted hip circumference (EFO:0008039)
 PMID:25673412
GWAS598161_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.4952 8E-7 6.097 rs1351394 0.0222 BMI-adjusted hip circumference (EFO:0008039)
 PMID:25673412
GWAS598383_H GCST004067 Hip circumference adjusted for BMI up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.4952 2E-8 7.699 rs1351394 0.0281 BMI-adjusted hip circumference (EFO:0008039)
 PMID:25673412
GWAS615298_H GCST002644 Birth length 28,459 European ancestry individuals T 0.498 7E-7 6.155 rs1351394 0.044 body height at birth (EFO:0006784)
 PMID:25281659
GWAS635773_H GCST90012108 Sex hormone-binding globulin levels adjusted for BMI 180,094 European ancestry men T 0.490619 4E-11 10.398 rs1351394 0.00790807 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS644550_H GCST008053 Height 17,286 African American individuals, 22,192 Hispanic/Latino individuals, 4,680 Asian ancestry individuals, 3,939 Native Hawaiian ancestry individuals, 647 Native American ancestry individuals, 1,052 individuals ? NR 1E-11 11 rs1351394 0.04059133 body height (EFO:0004339)
 PMID:31217584
GWAS648031_H GCST90012109 Sex hormone-binding globulin levels 180,726 European ancestry men T 0.490619 6E-8 7.222 rs1351394 0.00690505 sex hormone-binding globulin measurement (EFO:0004696)
 PMID:32042192
GWAS671788_H GCST001956 Height 8,097 European ancestry tall individuals, 8,099 European ancestry short individuals T 0.49 7E-32 31.155 rs1351394 1.26 body height (EFO:0004339)
 PMID:23563607
GWAS689810_H GCST004066 Hip circumference up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.4952 4E-8 7.398 rs1351394 0.0267 hip circumference (EFO:0005093)
 PMID:25673412
GWAS691010_H GCST004066 Hip circumference up to 56,910 European ancestry men, up to 86,570 European ancestry women T 0.4952 6E-11 10.222 rs1351394 0.0229 hip circumference (EFO:0005093)
 PMID:25673412
GWAS708784_H GCST000817 Height 133,653 European ancestry individuals T 0.49 2E-65 64.699 rs1351394 0.06 body height (EFO:0004339)
 PMID:20881960
GWAS854608_H GCST90002238 Fasting insulin 151,013 European ancestry individuals T 0.4943 3E-9 8.523 rs1351394 0.0111 insulin measurement (EFO:0004467)
 PMID:34059833
GWAS956024_H GCST90428120 Whole body fat free mass (UKB data field 23101) 337,739 European ancestry individuals C NR 3E-85 84.523 rs1351394 0.025831 lean body mass (EFO:0004995)
 PMID:38538606
GWAS985478_H GCST90018975 Triglycerides 343,992 European ancestry individuals, 111,667 East Asian ancestry individuals C NR 5E-9 8.302 rs1351394 0.0136 triglyceride measurement (EFO:0004530)
 PMID:34594039
GWAS986588_H GCST90020026 Hip index 219,872 British ancestry women T NR 3E-15 14.523 rs1351394 0.0231125 BMI-adjusted hip circumference (EFO:0008039)
 PMID:34021172
None Available GCST90018970 Pulse pressure 360,863 European ancestry individuals, 145,445 East Asian ancestry individuals C NR 3E-9 8.523 rs1351394 0.0127 pulse pressure measurement (EFO:0005763)
 PMID:34594039
Database Acc Id Source(s)
GWAS Catalog GCST005146 GWAS Catalog

RGD Curation Notes
Note Type Note Reference