Clcc1 (chloride channel CLIC-like 1) - Rat Genome Database

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Gene: Clcc1 (chloride channel CLIC-like 1) Rattus norvegicus
Analyze
Symbol: Clcc1
Name: chloride channel CLIC-like 1
RGD ID: 708359
Description: Enables chloride channel activity. Involved in chloride transport. Located in Golgi apparatus; endoplasmic reticulum; and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 32. Orthologous to human CLCC1 (chloride channel CLIC like 1); INTERACTS WITH 2,6-dinitrotoluene; 3,4-methylenedioxymethamphetamine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: chloride channel CLIC-like protein 1; ER anion channel 1; ERAC1; LOC170927; Mclc; Mid-1-related chloride channel 1; mid-1-related chloride channel protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,984,455 - 199,015,015 (+)NCBIGRCr8
mRatBN7.22196,296,350 - 196,326,914 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,296,393 - 196,326,913 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,940,058 - 203,964,771 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,822,001 - 201,846,740 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,638,975 - 196,663,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02211,450,426 - 211,479,885 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,450,484 - 211,479,884 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,923,372 - 230,952,836 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,245,357 - 204,278,530 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12204,208,110 - 204,241,283 (+)NCBI
Celera2188,943,040 - 188,970,221 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Ratautistic disorder  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Clcc1Ratautosomal recessive nonsyndromic deafness  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal recessive nonsyndromic deafnessClinVar 
Clcc1RatChudley-Mccullough syndrome  ISOCLCC1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24033266 more ...
Clcc1Ratfundus dystrophy  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: Retinal dystrophyClinVarPMID:16189710 more ...
Clcc1Ratgenetic disease  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Clcc1RatHearing Loss  ISOCLCC1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24033266 and PMID:30311386
Clcc1Rathereditary spastic paraplegia 63  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 63ClinVarPMID:23911318 and PMID:28492532
Clcc1Ratretinitis pigmentosa 32  ISOCLCC1 (Homo sapiens)8554872ClinVar Annotator: match by term: Retinitis pigmentosa 32ClinVarPMID:16189710 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Ratretinitis pigmentosa 32  ISOCLCC1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Ratretinitis pigmentosa 32  ISOCLCC1 (Homo sapiens)7240710 OMIM 

1 to 20 of 60 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Rat(S)-nicotine increases expressionISOCLCC1 (Homo sapiens)6480464Nicotine results in increased expression of CLCC1 mRNACTDPMID:16949557
Clcc1Rat17beta-estradiol increases expressionISOClcc1 (Mus musculus)6480464Estradiol results in increased expression of CLCC1 mRNACTDPMID:39298647
Clcc1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOClcc1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CLCC1 mRNACTDPMID:21570461
Clcc1Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of CLCC1 mRNACTDPMID:21346803
Clcc1Rat2-methylcholine affects expressionISOCLCC1 (Homo sapiens)6480464beta-methylcholine affects the expression of CLCC1 mRNACTDPMID:21179406
Clcc1Rat3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CLCC1 mRNACTDPMID:30071829
Clcc1Rat4,4'-diaminodiphenylmethane increases expressionISOClcc1 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of CLCC1 mRNACTDPMID:18648102
Clcc1Rat4,4'-sulfonyldiphenol decreases expressionISOClcc1 (Mus musculus)6480464bisphenol S results in decreased expression of CLCC1 mRNACTDPMID:39298647
Clcc1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of CLCC1 mRNACTDPMID:24780913
Clcc1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of CLCC1 mRNACTDPMID:16483693
Clcc1Rataristolochic acid A decreases expressionISOCLCC1 (Homo sapiens)6480464aristolochic acid I results in decreased expression of CLCC1 mRNA and aristolochic acid I results in decreased expression of CLCC1 proteinCTDPMID:33212167
Clcc1Ratarsenous acid decreases expressionISOCLCC1 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of CLCC1 mRNACTDPMID:21461292
Clcc1Ratbenzo[a]pyrene increases methylationISOCLCC1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of CLCC1 5' UTRCTDPMID:27901495
Clcc1Ratbenzo[a]pyrene affects methylationISOCLCC1 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of CLCC1 promoterCTDPMID:27901495
Clcc1Ratbenzo[a]pyrene diol epoxide I decreases expressionISOCLCC1 (Homo sapiens)64804647 more ...CTDPMID:20018196
Clcc1Ratbenzo[a]pyrene diol epoxide I increases expressionISOCLCC1 (Homo sapiens)64804647 more ...CTDPMID:26238291
Clcc1Ratbilirubin IXalpha decreases expressionISOCLCC1 (Homo sapiens)6480464Bilirubin results in decreased expression of CLCC1 mRNACTDPMID:20196124
Clcc1Ratbis(2-chloroethyl) sulfide decreases expressionISOCLCC1 (Homo sapiens)6480464Mustard Gas results in decreased expression of CLCC1 mRNACTDPMID:25102026
Clcc1Ratbis(2-ethylhexyl) phthalate increases expressionISOClcc1 (Mus musculus)6480464Diethylhexyl Phthalate results in increased expression of CLCC1 mRNACTDPMID:34319233
Clcc1Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of CLCC1 mRNACTDPMID:25181051

1 to 20 of 60 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Ratchloride transmembrane transport involved_inIEAGO:00052541600115GO_REF:0000108GOCGO_REF:0000108
Clcc1Ratchloride transport involved_inIDA 1299391PMID:11279057HGNC-UCL 
Clcc1Ratchloride transport involved_inIEAUniProtKB-KW:KW-08691600115GO_REF:0000043UniProtGO_REF:0000043
Clcc1Ratendoplasmic reticulum calcium ion homeostasis involved_inISOCLCC1 (Homo sapiens)1624291 PMID:37142673RGDPMID:37142673
Clcc1Ratendoplasmic reticulum calcium ion homeostasis involved_inISOClcc1 (Mus musculus)1624291 PMID:37142673RGDPMID:37142673
Clcc1Ratendoplasmic reticulum calcium ion homeostasis involved_inIEAUniProtKB:Q96S66 and ensembl:ENSP000003589861600115GO_REF:0000107EnsemblGO_REF:0000107
Clcc1Ratmonoatomic ion transmembrane transport involved_inIEAUniProtKB-KW:KW-04071600115GO_REF:0000043UniProtGO_REF:0000043
Clcc1Ratmonoatomic ion transport involved_inIEAUniProtKB-KW:KW-04061600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Clcc1Ratchloride channel complex part_ofIEAUniProtKB-KW:KW-08691600115GO_REF:0000043UniProtGO_REF:0000043
Clcc1Ratcytoplasm located_inIDA 1299391PMID:11279057HGNC-UCL 
Clcc1Ratendoplasmic reticulum located_inISOCLCC1 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Clcc1Ratendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Clcc1Ratendoplasmic reticulum is_active_inIBAMGI:2385186 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Clcc1Ratendoplasmic reticulum located_inIMP 1299391PMID:11279057HGNC-UCL 
Clcc1Ratendoplasmic reticulum located_inIEAUniProtKB:Q96S66 and ensembl:ENSP000003589861600115GO_REF:0000107EnsemblGO_REF:0000107
Clcc1Ratendoplasmic reticulum membrane located_inISOCLCC1 (Homo sapiens)1624291 PMID:37142673RGDPMID:37142673
Clcc1Ratendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-00971600115GO_REF:0000044UniProtGO_REF:0000044
Clcc1Ratendoplasmic reticulum membrane located_inISOClcc1 (Mus musculus)1624291 PMID:37142673RGDPMID:37142673
Clcc1Ratendoplasmic reticulum membrane located_inIEAUniProtKB:Q96S66 and ensembl:ENSP000003589861600115GO_REF:0000107EnsemblGO_REF:0000107
Clcc1RatGolgi apparatus located_inIMP 1299391PMID:11279057HGNC-UCL 
Clcc1Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Clcc1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Clcc1Ratmembrane is_active_inIBAMGI:2385186 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Clcc1Ratmitochondria-associated endoplasmic reticulum membrane contact site located_inIEAUniProtKB:Q96S66 and ensembl:ENSP000003589861600115GO_REF:0000107EnsemblGO_REF:0000107
Clcc1Ratmitochondria-associated endoplasmic reticulum membrane contact site located_inISOCLCC1 (Homo sapiens)1624291 PMID:31653868RGDPMID:31653868
Clcc1Ratmitochondria-associated endoplasmic reticulum membrane contact site located_inISSUniProtKB:Q96S661600115GO_REF:0000024UniProtGO_REF:0000024
Clcc1Ratmitochondrion NOT|located_inNAS 1299391PMID:11279057HGNC-UCL 
Clcc1Ratnucleus located_inIDA 1299391PMID:11279057HGNC-UCL 
1 to 20 of 20 rows

Molecular Function
1 to 9 of 9 rows

  
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus. Nagasawa M, etal., J Biol Chem 2001 Jun 8;276(23):20413-8. Epub 2001 Mar 5.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:19946888   PMID:31653868  



Clcc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,984,455 - 199,015,015 (+)NCBIGRCr8
mRatBN7.22196,296,350 - 196,326,914 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2196,296,393 - 196,326,913 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,940,058 - 203,964,771 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,822,001 - 201,846,740 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,638,975 - 196,663,716 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02211,450,426 - 211,479,885 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,450,484 - 211,479,884 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,923,372 - 230,952,836 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,245,357 - 204,278,530 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12204,208,110 - 204,241,283 (+)NCBI
Celera2188,943,040 - 188,970,221 (+)NCBICelera
Cytogenetic Map2q34NCBI
CLCC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381108,929,505 - 108,963,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1108,881,885 - 108,963,527 (-)EnsemblGRCh38hg38GRCh38
GRCh371109,472,127 - 109,506,106 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361109,273,653 - 109,307,634 (-)NCBINCBI36Build 36hg18NCBI36
Celera1107,741,688 - 107,775,523 (-)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1107,364,991 - 107,398,998 (-)NCBIHuRef
CHM1_11109,587,075 - 109,621,067 (-)NCBICHM1_1
T2T-CHM13v2.01108,962,861 - 108,996,846 (-)NCBIT2T-CHM13v2.0
Clcc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,561,194 - 108,586,156 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,561,229 - 108,586,156 (+)EnsemblGRCm39 Ensembl
GRCm383108,653,878 - 108,678,840 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,653,913 - 108,678,840 (+)EnsemblGRCm38mm10GRCm38
MGSCv373108,456,831 - 108,481,758 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,782,303 - 108,806,068 (+)NCBIMGSCv36mm8
Celera3110,988,607 - 111,013,587 (+)NCBICelera
Cytogenetic Map3F3NCBI
cM Map347.49NCBI
Clcc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543512,387,575 - 12,408,801 (-)NCBIChiLan1.0ChiLan1.0
CLCC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,340,064 - 118,371,568 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11117,500,106 - 117,531,651 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,309,680 - 111,340,851 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,474,158 - 110,505,626 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,473,752 - 110,505,613 (-)Ensemblpanpan1.1panPan2
CLCC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,807,432 - 42,829,317 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl642,807,064 - 42,829,273 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha645,582,407 - 45,604,915 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0643,139,838 - 43,162,167 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl643,139,894 - 43,162,212 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1642,870,406 - 42,892,709 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0642,828,824 - 42,851,132 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0643,270,389 - 43,292,703 (+)NCBIUU_Cfam_GSD_1.0
Clcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,574,603 - 19,596,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936704517,707 - 539,585 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936704518,040 - 539,526 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLCC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4111,080,682 - 111,101,303 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14111,080,648 - 111,101,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,572,770 - 121,592,914 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLCC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12024,627,309 - 24,657,684 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2024,610,854 - 24,655,653 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603833,694,780 - 33,732,055 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clcc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247724,705,198 - 4,744,252 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247724,705,198 - 4,744,052 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Clcc1
169 total Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
2 230950880 230950881 C T snv DOB/Oda (KyushuU) View more Information

Predicted Target Of
Summary Value
Count of predictions:1011
Count of miRNA genes:310
Interacting mature miRNAs:402
Transcripts:ENSRNOT00000027617, ENSRNOT00000051701, ENSRNOT00000055859
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 65 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat

1 to 10 of 65 rows
RH131755  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22196,326,624 - 196,326,804 (+)MAPPERmRatBN7.2
Rnor_6.02211,479,596 - 211,479,775NCBIRnor6.0
Rnor_5.02230,952,547 - 230,952,726UniSTSRnor5.0
RGSC_v3.42204,278,241 - 204,278,420UniSTSRGSC3.4
Celera2188,969,932 - 188,970,111UniSTS
RH 3.4 Map21398.5UniSTS
Cytogenetic Map2q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000027617   ⟹   ENSRNOP00000027617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2196,306,297 - 196,325,036 (+)Ensembl
Rnor_6.0 Ensembl2211,460,373 - 211,478,007 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000051701   ⟹   ENSRNOP00000042185
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2196,296,393 - 196,326,913 (+)Ensembl
Rnor_6.0 Ensembl2211,450,484 - 211,479,884 (+)Ensembl
RefSeq Acc Id: NM_133414   ⟹   NP_596905
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,984,511 - 199,015,015 (+)NCBI
mRatBN7.22196,296,406 - 196,326,914 (+)NCBI
Rnor_6.02211,450,484 - 211,479,885 (+)NCBI
Rnor_5.02230,923,372 - 230,952,836 (+)NCBI
RGSC_v3.42204,245,357 - 204,278,530 (+)RGD
Celera2188,943,040 - 188,970,221 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233128   ⟹   XP_006233190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,984,489 - 199,015,015 (+)NCBI
mRatBN7.22196,296,367 - 196,326,914 (+)NCBI
Rnor_6.02211,450,452 - 211,479,885 (+)NCBI
Rnor_5.02230,923,372 - 230,952,836 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017590597   ⟹   XP_017446086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,984,489 - 199,015,015 (+)NCBI
mRatBN7.22196,296,366 - 196,326,914 (+)NCBI
Rnor_6.02211,450,451 - 211,479,885 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063281217   ⟹   XP_063137287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82198,984,455 - 199,015,015 (+)NCBI
RefSeq Acc Id: NP_596905   ⟸   NM_133414
- Peptide Label: precursor
- UniProtKB: Q9WU61 (UniProtKB/Swiss-Prot),   Q8VIF1 (UniProtKB/Swiss-Prot),   Q8VIF0 (UniProtKB/Swiss-Prot),   Q8VIE9 (UniProtKB/Swiss-Prot),   Q8VIE8 (UniProtKB/Swiss-Prot),   Q66HQ5 (UniProtKB/Swiss-Prot),   A0A140TAF5 (UniProtKB/TrEMBL),   A6HV18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233190   ⟸   XM_006233128
- Peptide Label: isoform X1
- UniProtKB: Q8VIF1 (UniProtKB/Swiss-Prot),   Q8VIF0 (UniProtKB/Swiss-Prot),   Q8VIE9 (UniProtKB/Swiss-Prot),   Q8VIE8 (UniProtKB/Swiss-Prot),   Q66HQ5 (UniProtKB/Swiss-Prot),   Q9WU61 (UniProtKB/Swiss-Prot),   A0A140TAF5 (UniProtKB/TrEMBL),   A6HV18 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446086   ⟸   XM_017590597
- Peptide Label: isoform X2
- UniProtKB: A6HV21 (UniProtKB/TrEMBL),   A6HV24 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000042185   ⟸   ENSRNOT00000051701
Ensembl Acc Id: ENSRNOP00000027617   ⟸   ENSRNOT00000027617

Name Modeler Protein Id AA Range Protein Structure
AF-Q9WU61-F1-model_v2 AlphaFold Q9WU61 1-541 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691687
Promoter ID:EPDNEW_R2212
Type:initiation region
Name:Clcc1_1
Description:chloride channel CLIC-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02211,450,475 - 211,450,535EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-51595 BioCyc
Ensembl Genes ENSRNOG00000020360 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027617 ENTREZGENE
  ENSRNOT00000051701 ENTREZGENE
  ENSRNOT00000134976 ENTREZGENE
IMAGE_CLONE IMAGE:7128078 IMAGE-MGC_LOAD
InterPro Chloride_chnl_CLIC-like UniProtKB/Swiss-Prot
KEGG Report rno:170927 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93226 IMAGE-MGC_LOAD
NCBI Gene 170927 ENTREZGENE
PANTHER CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR34093 UniProtKB/Swiss-Prot
Pfam MCLC UniProtKB/Swiss-Prot
PhenoGen Clcc1 PhenoGen
RatGTEx ENSRNOG00000020360 RatGTEx
UniProt A0A140TAF5 ENTREZGENE, UniProtKB/TrEMBL
  A6HV18 ENTREZGENE, UniProtKB/TrEMBL
  A6HV20_RAT UniProtKB/TrEMBL
  A6HV21 ENTREZGENE, UniProtKB/TrEMBL
  A6HV23_RAT UniProtKB/TrEMBL
  A6HV24 ENTREZGENE, UniProtKB/TrEMBL
  A6HV26_RAT UniProtKB/TrEMBL
  CLCC1_RAT UniProtKB/Swiss-Prot
  D3ZKI2_RAT UniProtKB/TrEMBL
  Q66HQ5 ENTREZGENE
  Q8VIE8 ENTREZGENE
  Q8VIE9 ENTREZGENE
  Q8VIF0 ENTREZGENE
  Q8VIF1 ENTREZGENE
  Q9WU61 ENTREZGENE
UniProt Secondary Q66HQ5 UniProtKB/Swiss-Prot
  Q8VIE8 UniProtKB/Swiss-Prot
  Q8VIE9 UniProtKB/Swiss-Prot
  Q8VIF0 UniProtKB/Swiss-Prot
  Q8VIF1 UniProtKB/Swiss-Prot
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Clcc1  chloride channel CLIC-like 1  Mclc  Mid-1-related chloride channel 1  Symbol and Name updated 1299863 APPROVED
2005-07-08 Mclc  Mid-1-related chloride channel 1  LOC170927    Symbol updated 1299863 APPROVED