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Gene: Kcnk13 (potassium two pore domain channel subfamily K member 13) Rattus norvegicus

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Symbol:

Kcnk13

Name:

potassium two pore domain channel subfamily K member 13

RGD ID:

68941

Description:

Enables potassium channel activity. Predicted to be involved in several processes, including regulation of NLRP3 inflammasome complex assembly; regulation of excitatory synapse pruning; and regulation of resting membrane potential. Located in plasma membrane. Orthologous to human KCNK13 (potassium two pore domain channel subfamily K member 13); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

potassium channel subfamily K member 13; potassium channel, subfamily K, member 13; potassium channel, two pore domain subfamily K, member 13; prdx1; tandem pore domain halothane-inhibited potassium channel 1; tandem pore domain potassium channel THIK-1; THIK-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	124,970,363 - 125,074,919 (+)	NCBI		GRCr8
mRatBN7.2	6	119,240,825 - 119,345,292 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	119,242,188 - 119,345,240 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	119,399,630 - 119,508,885 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	119,696,436 - 119,805,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	119,031,301 - 119,140,558 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	123,971,030 - 124,077,249 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	123,974,798 - 124,077,197 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	133,199,698 - 133,305,279 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	124,174,021 - 124,190,997 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	124,177,767 - 124,178,198 (+)	NCBI
Celera	6	116,771,899 - 116,775,334 (+)	NCBI		Celera
Celera	6	116,775,647 - 116,878,414 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	COVID-19		ISO	KCNK13 (Homo sapiens)	9068941	mRNA:increased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	achondrogenesis type IA		ISO	KCNK13 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Achondrogenesis and type IA	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of KCNK13 mRNA	CTD	PMID:22206623
Kcnk13	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of KCNK13 mRNA	CTD	PMID:32109520 and PMID:33387578
Kcnk13	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases methylation	EXP		6480464	Tetrachlorodibenzodioxin results in increased methylation of KCNK13 gene	CTD	PMID:26431795
Kcnk13	Rat	2,3,7,8-Tetrachlorodibenzofuran	decreases expression	EXP		6480464	2 more ...	CTD	PMID:32109520
Kcnk13	Rat	3,3',5,5'-tetrabromobisphenol A	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	tetrabromobisphenol A results in decreased expression of KCNK13 mRNA	CTD	PMID:25172293
Kcnk13	Rat	3,4-methylenedioxymethamphetamine	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of KCNK13 mRNA	CTD	PMID:20188158
Kcnk13	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	bisphenol S results in increased expression of KCNK13 mRNA	CTD	PMID:30951980
Kcnk13	Rat	4,4'-sulfonyldiphenol	affects methylation	ISO	Kcnk13 (Mus musculus)	6480464	bisphenol S affects the methylation of KCNK13 gene	CTD	PMID:31683443
Kcnk13	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	bisphenol S results in decreased expression of KCNK13 mRNA	CTD	PMID:39298647
Kcnk13	Rat	4-hydroxyphenyl retinamide	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	Fenretinide results in decreased expression of KCNK13 mRNA	CTD	PMID:28973697
Kcnk13	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of KCNK13 mRNA	CTD	PMID:24780913
Kcnk13	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of KCNK13 mRNA	CTD	PMID:31881176
Kcnk13	Rat	amitrole	increases expression	EXP		6480464	Amitrole results in increased expression of KCNK13 mRNA	CTD	PMID:30047161
Kcnk13	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of KCNK13 mRNA	CTD	PMID:16483693
Kcnk13	Rat	amphetamine	increases expression	EXP		6480464	Amphetamine results in increased expression of KCNK13 mRNA	CTD	PMID:30779732
Kcnk13	Rat	benzo[a]pyrene	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of KCNK13 mRNA	CTD	PMID:20064835
Kcnk13	Rat	benzo[a]pyrene	affects methylation	ISO	KCNK13 (Homo sapiens)	6480464	Benzo(a)pyrene affects the methylation of KCNK13 promoter	CTD	PMID:27901495
Kcnk13	Rat	benzo[a]pyrene	decreases methylation	ISO	KCNK13 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of KCNK13 exon	CTD	PMID:27901495
Kcnk13	Rat	benzo[a]pyrene	increases methylation	ISO	KCNK13 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of KCNK13 5' UTR	CTD	PMID:27901495
Kcnk13	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of KCNK13 mRNA	CTD	PMID:25181051
Kcnk13	Rat	bisphenol A	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	bisphenol A results in increased expression of KCNK13 mRNA	CTD	PMID:32156529
Kcnk13	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of KCNK13 mRNA	CTD	PMID:34973380
Kcnk13	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of KCNK13 gene	CTD	PMID:28505145
Kcnk13	Rat	bisphenol F	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	bisphenol F results in increased expression of KCNK13 mRNA	CTD	PMID:30951980
Kcnk13	Rat	carbon nanotube	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	Nanotubes more ...	CTD	PMID:25554681
Kcnk13	Rat	choline	multiple interactions	ISO	Kcnk13 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of KCNK13 more ...	CTD	PMID:20938992
Kcnk13	Rat	cyclosporin A	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Cyclosporine results in decreased expression of KCNK13 mRNA	CTD	PMID:25596134
Kcnk13	Rat	dioxygen	multiple interactions	ISO	Kcnk13 (Mus musculus)	6480464	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of KCNK13 mRNA	CTD	PMID:30529165
Kcnk13	Rat	diuron	increases expression	EXP		6480464	Diuron results in increased expression of KCNK13 mRNA	CTD	PMID:21551480
Kcnk13	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of KCNK13 mRNA	CTD	PMID:29391264
Kcnk13	Rat	fenofibrate	increases expression	ISO	KCNK13 (Homo sapiens)	6480464	Fenofibrate results in increased expression of KCNK13 mRNA	CTD	PMID:25572481 and PMID:25596134
Kcnk13	Rat	flavonoids	increases expression	EXP		6480464	Flavonoids results in increased expression of KCNK13 mRNA	CTD	PMID:18035473
Kcnk13	Rat	folic acid	multiple interactions	ISO	Kcnk13 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of KCNK13 more ...	CTD	PMID:20938992
Kcnk13	Rat	folic acid	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	Folic Acid results in decreased expression of KCNK13 mRNA	CTD	PMID:25629700
Kcnk13	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of KCNK13 mRNA	CTD	PMID:33387578
Kcnk13	Rat	L-methionine	multiple interactions	ISO	Kcnk13 (Mus musculus)	6480464	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of KCNK13 more ...	CTD	PMID:20938992
Kcnk13	Rat	lipopolysaccharide	multiple interactions	ISO	KCNK13 (Homo sapiens)	6480464	[S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of KCNK13 mRNA	CTD	PMID:35811015
Kcnk13	Rat	methimazole	increases expression	EXP		6480464	Methimazole results in increased expression of KCNK13 mRNA	CTD	PMID:30047161
Kcnk13	Rat	niclosamide	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Niclosamide results in decreased expression of KCNK13 mRNA	CTD	PMID:36318118
Kcnk13	Rat	O-methyleugenol	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	methyleugenol results in decreased expression of KCNK13 mRNA	CTD	PMID:32234424
Kcnk13	Rat	paracetamol	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Acetaminophen results in decreased expression of KCNK13 mRNA	CTD	PMID:26690555
Kcnk13	Rat	paracetamol	increases expression	ISO	KCNK13 (Homo sapiens)	6480464	Acetaminophen results in increased expression of KCNK13 mRNA	CTD	PMID:29067470
Kcnk13	Rat	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	ISO	KCNK13 (Homo sapiens)	6480464	[S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of KCNK13 mRNA	CTD	PMID:35811015
Kcnk13	Rat	sunitinib	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Sunitinib results in decreased expression of KCNK13 mRNA	CTD	PMID:31533062
Kcnk13	Rat	testosterone	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	Testosterone deficiency results in increased expression of KCNK13 mRNA	CTD	PMID:33848595
Kcnk13	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of KCNK13 mRNA	CTD	PMID:34492290
Kcnk13	Rat	titanium dioxide	decreases expression	ISO	Kcnk13 (Mus musculus)	6480464	titanium dioxide results in decreased expression of KCNK13 mRNA	CTD	PMID:29264374
Kcnk13	Rat	titanium dioxide	decreases methylation	ISO	Kcnk13 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of KCNK13 gene	CTD	PMID:35295148
Kcnk13	Rat	trichloroethene	increases expression	EXP		6480464	Trichloroethylene results in increased expression of KCNK13 mRNA	CTD	PMID:33387578
Kcnk13	Rat	triclosan	decreases expression	ISO	KCNK13 (Homo sapiens)	6480464	Triclosan results in decreased expression of KCNK13 mRNA	CTD	PMID:30510588
Kcnk13	Rat	triptonide	increases expression	ISO	Kcnk13 (Mus musculus)	6480464	triptonide results in increased expression of KCNK13 mRNA	CTD	PMID:33045310
Kcnk13	Rat	urethane	increases expression	ISO	KCNK13 (Homo sapiens)	6480464	Urethane results in increased expression of KCNK13 mRNA	CTD	PMID:28818685

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	monoatomic ion transmembrane transport	involved_in	IEA	UniProtKB-KW:KW-0407 and UniProtKB-KW:KW-0851	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	monoatomic ion transport	involved_in	IEA	UniProtKB-KW:KW-0406	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	potassium ion transmembrane transport	involved_in	IEA	UniProtKB-KW:KW-0631	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	potassium ion transmembrane transport	involved_in	IEA	InterPro:IPR003280 and InterPro:IPR005410	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kcnk13	Rat	potassium ion transmembrane transport	involved_in	IBA	FB:FBgn0017561 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kcnk13	Rat	potassium ion transport	involved_in	IEA	UniProtKB-KW:KW-0633	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	regulation of excitatory synapse pruning	involved_in	ISO	Kcnk13 (Mus musculus)	1624291	PMID:34642249	RGD	PMID:34642249
Kcnk13	Rat	regulation of excitatory synapse pruning	involved_in	IEA	UniProtKB:Q8R1P5 and ensembl:ENSMUSP00000051846	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	regulation of excitatory synapse pruning	involved_in	ISS	UniProtKB:Q8R1P5	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kcnk13	Rat	regulation of NLRP3 inflammasome complex assembly	involved_in	ISO	Kcnk13 (Mus musculus)	1624291	PMID:35353387	RGD	PMID:35353387
Kcnk13	Rat	regulation of NLRP3 inflammasome complex assembly	involved_in	IEA	UniProtKB:Q8R1P5 and ensembl:ENSMUSP00000051846	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	regulation of NLRP3 inflammasome complex assembly	involved_in	ISS	UniProtKB:Q8R1P5	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kcnk13	Rat	regulation of resting membrane potential	involved_in	ISO	Kcnk13 (Mus musculus)	1624291	PMID:29290552	RGD	PMID:29290552
Kcnk13	Rat	regulation of resting membrane potential	involved_in	IEA	UniProtKB:Q8R1P5 and ensembl:ENSMUSP00000051846	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	regulation of resting membrane potential	involved_in	ISS	UniProtKB:Q8R1P5	1600115	GO_REF:0000024	UniProt	GO_REF:0000024

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	membrane	located_in	IEA	InterPro:IPR003280 and InterPro:IPR005410	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kcnk13	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	monoatomic ion channel complex	part_of	IEA	UniProtKB-KW:KW-0851	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	plasma membrane	located_in	IDA		67928	PMID:11060316	UniProt
Kcnk13	Rat	plasma membrane	located_in	IEA	UniProtKB:Q9HB14 and ensembl:ENSP00000282146	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	plasma membrane	is_active_in	IBA	MGI:109322 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kcnk13	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Kcnk13	Rat	plasma membrane	located_in	ISO	KCNK13 (Homo sapiens)	1624291	PMID:24163367 and PMID:25148687	RGD	PMID:24163367 and PMID:25148687

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Kcnk13	Rat	identical protein binding	enables	IEA	UniProtKB:Q9HB14 and ensembl:ENSP00000282146	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	identical protein binding	enables	ISS	UniProtKB:Q9HB14	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kcnk13	Rat	identical protein binding	enables	ISO	KCNK13 (Homo sapiens)	1624291	PMID:25148687	RGD	PMID:25148687
Kcnk13	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	outward rectifier potassium channel activity	enables	IBA	MGI:109366 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kcnk13	Rat	potassium channel activity	enables	IDA		67928	PMID:11060316	UniProt
Kcnk13	Rat	potassium channel activity	enables	IEA	InterPro:IPR003280 and InterPro:IPR005410	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Kcnk13	Rat	potassium channel activity	enables	ISO	KCNK13 (Homo sapiens)	1624291	PMID:24163367 and PMID:25148687	RGD	PMID:24163367 and PMID:25148687
Kcnk13	Rat	potassium channel activity	enables	IEA	UniProtKB:Q9HB14 and ensembl:ENSP00000282146	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Kcnk13	Rat	potassium channel activity	enables	IEA	UniProtKB-KW:KW-0631	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Kcnk13	Rat	potassium ion leak channel activity	enables	IBA	FB:FBgn0017561 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Kcnk13	Rat	protein binding	enables	ISO	KCNK13 (Homo sapiens)	1624291	UniProtKB:Q9HB15 and PMID:25148687	RGD	PMID:25148687
Kcnk13	Rat	protein heterodimerization activity	enables	ISS	UniProtKB:Q9HB14	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Kcnk13	Rat	protein heterodimerization activity	enables	ISO	KCNK13 (Homo sapiens)	1624291	PMID:25148687	RGD	PMID:25148687
Kcnk13	Rat	protein heterodimerization activity	enables	IEA	UniProtKB:Q9HB14 and ensembl:ENSP00000282146	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
3.	Thik-1 and thik-2, a novel subfamily of tandem pore domain k+ channels.	Rajan S, etal., J Biol Chem 2001 Mar 9;276(10):7302-11.
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:12960165	PMID:18209473	PMID:28676376	PMID:29290552	PMID:33960499

Kcnk13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	124,970,363 - 125,074,919 (+)	NCBI		GRCr8
mRatBN7.2	6	119,240,825 - 119,345,292 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	119,242,188 - 119,345,240 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	119,399,630 - 119,508,885 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	119,696,436 - 119,805,697 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	119,031,301 - 119,140,558 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	123,971,030 - 124,077,249 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	123,974,798 - 124,077,197 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	133,199,698 - 133,305,279 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	124,174,021 - 124,190,997 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	124,177,767 - 124,178,198 (+)	NCBI
Celera	6	116,771,899 - 116,775,334 (+)	NCBI		Celera
Celera	6	116,775,647 - 116,878,414 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

KCNK13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	90,061,994 - 90,185,853 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	90,061,994 - 90,185,853 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	90,528,338 - 90,652,197 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	89,597,861 - 89,721,948 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	89,597,860 - 89,721,948	NCBI
Celera	14	70,575,304 - 70,699,365 (+)	NCBI		Celera
Cytogenetic Map	14	q32.11	NCBI
HuRef	14	70,702,077 - 70,826,787 (+)	NCBI		HuRef
CHM1_1	14	90,465,908 - 90,590,258 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	84,286,196 - 84,410,029 (+)	NCBI		T2T-CHM13v2.0

Kcnk13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	99,928,132 - 100,028,941 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	99,930,758 - 100,028,941 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	99,963,149 - 100,062,682 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	99,964,499 - 100,062,682 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	101,202,709 - 101,300,892 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	100,366,958 - 100,463,726 (+)	NCBI		MGSCv36	mm8
Celera	12	101,190,780 - 101,289,302 (+)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	50.43	NCBI

Kcnk13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	12,522,737 - 12,663,480 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	12,522,063 - 12,660,078 (+)	NCBI	ChiLan1.0	ChiLan1.0

KCNK13
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	91,204,974 - 91,333,492 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	90,421,486 - 90,549,998 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	70,678,256 - 70,803,575 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	90,031,782 - 90,155,541 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	90,032,219 - 90,154,687 (+)	Ensembl	panpan1.1		panPan2

KCNK13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	61,127,385 - 61,223,113 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	61,126,883 - 61,222,650 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	60,706,583 - 60,802,697 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	61,399,216 - 61,495,259 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	61,399,231 - 61,494,798 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	61,080,667 - 61,176,758 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	61,129,204 - 61,225,384 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	61,457,778 - 61,553,937 (+)	NCBI		UU_Cfam_GSD_1.0

Kcnk13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	14,657,041 - 14,747,908 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936488	17,322,431 - 17,411,923 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936488	17,410,165 - 17,411,040 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KCNK13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	111,867,546 - 111,980,663 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	111,866,471 - 111,981,304 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	118,431,107 - 118,546,546 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KCNK13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	67,782,523 - 67,912,950 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	67,781,977 - 67,913,195 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	55,079,953 - 55,205,458 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Kcnk13
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	12,207,094 - 12,317,720 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	12,206,237 - 12,319,321 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Kcnk13
832 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	90
Count of miRNA genes:	78
Interacting mature miRNAs:	87
Transcripts:	ENSRNOT00000075794
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1300076	Glom8	Glomerulus QTL 8	7	9e-09	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat

BE121246

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	119,345,095 - 119,345,245 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	124,077,053 - 124,077,202	NCBI	Rnor6.0
Rnor_5.0	6	133,305,083 - 133,305,232	UniSTS	Rnor5.0
Celera	6	116,878,270 - 116,878,419	UniSTS
RH 3.4 Map	6	859.9	UniSTS
Cytogenetic Map	6	q32	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	45	113	91	90	59	25	59	6	214	93	93	45	60	31


RefSeq Transcripts	NM_022293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240447	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008776304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC123183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF287301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ457059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000075794 ⟹ ENSRNOP00000067310

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	119,242,188 - 119,345,240 (+)	Ensembl
Rnor_6.0 Ensembl	6	123,974,798 - 124,077,197 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101370 ⟹ ENSRNOP00000077400

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	119,242,193 - 119,247,557 (+)	Ensembl

RefSeq Acc Id:

NM_022293 ⟹ NP_071629

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	124,971,809 - 125,074,873 (+)	NCBI
mRatBN7.2	6	119,242,188 - 119,345,240 (+)	NCBI
Rnor_6.0	6	123,974,798 - 124,077,197 (+)	NCBI
Rnor_5.0	6	133,199,698 - 133,305,279 (+)	NCBI
RGSC_v3.4	6	124,174,021 - 124,190,997 (+)	RGD
Celera	6	116,775,647 - 116,878,414 (+)	RGD

Sequence:

show sequence

AGGCAGAGCGGGCTAAGATCCGCAGAGCCGGATCTTACCAGGGGCGTGGGCACAAGTCCGCGGGCAGCGACCCTCGCGGGGTTGTCCTCCAGTGCCATGGCTGGCCGCGGTTGCAGCTGCAGCCCCGG
CCACCTGAACGAGGACAACGCGCGCTTCCTGCTGCTCGCGGGGCTCATCCTGCTTTACCTGCTGGGCGGCGCCGCAGTCTTCTCCGCGCTGGAGCTAGCGCAGGAGCTGCAGGCCAAGCAGCGCTGGG
AAGAGCGCCTGGCCAACTTCAGCAGGGGCCACAACCTGAGCCGCGAAGAGCTGCGAGGCTTCCTCCGCCACTACGAGGAAGCCACCAAGGCGGGCATCCGCATGGACAGCGTGCGCCCTCGCTGGGAC
TTCACGGGCGCCTTCTACTTCGTGGGCACAGTGGTAACTACCATAGGGTTCGGGATGACGACCCCAGCCACAACGGGAGGGAAGGTTTTTCTGATCTTTTATGGTCTCATTGGATGTGCGAGTACCAT
CCTCTTCTTCAACCTCTTTCTGGAGCGGCTGATCACCGTCATCGCCTACGTCATGAGAACCTGCCACCACCAGCAGCTGCGCAGACGTGGGACGGTAGCCCGGGACAACAGGAAGGCCCCTAGAAAGG
GCGAGGCAGACAGCCTGGCTGGCTGGAAGCCCTCCGTGTACTACGTCATGCTGATCCTGTGCTTGGCATCAGTAGCCATCTCCTGTGGAGCCTCGGCTCTGTACACCACCATGGAAGGCTGGAGCTAC
TTTGACTCCGTCTACTTCTGTTTTGTGGCTTCAAGCACCATTGGCTTCGGGGACCTGGTGAGCAGCCAGAACGCTCAGTATGAGAACGAAGGGCTCTACCGCTTTGTCAATTTCTTCTTCATCCTCAT
GGGTGTCTGCTGCATCTACTCCATGTTTAACGTCATCTCCATCCTGATCAAACAGACAGTGAACTGGATCCTGAGGAAACTGGATAGCGGGTGCTTCCCACAATGCCAAAGAGGACTCCTGCGGTCCA
GGAGGAACGTGGTGATGCCGGGCAACATCCGGAACAGGTGCAACATCTCCATAGAGACGGACGGGGTGATGGAAAGTGACACTGATGGGCGACGTCTCTCGGGGGAGATGATCTCCATGAAGGACACC
AACAAGGTCTCCCTGGCCATCCTGCAGAAGCAGTTGTCCGAGATGGCCAATGGTGGACCCCACCAGACCAGCACATCCTCCCGGGATGATGAGTTCTCAGGGGGCGTGGGAGCCTTTGCAGTAATGAA
TAACAGGTTGGCAGAGACCAGTGGGGACAGGTAGGGACCAGAAGTAGCTGCCACATGAAGAAACCCAGGGCAAGTGGGGGATAGGTCACTGCCACACCCCCAGGGACCTCAGCTGTGTCTCTGGCTGT
TGGAATTAGCATCTCCAGTCCAGCTTTTGAAATCTGACCTTGGCCCTGGGCAGCAGTAAACCTCTCAAGGTTGGGACTGGAGCCATCTTCCCTGACTCTTACTTTACCCTTGAATTCCCAATTTCGCG
TTTGGAATTGTCTGGGGGAGATGGGTTTCCGTCCAGCTTTGATCCCCTACCCCAACCCGGTCATGATCCATCCCTAGGGAGGGAAAGCCCCGAAAAGCCTGACTCTGTCATGTAGTGTGAATGGCGGC
TGAACTTCACCCAGCCCCTCAAGAAAAGGCAGCGAACATTCCCGAATGCCTCTAGGCCTTGTTCTATTATTGGTTCCACTAATAGGGAAAACATCTAACTTTCTCTTTATATCTGCTTCTCTGTTTGG
GAGTCTTGGTTTCGTTTTGTTTTGTTTCCTATCTGACTAGTGTATCTTTTTGGATCTCAGATGATAAGGAAACCAAGTCTACCTTCAAACCTCTAAGTTGTAGCAAGATGAAGGCAGTGAGTCAAAGA
GGAGGAAAGCTCCCATCTTGTAACTAAAGCCTACCGCTTACTGTGTTCTTTCTGAATGGTTACACGGATTATGTCATTTTACCAGGGCCTGGAGCCTGCTGTAAAGGCAACC

hide sequence

RefSeq Acc Id:

XM_006240447 ⟹ XP_006240509

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	124,970,363 - 125,074,919 (+)	NCBI
mRatBN7.2	6	119,240,825 - 119,345,292 (+)	NCBI
Rnor_6.0	6	123,971,030 - 124,077,249 (+)	NCBI
Rnor_5.0	6	133,199,698 - 133,305,279 (+)	NCBI

Sequence:

show sequence

AAGTTCCAGGGCAGCTAGGACTTTACAAAGAAACCATCTTAGGGATGGCAAGAGCATCTAAGGGAGCCCCACAGCCCTCAGCGTCTGTAATAACAAGCGGATAGATTCCTTAGAGCTGAACAAAAGTA
ACCTGCTTCCAGCTCTCCTGTACCTTATTATTAGACACTGATCAGACAAGACTTTTTTTAAGTTAAAGTAAACCTCCACTTTAGGTGACATAGTTGCATGCATAGAAACTCCTAAGGGACCATTGAAA
CTAATGAAGGAATGCAGCCAGTTTGTGGGATACAAAGCAAACCTGAAAAGATGAAGCATTTGAATTTATGTGCTCAAATAAATCTTTATGTTGGATTCATAAAAGATGTGCATGACCTCTGTGCTATA
ACAAGGGAGAGCTACATATATGCAGAGATAGACTCATTCATGAATCATCGAAGTACCACTTCTTCCCAAAACATATTTAACACAGTCCTGGTCAAGATAACAGCCTTTTTCCGTGCCTGTGTTTAAAA
CGTCTGTCTTAAAAACCACAGCCCTTTGATTTTTAAAATGGAAACAATTTATTATACCCAAGGAAATACTGAAAAAGAAGAGCTAAGTTGGAGACTGCATTTCTTGACTCCAAGAGCTATAAAATGCA
TTTAAATGTGTTTTATGGCATAACAACTAGATAAATAGAAAATGGGCAAAATAAGAGAGTCCTGAAATAAATTATTCTTACTTTTCTGCTCGATAAATGCCATTAGGAAAAGTGAATATGCTTTTGGA
CAATATGGCCTCGTCTCACTTGCACAATAAATAAACTCAATGCCCAACATACAAAGTAGGGGAGAGAGACAAGAAACAAACACAACCTTGAAGGCAGCAATGATATAACACACAGAGGATAGCAAACA
TTACAGACTGGAAAATTGGACTTTACCAAAACTGAAAACTTTGTCAGAAAACTTTTTCTTAACAAGTGGGCATTCCAGAAACCAAAACAATAAGAGTTGCAAAATACACATCTAAGAAAGGACCAGTA
GCTAGATTATATGAAACACTGTACTTCAATTATAGGAACCATCTGTGTGTGTGCATGTGGAAACCAGAGGGGGCTCTCACTGAACCTAGAGTTCACTGATTTGACTAGGGAGGTGTGGCTAGTCCGTG
CCACCTGTCACTACCTGCCAAGGAGGACTAGGATTTCAAAAGTCCACCTCTTTACTCATCTTTAGGTGTGTTGGGGAGCTGGACTCCGGTCCTCATGTCTGTGAGATGAGCTCTTTACTGACTTGACC
ATCTTCCCAGCCCCAAGACCAAGTGGGCAAAATATTCCAGCCATTTACAAAGAGATAACAAATGTCCAATATACAAGGTATCTAGAAGACACAAAGTCCCGAGGAGATATGTTGATGTGCCTGTATAC
AGAGGGCTTAAAACTAAAATGGCTGACACTGTCAAGGGTCTATAGGATACGGACTCTGCATTGTTGTTGGTTAGAAGAGCTACTTTGAAATGACGTCAGGCAGTATGCTTCAGAAACACACTTTACAT
AAGACACGTAACTGATTCTCATGAGTCCAAAGACCTGAATAGGCAAAACCAAATTCTATAAAGGAGAAATAATCCTCAATAGAAAAAGAAATCCAGCTAGTGGTTCCCTCTGCAGGAATGAGCGTGGA
GATTGGCCGGCAAGATATTTGTGGGAGCTTTAATCAGTTGGTGGCTTTTAGATGATAAAGGAGGGAGATCACCGTTGTTTGGCTCCCAAAGATAGTTTGTCAGAACTCACCTAATGATACATTTGCAT
GCCATTGTATGCAAATGTTACCACAAAAGCAAACATCCGAGTATGGAACTCTTAATAATGGCTAATACTGGTTGGAGATGGGGTGAAAGTGTGCGGATGTCTGCAACCTTTCAAACAGCATCCCCGAG
TGGGTTGGTGAATAGAAAAGAACGGGTAAATACGATCAAACCTGGTAAACTGTCACTTGTAGAATCTAGGTGGCGTTGTGTTGTATCATTGTAAAATTCGTTTAATTTTGATGTACTTGAAATTTTTC
TTAAGCTAGTAAAGGTAATTGGGATACTCACTCTGGGTGTGTATTCGATACCCTCCTCTAAAGTTCTTCCTCTCCCGGAGACACAAAGCAAAATTAATGTCTGTTAGTTACTCTCCTCAAAATCACTG
CATCTATTCAACAGAACTGCAAGCTTTTCTAGTTCTGTTTCTGGCAAGTATCGTGTGGGTGGGTCTCCTGGGACCACTCTCTCCAAAGGCGGAGAAATTCTGTTTAGATCGTGGGTGGCTATGAATCC
ATTCCTTCACGCGGATATATTCGATCCCCTGTGGCTAAACGGCTGGGGACCAGGTGTGTCTGAAGGGCACGCAGCGCCCTCTTCTGGCCCCAGAGGGCCAGAACATGCAGACCATCGAGGCTCTCGAC
CTCTTAAACAACCACTCCAGGGATCGGCACAACCGGGTGGAAGCATCGCTGCTCCCTTCCGAGCTCCCGGCGATCGCGGGCGGAGACCTGCGTAGGAGACTGGCCCTGAGGCCAAGAGGCGGACACCG
GGTGGAGTCGCCACGGTTGGCAGCAGCAGGGCTCCACCTGTTGCAGTGTTTGAGCACTCCACAGAGAAGGCAGCTCCGGGCACCGACTTCTGCTCCCAGCCCCACTGGGCAGGGCAAGACCATTTGAG
AAGGGGAGCCCGGGACCATCCTGAACCTGTCGCACAGAGCAGCGGTCCGCCCTCATGCTGCTGCGGAGCCCGTGTGCCCAGTGGAGATCCGAGCCGGCTGATCTGCCCTTCGCACTGTCCCTGCATCC
GTGCGTCTGTCCCAGACCGGTCCCAGCCTCTGAGCCTTGGTTGTTCTGGTTGACAGAGGCTCAGCGGGACATTGTCACCGATACGCAATACAGATCCACCTGGAGAGGCACCGAAGACAGAGGACAGC
CTGTGTCCCAGCCACCACAGCTTGGAAAGCAATGTTCGGAGGAACCCGGACCTTGATGTTAAGCTTACCCACCGATTCTCTCTGGACCCACTACCTTTTCTTCAAGATGAGTTCAAGTTTTATGGAGT
TTGCCTTGAAGGCACGCCACGCCCCCTCCCCAATCTGAGCAAAATTAGGAGCCCGGGTGAACCCCGGTCGCCCGCACCCCCACACCAAGCCGAAGCAGACTCCGTACCCCGACCCTCTGGTCTTCGGC
CTTAAGGAGAACTCCAGAGCGGACGAGGAGGCGGCGGCGACAAAGCGGATTCGAAACCACGAGTCCAGGCGGACGTGGGGAGCTGGCTCCACAGGAACAACGGAGGAGGCGGTGGCCCGGAGATCCAC
GCCGCCTTAGGGAGCGCGCGGCGGGCATGGGCGAGCCCGCAGGCAGAGCGGGCTAAGATCCGCAGAGCCGGATCTTACCAGGGGCGTGGGCACAAGTCCGCGGGCAGCGACCCTCGCGGGGTTGTCCT
CCAGTGCCATGGCTGGCCGCGGTTGCAGCTGCAGCCCCGGCCACCTGAACGAGGACAACGCGCGCTTCCTGCTGCTCGCGGGGCTCATCCTGCTTTACCTGCTGGGCGGCGCCGCAGTCTTCTCCGCG
CTGGAGCTAGCGCAGGAGCTGCAGGCCAAGCAGCGCTGGGAAGAGCGCCTGGCCAACTTCAGCAGGGGCCACAACCTGAGCCGCGAAGAGCTGCGAGGCTTCCTCCGCCACTACGAGGAAGCCACCAA
GGCGGGCATCCGCATGGACAGCGTGCGCCCTCGCTGGGACTTCACGGGCGCCTTCTACTTCGTGGGCACAGTGGTAACTACCATAGGGTTCGGGATGACGACCCCAGCCACAACGGGAGGGAAGGTTT
TTCTGATCTTTTATGGTCTCATTGGATGTGCGAGTACCATCCTCTTCTTCAACCTCTTTCTGGAGCGGCTGATCACCGTCATCGCCTACGTCATGAGAACCTGCCACCACCAGCAGCTGCGCAGACGT
GGGACGGTAGCCCGGGACAACGGGAAGGCCCCTAGAAAGGGCGAGGCAGACAGCCTGGCTGGCTGGAAGCCCTCCGTGTACTACGTCATGCTGATCCTGTGCTTGGCATCAGTAGCCATCTCCTGTGG
AGCCTCGGCTCTGTACACCACCATGGAAGGCTGGAGCTACTTTGACTCCGTCTACTTCTGTTTTGTGGCTTTCAGCACCATTGGCTTCGGGGACCTGGTGAGCAGCCAGAACGCTCAGTATGAGAACG
AAGGGCTCTACCGCTTTGTCAATTTCTTCTTCATCCTCATGGGTGTCTGCTGCATCTACTCCATGTTTAACGTCATCTCCATCCTGATCAAACAGACAGTGAACTGGATCCTGAGGAAACTGGATAGC
GGGTGCTTCCCACAATGCCAAAGAGGACTCCTGCGGTCCAGGAGGAACGTGGTGATGCCGGGCAACATCCGGAACAGGTGCAACATCTCCATAGAGACGGACGGGGTGATGGAAAGTGACACTGATGG
GCGACGTCTCTCGGGGGAGATGATCTCCATGAAGGACACCAACAAGGTCTCCCTGGCCATCCTGCAGAAGCAGTTGTCCGAGATGGCCAATGGTGGACCCCACCAGACCAGCACATCCTCCCGGGATG
ATGAGTTCTCAGGGGGCGTGGGAGCCTTTGCAGTAATGAATAACAGGTTGGCAGAGACCAGTGGGGACAGGTAGGGACCAGAAGTAGCTGCCACATGAAGAAACCCAGGGCAAGTGGGGGATAGGTCA
CTGCCACACCCCCAGGGACCTCAGCTGTGTCTCTGGCTGTTGGAATTAGCATCTCCAGTCCAGCTTTTGAAATCTGACCTTGGCCCTGGGCAGCAGTAACCTCTCAAGGTTGGGGACTGGAGCCATCT
TCCCTGACTCTTACTTTACCCTTGAATTCCCAATTTCGCGTTTGGAATTGTCTGGGGGAGATGGGTTTCCGTCCAGCTTTGATCCCCTACCCCAACCCGGTCATGATCCATCCCTAGGGAGGGAAAGC
CCCGAAAAGCCTGACTCTGTCATGTAGTGTGAATGGCGGCTGAACTTCACCCAGCCCCTCAAGAAAAGGCAGCGAACATTCCCGAATGCCTCTGGGCCTTGTTCTATTATTGGTTCCACTAATAGGGA
AAACATCTAACTTTCTCTTTATATCTGCTTCTCTGTTTGGGAGTCTTGGTTTCGTTTTGTTTTGTTTCCTATCTGACTAGTGTATCTTTTTGGATCTCAGATGATAAGGAAACCAAGTCTACCTTCAA
ACCTCTAAGTTGTAGCAAGATGAAGGCAGTGAGTCAAAGAGGAGGAAAGCTCCCATCTTGTAACTAAAGCCTACCGCTTACTGTGTTCTTTCTGAATGGTTACACGGATTATGTCATTTTACCAGGGC
CTGGAGCCTGCTGTAAAGGCAACCGACTATTTATTAGAACTGAAAATTTAATAAATTCGCATTTTGTTAACTATGA

hide sequence

RefSeq Acc Id:

XM_039112874 ⟹ XP_038968802

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	124,997,381 - 125,074,919 (+)	NCBI
mRatBN7.2	6	119,242,603 - 119,345,292 (+)	NCBI

RefSeq Acc Id:

XM_063262443 ⟹ XP_063118513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	124,972,145 - 125,074,919 (+)	NCBI


Protein RefSeqs	NP_071629	(Get FASTA)	NCBI Sequence Viewer
	XP_006240509	(Get FASTA)	NCBI Sequence Viewer
	XP_038968802	(Get FASTA)	NCBI Sequence Viewer
	XP_063118513	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAG32312	(Get FASTA)	NCBI Sequence Viewer
	EDL81710	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000067310
GenBank Protein	Q9ERS0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071629 ⟸ NM_022293

- UniProtKB:

Q9ERS0 (UniProtKB/Swiss-Prot), M0RCJ1 (UniProtKB/TrEMBL), A6JEG6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAGRGCSCSPGHLNEDNARFLLLAGLILLYLLGGAAVFSALELAQELQAKQRWEERLANFSRGHNLSREELRGFLRHYEEATKAGIRMDSVRPRWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLI
FYGLIGCASTILFFNLFLERLITVIAYVMRTCHHQQLRRRGTVARDNRKAPRKGEADSLAGWKPSVYYVMLILCLASVAISCGASALYTTMEGWSYFDSVYFCFVASSTIGFGDLVSSQNAQYENEGL
YRFVNFFFILMGVCCIYSMFNVISILIKQTVNWILRKLDSGCFPQCQRGLLRSRRNVVMPGNIRNRCNISIETDGVMESDTDGRRLSGEMISMKDTNKVSLAILQKQLSEMANGGPHQTSTSSRDDEF
SGGVGAFAVMNNRLAETSGDR

hide sequence

RefSeq Acc Id:

XP_006240509 ⟸ XM_006240447

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAGRGCSCSPGHLNEDNARFLLLAGLILLYLLGGAAVFSALELAQELQAKQRWEERLANFSRGH
NLSREELRGFLRHYEEATKAGIRMDSVRPRWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLIFYGLIGCASTILFFNLFLERLITVIAYVMRTCHHQQLRRRGTVARDNGKAPRKGEADSLAGWKP
SVYYVMLILCLASVAISCGASALYTTMEGWSYFDSVYFCFVAFSTIGFGDLVSSQNAQYENEGLYRFVNFFFILMGVCCIYSMFNVISILIKQTVNWILRKLDSGCFPQCQRGLLRSRRNVVMPGNIR
NRCNISIETDGVMESDTDGRRLSGEMISMKDTNKVSLAILQKQLSEMANGGPHQTSTSSRDDEFSGGVGAFAVMNNRLAETSGDR

hide sequence

Ensembl Acc Id:

ENSRNOP00000067310 ⟸ ENSRNOT00000075794

RefSeq Acc Id:	XP_038968802 ⟸ XM_039112874
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000077400 ⟸ ENSRNOT00000101370

Protein Domains

Potassium channel

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9ERS0-F1-model_v2	AlphaFold	Q9ERS0	1-405	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-36506	BioCyc
Ensembl Genes	ENSRNOG00000047363	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000075794	ENTREZGENE
Gene3D-CATH	1.10.287.70	UniProtKB/Swiss-Prot
InterPro	2pore_dom_K_chnl	UniProtKB/Swiss-Prot
	2pore_dom_K_chnl_THIK	UniProtKB/Swiss-Prot
	K_chnl_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:64120	UniProtKB/Swiss-Prot
NCBI Gene	64120	ENTREZGENE
PANTHER	POTASSIUM CHANNEL SUBFAMILY K MEMBER 13	UniProtKB/Swiss-Prot
	PTHR11003	UniProtKB/Swiss-Prot
Pfam	Ion_trans_2	UniProtKB/Swiss-Prot
PhenoGen	Kcnk13	PhenoGen
PRINTS	2POREKCHANEL	UniProtKB/Swiss-Prot
	THIKCHANNEL	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000047363	RatGTEx
Superfamily-SCOP	Voltage-gated potassium channels	UniProtKB/Swiss-Prot
UniProt	A0A8I5YCC6_RAT	UniProtKB/TrEMBL
	A6JEG6	ENTREZGENE, UniProtKB/TrEMBL
	KCNKD_RAT	UniProtKB/Swiss-Prot
	M0RCJ1	ENTREZGENE, UniProtKB/TrEMBL
	Q9ERS0	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-11	Kcnk13	potassium two pore domain channel subfamily K member 13	Kcnk13	potassium channel, two pore domain subfamily K, member 13	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-01-26	Kcnk13	potassium channel, two pore domain subfamily K, member 13	Kcnk13	potassium channel, subfamily K, member 13	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Kcnk13	potassium channel, subfamily K, member 13			Symbol and Name status set to approved	70586	APPROVED

Note Type	Note	Reference
gene_expression	restricted to only a few brain regions and nuclei	67928
gene_expression	substantial levels detected only in granule cell layer of the olfactory bulb, in the olfactory tubercle, the lateral septum, and in distinct hypothalamic and thalamic nuclei	67928

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar