Symbol:
Ero1a
Name:
endoplasmic reticulum oxidoreductase 1 alpha
RGD ID:
621713
Description:
Predicted to enable protein-disulfide reductase activity. Involved in cellular response to hypoxia. Located in dendrite. Orthologous to human ERO1A (endoplasmic reticulum oxidoreductase 1 alpha); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidoreductase alpha; endoplasmic reticulum oxidoreductin-1-like protein; ERO1-L; ERO1-L-alpha; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Ero1l; global ischemia-induced protein 11; LOC360278; oxidoreductin-1-L-alpha
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 20,974,771 - 21,010,170 (-) NCBI GRCr8 mRatBN7.2 15 18,495,037 - 18,530,440 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 18,492,945 - 18,530,478 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 15 21,289,698 - 21,325,207 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 15 22,246,643 - 22,282,158 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 15 20,503,217 - 20,538,731 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 15 19,619,947 - 19,655,381 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 19,619,973 - 19,655,381 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 23,585,168 - 23,620,355 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 21,169,438 - 21,205,536 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 15 21,169,450 - 21,205,536 NCBI Celera 15 18,923,324 - 18,958,689 (-) NCBI Celera Cytogenetic Map 15 p14 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ero1a Rat (1->4)-beta-D-glucan multiple interactions ISO Ero1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ERO1L mRNA CTD PMID:36331819 Ero1a Rat 1,1-dichloroethene increases expression ISO Ero1a (Mus musculus) 6480464 vinylidene chloride results in increased expression of ERO1A mRNA CTD PMID:26682919 Ero1a Rat 1,2-dimethylhydrazine decreases expression ISO Ero1a (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of ERO1L mRNA CTD PMID:22206623 Ero1a Rat 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of ERO1L mRNA CTD PMID:32145629 Ero1a Rat 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO ERO1A (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of ERO1A mRNA CTD PMID:29581250 Ero1a Rat 1H-pyrazole increases expression ISO Ero1a (Mus musculus) 6480464 pyrazole results in increased expression of ERO1A mRNA CTD PMID:17945193 Ero1a Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ERO1A mRNA CTD PMID:25529477 and PMID:33387578 Ero1a Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ero1a (Mus musculus) 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ERO1A mRNA CTD PMID:25975270 Ero1a Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of ERO1A mRNA CTD PMID:21346803 Ero1a Rat 2-hydroxypropanoic acid decreases expression ISO ERO1A (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ERO1A mRNA CTD PMID:30851411 Ero1a Rat 2-palmitoylglycerol increases expression ISO ERO1A (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of ERO1A mRNA CTD PMID:37199045 Ero1a Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 Ero1a Rat 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of ERO1A protein CTD PMID:26072098 Ero1a Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ERO1A (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ERO1A mRNA CTD PMID:28628672 Ero1a Rat 4,4'-sulfonyldiphenol multiple interactions ISO ERO1A (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ERO1A mRNA CTD PMID:28628672 Ero1a Rat 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ERO1A mRNA CTD PMID:36041667 Ero1a Rat adefovir pivoxil increases expression ISO ERO1A (Homo sapiens) 6480464 adefovir dipivoxil results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat aflatoxin B1 decreases expression ISO Ero1a (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of ERO1A mRNA CTD PMID:19770486 Ero1a Rat aldehydo-D-glucose decreases expression ISO Ero1a (Mus musculus) 6480464 Glucose results in decreased expression of ERO1A mRNA CTD PMID:17178593 Ero1a Rat aldehydo-D-glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein] and Metformin inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 Ero1a Rat aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of ERO1A protein CTD PMID:34801538 Ero1a Rat all-trans-retinoic acid increases expression ISO ERO1A (Homo sapiens) 6480464 Tretinoin results in increased expression of ERO1A mRNA CTD PMID:33167477 Ero1a Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ERO1A mRNA CTD PMID:16483693 Ero1a Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of ERO1A mRNA CTD PMID:30779732 Ero1a Rat antimycin A increases expression ISO Ero1a (Mus musculus) 6480464 Antimycin A results in increased expression of ERO1A mRNA CTD PMID:19304788 Ero1a Rat apocynin multiple interactions ISO Ero1a (Mus musculus) 6480464 acetovanillone inhibits the reaction [arsenite results in increased expression of ERO1A protein] CTD PMID:37659621 Ero1a Rat aristolochic acid A decreases expression ISO ERO1A (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ERO1A mRNA CTD PMID:33212167 Ero1a Rat Aroclor 1254 decreases expression ISO Ero1a (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ERO1A mRNA CTD PMID:23650126 Ero1a Rat arsane multiple interactions ISO ERO1A (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ERO1A mRNA CTD PMID:32525701 Ero1a Rat arsenic atom multiple interactions ISO ERO1A (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ERO1A mRNA CTD PMID:32525701 Ero1a Rat arsenite(3-) increases expression ISO Ero1a (Mus musculus) 6480464 arsenite results in increased expression of ERO1A protein CTD PMID:35964836 and PMID:37659621 Ero1a Rat arsenite(3-) multiple interactions ISO ERO1A (Homo sapiens) 6480464 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [arsenite results in increased expression of ERO1A protein] and 2-aminoethoxydiphenyl borate inhibits the reaction [arsenite results in increased expression of ERO1A protein] CTD PMID:35964836 and PMID:37659621 Ero1a Rat arsenite(3-) affects response to substance ISO Ero1a (Mus musculus) 6480464 ERO1A protein affects the susceptibility to arsenite CTD PMID:35964836 Ero1a Rat arsenite(3-) increases expression ISO ERO1A (Homo sapiens) 6480464 arsenite results in increased expression of ERO1A protein CTD PMID:35964836 and PMID:37659621 Ero1a Rat arsenite(3-) multiple interactions ISO Ero1a (Mus musculus) 6480464 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [arsenite results in increased expression of ERO1A protein] more ... CTD PMID:35964836 and PMID:37659621 Ero1a Rat benzene-1,2,4-triol increases expression ISO ERO1A (Homo sapiens) 6480464 hydroxyhydroquinone results in increased expression of ERO1A mRNA CTD PMID:17572062 Ero1a Rat benzo[a]pyrene diol epoxide I affects expression ISO ERO1A (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 Ero1a Rat beta-lapachone increases expression ISO ERO1A (Homo sapiens) 6480464 beta-lapachone results in increased expression of ERO1A mRNA CTD PMID:38218311 Ero1a Rat bis(2-ethylhexyl) phthalate decreases expression ISO ERO1A (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of ERO1A protein CTD PMID:31163220 Ero1a Rat bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of ERO1A protein CTD PMID:37979351 Ero1a Rat bis(2-ethylhexyl) phthalate affects expression ISO Ero1a (Mus musculus) 6480464 Diethylhexyl Phthalate affects the expression of ERO1A mRNA CTD PMID:21318169 Ero1a Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ERO1A mRNA and bisphenol A results in increased expression of ERO1L mRNA CTD PMID:25181051 and PMID:32145629 Ero1a Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ERO1A mRNA CTD PMID:36041667 Ero1a Rat bisphenol A decreases expression ISO ERO1A (Homo sapiens) 6480464 bisphenol A results in decreased expression of ERO1A protein CTD PMID:31675489 Ero1a Rat bisphenol A affects expression ISO ERO1A (Homo sapiens) 6480464 bisphenol A affects the expression of ERO1A mRNA CTD PMID:30903817 Ero1a Rat bisphenol AF increases expression ISO ERO1A (Homo sapiens) 6480464 bisphenol AF results in increased expression of ERO1A protein CTD PMID:34186270 Ero1a Rat bisphenol F increases expression ISO Ero1a (Mus musculus) 6480464 bisphenol F results in increased expression of ERO1A mRNA CTD PMID:38685157 Ero1a Rat bisphenol F multiple interactions EXP 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of ERO1A mRNA CTD PMID:36041667 Ero1a Rat cadmium dichloride affects expression ISO ERO1A (Homo sapiens) 6480464 Cadmium Chloride affects the expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat calcitriol increases expression ISO ERO1A (Homo sapiens) 6480464 Calcitriol results in increased expression of ERO1A mRNA CTD PMID:21592394 Ero1a Rat calcitriol multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of ERO1A mRNA CTD PMID:21592394 Ero1a Rat calyculin a increases expression ISO Ero1a (Mus musculus) 6480464 calyculin A results in increased expression of ERO1A mRNA CTD PMID:25270620 Ero1a Rat carbon monoxide increases expression EXP 6480464 Carbon Monoxide results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat chloroacetaldehyde increases expression ISO ERO1A (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat chlorogenic acid multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 Ero1a Rat chlorpromazine increases expression EXP 6480464 Chlorpromazine results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat chromium(6+) affects expression ISO Ero1a (Mus musculus) 6480464 chromium hexavalent ion affects the expression of ERO1A mRNA CTD PMID:28472532 Ero1a Rat chromium(6+) multiple interactions ISO ERO1A (Homo sapiens) 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of ERO1A mRNA CTD PMID:38479592 Ero1a Rat cidofovir anhydrous increases expression ISO ERO1A (Homo sapiens) 6480464 Cidofovir results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat cobalt atom increases expression EXP 6480464 Cobalt results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of ERO1A mRNA CTD PMID:24386269 Ero1a Rat cobalt dichloride increases expression ISO ERO1A (Homo sapiens) 6480464 cobaltous chloride results in increased expression of ERO1A mRNA CTD PMID:19320972 and PMID:19376846 Ero1a Rat cyclosporin A decreases expression ISO ERO1A (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ERO1A mRNA CTD PMID:21163907 Ero1a Rat cyclosporin A increases expression ISO Ero1a (Mus musculus) 6480464 Cyclosporine results in increased expression of ERO1A mRNA CTD PMID:23830897 and PMID:23958496 Ero1a Rat cyclosporin A increases expression ISO ERO1A (Homo sapiens) 6480464 Cyclosporine results in increased expression of ERO1A mRNA CTD PMID:20106945 more ... Ero1a Rat D-glucose decreases expression ISO Ero1a (Mus musculus) 6480464 Glucose results in decreased expression of ERO1A mRNA CTD PMID:17178593 Ero1a Rat D-glucose increases expression EXP 6480464 Glucose results in increased expression of ERO1A protein CTD PMID:34801538 Ero1a Rat D-glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein] and Metformin inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 Ero1a Rat decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of ERO1A mRNA CTD PMID:23640034 Ero1a Rat decabromodiphenyl ether decreases expression ISO ERO1A (Homo sapiens) 6480464 decabromobiphenyl ether results in decreased expression of ERO1A protein CTD PMID:31675489 Ero1a Rat deguelin increases expression ISO ERO1A (Homo sapiens) 6480464 deguelin results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat desferrioxamine B increases expression ISO ERO1A (Homo sapiens) 6480464 Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat desferrioxamine B increases expression ISO Ero1a (Mus musculus) 6480464 Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat dexamethasone multiple interactions ISO ERO1A (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ERO1A mRNA CTD PMID:28628672 Ero1a Rat dextran sulfate multiple interactions ISO Ero1a (Mus musculus) 6480464 evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ERO1A protein] CTD PMID:35362542 Ero1a Rat dextran sulfate decreases expression ISO Ero1a (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of ERO1A protein CTD PMID:35362542 Ero1a Rat Dibutyl phosphate affects expression ISO ERO1A (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ERO1A mRNA CTD PMID:37042841 Ero1a Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of ERO1A mRNA CTD PMID:21266533 Ero1a Rat diclofenac increases expression ISO Ero1a (Mus musculus) 6480464 Diclofenac results in increased expression of ERO1A mRNA CTD PMID:26934552 Ero1a Rat dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of ERO1A mRNA and Oxygen deficiency results in increased expression of ERO1A protein CTD PMID:12752442 Ero1a Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of ERO1A mRNA CTD PMID:33729688 Ero1a Rat dioxygen increases expression ISO Ero1a (Mus musculus) 6480464 Oxygen deficiency results in increased expression of ERO1A and Oxygen deficiency results in increased expression of ERO1A mRNA CTD PMID:12752442 and PMID:20880076 Ero1a Rat dioxygen increases expression ISO ERO1A (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of ERO1A and Oxygen deficiency results in increased expression of ERO1A mRNA CTD PMID:12752442 more ... Ero1a Rat diuron decreases expression ISO ERO1A (Homo sapiens) 6480464 Diuron results in decreased expression of ERO1A mRNA CTD PMID:35967413 Ero1a Rat dorsomorphin multiple interactions ISO ERO1A (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ERO1A mRNA CTD PMID:27188386 Ero1a Rat doxorubicin decreases expression ISO ERO1A (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ERO1A mRNA CTD PMID:29803840 Ero1a Rat endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of ERO1A mRNA CTD PMID:31464424 Ero1a Rat enzyme inhibitor multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ERO1A protein CTD PMID:23301498 Ero1a Rat ethanol affects splicing ISO Ero1a (Mus musculus) 6480464 Ethanol affects the splicing of ERO1A mRNA CTD PMID:30319688 Ero1a Rat ethanol multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of ERO1A mRNA CTD PMID:23378141 Ero1a Rat ethidium multiple interactions ISO Ero1a (Mus musculus) 6480464 [Pyruvic Acid co-treated with Uridine co-treated with Ethidium] inhibits the reaction [Rotenone inhibits the reaction [arsenite results in increased expression of ERO1A protein]] CTD PMID:37659621 Ero1a Rat ethyl methanesulfonate decreases expression ISO ERO1A (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of ERO1A mRNA CTD PMID:23649840 Ero1a Rat Evodiamine multiple interactions ISO Ero1a (Mus musculus) 6480464 evodiamine inhibits the reaction [Dextran Sulfate results in decreased expression of ERO1A protein] CTD PMID:35362542 Ero1a Rat fenofibrate increases expression EXP 6480464 Fenofibrate results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat fenpyroximate increases expression ISO ERO1A (Homo sapiens) 6480464 fenpyroximate results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat folic acid multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of ERO1A mRNA CTD PMID:23378141 Ero1a Rat formaldehyde decreases expression ISO ERO1A (Homo sapiens) 6480464 Formaldehyde results in decreased expression of ERO1A mRNA CTD PMID:23649840 Ero1a Rat furfural multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of ERO1A protein CTD PMID:38598786 Ero1a Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ERO1A mRNA CTD PMID:22061828 Ero1a Rat glucose decreases expression ISO Ero1a (Mus musculus) 6480464 Glucose results in decreased expression of ERO1A mRNA CTD PMID:17178593 Ero1a Rat glucose multiple interactions EXP 6480464 Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein] and Metformin inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 Ero1a Rat glucose increases expression EXP 6480464 Glucose results in increased expression of ERO1A protein CTD PMID:34801538 Ero1a Rat gold atom increases expression ISO ERO1A (Homo sapiens) 6480464 Gold results in increased expression of ERO1A mRNA CTD PMID:29705079 Ero1a Rat gold(0) increases expression ISO ERO1A (Homo sapiens) 6480464 Gold results in increased expression of ERO1A mRNA CTD PMID:29705079 Ero1a Rat homocysteine decreases expression ISO ERO1A (Homo sapiens) 6480464 Homocysteine results in decreased expression of ERO1A protein CTD PMID:22964297 Ero1a Rat ifosfamide increases expression ISO ERO1A (Homo sapiens) 6480464 Ifosfamide results in increased expression of ERO1A mRNA CTD PMID:25596134 Ero1a Rat indometacin multiple interactions ISO ERO1A (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ERO1A mRNA CTD PMID:28628672 Ero1a Rat ivermectin decreases expression ISO ERO1A (Homo sapiens) 6480464 Ivermectin results in decreased expression of ERO1A protein CTD PMID:32959892 Ero1a Rat ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of ERO1A mRNA CTD PMID:37077353 Ero1a Rat lead(0) affects expression ISO ERO1A (Homo sapiens) 6480464 Lead affects the expression of ERO1A mRNA CTD PMID:28903495 Ero1a Rat lipopolysaccharide increases expression ISO Ero1a (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of ERO1A mRNA CTD PMID:27339419 Ero1a Rat metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Glucose results in increased expression of ERO1A protein] CTD PMID:34801538 Ero1a Rat methyl methanesulfonate decreases expression ISO ERO1A (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of ERO1A mRNA CTD PMID:23649840 Ero1a Rat mono(2-ethylhexyl) phthalate multiple interactions ISO Ero1a (Mus musculus) 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:37979351 Ero1a Rat mono(2-ethylhexyl) phthalate increases expression ISO Ero1a (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of ERO1A protein CTD PMID:37979351 Ero1a Rat nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of ERO1A mRNA CTD PMID:22110744 Ero1a Rat nickel dichloride multiple interactions ISO Ero1a (Mus musculus) 6480464 HIF1A affects the reaction [nickel chloride results in increased expression of ERO1A mRNA] CTD PMID:12729255 Ero1a Rat nickel dichloride increases expression ISO Ero1a (Mus musculus) 6480464 nickel chloride results in increased expression of ERO1A mRNA CTD PMID:12729255 Ero1a Rat nickel subsulfide affects expression ISO Ero1a (Mus musculus) 6480464 nickel subsulfide affects the expression of ERO1A mRNA CTD PMID:12729255 Ero1a Rat NMS-873 increases expression ISO ERO1A (Homo sapiens) 6480464 NMS-873 results in increased expression of ERO1A protein CTD PMID:29693262 Ero1a Rat ochratoxin A decreases expression ISO ERO1A (Homo sapiens) 6480464 ochratoxin A results in decreased expression of ERO1A mRNA CTD PMID:30559759 Ero1a Rat okadaic acid increases expression EXP 6480464 Okadaic Acid results in increased expression of ERO1A protein CTD PMID:26732598 Ero1a Rat paracetamol decreases expression ISO ERO1A (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ERO1A mRNA CTD PMID:21420995 Ero1a Rat paracetamol affects expression ISO Ero1a (Mus musculus) 6480464 Acetaminophen affects the expression of ERO1A mRNA CTD PMID:17562736 Ero1a Rat parthenolide decreases expression ISO ERO1A (Homo sapiens) 6480464 parthenolide results in decreased expression of ERO1A protein CTD PMID:36477977 Ero1a Rat perfluorohexanesulfonic acid decreases expression ISO Ero1a (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of ERO1A mRNA CTD PMID:37995155 Ero1a Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ero1a (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ERO1L mRNA CTD PMID:36331819 Ero1a Rat perfluorooctanoic acid increases expression ISO Ero1a (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of ERO1A protein CTD PMID:37044272 Ero1a Rat picoxystrobin increases expression ISO ERO1A (Homo sapiens) 6480464 picoxystrobin results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat propiconazole increases expression ISO Ero1a (Mus musculus) 6480464 propiconazole results in increased expression of ERO1A mRNA CTD PMID:21278054 Ero1a Rat pyruvic acid multiple interactions ISO Ero1a (Mus musculus) 6480464 [Pyruvic Acid co-treated with Uridine co-treated with Ethidium] inhibits the reaction [Rotenone inhibits the reaction [arsenite results in increased expression of ERO1A protein]] CTD PMID:37659621 Ero1a Rat rac-lactic acid decreases expression ISO ERO1A (Homo sapiens) 6480464 Lactic Acid results in decreased expression of ERO1A mRNA CTD PMID:30851411 Ero1a Rat resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of ERO1A mRNA CTD PMID:19228061 Ero1a Rat resveratrol multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ERO1A mRNA CTD PMID:23557933 Ero1a Rat resveratrol multiple interactions ISO Ero1a (Mus musculus) 6480464 ERO1A protein inhibits the reaction [Resveratrol results in decreased secretion of ADIPOQ protein] CTD PMID:17452443 Ero1a Rat rotenone increases expression ISO ERO1A (Homo sapiens) 6480464 Rotenone results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat rotenone multiple interactions ISO Ero1a (Mus musculus) 6480464 [Pyruvic Acid co-treated with Uridine co-treated with Ethidium] inhibits the reaction [Rotenone inhibits the reaction [arsenite results in increased expression of ERO1A protein]] and Rotenone inhibits the reaction [arsenite results in increased expression of ERO1A protein] CTD PMID:37659621 Ero1a Rat rotenone increases expression ISO Ero1a (Mus musculus) 6480464 Rotenone results in increased expression of ERO1A mRNA CTD PMID:19304788 Ero1a Rat SB 431542 multiple interactions ISO ERO1A (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ERO1A mRNA CTD PMID:27188386 Ero1a Rat serpentine asbestos increases expression ISO ERO1A (Homo sapiens) 6480464 Asbestos and Serpentine results in increased expression of ERO1A mRNA CTD PMID:29523930 Ero1a Rat silver atom increases expression ISO Ero1a (Mus musculus) 6480464 Silver results in increased expression of ERO1A mRNA CTD PMID:27131904 Ero1a Rat silver(0) increases expression ISO Ero1a (Mus musculus) 6480464 Silver results in increased expression of ERO1A mRNA CTD PMID:27131904 Ero1a Rat sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [TSC2 gene mutant form results in increased expression of ERO1A mRNA] CTD PMID:19420259 Ero1a Rat sodium arsenate multiple interactions ISO ERO1A (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of ERO1A mRNA CTD PMID:32525701 Ero1a Rat sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of ERO1A protein CTD PMID:29459688 Ero1a Rat sodium chloride multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of ERO1A protein CTD PMID:38598786 Ero1a Rat sodium fluoride decreases expression ISO Ero1a (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of ERO1A protein CTD PMID:28918527 Ero1a Rat sotorasib multiple interactions ISO ERO1A (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERO1A mRNA CTD PMID:36139627 Ero1a Rat succimer multiple interactions ISO Ero1a (Mus musculus) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ERO1A mRNA CTD PMID:26378955 Ero1a Rat sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of ERO1A protein CTD PMID:37385402 Ero1a Rat sunitinib increases expression ISO ERO1A (Homo sapiens) 6480464 Sunitinib results in increased expression of ERO1A mRNA CTD PMID:31533062 Ero1a Rat T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of ERO1A mRNA CTD PMID:26141394 Ero1a Rat tacrolimus hydrate increases expression ISO Ero1a (Mus musculus) 6480464 Tacrolimus results in increased expression of ERO1A mRNA CTD PMID:23958496 Ero1a Rat tebufenpyrad increases expression ISO ERO1A (Homo sapiens) 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat temozolomide decreases expression ISO ERO1A (Homo sapiens) 6480464 Temozolomide results in decreased expression of ERO1A mRNA CTD PMID:31758290 Ero1a Rat Tesaglitazar increases expression EXP 6480464 tesaglitazar results in increased expression of ERO1A mRNA CTD PMID:21515302 Ero1a Rat testosterone increases expression ISO ERO1A (Homo sapiens) 6480464 Testosterone results in increased expression of ERO1A mRNA CTD PMID:21592394 Ero1a Rat testosterone multiple interactions ISO ERO1A (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of ERO1A mRNA CTD PMID:21592394 Ero1a Rat tetrachloromethane increases expression ISO Ero1a (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ERO1A mRNA CTD PMID:27339419 and PMID:31919559 Ero1a Rat tetrathiomolybdate(2-) decreases expression ISO ERO1A (Homo sapiens) 6480464 tetrathiomolybdate results in decreased expression of ERO1A mRNA CTD PMID:37290678 Ero1a Rat thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of ERO1A protein CTD PMID:28315715 Ero1a Rat thapsigargin multiple interactions ISO Ero1a (Mus musculus) 6480464 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Thapsigargin results in increased expression of ERO1A protein] CTD PMID:35964836 Ero1a Rat thapsigargin multiple interactions ISO ERO1A (Homo sapiens) 6480464 2-(4-chlorophenoxy)-N-(4-(2-(4-chlorophenoxy)acetamido)cyclohexyl)acetamide inhibits the reaction [Thapsigargin results in increased expression of ERO1A protein] CTD PMID:35964836 Ero1a Rat thapsigargin increases expression ISO Ero1a (Mus musculus) 6480464 Thapsigargin results in increased expression of ERO1A protein CTD PMID:35964836 Ero1a Rat thapsigargin increases expression ISO ERO1A (Homo sapiens) 6480464 Thapsigargin results in increased expression of ERO1A protein CTD PMID:35964836 Ero1a Rat thifluzamide increases expression ISO ERO1A (Homo sapiens) 6480464 thifluzamide results in increased expression of ERO1A mRNA CTD PMID:33512557 Ero1a Rat trametinib multiple interactions ISO ERO1A (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of ERO1A mRNA CTD PMID:36139627 Ero1a Rat trichostatin A increases expression ISO ERO1A (Homo sapiens) 6480464 trichostatin A results in increased expression of ERO1A mRNA CTD PMID:24935251 Ero1a Rat trimellitic anhydride increases expression ISO Ero1a (Mus musculus) 6480464 trimellitic anhydride results in increased expression of ERO1A mRNA CTD PMID:19042947 Ero1a Rat triphenyl phosphate affects expression ISO ERO1A (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ERO1A mRNA CTD PMID:37042841 Ero1a Rat troglitazone multiple interactions ISO Ero1a (Mus musculus) 6480464 [Troglitazone results in increased activity of PPARG protein] which results in increased expression of ERO1A mRNA CTD PMID:17452443 Ero1a Rat tunicamycin increases expression ISO Ero1a (Mus musculus) 6480464 Tunicamycin results in increased expression of ERO1A mRNA CTD PMID:12752442 Ero1a Rat uridine multiple interactions ISO Ero1a (Mus musculus) 6480464 [Pyruvic Acid co-treated with Uridine co-treated with Ethidium] inhibits the reaction [Rotenone inhibits the reaction [arsenite results in increased expression of ERO1A protein]] CTD PMID:37659621 Ero1a Rat valproic acid increases expression ISO ERO1A (Homo sapiens) 6480464 Valproic Acid results in increased expression of ERO1A mRNA CTD PMID:23179753 more ... Ero1a Rat valproic acid multiple interactions ISO ERO1A (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ERO1A mRNA CTD PMID:27188386 Ero1a Rat valproic acid affects expression ISO ERO1A (Homo sapiens) 6480464 Valproic Acid affects the expression of ERO1A mRNA CTD PMID:25979313 Ero1a Rat valproic acid decreases methylation ISO ERO1A (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ERO1A gene CTD PMID:29154799 Ero1a Rat zoledronic acid increases expression ISO ERO1A (Homo sapiens) 6480464 Zoledronic Acid results in increased expression of ERO1A mRNA CTD PMID:24714768 and PMID:25596134
Imported Annotations - KEGG (archival)
(1->4)-beta-D-glucan (ISO) 1,1-dichloroethene (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (EXP) 17beta-hydroxy-5alpha-androstan-3-one (ISO) 1H-pyrazole (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,6-dinitrotoluene (EXP) 2-hydroxypropanoic acid (ISO) 2-palmitoylglycerol (ISO) 3,3',4,4',5-pentachlorobiphenyl (EXP) 3-chloropropane-1,2-diol (EXP) 3-isobutyl-1-methyl-7H-xanthine (ISO) 4,4'-sulfonyldiphenol (EXP,ISO) adefovir pivoxil (ISO) aflatoxin B1 (ISO) aldehydo-D-glucose (EXP,ISO) all-trans-retinoic acid (ISO) ammonium chloride (EXP) amphetamine (EXP) antimycin A (ISO) apocynin (ISO) aristolochic acid A (ISO) Aroclor 1254 (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) benzene-1,2,4-triol (ISO) benzo[a]pyrene diol epoxide I (ISO) beta-lapachone (ISO) bis(2-ethylhexyl) phthalate (EXP,ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) bisphenol F (EXP,ISO) cadmium dichloride (ISO) calcitriol (ISO) calyculin a (ISO) carbon monoxide (EXP) chloroacetaldehyde (ISO) chlorogenic acid (EXP) chlorpromazine (EXP) chromium(6+) (ISO) cidofovir anhydrous (ISO) cobalt atom (EXP) cobalt dichloride (EXP,ISO) cyclosporin A (ISO) D-glucose (EXP,ISO) decabromodiphenyl ether (EXP,ISO) deguelin (ISO) desferrioxamine B (EXP,ISO) dexamethasone (ISO) dextran sulfate (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) diclofenac (ISO) dioxygen (EXP,ISO) diuron (ISO) dorsomorphin (ISO) doxorubicin (ISO) endosulfan (EXP) enzyme inhibitor (ISO) ethanol (ISO) ethidium (ISO) ethyl methanesulfonate (ISO) Evodiamine (ISO) fenofibrate (EXP) fenpyroximate (ISO) folic acid (ISO) formaldehyde (ISO) furfural (ISO) gentamycin (EXP) glucose (EXP,ISO) gold atom (ISO) gold(0) (ISO) homocysteine (ISO) ifosfamide (ISO) indometacin (ISO) ivermectin (ISO) ketoconazole (EXP) lead(0) (ISO) lipopolysaccharide (ISO) metformin (EXP) methyl methanesulfonate (ISO) mono(2-ethylhexyl) phthalate (ISO) nickel dichloride (EXP,ISO) nickel subsulfide (ISO) NMS-873 (ISO) ochratoxin A (ISO) okadaic acid (EXP) paracetamol (ISO) parthenolide (ISO) perfluorohexanesulfonic acid (ISO) perfluorooctane-1-sulfonic acid (ISO) perfluorooctanoic acid (ISO) picoxystrobin (ISO) propiconazole (ISO) pyruvic acid (ISO) rac-lactic acid (ISO) resveratrol (EXP,ISO) rotenone (ISO) SB 431542 (ISO) serpentine asbestos (ISO) silver atom (ISO) silver(0) (ISO) sirolimus (EXP) sodium arsenate (ISO) sodium arsenite (EXP) sodium chloride (ISO) sodium fluoride (ISO) sotorasib (ISO) succimer (ISO) sulforaphane (EXP) sunitinib (ISO) T-2 toxin (EXP) tacrolimus hydrate (ISO) tebufenpyrad (ISO) temozolomide (ISO) Tesaglitazar (EXP) testosterone (ISO) tetrachloromethane (ISO) tetrathiomolybdate(2-) (ISO) thapsigargin (EXP,ISO) thifluzamide (ISO) trametinib (ISO) trichostatin A (ISO) trimellitic anhydride (ISO) triphenyl phosphate (ISO) troglitazone (ISO) tunicamycin (ISO) uridine (ISO) valproic acid (ISO) zoledronic acid (ISO)
Biological Process
apoptotic process (IEA) brown fat cell differentiation (IEA,ISO) cell redox homeostasis (IEA,ISO,ISS) cellular response to hypoxia (IEP) chaperone cofactor-dependent protein refolding (IEA,ISO) collagen fibril organization (IEA,ISO) endoplasmic reticulum unfolded protein response (IEA,ISO) extracellular matrix organization (IEA,ISO) intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (IEA,ISO,ISS) L-ascorbic acid metabolic process (IEA,ISO) peptidyl-proline hydroxylation to 4-hydroxy-L-proline (ISO) protein folding (IEA,ISO,ISS) protein folding in endoplasmic reticulum (IBA,IEA) protein maturation (IEA,ISO) release of sequestered calcium ion into cytosol (IEA,ISO,ISS) response to endoplasmic reticulum stress (IEA,ISO,ISS) response to oxidative stress (IEA,ISO) skeletal muscle tissue development (IEA,ISO) transforming growth factor beta receptor signaling pathway (IEA,ISO)
1.
Ero1-L, an ischemia-inducible gene from rat brain with homology to global ischemia-induced gene 11 (Giig11), is localized to neuronal dendrites by a dispersed identifier (ID) element-dependent mechanism.
Chen D, etal., J Neurochem 2003 May;85(3):670-9.
2.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.
The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1-Lalpha.
Gess B, etal., Eur J Biochem. 2003 May;270(10):2228-35.
4.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
5.
Accelerated senescence in kidneys of low-birth-weight rats after catch-up growth.
Luyckx VA, etal., Am J Physiol Renal Physiol. 2009 Dec;297(6):F1697-705. doi: 10.1152/ajprenal.00462.2009. Epub 2009 Oct 14.
6.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
7.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
9.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
10.
Comprehensive gene review and curation
RGD comprehensive gene curation
11.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Ero1a Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 20,974,771 - 21,010,170 (-) NCBI GRCr8 mRatBN7.2 15 18,495,037 - 18,530,440 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 18,492,945 - 18,530,478 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 15 21,289,698 - 21,325,207 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 15 22,246,643 - 22,282,158 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 15 20,503,217 - 20,538,731 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 15 19,619,947 - 19,655,381 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 19,619,973 - 19,655,381 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 23,585,168 - 23,620,355 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 21,169,438 - 21,205,536 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 15 21,169,450 - 21,205,536 NCBI Celera 15 18,923,324 - 18,958,689 (-) NCBI Celera Cytogenetic Map 15 p14 NCBI
ERO1A Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 14 52,639,915 - 52,695,558 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 14 52,639,915 - 52,695,900 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 14 53,106,633 - 53,162,276 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 14 52,178,355 - 52,232,169 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 14 52,178,356 - 52,232,169 NCBI Celera 14 32,976,214 - 33,030,020 (-) NCBI Celera Cytogenetic Map 14 q22.1 NCBI HuRef 14 33,269,409 - 33,323,505 (-) NCBI HuRef CHM1_1 14 53,047,533 - 53,101,335 (-) NCBI CHM1_1 T2T-CHM13v2.0 14 46,847,757 - 46,903,365 (-) NCBI T2T-CHM13v2.0
Ero1a Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 14 45,520,544 - 45,556,029 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 14 45,520,544 - 45,556,228 (-) Ensembl GRCm39 Ensembl GRCm38 14 45,283,087 - 45,318,572 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 14 45,283,087 - 45,318,771 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 14 45,903,996 - 45,938,202 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 14 44,206,198 - 44,240,404 (-) NCBI MGSCv36 mm8 Celera 14 41,464,909 - 41,498,352 (-) NCBI Celera Cytogenetic Map 14 C1 NCBI cM Map 14 22.86 NCBI
Ero1a Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955409 10,502,554 - 10,530,376 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955409 10,495,892 - 10,533,383 (+) NCBI ChiLan1.0 ChiLan1.0
ERO1A Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 15 53,770,587 - 53,826,868 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 14 52,987,098 - 53,043,159 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 14 33,236,087 - 33,292,127 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 14 51,520,048 - 51,575,792 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 14 51,520,048 - 51,575,798 (-) Ensembl panpan1.1 panPan2
ERO1A Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 8 28,864,642 - 28,913,864 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 8 28,864,925 - 28,914,368 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 8 28,609,553 - 28,658,814 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 8 29,030,663 - 29,080,527 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 8 29,029,758 - 29,081,013 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 8 28,704,719 - 28,754,465 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 8 28,776,955 - 28,826,980 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 8 29,105,676 - 29,155,434 (-) NCBI UU_Cfam_GSD_1.0
Ero1a Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024408640 76,380,350 - 76,425,758 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936697 2,154,065 - 2,199,926 (+) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936697 2,154,517 - 2,199,913 (+) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
ERO1A Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 1 182,265,261 - 182,318,195 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 1 182,268,651 - 182,318,147 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 1 202,436,374 - 202,588,694 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
ERO1A Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 24 29,708,521 - 29,777,939 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 24 29,717,710 - 29,777,918 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666053 17,992,077 - 18,051,108 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ero1a
.
Predicted Target Of
Count of predictions: 364 Count of miRNA genes: 226 Interacting mature miRNAs: 277 Transcripts: ENSRNOT00000009404 Prediction methods: Miranda, Targetscan Result types: miRGate_prediction
1641913 Colcr2 Colorectal carcinoma resistance QTL 2 6.57 0.0197 intestine integrity trait (VT:0010554) poorly differentiated malignant colorectal tumor number (CMO:0002076) 15 2266368 22711984 Rat 631273 Lecl2 Lens clarity QTL 2 0.001 lens clarity trait (VT:0001304) age of onset/diagnosis of cataract (CMO:0001584) 15 10596089 55596089 Rat 2300167 Bmd63 Bone mineral density QTL 63 5.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 15 11111142 56111142 Rat 1331729 Rf42 Renal function QTL 42 3.071 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 15 17362897 73690657 Rat 1641887 Alcrsp14 Alcohol response QTL 14 response to alcohol trait (VT:0010489) brain neurotensin receptor 1 density (CMO:0002068) 15 1 42356671 Rat 731170 Pur3 Proteinuria QTL 3 2.3 0.0005 urine protein amount (VT:0005160) urine protein excretion rate (CMO:0000759) 15 1 41686771 Rat 738017 Hcas7 Hepatocarcinoma susceptibility QTL 7 2.91 liver integrity trait (VT:0010547) liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464) 15 2266368 46921453 Rat 2300173 Bmd62 Bone mineral density QTL 62 12.8 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 15 11111142 56111142 Rat 9589149 Insul29 Insulin level QTL 29 9.06 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 15 1 34723002 Rat 61424 Scl1 Serum cholesterol level QTL 1 7.7 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 15 16725528 80672115 Rat 10401805 Kidm51 Kidney mass QTL 51 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 15 306329 45306329 Rat 1582251 Gluco24 Glucose level QTL 24 3.2 0.0008 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 15 5530756 50530756 Rat 1354657 Despr13 Despair related QTL 13 0.0022 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 15 1 29912054 Rat 2317750 Glom26 Glomerulus QTL 26 4.3 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 15 12496141 65205939 Rat 2298549 Neuinf12 Neuroinflammation QTL 12 3.5 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 15 1 55302115 Rat 8552920 Pigfal8 Plasma insulin-like growth factor 1 level QTL 8 3 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 15 1 34723002 Rat 2293688 Bss29 Bone structure and strength QTL 29 5.31 0.0001 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 15 11111142 56111142 Rat 5685002 Bss103 Bone structure and strength QTL 103 2.8 tibia strength trait (VT:1000284) tibia total energy absorbed before break (CMO:0001736) 15 14481165 28469888 Rat 8694361 Abfw6 Abdominal fat weight QTL 6 10.2 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 15 1 34723002 Rat
RH143391
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 18,530,310 - 18,530,410 (+) MAPPER mRatBN7.2 Rnor_6.0 15 19,655,252 - 19,655,351 NCBI Rnor6.0 Rnor_5.0 15 23,620,226 - 23,620,325 UniSTS Rnor5.0 RGSC_v3.4 15 21,205,407 - 21,205,506 UniSTS RGSC3.4 Celera 15 18,958,560 - 18,958,659 UniSTS RH 3.4 Map 15 145.2 UniSTS Cytogenetic Map 15 p14 UniSTS
AI599520
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 18,493,244 - 18,493,392 (+) MAPPER mRatBN7.2 Rnor_6.0 15 19,618,155 - 19,618,302 NCBI Rnor6.0 Rnor_5.0 15 23,583,376 - 23,583,523 UniSTS Rnor5.0 RGSC_v3.4 15 21,167,646 - 21,167,793 UniSTS RGSC3.4 Celera 15 18,921,532 - 18,921,679 UniSTS RH 3.4 Map 15 149.6 UniSTS Cytogenetic Map 15 p14 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000009404 ⟹ ENSRNOP00000009404
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 15 18,495,838 - 18,530,477 (-) Ensembl Rnor_6.0 Ensembl 15 19,619,973 - 19,655,381 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000100831 ⟹ ENSRNOP00000094942
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 15 18,492,946 - 18,530,478 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000116811 ⟹ ENSRNOP00000094430
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 15 18,492,945 - 18,530,447 (-) Ensembl
RefSeq Acc Id:
NM_138528 ⟹ NP_612537
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 15 20,974,771 - 21,010,170 (-) NCBI mRatBN7.2 15 18,495,037 - 18,530,440 (-) NCBI Rnor_6.0 15 19,619,947 - 19,655,381 (-) NCBI Rnor_5.0 15 23,585,168 - 23,620,355 (-) NCBI RGSC_v3.4 15 21,169,438 - 21,205,536 (-) RGD Celera 15 18,923,324 - 18,958,689 (-) RGD
Sequence:
GCGGCGAGCGGCGATGGGCCGCGCCTGGGGCTTGCTCGTCGGACTCTTGGGCGTCGTGTGGCTGCTGCGCTTGGGCCACGGCGAGGAGCGGCGGCCGGAGACAGCGGCACAGCGGTGTTTCTGTCAGG
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RefSeq Acc Id:
NP_612537 ⟸ NM_138528
- Peptide Label:
precursor
- UniProtKB:
Q8VH30 (UniProtKB/Swiss-Prot), Q8VH29 (UniProtKB/Swiss-Prot), Q8R4A1 (UniProtKB/Swiss-Prot), A0A8I6B1Q4 (UniProtKB/TrEMBL)
- Sequence:
MGRAWGLLVGLLGVVWLLRLGHGEERRPETAAQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLRKPCPFWNDINQCGRRDCAVKPCHSDEVPDGIKSASYKYSKEANLLE
hide sequence
Ensembl Acc Id:
ENSRNOP00000009404 ⟸ ENSRNOT00000009404
Ensembl Acc Id:
ENSRNOP00000094942 ⟸ ENSRNOT00000100831
Ensembl Acc Id:
ENSRNOP00000094430 ⟸ ENSRNOT00000116811
RGD ID: 13699595 Promoter ID: EPDNEW_R10118 Type: multiple initiation site Name: Ero1a_1 Description: endoplasmic reticulum oxidoreductase 1 alpha SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 15 19,655,416 - 19,655,476 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2016-07-07
Ero1a
endoplasmic reticulum oxidoreductase 1 alpha
Ero1a
endoplasmic reticulum oxidoreductase alpha
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2015-06-24
Ero1a
endoplasmic reticulum oxidoreductase alpha
Ero1l
ERO1-like (S. cerevisiae)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-02-23
Ero1l
ERO1-like (S. cerevisiae)
Ero1l_predicted
ERO1-like (S. cerevisiae) (predicted)
Data merged from RGD:1308220
737654 APPROVED
2005-01-20
Ero1l
ERO1-like (S. cerevisiae)
Symbol and Name status set to approved
1299863 APPROVED
2005-01-12
Ero1l_predicted
ERO1-like (S. cerevisiae) (predicted)
Symbol and Name status set to provisional
70820 PROVISIONAL
2002-08-07
Ero1l
ERO1-like (S. cerevisiae)
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_homology
homologous to ischemia-inducible gene 11(Giig11)
632668
gene_process
involved in oxidative endoplasmic reticulum protein folding
632668
