Symbol:
Ip6k2
Name:
inositol hexakisphosphate kinase 2
RGD ID:
620529
Description:
Predicted to enable flavonoid binding activity and inositol hexakisphosphate 5-kinase activity. Involved in phosphate ion transport. Predicted to be located in cell junction; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human IP6K2 (inositol hexakisphosphate kinase 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Ihpk2; inositol hexaphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; Pius
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 118,362,154 - 118,388,668 (+) NCBI GRCr8 mRatBN7.2 8 109,483,843 - 109,510,172 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 109,484,310 - 109,510,166 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 115,103,519 - 115,127,769 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 113,302,698 - 113,326,948 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 111,145,495 - 111,169,746 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 117,574,136 - 117,599,849 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 117,574,161 - 117,599,848 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 116,921,132 - 116,944,750 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 113,836,756 - 113,861,895 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 8 113,870,909 - 113,881,351 (+) NCBI Celera 8 108,780,684 - 108,804,293 (+) NCBI Celera Cytogenetic Map 8 q32 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Ip6k2 Rat (+)-catechin multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of IP6K2 mRNA CTD PMID:24763279 Ip6k2 Rat (-)-epigallocatechin 3-gallate multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of IP6K2 mRNA CTD PMID:22079256 Ip6k2 Rat 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression ISO Ip6k2 (Mus musculus) 6480464 2 more ... CTD PMID:25575267 Ip6k2 Rat 1,2-dimethylhydrazine decreases expression ISO Ip6k2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of IP6K2 mRNA CTD PMID:22206623 Ip6k2 Rat 1,2-dimethylhydrazine multiple interactions ISO Ip6k2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IP6K2 mRNA CTD PMID:22206623 Ip6k2 Rat 17beta-estradiol decreases expression ISO IP6K2 (Homo sapiens) 6480464 Estradiol results in decreased expression of IP6K2 mRNA CTD PMID:23019147 and PMID:31614463 Ip6k2 Rat 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of IP6K2 mRNA CTD PMID:32145629 Ip6k2 Rat 17beta-estradiol decreases expression ISO Ip6k2 (Mus musculus) 6480464 Estradiol results in decreased expression of IP6K2 mRNA CTD PMID:25575267 and PMID:39298647 Ip6k2 Rat 17beta-estradiol affects expression ISO IP6K2 (Homo sapiens) 6480464 Estradiol affects the expression of IP6K2 mRNA CTD PMID:22574217 Ip6k2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IP6K2 mRNA CTD PMID:21215274 and PMID:33387578 Ip6k2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IP6K2 mRNA CTD PMID:32109520 Ip6k2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO IP6K2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of IP6K2 mRNA CTD PMID:22574217 Ip6k2 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of IP6K2 mRNA CTD PMID:21346803 Ip6k2 Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of IP6K2 mRNA CTD PMID:21346803 Ip6k2 Rat 2-methylcholine affects expression ISO IP6K2 (Homo sapiens) 6480464 beta-methylcholine affects the expression of IP6K2 mRNA CTD PMID:21179406 Ip6k2 Rat 4,4'-sulfonyldiphenol decreases expression ISO Ip6k2 (Mus musculus) 6480464 bisphenol S results in decreased expression of IP6K2 mRNA CTD PMID:39298647 Ip6k2 Rat 4,4'-sulfonyldiphenol increases methylation ISO IP6K2 (Homo sapiens) 6480464 bisphenol S results in increased methylation of IP6K2 gene CTD PMID:31601247 Ip6k2 Rat 4-hydroxyphenyl retinamide increases expression ISO Ip6k2 (Mus musculus) 6480464 Fenretinide results in increased expression of IP6K2 mRNA CTD PMID:28973697 Ip6k2 Rat 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of IP6K2 mRNA CTD PMID:25825206 Ip6k2 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of IP6K2 mRNA CTD PMID:30047161 Ip6k2 Rat acrylamide increases expression ISO IP6K2 (Homo sapiens) 6480464 Acrylamide results in increased expression of IP6K2 mRNA CTD PMID:32763439 Ip6k2 Rat aflatoxin B1 decreases methylation ISO IP6K2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of IP6K2 gene CTD PMID:27153756 Ip6k2 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of IP6K2 mRNA CTD PMID:30047161 Ip6k2 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IP6K2 mRNA CTD PMID:16483693 Ip6k2 Rat antirheumatic drug increases expression ISO IP6K2 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of IP6K2 mRNA CTD PMID:24449571 Ip6k2 Rat aristolochic acid A increases expression ISO IP6K2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of IP6K2 mRNA CTD PMID:33212167 Ip6k2 Rat arsane affects methylation ISO IP6K2 (Homo sapiens) 6480464 Arsenic affects the methylation of IP6K2 gene CTD PMID:25304211 Ip6k2 Rat arsane increases expression ISO IP6K2 (Homo sapiens) 6480464 Arsenic results in increased expression of IP6K2 mRNA CTD PMID:31739468 Ip6k2 Rat arsane multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in increased expression of IP6K2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of IP6K2 mRNA CTD PMID:31739468 and PMID:39836092 Ip6k2 Rat arsenic atom affects methylation ISO IP6K2 (Homo sapiens) 6480464 Arsenic affects the methylation of IP6K2 gene CTD PMID:25304211 Ip6k2 Rat arsenic atom multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in increased expression of IP6K2 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of IP6K2 mRNA CTD PMID:31739468 and PMID:39836092 Ip6k2 Rat arsenic atom increases expression ISO IP6K2 (Homo sapiens) 6480464 Arsenic results in increased expression of IP6K2 mRNA CTD PMID:31739468 Ip6k2 Rat benzo[a]pyrene decreases expression ISO Ip6k2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of IP6K2 mRNA CTD PMID:19770486 Ip6k2 Rat benzo[a]pyrene diol epoxide I increases expression ISO IP6K2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 Ip6k2 Rat beta-lapachone increases expression ISO IP6K2 (Homo sapiens) 6480464 beta-lapachone results in increased expression of IP6K2 mRNA CTD PMID:38218311 Ip6k2 Rat bisphenol A decreases expression ISO Ip6k2 (Mus musculus) 6480464 bisphenol A results in decreased expression of IP6K2 mRNA CTD PMID:25575267 Ip6k2 Rat bisphenol A increases expression ISO Ip6k2 (Mus musculus) 6480464 bisphenol A results in increased expression of IP6K2 mRNA CTD PMID:33221593 Ip6k2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of IP6K2 mRNA CTD PMID:32145629 Ip6k2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IP6K2 mRNA CTD PMID:30816183 more ... Ip6k2 Rat bisphenol A affects expression ISO IP6K2 (Homo sapiens) 6480464 bisphenol A affects the expression of IP6K2 mRNA CTD PMID:30903817 Ip6k2 Rat bisphenol A decreases methylation ISO Ip6k2 (Mus musculus) 6480464 bisphenol A results in decreased methylation of IP6K2 promoter CTD PMID:27312807 Ip6k2 Rat bromobenzene affects expression EXP 6480464 bromobenzene affects the expression of IP6K2 mRNA CTD PMID:32479839 Ip6k2 Rat cadmium dichloride decreases expression ISO IP6K2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of IP6K2 mRNA CTD PMID:38568856 Ip6k2 Rat chlorpyrifos increases expression ISO Ip6k2 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of IP6K2 mRNA CTD PMID:37019170 Ip6k2 Rat ciguatoxin CTX1B affects expression ISO Ip6k2 (Mus musculus) 6480464 Ciguatoxins affects the expression of IP6K2 mRNA CTD PMID:18353800 Ip6k2 Rat clotrimazole decreases expression EXP 6480464 Clotrimazole results in decreased expression of IP6K2 mRNA CTD PMID:30047161 Ip6k2 Rat cobalt dichloride increases expression ISO IP6K2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of IP6K2 mRNA CTD PMID:19320972 Ip6k2 Rat copper(II) sulfate increases expression ISO IP6K2 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of IP6K2 mRNA CTD PMID:19549813 Ip6k2 Rat coumestrol multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IP6K2 mRNA CTD PMID:19167446 Ip6k2 Rat coumestrol decreases expression ISO IP6K2 (Homo sapiens) 6480464 Coumestrol results in decreased expression of IP6K2 mRNA CTD PMID:19167446 Ip6k2 Rat crocidolite asbestos decreases expression ISO Ip6k2 (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of IP6K2 mRNA CTD PMID:29279043 Ip6k2 Rat cyclosporin A decreases expression ISO IP6K2 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of IP6K2 mRNA CTD PMID:27989131 Ip6k2 Rat DDE decreases expression ISO IP6K2 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of IP6K2 mRNA CTD PMID:38568856 Ip6k2 Rat Dibutyl phosphate affects expression ISO IP6K2 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of IP6K2 mRNA CTD PMID:37042841 Ip6k2 Rat dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of IP6K2 mRNA CTD PMID:21266533 Ip6k2 Rat diethylstilbestrol decreases expression ISO Ip6k2 (Mus musculus) 6480464 Diethylstilbestrol results in decreased expression of IP6K2 mRNA CTD PMID:25575267 Ip6k2 Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of IP6K2 mRNA CTD PMID:29391264 Ip6k2 Rat endosulfan affects expression EXP 6480464 Endosulfan affects the expression of IP6K2 mRNA CTD PMID:31464424 Ip6k2 Rat Enterolactone multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of IP6K2 mRNA CTD PMID:19167446 Ip6k2 Rat erythromycin estolate decreases expression EXP 6480464 Erythromycin Estolate results in decreased expression of IP6K2 mRNA CTD PMID:24412560 Ip6k2 Rat estriol decreases expression ISO Ip6k2 (Mus musculus) 6480464 Estriol results in decreased expression of IP6K2 mRNA CTD PMID:25575267 Ip6k2 Rat ethanol affects splicing ISO Ip6k2 (Mus musculus) 6480464 Ethanol affects the splicing of IP6K2 mRNA CTD PMID:30319688 Ip6k2 Rat ethyl methanesulfonate increases expression ISO IP6K2 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of IP6K2 mRNA CTD PMID:23649840 Ip6k2 Rat fenthion increases expression ISO Ip6k2 (Mus musculus) 6480464 Fenthion results in increased expression of IP6K2 mRNA CTD PMID:34813904 Ip6k2 Rat folic acid multiple interactions ISO Ip6k2 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IP6K2 mRNA CTD PMID:22206623 Ip6k2 Rat formaldehyde increases expression ISO IP6K2 (Homo sapiens) 6480464 Formaldehyde results in increased expression of IP6K2 mRNA CTD PMID:23649840 Ip6k2 Rat gallic acid increases expression ISO IP6K2 (Homo sapiens) 6480464 Gallic Acid results in increased expression of IP6K2 mRNA CTD PMID:34408198 Ip6k2 Rat iron atom multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in increased expression of IP6K2 mRNA CTD PMID:31739468 Ip6k2 Rat iron(0) multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [Arsenic co-treated with Iron] results in increased expression of IP6K2 mRNA CTD PMID:31739468 Ip6k2 Rat leflunomide increases expression EXP 6480464 leflunomide results in increased expression of IP6K2 mRNA CTD PMID:24136188 Ip6k2 Rat levofloxacin increases expression EXP 6480464 Levofloxacin results in increased expression of IP6K2 mRNA CTD PMID:24136188 Ip6k2 Rat methidathion increases expression ISO Ip6k2 (Mus musculus) 6480464 methidathion results in increased expression of IP6K2 mRNA CTD PMID:34813904 Ip6k2 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of IP6K2 mRNA CTD PMID:30047161 Ip6k2 Rat methyl methanesulfonate increases expression ISO IP6K2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of IP6K2 mRNA CTD PMID:23649840 Ip6k2 Rat Methylazoxymethanol acetate decreases expression EXP 6480464 Methylazoxymethanol Acetate results in decreased expression of IP6K2 mRNA CTD PMID:28349193 Ip6k2 Rat N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of IP6K2 mRNA CTD PMID:20360939 Ip6k2 Rat N-nitrosodiethylamine multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of IP6K2 mRNA] CTD PMID:20360939 Ip6k2 Rat orphenadrine affects expression EXP 6480464 Orphenadrine affects the expression of IP6K2 mRNA CTD PMID:23665939 Ip6k2 Rat oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of IP6K2 mRNA CTD PMID:23439660 Ip6k2 Rat paracetamol affects expression ISO Ip6k2 (Mus musculus) 6480464 Acetaminophen affects the expression of IP6K2 mRNA CTD PMID:17562736 Ip6k2 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of IP6K2 mRNA CTD PMID:33387578 Ip6k2 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Ip6k2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of IP6K2 mRNA CTD PMID:36331819 Ip6k2 Rat phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of IP6K2 mRNA] CTD PMID:20360939 Ip6k2 Rat phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of IP6K2 mRNA CTD PMID:31324951 Ip6k2 Rat phenobarbital affects expression ISO Ip6k2 (Mus musculus) 6480464 Phenobarbital affects the expression of IP6K2 mRNA CTD PMID:23091169 Ip6k2 Rat pirinixic acid increases expression ISO Ip6k2 (Mus musculus) 6480464 pirinixic acid results in increased expression of IP6K2 mRNA CTD PMID:18301758 and PMID:23811191 Ip6k2 Rat potassium chromate increases expression ISO IP6K2 (Homo sapiens) 6480464 potassium chromate(VI) results in increased expression of IP6K2 mRNA CTD PMID:22079256 Ip6k2 Rat potassium chromate multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of IP6K2 mRNA CTD PMID:22079256 Ip6k2 Rat pregnenolone 16alpha-carbonitrile increases expression ISO Ip6k2 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of IP6K2 mRNA CTD PMID:28903501 Ip6k2 Rat quercetin increases expression ISO IP6K2 (Homo sapiens) 6480464 Quercetin results in increased expression of IP6K2 mRNA CTD PMID:21632981 Ip6k2 Rat ritodrine increases expression ISO Ip6k2 (Mus musculus) 6480464 Ritodrine results in increased expression of IP6K2 mRNA CTD PMID:23370008 Ip6k2 Rat silicon dioxide increases expression ISO IP6K2 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of IP6K2 mRNA CTD PMID:25351596 Ip6k2 Rat silver atom increases expression ISO IP6K2 (Homo sapiens) 6480464 Silver results in increased expression of IP6K2 mRNA CTD PMID:26014281 Ip6k2 Rat silver(0) increases expression ISO IP6K2 (Homo sapiens) 6480464 Silver results in increased expression of IP6K2 mRNA CTD PMID:26014281 Ip6k2 Rat sodium arsenite multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of IP6K2 mRNA CTD PMID:39836092 Ip6k2 Rat Soman increases expression EXP 6480464 Soman results in increased expression of IP6K2 mRNA CTD PMID:19281266 Ip6k2 Rat sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of IP6K2 mRNA CTD PMID:30047161 Ip6k2 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of IP6K2 mRNA CTD PMID:31150632 Ip6k2 Rat tetrachloromethane increases expression ISO Ip6k2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of IP6K2 mRNA CTD PMID:31919559 Ip6k2 Rat triphenyl phosphate affects expression ISO IP6K2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of IP6K2 mRNA CTD PMID:37042841 Ip6k2 Rat triptonide decreases expression ISO Ip6k2 (Mus musculus) 6480464 triptonide results in decreased expression of IP6K2 mRNA CTD PMID:33045310 Ip6k2 Rat troglitazone decreases expression ISO Ip6k2 (Mus musculus) 6480464 troglitazone results in decreased expression of IP6K2 mRNA CTD PMID:28973697 Ip6k2 Rat trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of IP6K2 mRNA CTD PMID:24136188 Ip6k2 Rat urethane increases expression ISO IP6K2 (Homo sapiens) 6480464 Urethane results in increased expression of IP6K2 mRNA CTD PMID:28818685 Ip6k2 Rat valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of IP6K2 mRNA CTD PMID:24136188 Ip6k2 Rat valproic acid decreases expression ISO IP6K2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of IP6K2 mRNA CTD PMID:23179753 and PMID:28001369 Ip6k2 Rat valproic acid affects expression ISO IP6K2 (Homo sapiens) 6480464 Valproic Acid affects the expression of IP6K2 mRNA CTD PMID:25979313 Ip6k2 Rat valproic acid decreases methylation ISO IP6K2 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of IP6K2 gene CTD PMID:29154799 Ip6k2 Rat vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of IP6K2 mRNA CTD PMID:23034163 Ip6k2 Rat zinc atom multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of IP6K2 mRNA CTD PMID:18593933 Ip6k2 Rat zinc(0) multiple interactions ISO IP6K2 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of IP6K2 mRNA CTD PMID:18593933
(+)-catechin (ISO) (-)-epigallocatechin 3-gallate (ISO) 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane (ISO) 1,2-dimethylhydrazine (ISO) 17beta-estradiol (EXP,ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,4-dinitrotoluene (EXP) 2,6-dinitrotoluene (EXP) 2-methylcholine (ISO) 4,4'-sulfonyldiphenol (ISO) 4-hydroxyphenyl retinamide (ISO) 6-propyl-2-thiouracil (EXP) acrylamide (ISO) aflatoxin B1 (ISO) amitrole (EXP) ammonium chloride (EXP) antirheumatic drug (ISO) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) beta-lapachone (ISO) bisphenol A (EXP,ISO) bromobenzene (EXP) cadmium dichloride (ISO) chlorpyrifos (ISO) ciguatoxin CTX1B (ISO) clotrimazole (EXP) cobalt dichloride (ISO) copper(II) sulfate (ISO) coumestrol (ISO) crocidolite asbestos (ISO) cyclosporin A (ISO) DDE (ISO) Dibutyl phosphate (ISO) dibutyl phthalate (EXP) diethylstilbestrol (ISO) endosulfan (EXP) Enterolactone (ISO) erythromycin estolate (EXP) estriol (ISO) ethanol (ISO) ethyl methanesulfonate (ISO) fenthion (ISO) folic acid (ISO) formaldehyde (ISO) gallic acid (ISO) iron atom (ISO) iron(0) (ISO) leflunomide (EXP) levofloxacin (EXP) methidathion (ISO) methimazole (EXP) methyl methanesulfonate (ISO) Methylazoxymethanol acetate (EXP) N-nitrosodiethylamine (EXP) orphenadrine (EXP) oxycodone (EXP) paracetamol (EXP,ISO) perfluorooctane-1-sulfonic acid (ISO) phenethyl caffeate (EXP) phenformin (EXP) phenobarbital (ISO) pirinixic acid (ISO) potassium chromate (ISO) pregnenolone 16alpha-carbonitrile (ISO) quercetin (ISO) ritodrine (ISO) silicon dioxide (ISO) silver atom (ISO) silver(0) (ISO) sodium arsenite (ISO) Soman (EXP) sulfadimethoxine (EXP) tetrachloromethane (EXP,ISO) triphenyl phosphate (ISO) triptonide (ISO) troglitazone (ISO) trovafloxacin (EXP) urethane (ISO) valdecoxib (EXP) valproic acid (ISO) vinclozolin (EXP) zinc atom (ISO) zinc(0) (ISO)
Biological Process
cellular response to flavonoid (IEA,ISO,ISS) inositol phosphate biosynthetic process (IBA,IEA,ISO) inositol phosphate metabolic process (IEA,ISO,ISS) lipid metabolic process (IEA) negative regulation of cell growth (IEA,ISO) phosphate ion transport (IDA) phosphatidylinositol metabolic process (IEA) phosphatidylinositol phosphate biosynthetic process (IBA,IEA,ISO) positive regulation of apoptotic process (IEA,ISO) positive regulation of peptidyl-serine phosphorylation (ISO) protein stabilization (IEA,ISO)
Ip6k2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 8 118,362,154 - 118,388,668 (+) NCBI GRCr8 mRatBN7.2 8 109,483,843 - 109,510,172 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 8 109,484,310 - 109,510,166 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 8 115,103,519 - 115,127,769 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 8 113,302,698 - 113,326,948 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 8 111,145,495 - 111,169,746 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 8 117,574,136 - 117,599,849 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 8 117,574,161 - 117,599,848 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 8 116,921,132 - 116,944,750 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 8 113,836,756 - 113,861,895 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 8 113,870,909 - 113,881,351 (+) NCBI Celera 8 108,780,684 - 108,804,293 (+) NCBI Celera Cytogenetic Map 8 q32 NCBI
IP6K2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 3 48,688,003 - 48,717,221 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 3 48,688,003 - 48,740,353 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 3 48,725,436 - 48,754,654 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 3 48,700,440 - 48,729,710 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 3 48,700,440 - 48,729,710 NCBI Celera 3 48,681,373 - 48,710,646 (-) NCBI Celera Cytogenetic Map 3 p21.31 NCBI HuRef 3 48,783,857 - 48,813,325 (-) NCBI HuRef CHM1_1 3 48,677,527 - 48,706,810 (-) NCBI CHM1_1 T2T-CHM13v2.0 3 48,716,988 - 48,746,201 (-) NCBI T2T-CHM13v2.0
Ip6k2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 9 108,660,928 - 108,683,532 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 9 108,660,995 - 108,683,536 (+) Ensembl GRCm39 Ensembl GRCm38 9 108,783,764 - 108,806,333 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 9 108,783,796 - 108,806,337 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 9 108,698,325 - 108,708,664 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 9 108,653,217 - 108,663,556 (+) NCBI MGSCv36 mm8 Celera 9 108,403,128 - 108,413,468 (+) NCBI Celera Cytogenetic Map 9 F2 NCBI cM Map 9 59.63 NCBI
Ip6k2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955532 766,577 - 794,409 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955532 766,577 - 794,461 (-) NCBI ChiLan1.0 ChiLan1.0
IP6K2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 2 48,662,753 - 48,693,498 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 3 48,667,521 - 48,698,266 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 3 48,608,902 - 48,638,185 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 3 49,690,486 - 49,719,811 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 3 49,690,486 - 49,719,798 (-) Ensembl panpan1.1 panPan2
IP6K2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 20 40,403,260 - 40,437,863 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 20 40,427,083 - 40,437,804 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 20 40,320,579 - 40,355,092 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 20 40,888,751 - 40,923,377 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 20 40,888,832 - 40,923,377 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 20 40,126,293 - 40,160,881 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 20 40,530,369 - 40,565,188 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 20 40,812,078 - 40,846,684 (+) NCBI UU_Cfam_GSD_1.0
Ip6k2
IP6K2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 13 31,379,521 - 31,406,911 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 13 31,379,516 - 31,406,989 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 13 34,646,759 - 34,655,148 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
IP6K2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 22 10,097,730 - 10,121,325 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 22 10,097,746 - 10,121,840 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666041 156,967,477 - 156,992,136 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Ip6k2
.
Predicted Target Of
Count of predictions: 56 Count of miRNA genes: 47 Interacting mature miRNAs: 56 Transcripts: ENSRNOT00000027584 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2303171 Bp331 Blood pressure QTL 331 5.57 0.005 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 61290298 119084929 Rat 1549909 Stresp11 Stress response QTL 11 6.83 0.0019 stress-related behavior trait (VT:0010451) number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960) 8 73473045 118473045 Rat 631210 Bw3 Body weight QTL3 5.9 mesenteric fat pad mass (VT:0010427) mesenteric fat pad weight to body weight ratio (CMO:0000654) 8 69349194 112783834 Rat 1358903 Bp252 Blood pressure QTL 252 7 0.0001 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 93965141 123900184 Rat 1554321 Bmd3 Bone mineral density QTL 3 7.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 40952565 123900184 Rat 9590292 Uminl3 Urine mineral level QTL 3 3.62 0.001 urine mineral amount (VT:0015086) urine electrolyte level (CMO:0000593) 8 71888757 116888757 Rat 8694446 Bw170 Body weight QTL 170 12.07 0.001 retroperitoneal fat pad mass (VT:0010430) retroperitoneal fat pad weight to body weight ratio (CMO:0000635) 8 71888757 116888757 Rat 631650 Stl6 Serum triglyceride level QTL 6 4 0.0019 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 8 10378157 112202585 Rat 631653 Bp125 Blood pressure QTL 125 3.3 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 66142385 111142385 Rat 1581557 Eae16 Experimental allergic encephalomyelitis QTL 16 3.8 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046) 8 8462195 110921472 Rat 738011 Anxrr9 Anxiety related response QTL 9 6.1 exploratory behavior trait (VT:0010471) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 8 93535351 123900184 Rat 724539 Cm19 Cardiac mass QTL 19 2.6 heart mass (VT:0007028) calculated heart weight (CMO:0000073) 8 100149864 120994388 Rat 70197 BpQTLcluster8 Blood pressure QTL cluster 8 3.482 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 8 46531639 119088626 Rat 738014 Anxrr15 Anxiety related response QTL 15 3.6 0.005 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 8 95718998 123900184 Rat 2300182 Bmd56 Bone mineral density QTL 56 5.4 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 95718998 123900184 Rat 2300181 Bmd55 Bone mineral density QTL 55 5.7 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 8 76468691 121468691 Rat 1300171 Bp184 Blood pressure QTL 184 3.66 arterial blood pressure trait (VT:2000000) blood pressure time series experimental set point of the baroreceptor response (CMO:0002593) 8 70513503 118219066 Rat 1358893 Bp263 Blood pressure QTL 263 5.01 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 8 93965141 123900184 Rat 2313400 Anxrr25 Anxiety related response QTL 25 aggression-related behavior trait (VT:0015014) tameness/aggressiveness composite score (CMO:0002136) 8 89265192 114019816 Rat 8694200 Abfw4 Abdominal fat weight QTL 4 9.07 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 8 71888757 116888757 Rat 8694392 Bw161 Body weight QTL 161 8.06 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 8 71888757 116888757 Rat 61437 Cia6 Collagen induced arthritis QTL 6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 8 82460758 122812818 Rat
RH144690
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 8 109,497,031 - 109,497,247 (+) MAPPER mRatBN7.2 Rnor_6.0 8 117,586,900 - 117,587,115 NCBI Rnor6.0 Rnor_5.0 8 116,932,067 - 116,932,282 UniSTS Rnor5.0 RGSC_v3.4 8 113,848,833 - 113,849,048 UniSTS RGSC3.4 Celera 8 108,791,530 - 108,791,745 UniSTS RH 3.4 Map 8 1115.3 UniSTS Cytogenetic Map 8 q32 UniSTS
UniSTS:532317
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 8 109,509,564 - 109,509,986 (+) MAPPER mRatBN7.2 Rnor_6.0 8 117,599,243 - 117,599,664 NCBI Rnor6.0 Rnor_5.0 8 116,944,144 - 116,944,565 UniSTS Rnor5.0 Celera 8 108,803,687 - 108,804,108 UniSTS Cytogenetic Map 8 q32 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000027584 ⟹ ENSRNOP00000027584
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 109,499,531 - 109,510,166 (+) Ensembl Rnor_6.0 Ensembl 8 117,576,788 - 117,599,848 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000077078 ⟹ ENSRNOP00000071056
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 109,484,310 - 109,510,166 (+) Ensembl Rnor_6.0 Ensembl 8 117,574,161 - 117,599,843 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000099109 ⟹ ENSRNOP00000092455
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 8 109,499,531 - 109,500,567 (+) Ensembl
RefSeq Acc Id:
NM_021660 ⟹ NP_067692
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,364,677 - 118,388,668 (+) NCBI mRatBN7.2 8 109,486,179 - 109,510,172 (+) NCBI Rnor_6.0 8 117,576,048 - 117,599,849 (+) NCBI Rnor_5.0 8 116,921,132 - 116,944,750 (+) NCBI RGSC_v3.4 8 113,836,756 - 113,861,895 (+) RGD Celera 8 108,780,684 - 108,804,293 (+) RGD
Sequence:
CCTGCCTCTGATGTGCCAGGATTAGAGAGTGCTGAAGACAAGAAGTTTTGGAGTTGTGAGTGAATCCCGGTACTCAAAAATGAGGCTACTTCCAAACCTCATGTCATTGTGTTTGCTTCCGCCAGTGT
hide sequence
RefSeq Acc Id:
XM_008766564 ⟹ XP_008764786
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,362,645 - 118,388,668 (+) NCBI mRatBN7.2 8 109,484,212 - 109,510,172 (+) NCBI Rnor_6.0 8 117,574,137 - 117,599,849 (+) NCBI
Sequence:
CGGGAGCGAGGCTGGGGGGCGGGGCCGAGCCCGGCCGCAGCCATTTTGGTGGAAGAGAAACAATAGGACGGAAGCGTCGCGGGACTGGGCTGTGGCCGCAGTGTGTGCTGGCCTGCACAGACCGAGGA
hide sequence
RefSeq Acc Id:
XM_039082043 ⟹ XP_038937971
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,364,824 - 118,388,668 (+) NCBI mRatBN7.2 8 109,486,926 - 109,510,172 (+) NCBI
RefSeq Acc Id:
XM_039082044 ⟹ XP_038937972
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,362,450 - 118,379,799 (+) NCBI mRatBN7.2 8 109,483,843 - 109,501,302 (+) NCBI
RefSeq Acc Id:
XM_039082045 ⟹ XP_038937973
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,362,154 - 118,379,799 (+) NCBI mRatBN7.2 8 109,483,847 - 109,501,302 (+) NCBI
RefSeq Acc Id:
XM_063266056 ⟹ XP_063122126
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,363,096 - 118,388,668 (+) NCBI
RefSeq Acc Id:
XM_063266057 ⟹ XP_063122127
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,362,710 - 118,388,668 (+) NCBI
RefSeq Acc Id:
XM_063266058 ⟹ XP_063122128
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 8 118,378,110 - 118,388,668 (+) NCBI
RefSeq Acc Id:
NP_067692 ⟸ NM_021660
- UniProtKB:
Q5XIU6 (UniProtKB/Swiss-Prot), Q9R0U1 (UniProtKB/Swiss-Prot), A6I382 (UniProtKB/TrEMBL), A0A8L2UKG6 (UniProtKB/TrEMBL)
- Sequence:
MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTPQYKGVVSVRFEEDEDRNLCLIAYPLKGDHGPVDIVDNSDCEPKSKLLRWTNKKHHVLETEKSPK
hide sequence
RefSeq Acc Id:
XP_008764786 ⟸ XM_008766564
- Peptide Label:
isoform X1
- Sequence:
MSPAFRTMDVEPRTKGILLEPFVHQVGGHSCVLRFNETTLCKPLVPREHQFYETLPAEMRRFTP
hide sequence
Ensembl Acc Id:
ENSRNOP00000071056 ⟸ ENSRNOT00000077078
Ensembl Acc Id:
ENSRNOP00000027584 ⟸ ENSRNOT00000027584
RefSeq Acc Id:
XP_038937972 ⟸ XM_039082044
- Peptide Label:
isoform X2
RefSeq Acc Id:
XP_038937973 ⟸ XM_039082045
- Peptide Label:
isoform X4
- UniProtKB:
A6I383 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038937971 ⟸ XM_039082043
- Peptide Label:
isoform X1
- UniProtKB:
Q9R0U1 (UniProtKB/Swiss-Prot), Q5XIU6 (UniProtKB/Swiss-Prot), A6I382 (UniProtKB/TrEMBL), A0A8L2UKG6 (UniProtKB/TrEMBL)
Ensembl Acc Id:
ENSRNOP00000092455 ⟸ ENSRNOT00000099109
RefSeq Acc Id:
XP_063122127 ⟸ XM_063266057
- Peptide Label:
isoform X3
RefSeq Acc Id:
XP_063122126 ⟸ XM_063266056
- Peptide Label:
isoform X1
- UniProtKB:
Q9R0U1 (UniProtKB/Swiss-Prot), Q5XIU6 (UniProtKB/Swiss-Prot), A6I382 (UniProtKB/TrEMBL), A0A8L2UKG6 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063122128 ⟸ XM_063266058
- Peptide Label:
isoform X3
RGD ID: 13696324 Promoter ID: EPDNEW_R6840 Type: initiation region Name: Ip6k2_1 Description: inositol hexakisphosphate kinase 2 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 8 117,574,173 - 117,574,233 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2009-02-26
Ip6k2
inositol hexakisphosphate kinase 2
Ihpk2
inositol hexaphosphate kinase 2
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2004-09-10
Ihpk2
inositol hexaphosphate kinase 2
Pius
PiUS protein
Symbol and Name updated
1299863 APPROVED
2002-08-07
Pius
PiUS protein
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_protein
424 amino acids; 51 kDa
633655
