Rnase1 (ribonuclease A family member 1, pancreatic) - Rat Genome Database

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Gene: Rnase1 (ribonuclease A family member 1, pancreatic) Rattus norvegicus
Analyze
Symbol: Rnase1
Name: ribonuclease A family member 1, pancreatic
RGD ID: 3574
Description: Predicted to enable RNA nuclease activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytosol and lysosomal lumen. Orthologous to human RNASE1 (ribonuclease A family member 1, pancreatic); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103690354; pancreatic ribonuclease; Rib1; ribonuclease 1 pancreatic; ribonuclease 1, pancreatic; ribonuclease pancreatic beta-type; ribonuclease RNase A family 1; ribonuclease, RNase A family, 1; ribonuclease, RNase A family, 1 (pancreatic); RL1; RNase 1 gamma; RNase A
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,835,436 - 26,837,145 (-)NCBIGRCr8
mRatBN7.21524,361,924 - 24,363,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,361,927 - 24,363,624 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,133,082 - 27,134,791 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,092,239 - 28,093,948 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,341,641 - 26,343,350 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,073,963 - 28,075,677 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,074,953 - 28,075,411 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01531,897,124 - 31,898,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,123,440 - 27,124,991NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,139,139 - 27,140,691NCBI
Celera1524,679,524 - 24,681,067 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1RatCOVID-19  ISORNASE1 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1RatBrain-Lung-Thyroid Syndrome  ISORNASE1 (Homo sapiens)8554872ClinVar Annotator: match by term: Brain-lung-thyroid syndromeClinVarPMID:25741868
Rnase1Ratpurine nucleoside phosphorylase deficiency  ISORNASE1 (Homo sapiens)8554872ClinVar Annotator: match by term: Purine-nucleoside phosphorylase deficiencyClinVarPMID:24767876 and PMID:28492532

1 to 20 of 64 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1Rat1,2-dichloroethane increases expressionISORnase1 (Mus musculus)6480464ethylene dichloride results in increased expression of RNASE1 mRNACTDPMID:28960355
Rnase1Rat1,2-dimethylhydrazine affects expressionISORnase1 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of RNASE1 mRNACTDPMID:22206623
Rnase1Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of RNASE1 mRNACTDPMID:32145629
Rnase1Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of RNASE1 mRNACTDPMID:32741896
Rnase1Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of RNASE1 mRNACTDPMID:32741896
Rnase1Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISORNASE1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Rnase1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORnase1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RNASE1 mRNACTDPMID:26377647
Rnase1Rat2,4,6-tribromophenol decreases expressionISORNASE1 (Homo sapiens)64804642 more ...CTDPMID:31675489
Rnase1Rat2,4,6-trinitrobenzenesulfonic acid increases expressionISORnase1 (Mus musculus)6480464Trinitrobenzenesulfonic Acid results in increased expression of RNASE1 mRNACTDPMID:17982090
Rnase1Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISORNASE1 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of RNASE1 mRNA and tetrabromobisphenol A results in decreased expression of RNASE1 proteinCTDPMID:31675489 and PMID:33476716
Rnase1Rat3,4-methylenedioxymethamphetamine decreases expressionISORnase1 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RNASE1 mRNACTDPMID:20188158
Rnase1Rat3H-1,2-dithiole-3-thione increases expressionEXP 64804641 and 2-dithiol-3-thione results in increased expression of RNASE1 mRNACTDPMID:19162173
Rnase1Ratacetylsalicylic acid increases expressionISORNASE1 (Homo sapiens)6480464Aspirin results in increased expression of RNASE1 mRNACTDPMID:11906190
Rnase1Rataflatoxin B1 increases methylationISORNASE1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of RNASE1 geneCTDPMID:27153756
Rnase1Ratall-trans-retinoic acid decreases expressionISORnase1 (Mus musculus)6480464Tretinoin results in decreased expression of RNASE1 mRNACTDPMID:16604517
Rnase1Ratall-trans-retinoic acid increases expressionISORNASE1 (Homo sapiens)6480464Tretinoin results in increased expression of RNASE1 mRNACTDPMID:23830798
Rnase1Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RNASE1 mRNACTDPMID:16483693
Rnase1Ratatrazine increases expressionISORNASE1 (Homo sapiens)6480464Atrazine results in increased expression of RNASE1 mRNACTDPMID:22378314
Rnase1Ratbenzo[a]pyrene increases methylationISORNASE1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of RNASE1 exonCTDPMID:27901495
Rnase1Ratbenzo[a]pyrene decreases methylationISORNASE1 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of RNASE1 5' UTRCTDPMID:27901495

1 to 20 of 64 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1Ratdefense response to Gram-positive bacterium involved_inIBAMGI:1925666 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rnase1Ratdefense response to virus NOT|involved_inISORNASE1 (Homo sapiens)1624291 PMID:9826755RGDPMID:9826755
Rnase1Ratresponse to bacterium acts_upstream_of_or_withinISORnase1 (Mus musculus)1624291 PMID:23012479RGDPMID:23012479

Cellular Component
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9622851ReactomeReactome:R-RNO-9622851
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9624154ReactomeReactome:R-RNO-9624154
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9622832ReactomeReactome:R-RNO-9622832
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9625173ReactomeReactome:R-RNO-9625173
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9625183ReactomeReactome:R-RNO-9625183
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9615712ReactomeReactome:R-RNO-9615712
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9625160ReactomeReactome:R-RNO-9625160
Rnase1Ratcytosol located_inTAS 1600115Reactome:R-RNO-9620205ReactomeReactome:R-RNO-9620205
Rnase1Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Rnase1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Rnase1Ratlysosomal lumen located_inTAS 1600115Reactome:R-RNO-9625160ReactomeReactome:R-RNO-9625160
Rnase1Ratlysosomal lumen located_inTAS 1600115Reactome:R-RNO-9626028ReactomeReactome:R-RNO-9626028
1 to 12 of 12 rows

Molecular Function
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rnase1Ratendonuclease activity enablesIEAUniProtKB-KW:KW-02551600115GO_REF:0000043UniProtGO_REF:0000043
Rnase1Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Rnase1Ratlyase activity enablesIEAUniProtKB-KW:KW-04561600115GO_REF:0000043UniProtGO_REF:0000043
Rnase1Ratnuclease activity enablesIEAUniProtKB-KW:KW-05401600115GO_REF:0000043UniProtGO_REF:0000043
Rnase1Ratnucleic acid binding enablesIEAInterPro:IPR0014271600115GO_REF:0000002InterProGO_REF:0000002
Rnase1Ratprotein binding enablesISORNASE1 (Homo sapiens)1624291UniProtKB:P13489 more ...RGDPMID:17350650 more ...
Rnase1Ratribonuclease A activity enablesIEAEC:4.6.1.181600115GO_REF:0000003UniProtGO_REF:0000003
Rnase1RatRNA nuclease activity enablesISORNASE1 (Homo sapiens)1624291 PMID:9826755RGDPMID:9826755
Rnase1RatRNA nuclease activity enablesIBAMGI:104984 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 9 of 9 rows


#
Reference Title
Reference Citation
1. Pancreatic-type ribonuclease 1 gene duplications in rat species. Dubois JY, etal., J Mol Evol 2002 Nov;55(5):522-33.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat pancreatic ribonuclease messenger RNA. The nucleotide sequence of the entire mRNA and the derived amino acid sequence of the pre-enzyme. MacDonald RJ, etal., J Biol Chem 1982 Dec 25;257(24):14582-5.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:4710592   PMID:6873294   PMID:9826755   PMID:10090281   PMID:23376485   PMID:23533145  



Rnase1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,835,436 - 26,837,145 (-)NCBIGRCr8
mRatBN7.21524,361,924 - 24,363,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,361,927 - 24,363,624 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,133,082 - 27,134,791 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,092,239 - 28,093,948 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,341,641 - 26,343,350 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,073,963 - 28,075,677 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,074,953 - 28,075,411 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01531,897,124 - 31,898,675 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,123,440 - 27,124,991NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,139,139 - 27,140,691NCBI
Celera1524,679,524 - 24,681,067 (-)NCBICelera
Cytogenetic Map15p14NCBI
RNASE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,801,228 - 20,802,844 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,801,228 - 20,802,855 (-)EnsemblGRCh38hg38GRCh38
GRCh371421,269,387 - 21,271,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,339,355 - 20,340,876 (-)NCBINCBI36Build 36hg18NCBI36
Build 341420,339,355 - 20,340,876NCBI
Celera141,130,381 - 1,131,902 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,390,522 - 1,392,043 (-)NCBIHuRef
CHM1_11421,271,658 - 21,273,179 (-)NCBICHM1_1
T2T-CHM13v2.01414,998,670 - 15,000,286 (-)NCBIT2T-CHM13v2.0
Rnase1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,382,459 - 51,384,224 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,382,455 - 51,384,242 (-)EnsemblGRCm39 Ensembl
GRCm381451,145,002 - 51,146,767 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,144,998 - 51,146,785 (-)EnsemblGRCm38mm10GRCm38
MGSCv371451,764,677 - 51,766,442 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361450,066,953 - 50,068,718 (-)NCBIMGSCv36mm8
Celera1447,439,042 - 47,440,804 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.4NCBI
RNASE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,298,976 - 22,300,905 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,515,463 - 21,517,392 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,663,595 - 1,665,121 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,719,885 - 19,746,621 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,720,127 - 19,720,597 (-)Ensemblpanpan1.1panPan2
LOC475395
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,034,337 - 18,065,925 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,037,298 - 18,066,333 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,522,914 - 18,524,349 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,281,909 - 18,326,869 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,298,180 - 18,299,615 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,979,542 - 17,980,977 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,035,593 - 18,037,028 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,163,424 - 18,164,859 (-)NCBIUU_Cfam_GSD_1.0
Rnase1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,181,705 - 32,183,432 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493688091,088 - 92,720 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493688091,085 - 92,743 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNASE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,213,005 - 78,214,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,199,007 - 78,214,832 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103231361
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,312,858 - 21,314,712 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,313,095 - 21,313,553 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,116,644 - 25,118,609 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

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Variants in Rnase1
78 total Variants

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:32
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000041822
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat

1 to 10 of 25 rows



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 6 10 23 25 14 6 14 6 38 15 2 6 7 11



Ensembl Acc Id: ENSRNOT00000082938   ⟹   ENSRNOP00000072263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,361,927 - 24,363,624 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086427   ⟹   ENSRNOP00000068653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,074,953 - 28,075,411 (+)Ensembl
RefSeq Acc Id: NM_001029904   ⟹   NP_001025075
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,835,436 - 26,837,145 (-)NCBI
mRatBN7.21524,361,924 - 24,363,633 (-)NCBI
Rnor_5.01531,897,124 - 31,898,675 (-)NCBI
RGSC_v3.41527,123,440 - 27,124,991 (-)RGD
Celera1524,679,524 - 24,681,067 (-)RGD
Sequence:
Protein RefSeqs NP_001025075 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAB41484 (Get FASTA)   NCBI Sequence Viewer  
  EDL88443 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000068653
  ENSRNOP00000072263.2
GenBank Protein P00684 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001025075   ⟸   NM_001029904
- Peptide Label: precursor
- UniProtKB: P00684 (UniProtKB/Swiss-Prot),   A6KED8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068653   ⟸   ENSRNOT00000086427
Ensembl Acc Id: ENSRNOP00000072263   ⟸   ENSRNOT00000082938
Ribonuclease A-domain

Name Modeler Protein Id AA Range Protein Structure
AF-P00684-F1-model_v2 AlphaFold P00684 1-152 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 23 of 23 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14025 BioCyc
Ensembl Genes ENSRNOG00000053633 Ensembl
  ENSRNOG00000063584 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000082938.2 UniProtKB/Swiss-Prot
  ENSRNOT00000086427 ENTREZGENE
Gene3D-CATH 3.10.130.10 UniProtKB/Swiss-Prot
InterPro RNaseA UniProtKB/Swiss-Prot
  RNaseA-like_dom_sf UniProtKB/Swiss-Prot
  RNaseA_AS UniProtKB/Swiss-Prot
  RNaseA_domain UniProtKB/Swiss-Prot
NCBI Gene Rnase1 ENTREZGENE
PANTHER PTHR11437 UniProtKB/Swiss-Prot
  RIBONUCLEASE PANCREATIC UniProtKB/Swiss-Prot
Pfam RnaseA UniProtKB/Swiss-Prot
PhenoGen Rnase1 PhenoGen
PRINTS RIBONUCLEASE UniProtKB/Swiss-Prot
PROSITE RNASE_PANCREATIC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000053633 RatGTEx
  ENSRNOG00000063584 RatGTEx
SMART RNAse_Pc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54076 UniProtKB/Swiss-Prot
UniProt A6KED8 ENTREZGENE, UniProtKB/TrEMBL
  P00684 ENTREZGENE, UniProtKB/Swiss-Prot
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Rnase1  ribonuclease A family member 1, pancreatic  LOC103690354  ribonuclease pancreatic beta-type  Data merged from RGD:9117758 737654 PROVISIONAL
2016-01-27 Rnase1  ribonuclease A family member 1, pancreatic  Rnase1  ribonuclease, RNase A family, 1 (pancreatic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103690354  ribonuclease pancreatic beta-type      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Rnase1  ribonuclease, RNase A family, 1 (pancreatic)  Rib1  ribonuclease, RNase A family, 1  Symbol and Name updated 1299863 APPROVED
2002-06-10 Rib1  ribonuclease, RNase A family, 1      Name updated 70584 APPROVED

Note Type Note Reference
gene_protein synthesized as a secretory pre-ribonuclease of 152 amino acids 69967