Mlip (muscular LMNA-interacting protein) - Rat Genome Database

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Gene: Mlip (muscular LMNA-interacting protein) Rattus norvegicus
Analyze
Symbol: Mlip
Name: muscular LMNA-interacting protein
RGD ID: 1590513
Description: Predicted to enable lamin binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of cardiac muscle hypertrophy in response to stress; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in PML body; nuclear envelope; and sarcolemma. Orthologous to human MLIP (muscular LMNA interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CIP; LOC681849; LOC691933; similar to Protein C6orf142 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8886,815,491 - 87,085,117 (-)NCBIGRCr8
mRatBN7.2877,935,087 - 78,204,725 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl877,935,079 - 78,204,254 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx883,419,251 - 83,575,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0881,695,893 - 81,852,440 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0879,518,592 - 79,675,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0884,409,957 - 84,634,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl884,434,784 - 84,632,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0883,981,876 - 84,206,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,082,936 - 82,201,670 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera877,693,077 - 77,954,209 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MlipRatautosomal dominant intellectual developmental disorder 64  ISOMLIP (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual developmental disorder and autosomal dominant 64ClinVarPMID:25741868 and PMID:34581780
MlipRatgenetic disease  ISOMLIP (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
MlipRatMyopathy with Myalgia, increased Serum Creatine Kinase, and with or without Episodic Rhabdomyolysis 1  ISOMLIP (Homo sapiens)8554872ClinVar Annotator: match by term: Myopathy with myalgia more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MlipRatMyopathy with Myalgia, increased Serum Creatine Kinase, and with or without Episodic Rhabdomyolysis 1  ISOMLIP (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MlipRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOMlip (Mus musculus)6480464[2 more ...CTDPMID:25510870
MlipRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOMlip (Mus musculus)6480464[2 more ...CTDPMID:25510870
MlipRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of MLIP mRNACTDPMID:32109520
MlipRat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
MlipRat4,4'-sulfonyldiphenol multiple interactionsISOMLIP (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in increased methylation of MLIP geneCTDPMID:31601247
MlipRatacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of MLIP mRNACTDPMID:28959563
MlipRataflatoxin B1 decreases expressionISOMLIP (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of MLIP mRNACTDPMID:27153756 and PMID:32234424
MlipRataflatoxin B1 decreases methylationISOMLIP (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of MLIP geneCTDPMID:27153756
MlipRatalpha-Zearalanol decreases expressionEXP 6480464Zeranol results in decreased expression of MLIP mRNACTDPMID:35163327
MlipRatalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MLIP mRNACTDPMID:35163327
MlipRatarotinoid acid multiple interactionsISOMLIP (Homo sapiens)6480464[4-(2-(5 more ...CTDPMID:34480604
MlipRatarsenous acid decreases expressionISOMLIP (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of MLIP mRNACTDPMID:26705709
MlipRatatrazine affects methylationEXP 6480464Atrazine affects the methylation of MLIP geneCTDPMID:28931070
MlipRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of MLIP mRNACTDPMID:25181051
MlipRatbisphenol A increases expressionISOMLIP (Homo sapiens)6480464bisphenol A results in increased expression of MLIP proteinCTDPMID:37567409
MlipRatCHIR 99021 multiple interactionsISOMLIP (Homo sapiens)6480464[4-(2-(5 more ...CTDPMID:34480604
MlipRatcortisol multiple interactionsISOMLIP (Homo sapiens)6480464[4-(2-(5 more ...CTDPMID:34480604
MlipRatcyclosporin A decreases expressionISOMLIP (Homo sapiens)6480464Cyclosporine results in decreased expression of MLIP mRNACTDPMID:20106945
MlipRatdiarsenic trioxide decreases expressionISOMLIP (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of MLIP mRNACTDPMID:26705709
MlipRatdoxorubicin decreases expressionISOMLIP (Homo sapiens)6480464Doxorubicin results in decreased expression of MLIP mRNACTDPMID:29803840

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Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MlipRatnegative regulation of cardiac muscle hypertrophy involved_inISSUniProtKB:Q5FW521600115GO_REF:0000024UniProtGO_REF:0000024
MlipRatnegative regulation of cardiac muscle hypertrophy acts_upstream_of_or_withinIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnegative regulation of cardiac muscle hypertrophy acts_upstream_of_or_withinISOMlip (Mus musculus)1624291 PMID:22343712RGDPMID:22343712
MlipRatnegative regulation of cardiac muscle hypertrophy in response to stress involved_inISOMlip (Mus musculus)1624291 PMID:26359501 and PMID:26436652RGDPMID:26359501 and PMID:26436652
MlipRatnegative regulation of cardiac muscle hypertrophy in response to stress involved_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnegative regulation of transcription by RNA polymerase II involved_inISSUniProtKB:Q5FW521600115GO_REF:0000024UniProtGO_REF:0000024
MlipRatnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOMlip (Mus musculus)1624291MGI:101791 PMID:22343712RGDPMID:22343712
MlipRatpositive regulation of transcription by RNA polymerase II involved_inISSUniProtKB:P613721600115GO_REF:0000024UniProtGO_REF:0000024
MlipRattranscription by RNA polymerase II acts_upstream_ofISOMlip (Mus musculus)1624291MGI:101791 PMID:22343712RGDPMID:22343712
MlipRattranscription by RNA polymerase II acts_upstream_ofIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 11 of 11 rows

Cellular Component
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
MlipRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
MlipRatcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
MlipRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
MlipRatnuclear envelope located_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnuclear envelope located_inIEAUniProtKB-SubCell:SL-01781600115GO_REF:0000044UniProtGO_REF:0000044
MlipRatnuclear envelope located_inISOMlip (Mus musculus)1624291 PMID:21498514RGDPMID:21498514
MlipRatnuclear lumen located_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnuclear lumen located_inISOMlip (Mus musculus)1624291 PMID:21498514RGDPMID:21498514
MlipRatnucleus located_inISOMlip (Mus musculus)1624291 PMID:22343712 and PMID:26436652RGDPMID:22343712 and PMID:26436652
MlipRatnucleus located_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
MlipRatnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
MlipRatnucleus located_inISSUniProtKB:Q5FW521600115GO_REF:0000024UniProtGO_REF:0000024
MlipRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
MlipRatPML body located_inISOMlip (Mus musculus)1624291 PMID:21498514RGDPMID:21498514
MlipRatPML body located_inIEAUniProtKB-SubCell:SL-04651600115GO_REF:0000044UniProtGO_REF:0000044
MlipRatPML body located_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatsarcolemma located_inIEAUniProtKB-SubCell:SL-02381600115GO_REF:0000044UniProtGO_REF:0000044
MlipRatsarcolemma located_inIEAUniProtKB:Q5FW52 and ensembl:ENSMUSP000001388641600115GO_REF:0000107EnsemblGO_REF:0000107
MlipRatsarcolemma located_inISOMlip (Mus musculus)1624291 PMID:26359501RGDPMID:26359501
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Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:21498514   PMID:22343712   PMID:26359501   PMID:26436652   PMID:31505169   PMID:35352799  



Mlip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8886,815,491 - 87,085,117 (-)NCBIGRCr8
mRatBN7.2877,935,087 - 78,204,725 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl877,935,079 - 78,204,254 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx883,419,251 - 83,575,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0881,695,893 - 81,852,440 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0879,518,592 - 79,675,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0884,409,957 - 84,634,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl884,434,784 - 84,632,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0883,981,876 - 84,206,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,082,936 - 82,201,670 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera877,693,077 - 77,954,209 (-)NCBICelera
Cytogenetic Map8q24NCBI
MLIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38654,018,970 - 54,266,280 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl653,929,982 - 54,266,280 (+)EnsemblGRCh38hg38GRCh38
GRCh37653,883,768 - 54,131,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36653,991,673 - 54,239,037 (+)NCBINCBI36Build 36hg18NCBI36
Build 34653,991,747 - 54,239,035NCBI
Celera655,545,893 - 55,793,289 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef653,716,745 - 53,964,412 (+)NCBIHuRef
CHM1_1653,885,511 - 54,126,906 (+)NCBICHM1_1
T2T-CHM13v2.0653,858,907 - 54,106,381 (+)NCBIT2T-CHM13v2.0
Mlip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39977,009,366 - 77,260,062 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl977,009,363 - 77,260,251 (-)EnsemblGRCm39 Ensembl
GRCm38977,102,084 - 77,352,782 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl977,102,081 - 77,352,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37976,949,891 - 77,195,677 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36976,889,909 - 77,035,661 (-)NCBIMGSCv36mm8
Celera974,274,590 - 74,527,305 (-)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.67NCBI
Mlip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554111,852,895 - 2,100,617 (-)NCBIChiLan1.0ChiLan1.0
MLIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2568,572,108 - 68,739,870 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1664,448,582 - 64,616,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0653,574,541 - 53,823,395 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1655,210,088 - 55,459,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl655,202,674 - 55,457,640 (+)Ensemblpanpan1.1panPan2
MLIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11221,501,727 - 21,757,760 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1221,502,561 - 21,757,764 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1221,392,514 - 21,649,155 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,997,540 - 22,260,928 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,998,353 - 22,260,925 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11221,489,952 - 21,747,168 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01221,599,994 - 21,863,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01221,737,977 - 21,994,987 (+)NCBIUU_Cfam_GSD_1.0
Mlip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494657,023,182 - 57,243,557 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364766,716,661 - 6,835,131 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364766,715,607 - 6,936,978 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl726,561,359 - 26,793,724 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1726,562,802 - 26,801,817 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2731,068,707 - 31,236,064 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MLIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11717,254,118 - 17,512,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1717,252,186 - 17,503,406 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605823,430,902 - 23,587,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mlip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248501,296,435 - 1,606,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Mlip
1689 total Variants

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:97
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000064754, ENSRNOT00000067627
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85009524982460899Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)82824291299525068Rat

1 to 10 of 57 rows
D8Rat24  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8887,018,553 - 87,018,707 (+)Marker Load Pipeline
mRatBN7.2878,138,158 - 78,138,314 (+)MAPPERmRatBN7.2
Rnor_6.0884,569,165 - 84,569,318NCBIRnor6.0
Rnor_5.0884,140,683 - 84,140,836UniSTSRnor5.0
RGSC_v3.4882,246,890 - 82,247,243RGDRGSC3.4
RGSC_v3.4882,247,051 - 82,247,204UniSTSRGSC3.4
RGSC_v3.1882,266,105 - 82,266,258RGD
Celera877,890,637 - 77,890,790UniSTS
RH 3.4 Map8897.39UniSTS
RH 3.4 Map8897.39RGD
RH 2.0 Map8767.5RGD
SHRSP x BN Map845.61RGD
Cytogenetic Map8q24-q31UniSTS
D9Mit319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2878,138,147 - 78,138,287 (+)MAPPERmRatBN7.2
Rnor_6.0884,569,154 - 84,569,291NCBIRnor6.0
Rnor_5.0884,140,672 - 84,140,809UniSTSRnor5.0
RGSC_v3.4882,247,040 - 82,247,177UniSTSRGSC3.4
Celera877,890,626 - 77,890,763UniSTS
Cytogenetic Map8q24-q31UniSTS
AI713303  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map8924.89UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 11 49 105 61 60 29 21 29 6 168 93 85 30 57 31


1 to 30 of 48 rows
RefSeq Transcripts NM_001399373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008757820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008757821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 48 rows

Ensembl Acc Id: ENSRNOT00000064754   ⟹   ENSRNOP00000061707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,079 - 78,201,739 (-)Ensembl
Rnor_6.0 Ensembl884,434,784 - 84,506,328 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076213   ⟹   ENSRNOP00000068241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,089 - 78,091,472 (-)Ensembl
Rnor_6.0 Ensembl884,434,784 - 84,522,588 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076942   ⟹   ENSRNOP00000068377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl878,001,046 - 78,201,739 (-)Ensembl
Rnor_6.0 Ensembl884,434,784 - 84,632,817 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101165   ⟹   ENSRNOP00000088810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,079 - 78,091,593 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105297   ⟹   ENSRNOP00000097271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,395 - 78,091,593 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000110692   ⟹   ENSRNOP00000078605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,395 - 78,204,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113615   ⟹   ENSRNOP00000095106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,089 - 78,091,472 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117285   ⟹   ENSRNOP00000080719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,079 - 78,204,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000120266   ⟹   ENSRNOP00000076453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl877,935,079 - 78,204,254 (-)Ensembl
RefSeq Acc Id: NM_001399373   ⟹   NP_001386302
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,971,873 (-)NCBI
mRatBN7.2877,935,087 - 78,091,475 (-)NCBI
RefSeq Acc Id: XM_039082514   ⟹   XP_038938442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,085,117 (-)NCBI
mRatBN7.2877,935,087 - 78,204,725 (-)NCBI
RefSeq Acc Id: XM_039082515   ⟹   XP_038938443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,085,117 (-)NCBI
mRatBN7.2877,935,087 - 78,204,725 (-)NCBI
RefSeq Acc Id: XM_039082516   ⟹   XP_038938444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,667 (-)NCBI
mRatBN7.2877,935,087 - 78,101,288 (-)NCBI
RefSeq Acc Id: XM_039082517   ⟹   XP_038938445
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,671 (-)NCBI
mRatBN7.2877,935,087 - 78,101,290 (-)NCBI
RefSeq Acc Id: XM_039082518   ⟹   XP_038938446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,661 (-)NCBI
mRatBN7.2877,935,087 - 78,101,285 (-)NCBI
RefSeq Acc Id: XM_039082519   ⟹   XP_038938447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,664 (-)NCBI
mRatBN7.2877,935,087 - 78,101,287 (-)NCBI
RefSeq Acc Id: XM_039082520   ⟹   XP_038938448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,666 (-)NCBI
mRatBN7.2877,935,087 - 78,101,288 (-)NCBI
RefSeq Acc Id: XM_039082521   ⟹   XP_038938449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,665 (-)NCBI
mRatBN7.2877,935,087 - 78,101,287 (-)NCBI
RefSeq Acc Id: XM_039082522   ⟹   XP_038938450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,664 (-)NCBI
mRatBN7.2877,935,087 - 78,101,287 (-)NCBI
RefSeq Acc Id: XM_039082523   ⟹   XP_038938451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,971,873 (-)NCBI
mRatBN7.2877,935,087 - 78,091,475 (-)NCBI
RefSeq Acc Id: XM_039082524   ⟹   XP_038938452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,664 (-)NCBI
mRatBN7.2877,935,087 - 78,101,286 (-)NCBI
RefSeq Acc Id: XM_039082525   ⟹   XP_038938453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,662 (-)NCBI
mRatBN7.2877,935,087 - 78,101,285 (-)NCBI
RefSeq Acc Id: XM_039082527   ⟹   XP_038938455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,971,873 (-)NCBI
mRatBN7.2877,935,087 - 78,091,475 (-)NCBI
RefSeq Acc Id: XM_039082528   ⟹   XP_038938456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,628 (-)NCBI
mRatBN7.2877,935,087 - 78,101,258 (-)NCBI
RefSeq Acc Id: XM_039082529   ⟹   XP_038938457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,971,873 (-)NCBI
mRatBN7.2877,935,087 - 78,091,475 (-)NCBI
RefSeq Acc Id: XM_063266132   ⟹   XP_063122202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,075,313 (-)NCBI
RefSeq Acc Id: XM_063266133   ⟹   XP_063122203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 86,981,647 (-)NCBI
RefSeq Acc Id: XM_063266134   ⟹   XP_063122204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,083,962 (-)NCBI
RefSeq Acc Id: XM_063266135   ⟹   XP_063122205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,083,962 (-)NCBI
RefSeq Acc Id: XM_063266136   ⟹   XP_063122206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,083,962 (-)NCBI
RefSeq Acc Id: XM_063266137   ⟹   XP_063122207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8886,815,491 - 87,083,962 (-)NCBI
1 to 30 of 32 rows
Protein RefSeqs NP_001386302 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938442 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938443 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938444 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938445 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938446 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938447 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938448 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938449 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938450 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938451 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938452 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938453 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938455 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938456 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938457 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122202 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122203 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122204 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122205 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122206 (Get FASTA)   NCBI Sequence Viewer  
  XP_063122207 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein A0A096MK47 (Get FASTA)   NCBI Sequence Viewer  
  AAH92625 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000061707.4
  ENSRNOP00000068241
  ENSRNOP00000076453
  ENSRNOP00000080719
  ENSRNOP00000095106
  ENSRNOP00000097271
1 to 30 of 32 rows
1 to 5 of 31 rows
1 to 5 of 31 rows
Ensembl Acc Id: ENSRNOP00000068377   ⟸   ENSRNOT00000076942
Ensembl Acc Id: ENSRNOP00000068241   ⟸   ENSRNOT00000076213
Ensembl Acc Id: ENSRNOP00000061707   ⟸   ENSRNOT00000064754
RefSeq Acc Id: XP_038938443   ⟸   XM_039082515
- Peptide Label: isoform X1
- UniProtKB: Q569A0 (UniProtKB/Swiss-Prot),   D4A3C4 (UniProtKB/Swiss-Prot),   A0A8I6ARD4 (UniProtKB/Swiss-Prot),   A0A096MK47 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038938442   ⟸   XM_039082514
- Peptide Label: isoform X1
- UniProtKB: Q569A0 (UniProtKB/Swiss-Prot),   D4A3C4 (UniProtKB/Swiss-Prot),   A0A8I6ARD4 (UniProtKB/Swiss-Prot),   A0A096MK47 (UniProtKB/Swiss-Prot)

Name Modeler Protein Id AA Range Protein Structure
AF-A0A096MK47-F1-model_v2 AlphaFold A0A096MK47 1-807 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13696142
Promoter ID:EPDNEW_R6660
Type:multiple initiation site
Name:Mlip_1
Description:muscular LMNA-interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0884,632,810 - 84,632,870EPDNEW


1 to 35 of 35 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-29794 BioCyc
Ensembl Genes ENSRNOG00000005934 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000064754.4 UniProtKB/Swiss-Prot
  ENSRNOT00000076213 ENTREZGENE
  ENSRNOT00000105297 ENTREZGENE
  ENSRNOT00000105297.1 UniProtKB/Swiss-Prot
  ENSRNOT00000113615 ENTREZGENE
  ENSRNOT00000117285 ENTREZGENE
  ENSRNOT00000120266 ENTREZGENE
  ENSRNOT00000143920 ENTREZGENE
IMAGE_CLONE IMAGE:7314232 IMAGE-MGC_LOAD
InterPro MLIP UniProtKB/Swiss-Prot
MGC_CLONE MGC:109316 IMAGE-MGC_LOAD
NCBI Gene 681849 ENTREZGENE
PANTHER MUSCULAR LMNA-INTERACTING PROTEIN UniProtKB/Swiss-Prot
  PTHR31514 UniProtKB/Swiss-Prot
Pfam MLIP UniProtKB/Swiss-Prot
PhenoGen Mlip PhenoGen
RatGTEx ENSRNOG00000005934 RatGTEx
UniProt A0A096MJS3 ENTREZGENE, UniProtKB/TrEMBL
  A0A096MK47 ENTREZGENE
  A0A5H1ZRU6_RAT UniProtKB/TrEMBL
  A0A8I5Y544_RAT UniProtKB/TrEMBL
  A0A8I5ZL83_RAT UniProtKB/TrEMBL
  A0A8I5ZRC1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8U5_RAT UniProtKB/TrEMBL
  A0A8I6AMD7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ARD4 ENTREZGENE
  A0A8L2UP94_RAT UniProtKB/TrEMBL
  D4A3C4 ENTREZGENE
  MLIP_RAT UniProtKB/Swiss-Prot
  Q569A0 ENTREZGENE
UniProt Secondary A0A8I6ARD4 UniProtKB/Swiss-Prot
  D4A3C4 UniProtKB/Swiss-Prot
  Q569A0 UniProtKB/Swiss-Prot
1 to 35 of 35 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Mlip  muscular LMNA-interacting protein  LOC691933  similar to Protein C6orf142 homolog  Data merged from RGD:1593349 737654 PROVISIONAL
2013-08-09 Mlip  muscular LMNA-interacting protein  LOC681849  similar to Protein C6orf142 homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC691933  similar to Protein C6orf142 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681849  similar to Protein C6orf142 homolog      Symbol and Name status set to provisional 70820 PROVISIONAL