Mlip (muscular LMNA interacting protein) - Rat Genome Database

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Gene: Mlip (muscular LMNA interacting protein) Heterocephalus glaber
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Symbol: Mlip
Name: muscular LMNA interacting protein
RGD ID: 18900537
Description: ENCODES a protein that exhibits lamin binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of cardiac muscle hypertrophy (ortholog); negative regulation of cardiac muscle hypertrophy in response to stress (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Autosomal Dominant Intellectual Developmental Disorder 64 (ortholog); genetic disease (ortholog); Myopathy with Myalgia, increased Serum Creatine Kinase, and with or without Episodic Rhabdomyolysis 1 (ortholog); FOUND IN nuclear envelope (ortholog); nuclear lumen (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: muscular LMNA-interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248501,296,435 - 1,606,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Mlip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248501,296,435 - 1,606,630 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MLIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38654,018,970 - 54,266,280 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl653,929,982 - 54,266,280 (+)EnsemblGRCh38hg38GRCh38
GRCh37653,883,768 - 54,131,078 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36653,991,673 - 54,239,037 (+)NCBINCBI36Build 36hg18NCBI36
Build 34653,991,747 - 54,239,035NCBI
Celera655,545,893 - 55,793,289 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef653,716,745 - 53,964,412 (+)NCBIHuRef
CHM1_1653,885,511 - 54,126,906 (+)NCBICHM1_1
T2T-CHM13v2.0653,858,907 - 54,106,381 (+)NCBIT2T-CHM13v2.0
Mlip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39977,009,366 - 77,260,062 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl977,009,363 - 77,260,251 (-)EnsemblGRCm39 Ensembl
GRCm38977,102,084 - 77,352,782 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl977,102,081 - 77,352,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv37976,949,891 - 77,195,677 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36976,889,909 - 77,035,661 (-)NCBIMGSCv36mm8
Celera974,274,590 - 74,527,305 (-)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.67NCBI
Mlip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8886,815,491 - 87,085,117 (-)NCBIGRCr8
mRatBN7.2877,935,087 - 78,204,725 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl877,935,079 - 78,204,254 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx883,419,251 - 83,575,810 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0881,695,893 - 81,852,440 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0879,518,592 - 79,675,147 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0884,409,957 - 84,634,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl884,434,784 - 84,632,817 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0883,981,876 - 84,206,700 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4882,082,936 - 82,201,670 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera877,693,077 - 77,954,209 (-)NCBICelera
Cytogenetic Map8q24NCBI
Mlip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554111,852,895 - 2,100,617 (-)NCBIChiLan1.0ChiLan1.0
MLIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2568,572,108 - 68,739,870 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1664,448,582 - 64,616,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0653,574,541 - 53,823,395 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1655,210,088 - 55,459,037 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl655,202,674 - 55,457,640 (+)Ensemblpanpan1.1panPan2
MLIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11221,501,727 - 21,757,760 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1221,502,561 - 21,757,764 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1221,392,514 - 21,649,155 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01221,997,540 - 22,260,928 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1221,998,353 - 22,260,925 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11221,489,952 - 21,747,168 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01221,599,994 - 21,863,302 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01221,737,977 - 21,994,987 (+)NCBIUU_Cfam_GSD_1.0
Mlip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494657,023,182 - 57,243,557 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364766,716,661 - 6,835,131 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364766,715,607 - 6,936,978 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MLIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl726,561,359 - 26,793,724 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1726,562,802 - 26,801,817 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2731,068,707 - 31,236,064 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MLIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11717,254,118 - 17,512,265 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1717,252,186 - 17,503,406 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605823,430,902 - 23,587,741 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021247617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021247621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01089609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01089625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH170754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_021247617   ⟹   XP_021103276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248501,313,611 - 1,606,630 (+)NCBI
RefSeq Acc Id: XM_021247618   ⟹   XP_021103277
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248501,313,619 - 1,606,630 (+)NCBI
RefSeq Acc Id: XM_021247619   ⟹   XP_021103278
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248501,296,437 - 1,606,630 (+)NCBI
RefSeq Acc Id: XM_021247620   ⟹   XP_021103279
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248501,296,437 - 1,606,630 (+)NCBI
RefSeq Acc Id: XM_021247621   ⟹   XP_021103280
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248501,296,435 - 1,606,630 (+)NCBI
RefSeq Acc Id: XP_021103280   ⟸   XM_021247621
- Peptide Label: isoform X3
- UniProtKB: A0AAX6S4J9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103279   ⟸   XM_021247620
- Peptide Label: isoform X3
- UniProtKB: A0AAX6S4J9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103278   ⟸   XM_021247619
- Peptide Label: isoform X3
- UniProtKB: A0AAX6S4J9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103276   ⟸   XM_021247617
- Peptide Label: isoform X1
- UniProtKB: A0AAX6S2D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021103277   ⟸   XM_021247618
- Peptide Label: isoform X2
- UniProtKB: A0AAX6S2U3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
NCBI Gene Mlip ENTREZGENE
UniProt A0AAX6S2D4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S2U3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S4J9 ENTREZGENE, UniProtKB/TrEMBL