Il34 (interleukin 34) - Rat Genome Database

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Gene: Il34 (interleukin 34) Rattus norvegicus
Analyze
Symbol: Il34
Name: interleukin 34
RGD ID: 1586038
Description: Predicted to enable identical protein binding activity and macrophage colony-stimulating factor receptor binding activity. Predicted to be involved in several processes, including interleukin-34-mediated signaling pathway; positive regulation of cell development; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within positive regulation of MAP kinase activity and positive regulation of protein tyrosine kinase activity. Predicted to be active in extracellular space. Orthologous to human IL34 (interleukin 34); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IL-34; interleukin-34; LOC498951; MGC112852; similar to 2010004A03Rik protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,624,368 - 55,690,576 (-)NCBIGRCr8
mRatBN7.21938,714,990 - 38,782,749 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,714,991 - 38,764,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,520,176 - 45,534,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,173,544 - 46,187,927 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,484,111 - 48,498,359 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01940,855,537 - 40,905,007 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1940,855,433 - 40,904,121 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01951,680,005 - 51,729,266 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,662,723 - 40,676,634 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1938,108,703 - 38,123,111 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il34Ratautosomal dominant dyskeratosis congenita 6  ISOIL34 (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenita and autosomal dominant 6ClinVarPMID:28492532
Il34RatCharcot-Marie-Tooth disease type 2  ISOIL34 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 2ClinVarPMID:28492532
Il34RatChromosome 16q12 Duplication Syndrome  ISOIL34 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 16q12 duplication syndromeClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il34Ratpolycystic ovary syndrome  ISOIL34 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21411543

1 to 20 of 58 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il34Rat1,2-dichloroethane decreases expressionISOIl34 (Mus musculus)6480464ethylene dichloride results in decreased expression of IL34 mRNACTDPMID:28960355
Il34Rat17beta-estradiol decreases expressionISOIl34 (Mus musculus)6480464Estradiol results in decreased expression of IL34 mRNACTDPMID:39298647
Il34Rat17beta-estradiol decreases expressionISOIL34 (Homo sapiens)6480464Estradiol results in decreased expression of IL34 mRNACTDPMID:36828454
Il34Rat2,2',5,5'-tetrachlorobiphenyl decreases expressionISOIL34 (Homo sapiens)64804642 more ...CTDPMID:36804509
Il34Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Il34Rat2-hydroxypropanoic acid decreases expressionISOIL34 (Homo sapiens)6480464Lactic Acid results in decreased expression of IL34 mRNACTDPMID:30851411
Il34Rat3,3',4,4',5-pentachlorobiphenyl increases expressionEXP 64804643 more ...CTDPMID:32119087
Il34Rat3,3',4,4',5-pentachlorobiphenyl increases expressionISOIL34 (Homo sapiens)64804643 more ...CTDPMID:35618242
Il34Rat3,4-methylenedioxymethamphetamine increases expressionISOIl34 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of IL34 mRNACTDPMID:20188158
Il34Rat4,4'-sulfonyldiphenol increases expressionISOIl34 (Mus musculus)6480464bisphenol S results in increased expression of IL34 mRNACTDPMID:38908815
Il34Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of IL34 mRNACTDPMID:36041667
Il34Rat4,4'-sulfonyldiphenol increases methylationISOIl34 (Mus musculus)6480464bisphenol S results in increased methylation of IL34 exonCTDPMID:33297965
Il34Rat4-hydroxyphenyl retinamide decreases expressionISOIl34 (Mus musculus)6480464Fenretinide results in decreased expression of IL34 mRNACTDPMID:28973697
Il34Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of IL34 mRNACTDPMID:30047161
Il34Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of IL34 mRNACTDPMID:28959563
Il34Ratall-trans-retinoic acid multiple interactionsISOIl34 (Mus musculus)6480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of IL34 mRNACTDPMID:36189433
Il34Ratamitrole increases expressionEXP 6480464Amitrole results in increased expression of IL34 mRNACTDPMID:30047161
Il34Ratatrazine affects methylationEXP 6480464Atrazine affects the methylation of IL34 geneCTDPMID:28931070
Il34Ratbenzalkonium chloride decreases expressionISOIl34 (Mus musculus)6480464Benzalkonium Compounds results in decreased expression of IL34 mRNACTDPMID:30171875
Il34Ratbenzo[a]pyrene increases expressionISOIl34 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of IL34 mRNACTDPMID:23735875

1 to 20 of 58 rows

Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il34Ratimmune system process involved_inIEAUniProtKB-KW:KW-03911600115GO_REF:0000043UniProtGO_REF:0000043
Il34Ratinflammatory response involved_inIEAUniProtKB-KW:KW-03951600115GO_REF:0000043UniProtGO_REF:0000043
Il34Ratinnate immune response involved_inIEAUniProtKB-KW:KW-03991600115GO_REF:0000043UniProtGO_REF:0000043
Il34Ratinterleukin-34-mediated signaling pathway involved_inISOIL34 (Homo sapiens)1624291 PMID:26754294RGDPMID:26754294
Il34Ratmicroglial cell proliferation involved_inISOIl34 (Mus musculus)1624291UniProtKB:P09581 and PMID:23392676RGDPMID:23392676
Il34Ratpositive regulation of cell population proliferation involved_inISOIL34 (Homo sapiens)1624291 PMID:18467591RGDPMID:18467591
Il34Ratpositive regulation of cell population proliferation involved_inIEAInterPro:IPR0204151600115GO_REF:0000002InterProGO_REF:0000002
Il34Ratpositive regulation of cell population proliferation involved_inIBAPANTHER:PTN002823014 and UniProtKB:Q6ZMJ41600115GO_REF:0000033GO_CentralGO_REF:0000033
Il34Ratpositive regulation of cell population proliferation involved_inISSUniProtKB:Q6ZMJ48554272PMID:18467591UniProt 
Il34Ratpositive regulation of gene expression involved_inISOIl34 (Mus musculus)1624291 PMID:30687013RGDPMID:30687013
Il34Ratpositive regulation of macrophage chemotaxis acts_upstream_ofISOIL34 (Homo sapiens)1624291 PMID:26754294RGDPMID:26754294
Il34Ratpositive regulation of macrophage differentiation involved_inISOIL34 (Homo sapiens)1624291 PMID:23409120RGDPMID:23409120
Il34Ratpositive regulation of macrophage differentiation involved_inIBAPANTHER:PTN002823014 and UniProtKB:Q6ZMJ41600115GO_REF:0000033GO_CentralGO_REF:0000033
Il34Ratpositive regulation of macrophage proliferation acts_upstream_ofISOIL34 (Homo sapiens)1624291 PMID:26754294RGDPMID:26754294
Il34Ratpositive regulation of MAPK cascade acts_upstream_of_or_withinISOIL34 (Homo sapiens)1624291 PMID:26754294RGDPMID:26754294
Il34Ratpositive regulation of monocyte differentiation involved_inISOIL34 (Homo sapiens)1624291 PMID:23409120RGDPMID:23409120
Il34Ratpositive regulation of monocyte differentiation involved_inIBAPANTHER:PTN002823014 and UniProtKB:Q6ZMJ41600115GO_REF:0000033GO_CentralGO_REF:0000033
Il34Ratpositive regulation of oligodendrocyte differentiation involved_inISSUniProtKB:Q8R1R41600115GO_REF:0000024UniProtGO_REF:0000024
Il34Ratpositive regulation of oligodendrocyte differentiation involved_inISOIl34 (Mus musculus)1624291 PMID:27445335RGDPMID:27445335
Il34Ratpositive regulation of protein phosphorylation involved_inISSUniProtKB:Q6ZMJ48554272PMID:18467591UniProt 
1 to 20 of 21 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Il34Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Il34Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Il34Ratextracellular space located_inISSUniProtKB:Q6ZMJ48554272PMID:18467591UniProt 
Il34Ratextracellular space located_inIEAUniProtKB-KW:KW-02021600115GO_REF:0000043UniProtGO_REF:0000043
Il34Ratextracellular space located_inIEAInterPro:IPR0204151600115GO_REF:0000002InterProGO_REF:0000002
Il34Ratextracellular space is_active_inIBAPANTHER:PTN002823014 and UniProtKB:Q6ZMJ41600115GO_REF:0000033GO_CentralGO_REF:0000033
Il34Ratextracellular space located_inISOIL34 (Homo sapiens)1624291 PMID:18467591RGDPMID:18467591


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Lin H, etal., Science. 2008 May 9;320(5877):807-11. doi: 10.1126/science.1154370.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:15489334   PMID:22483114   PMID:23392676   PMID:23409120   PMID:26389674   PMID:26754294   PMID:27445335   PMID:30687013   PMID:36030499  



Il34
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,624,368 - 55,690,576 (-)NCBIGRCr8
mRatBN7.21938,714,990 - 38,782,749 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,714,991 - 38,764,000 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,520,176 - 45,534,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,173,544 - 46,187,927 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,484,111 - 48,498,359 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01940,855,537 - 40,905,007 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1940,855,433 - 40,904,121 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01951,680,005 - 51,729,266 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,662,723 - 40,676,634 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1938,108,703 - 38,123,111 (-)NCBICelera
Cytogenetic Map19q12NCBI
IL34
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381670,579,899 - 70,660,682 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1670,579,895 - 70,660,682 (+)EnsemblGRCh38hg38GRCh38
GRCh371670,613,802 - 70,694,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361669,237,969 - 69,252,085 (+)NCBINCBI36Build 36hg18NCBI36
Celera1654,830,211 - 54,914,394 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1656,444,788 - 56,526,038 (+)NCBIHuRef
CHM1_11672,021,130 - 72,101,930 (+)NCBICHM1_1
T2T-CHM13v2.01676,391,088 - 76,471,868 (+)NCBIT2T-CHM13v2.0
Il34
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,467,809 - 111,532,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8111,468,461 - 111,532,556 (-)EnsemblGRCm39 Ensembl
GRCm388110,741,829 - 110,805,949 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8110,741,829 - 110,805,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv378113,265,729 - 113,329,803 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,628,517 - 113,692,549 (-)NCBIMGSCv36mm8
Celera8114,965,768 - 115,029,412 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.68NCBI
Il34
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,416,965 - 3,428,574 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,362,240 - 3,429,031 (+)NCBIChiLan1.0ChiLan1.0
IL34
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21883,505,787 - 83,583,507 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11689,439,379 - 89,512,788 (-)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1670,480,917 - 70,494,693 (+)Ensemblpanpan1.1panPan2
IL34
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1576,601,310 - 76,612,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl576,555,214 - 76,625,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha576,562,564 - 76,573,722 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0577,037,777 - 77,049,154 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl576,991,631 - 77,049,148 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1576,859,645 - 76,871,004 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0576,682,464 - 76,693,813 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0577,174,314 - 77,185,475 (+)NCBIUU_Cfam_GSD_1.0
Il34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934936,558,176 - 36,621,152 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647522,967,930 - 22,979,641 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647522,967,962 - 22,979,954 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL34
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,588,787 - 13,659,895 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,588,748 - 13,679,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,511,317 - 13,512,804 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IL34
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,731,330 - 53,802,142 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl553,731,379 - 53,801,650 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604716,529,863 - 16,614,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il34
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,861,018 - 12,867,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,793,797 - 12,867,591 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Il34
405 total Variants

Predicted Target Of
Summary Value
Count of predictions:399
Count of miRNA genes:224
Interacting mature miRNAs:263
Transcripts:ENSRNOT00000023823
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 18 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat

1 to 10 of 18 rows
RH127794  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,715,040 - 38,715,221 (-)MAPPERmRatBN7.2
Rnor_6.01940,904,133 - 40,904,313NCBIRnor6.0
Rnor_5.01951,728,392 - 51,728,572UniSTSRnor5.0
RGSC_v3.41940,662,774 - 40,662,954UniSTSRGSC3.4
Celera1938,108,754 - 38,108,934UniSTS
RH 3.4 Map19470.1UniSTS
Cytogenetic Map19q12UniSTS
BE120045  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21938,717,096 - 38,717,253 (-)MAPPERmRatBN7.2
Rnor_6.01940,902,101 - 40,902,257NCBIRnor6.0
Rnor_5.01951,726,360 - 51,726,516UniSTSRnor5.0
RGSC_v3.41940,664,830 - 40,664,986UniSTSRGSC3.4
Celera1938,110,810 - 38,110,966UniSTS
RH 3.4 Map19471.2UniSTS
Cytogenetic Map19q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 41 107 91 90 59 25 59 6 210 89 87 45 60 31



Ensembl Acc Id: ENSRNOT00000023823   ⟹   ENSRNOP00000023823
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1938,714,991 - 38,764,000 (-)Ensembl
Rnor_6.0 Ensembl1940,855,433 - 40,904,121 (+)Ensembl
RefSeq Acc Id: NM_001025766   ⟹   NP_001020937
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,368 - 55,638,605 (-)NCBI
mRatBN7.21938,714,990 - 38,729,226 (-)NCBI
Rnor_6.01940,890,544 - 40,904,364 (+)NCBI
Rnor_5.01951,680,005 - 51,729,266 (+)NCBI
RGSC_v3.41940,662,723 - 40,676,634 (-)RGD
Celera1938,108,703 - 38,123,111 (-)RGD
Sequence:
RefSeq Acc Id: XM_039097930   ⟹   XP_038953858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,368 - 55,688,428 (-)NCBI
mRatBN7.21938,714,990 - 38,779,042 (-)NCBI
RefSeq Acc Id: XM_039097931   ⟹   XP_038953859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,368 - 55,641,484 (-)NCBI
mRatBN7.21938,714,990 - 38,732,293 (-)NCBI
RefSeq Acc Id: XM_039097932   ⟹   XP_038953860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,368 - 55,688,426 (-)NCBI
mRatBN7.21938,714,990 - 38,779,053 (-)NCBI
RefSeq Acc Id: XM_039097933   ⟹   XP_038953861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,809 - 55,690,576 (-)NCBI
mRatBN7.21938,715,460 - 38,782,749 (-)NCBI
RefSeq Acc Id: XM_063278199   ⟹   XP_063134269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81955,624,368 - 55,688,114 (-)NCBI
RefSeq Acc Id: NP_001020937   ⟸   NM_001025766
- Peptide Label: precursor
- UniProtKB: Q4KM46 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023823   ⟸   ENSRNOT00000023823
RefSeq Acc Id: XP_038953860   ⟸   XM_039097932
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953858   ⟸   XM_039097930
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038953859   ⟸   XM_039097931
- Peptide Label: isoform X1

Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM46-F1-model_v2 AlphaFold Q4KM46 1-234 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5686 BioCyc
Ensembl Genes ENSRNOG00000017602 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000023823 ENTREZGENE
Gene3D-CATH 1.20.1250.80 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106821 IMAGE-MGC_LOAD
  IMAGE:7376793 IMAGE-MGC_LOAD
InterPro IL-34 UniProtKB/Swiss-Prot
  IL-34_sf UniProtKB/Swiss-Prot
KEGG Report rno:498951 UniProtKB/Swiss-Prot
MGC_CLONE MGC:112852 IMAGE-MGC_LOAD
  MGC:94787 IMAGE-MGC_LOAD
NCBI Gene 498951 ENTREZGENE
PANTHER INTERLEUKIN-34 UniProtKB/Swiss-Prot
  PTHR28606 UniProtKB/Swiss-Prot
Pfam IL34 UniProtKB/Swiss-Prot
PhenoGen Il34 PhenoGen
PRINTS INTRLEUKIN34 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017602 RatGTEx
UniProt A0A140TAD0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8A1UCG2_RAT UniProtKB/TrEMBL
  IL34_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Il34  interleukin 34  LOC498951  similar to 2010004A03Rik protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC498951  similar to 2010004A03Rik protein      Symbol and Name status set to provisional 70820 PROVISIONAL