Or7g23c (olfactory receptor family 7 subfamily G member 23C) - Rat Genome Database

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Gene: Or7g23c (olfactory receptor family 7 subfamily G member 23C) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or7g23c
Name: olfactory receptor family 7 subfamily G member 23C
RGD ID: 1333399
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. Orthologous to human OR7G1 (olfactory receptor family 7 subfamily G member 1); INTERACTS WITH acrylamide; DDT; vinclozolin.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100911849; LOC103693022; olfactory receptor 1135; olfactory receptor 7G1-like; olfactory receptor 7G2-like; olfactory receptor gene Olr1135; olfactory receptor Olr1135; Olr1135
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8825,084,693 - 25,085,631 (-)NCBIGRCr8
mRatBN7.2816,808,409 - 16,809,347 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl816,808,409 - 16,809,347 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx820,800,281 - 20,801,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0819,098,117 - 19,099,055 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0817,036,328 - 17,037,266 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0819,081,540 - 19,082,478 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl819,081,540 - 19,082,478 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl817,964,480 - 17,965,418 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0819,149,816 - 19,150,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4817,207,231 - 17,208,169 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1817,207,230 - 17,208,169 (-)NCBI
Celera818,225,463 - 18,226,401 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or7g23cRatacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of OR7G23C mRNACTDPMID:28959563
Or7g23cRatDDT decreases methylationEXP 6480464DDT results in decreased methylation of OR7G23C geneCTDPMID:30207508
Or7g23cRatvinclozolin decreases expressionEXP 6480464vinclozolin results in decreased expression of OR7G23C mRNACTDPMID:23869203


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or7g23cRatdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or7g23cRatdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or7g23cRatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or7g23cRatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or7g23cRatsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatsignal transduction involved_inIBAPANTHER:PTN001239850 and UniProtKB:P349821600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or7g23cRatmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or7g23cRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatplasma membrane is_active_inIBAPANTHER:PTN001239850 and UniProtKB:A6NND41600115GO_REF:0000033GO_CentralGO_REF:0000033
Or7g23cRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or7g23cRatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or7g23cRatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or7g23cRatolfactory receptor activity enablesIBAMGI:1333746 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or7g23cRatolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or7g23cRatolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or7g23cRattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Or7g23c
12 total Variants

Predicted Target Of
Summary Value
Count of predictions:168
Count of miRNA genes:66
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000072508, ENSRNOT00000073314
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558646Swd5Spike wave discharge measurement QTL 53.450.00036brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)81490675159906751Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)8971246341866876Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)8873663553736635Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)8470581049705810Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)8767057852670578Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)8470581049705810Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)8971222053356647Rat

1 to 10 of 21 rows





RefSeq Transcripts NM_001000878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000072508   ⟹   ENSRNOP00000066195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl817,964,480 - 17,965,418 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000073314   ⟹   ENSRNOP00000065893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl819,081,540 - 19,082,478 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000100952   ⟹   ENSRNOP00000087897
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl816,808,409 - 16,809,347 (-)Ensembl
RefSeq Acc Id: NM_001000878   ⟹   NP_001000878
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8825,084,693 - 25,085,631 (-)NCBI
mRatBN7.2816,808,409 - 16,809,347 (-)NCBI
Rnor_6.0819,081,540 - 19,082,478 (-)NCBI
Rnor_5.0819,149,816 - 19,150,754 (-)NCBI
RGSC_v3.4817,207,231 - 17,208,169 (-)RGD
Celera818,225,463 - 18,226,401 (-)RGD
Sequence:
Protein RefSeqs NP_001000878 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000087897
  ENSRNOP00000087897.1
RefSeq Acc Id: NP_001000878   ⟸   NM_001000878
- UniProtKB: M0R8T8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065893   ⟸   ENSRNOT00000073314
Ensembl Acc Id: ENSRNOP00000066195   ⟸   ENSRNOT00000072508
Ensembl Acc Id: ENSRNOP00000087897   ⟸   ENSRNOT00000100952
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0R8T8-F1-model_v2 AlphaFold M0R8T8 1-312 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-31557 BioCyc
Ensembl Genes ENSRNOG00000045969 Ensembl
  ENSRNOG00000049064 Ensembl
  ENSRNOG00000065153 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000089538 ENTREZGENE
Ensembl Transcript ENSRNOT00000100952 ENTREZGENE
  ENSRNOT00000100952.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405177 UniProtKB/TrEMBL
NCBI Gene 405177 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7g23c PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045969 RatGTEx
  ENSRNOG00000049064 RatGTEx
  ENSRNOG00000065153 RatGTEx
  ENSRNOG00000089538 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M0R8T8 ENTREZGENE, UniProtKB/TrEMBL
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7g23c  olfactory receptor family 7 subfamily G member 23C  Olr1135  olfactory receptor 1135  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1135  olfactory receptor 1135  LOC103693022  olfactory receptor 7G2-like  Data merged from RGD:9398762 737654 PROVISIONAL
2015-07-29 LOC103693022  olfactory receptor 7G2-like  LOC100911849  olfactory receptor 7G1-like  Data merged from RGD:6490708 737654 PROVISIONAL
2014-08-25 LOC103693022  olfactory receptor 7G2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911849  olfactory receptor 7G1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1135  olfactory receptor 1135   Olr1135_predicted  olfactory receptor 1135 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1135_predicted  olfactory receptor 1135 (predicted)      Symbol and Name status set to approved 70820 APPROVED