OR7G2 (olfactory receptor family 7 subfamily G member 2)

Gene: OR7G2 (olfactory receptor family 7 subfamily G member 2) Homo sapiens

Analyze

Symbol:

OR7G2

Name:

olfactory receptor family 7 subfamily G member 2

RGD ID:

1348157

HGNC Page

HGNC:8466

Description:

Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

olfactory receptor 19-13; olfactory receptor 7G2; olfactory receptor OR19-6; olfactory receptor, family 7, subfamily G, member 2; OR19-13; OR19-6; OST260

RGD Orthologs

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	9,100,407 - 9,107,475 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	9,100,407 - 9,107,475 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	9,211,083 - 9,218,151 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	9,073,945 - 9,074,982 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	9,073,944 - 9,074,982	NCBI
Celera	19	9,108,385 - 9,109,422 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	8,794,541 - 8,795,578 (-)	NCBI		HuRef
CHM1_1	19	9,212,647 - 9,213,684 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	9,226,573 - 9,233,642 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (IAGP)

genetic disease (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

4,4'-diaminodiphenylmethane (ISO)

alachlor (ISO)

benzo[a]pyrene (EXP)

bisphenol A (ISO)

epoxiconazole (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

detection of chemical stimulus involved in sensory perception of smell (IEA)

G protein-coupled receptor signaling pathway (IEA)

sensory perception of smell (IEA)

signal transduction (IBA,IEA)

Cellular Component

membrane (IEA)

plasma membrane (IBA,IEA,TAS)

Molecular Function

G protein-coupled receptor activity (IEA)

olfactory receptor activity (IBA,IEA)

Phenotype Annotations Click to see Annotation Detail View

Human Phenotype

Autism (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12213199	PMID:14983052	PMID:21873635

Genomics

Comparative Map Data

OR7G2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	9,100,407 - 9,107,475 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	9,100,407 - 9,107,475 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	9,211,083 - 9,218,151 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	9,073,945 - 9,074,982 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	9,073,944 - 9,074,982	NCBI
Celera	19	9,108,385 - 9,109,422 (-)	NCBI		Celera
Cytogenetic Map	19	p13.2	NCBI
HuRef	19	8,794,541 - 8,795,578 (-)	NCBI		HuRef
CHM1_1	19	9,212,647 - 9,213,684 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	9,226,573 - 9,233,642 (-)	NCBI		T2T-CHM13v2.0

Or7g27
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	19,249,755 - 19,250,696 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	19,247,753 - 19,253,014 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	19,338,459 - 19,339,400 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	19,336,457 - 19,341,718 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	19,142,903 - 19,143,844 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	19,088,864 - 19,089,802 (+)	NCBI		MGSCv36	mm8
Celera	9	16,617,564 - 16,618,505 (+)	NCBI		Celera
Cytogenetic Map	9	A2	NCBI
cM Map	9	7.27	NCBI

Or7g31
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	25,332,469 - 25,333,407 (-)	NCBI		GRCr8
mRatBN7.2	8	17,056,179 - 17,057,117 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	17,053,661 - 17,057,239 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	21,062,683 - 21,063,621 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	19,360,512 - 19,361,450 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	17,276,438 - 17,277,376 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	19,332,109 - 19,333,047 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	19,332,109 - 19,333,047 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	19,400,511 - 19,401,449 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	17,484,318 - 17,485,256 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	17,484,317 - 17,485,256 (-)	NCBI
Celera	8	18,471,387 - 18,472,325 (-)	NCBI		Celera
Cytogenetic Map	8	q13	NCBI

OR7G13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	51,634,215 - 51,635,174 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	51,497,790 - 51,498,728 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	52,156,210 - 52,157,148 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	52,156,210 - 52,157,148 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	51,362,921 - 51,363,859 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	51,788,667 - 51,789,605 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	52,030,336 - 52,031,274 (-)	NCBI		UU_Cfam_GSD_1.0

LOC110259632
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	2	67,202,992 - 67,203,963 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

Variants

Variants in OR7G2
20 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 19p13.3-13.2(chr19:1972245-9648879)x3	copy number gain	See cases [RCV000052879]	Chr19:1972245..9648879 [GRCh38] Chr19:1972244..9759555 [GRCh37] Chr19:1923244..9620555 [NCBI36] Chr19:19p13.3-13.2	pathogenic
GRCh38/hg38 19p13.3-13.2(chr19:4039158-9176125)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052881]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052881]\|See cases [RCV000052881]	Chr19:4039158..9176125 [GRCh38] Chr19:4039156..9286801 [GRCh37] Chr19:3990156..9147801 [NCBI36] Chr19:19p13.3-13.2	pathogenic
GRCh38/hg38 19p13.2-13.13(chr19:8831147-13331227)x3	copy number gain	See cases [RCV000052908]	Chr19:8831147..13331227 [GRCh38] Chr19:8941823..13442041 [GRCh37] Chr19:8802823..13303041 [NCBI36] Chr19:19p13.2-13.13	likely pathogenic
NM_001005193.1(OR7G2):c.870G>A (p.Arg290=)	single nucleotide variant	Malignant melanoma [RCV000063677]	Chr19:9102437 [GRCh38] Chr19:9213113 [GRCh37] Chr19:9074113 [NCBI36] Chr19:19p13.2	not provided
NM_001005193.2(OR7G2):c.833A>G (p.Tyr278Cys)	single nucleotide variant	Inborn genetic diseases [RCV003258166]	Chr19:9102411 [GRCh38] Chr19:9213087 [GRCh37] Chr19:19p13.2	uncertain significance
GRCh37/hg19 19p13.2(chr19:8661944-10104083)x1	copy number loss	Breast ductal adenocarcinoma [RCV000207085]	Chr19:8661944..10104083 [GRCh37] Chr19:19p13.2	uncertain significance
Single allele	complex	Breast ductal adenocarcinoma [RCV000207119]	Chr19:9001833..10085054 [GRCh37] Chr19:19p13.2	likely pathogenic\|uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3	copy number gain	See cases [RCV000511289]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic\|uncertain significance
GRCh37/hg19 19p13.3-13.2(chr19:3120160-9732820)x3	copy number gain	not provided [RCV000684096]	Chr19:3120160..9732820 [GRCh37] Chr19:19p13.3-13.2	pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)	copy number gain	See cases [RCV000512296]	Chr19:260912..58956888 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.2(chr19:8680063-9273676)x3	copy number gain	not provided [RCV001259374]	Chr19:8680063..9273676 [GRCh37] Chr19:19p13.2	uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3	copy number gain	not provided [RCV000752439]	Chr19:68029..59110290 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
Single allele	duplication	Autism [RCV000754212]	Chr19:7981357..10019383 [GRCh38] Chr19:19p13.2	likely pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3	copy number gain	not provided [RCV000752444]	Chr19:260912..59097160 [GRCh37] Chr19:19p13.3-q13.43	pathogenic
GRCh37/hg19 19p13.2(chr19:8905057-9606461)x1	copy number loss	not provided [RCV000740030]	Chr19:8905057..9606461 [GRCh37] Chr19:19p13.2	likely benign
NM_001005193.2(OR7G2):c.869A>G (p.Tyr290Cys)	single nucleotide variant	Inborn genetic diseases [RCV003249298]	Chr19:9102375 [GRCh38] Chr19:9213051 [GRCh37] Chr19:19p13.2	uncertain significance
GRCh37/hg19 19p13.2(chr19:8518395-10053298)x3	copy number gain	not provided [RCV001259373]	Chr19:8518395..10053298 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.20C>T (p.Thr7Ile)	single nucleotide variant	Inborn genetic diseases [RCV002773238]	Chr19:9103224 [GRCh38] Chr19:9213900 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.91T>C (p.Phe31Leu)	single nucleotide variant	Inborn genetic diseases [RCV002772360]	Chr19:9103153 [GRCh38] Chr19:9213829 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.620G>T (p.Gly207Val)	single nucleotide variant	Inborn genetic diseases [RCV002865371]	Chr19:9102624 [GRCh38] Chr19:9213300 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.74C>T (p.Pro25Leu)	single nucleotide variant	Inborn genetic diseases [RCV002683784]	Chr19:9103170 [GRCh38] Chr19:9213846 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.267T>G (p.Asn89Lys)	single nucleotide variant	Inborn genetic diseases [RCV002645011]	Chr19:9102977 [GRCh38] Chr19:9213653 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.563C>T (p.Thr188Ile)	single nucleotide variant	Inborn genetic diseases [RCV002873806]	Chr19:9102681 [GRCh38] Chr19:9213357 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.896G>A (p.Gly299Glu)	single nucleotide variant	Inborn genetic diseases [RCV002644583]	Chr19:9102348 [GRCh38] Chr19:9213024 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.359A>G (p.Tyr120Cys)	single nucleotide variant	Inborn genetic diseases [RCV002773809]	Chr19:9102885 [GRCh38] Chr19:9213561 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.882T>A (p.Asn294Lys)	single nucleotide variant	Inborn genetic diseases [RCV002689502]	Chr19:9102362 [GRCh38] Chr19:9213038 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.926C>T (p.Pro309Leu)	single nucleotide variant	Inborn genetic diseases [RCV002976972]	Chr19:9102318 [GRCh38] Chr19:9212994 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.604G>A (p.Ala202Thr)	single nucleotide variant	Inborn genetic diseases [RCV002823647]	Chr19:9102640 [GRCh38] Chr19:9213316 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.278C>T (p.Thr93Met)	single nucleotide variant	Inborn genetic diseases [RCV002805196]	Chr19:9102966 [GRCh38] Chr19:9213642 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.326G>A (p.Gly109Asp)	single nucleotide variant	Inborn genetic diseases [RCV002724580]	Chr19:9102918 [GRCh38] Chr19:9213594 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.20C>G (p.Thr7Arg)	single nucleotide variant	Inborn genetic diseases [RCV003367815]	Chr19:9103224 [GRCh38] Chr19:9213900 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.8C>T (p.Ala3Val)	single nucleotide variant	Inborn genetic diseases [RCV003175434]	Chr19:9103236 [GRCh38] Chr19:9213912 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.149T>C (p.Ile50Thr)	single nucleotide variant	Inborn genetic diseases [RCV003219548]	Chr19:9103095 [GRCh38] Chr19:9213771 [GRCh37] Chr19:19p13.2	uncertain significance
NM_001005193.2(OR7G2):c.611G>A (p.Cys204Tyr)	single nucleotide variant	Inborn genetic diseases [RCV003185440]	Chr19:9102633 [GRCh38] Chr19:9213309 [GRCh37] Chr19:19p13.2	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	170
Count of miRNA genes:	168
Interacting mature miRNAs:	169
Transcripts:	ENST00000305456
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

High

Medium

Low

Below cutoff

115

163

112

203

104

142

265

135

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001005193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB065927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC011464	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF399539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BK004268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS248316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290671	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KP290673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000305456 ⟹ ENSP00000303822

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	9,102,269 - 9,103,306 (-)	Ensembl

RefSeq Acc Id:

ENST00000641081 ⟹ ENSP00000492896

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	19	9,100,407 - 9,107,475 (-)	Ensembl

RefSeq Acc Id:

NM_001005193 ⟹ NP_001005193

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	19	9,100,407 - 9,107,475 (-)	NCBI
GRCh37	19	9,212,945 - 9,213,982 (-)	RGD
Build 36	19	9,073,945 - 9,074,982 (-)	NCBI Archive
Celera	19	9,108,385 - 9,109,422 (-)	RGD
HuRef	19	8,794,541 - 8,795,578 (-)	ENTREZGENE
CHM1_1	19	9,212,647 - 9,213,684 (-)	NCBI
T2T-CHM13v2.0	19	9,226,573 - 9,233,642 (-)	NCBI

Sequence:

show sequence

GGGATATAGACAGTGCAACAAGTCAGGCTGTAAGCACCTCACTGAACATCTCTTACCCAGCTCG
GAAGCTGCATCAGAACCTCCTTCCAGACATGATATTTTTGACCAGGACTCGAGTCTGTCTGCAC
TTCCTGAGGATAGATCATCCTCTGCAATATCCATATTCATCATCAACAGCATGGAAGCGAGAAA
CCAAACAGCTATTTCAAAATTCCTTCTCCTGGGACTGATAGAGGATCCGGAACTGCAGCCCGTC
CTTTTCAGCCTGTTCCTGTCCATGTACTTGGTCACCATCCTGGGGAACCTGCTCATCCTCTTGG
CTGTCATCTCTGACTCTCACCTCCACACCCCCATGTACTTCTTCCTCTCCAATCTCTCCTTTTT
GGACATTTGTTTAAGCACAACCACGATCCCAAAGATGCTGGTGAACATCCAAGCTCAGAATCGG
AGCATCACGTACTCAGGCTGCCTCACCCAGATCTGCTTTGTCTTGTTTTTTGCTGGCTTGGAAA
ATTGTCTCCTTGCAGCAATGGCCTATGACCGCTATGTGGCCATTTGTCACCCCCTTAGATACAC
AGTCATCATGAACCCCCGCCTCTGTGGCCTGCTGATTCTTCTCTCTCTGTTGACTAGTGTTGTG
AATGCCCTTCTTCTCAGCCTGATGGTGTTGAGGCTGTCCTTCTGCACAGACCTGGAAATCCCGC
TCTTCTTCTGTGAACTGGCTCAGGTCATCCAACTCACCTGTTCAGACACCCTCATCAATAACAT
CCTGATATATTTTGCAGCTTGCATATTTGGTGGTGTTCCTCTGTCTGGAATCATTTTGTCTTAC
ACTCAGATCACCTCCTGTGTTTTGAGAATGCCATCAGCAAGTGGAAAGCACAAAGCAGTTTCCA
CCTGTGGGTCTCACCTCTCCATTGTTCTCTTGTTCTATGGGGCAGGTTTGGGGGTGTACATTAG
TTCTGTGGTTACTGACTCACCTAGGAAGACTGCAGTGGCTTCAGTGATGTATTCTGTGTTCCCT
CAAATGGTGAACCCCTTTATCTATAGTCTGAGGAATAAGGACATGAAAGGAACCTTGAGGAAGT
TCATAGGGAGGATACCTTCTCTTCTGTGGTGTGCCATTTGCTTTGGATTCAGGTTTCTAGAGTA
AGTCAAAGTGACAGGATTCCTGGTGAGCTAGAATGCCTGACTCTTTGTTTTGTTTTGTTTTTTT
CTCTGAGATGGAGTCTTTCTCTGTCTCCCAGGCTGGAGTGCAATGGCACGACCTCGGCTCACTG
CAACTTCCGCCTCCGGGTTCAAGCCATCCTCCTGCCTCAGCCTCCTGAGTAGTGGGGATTACAG
GCGCCTGCCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGATAGAGTTTCACCATGTTGG
CCAGGCTGGTCTCAAACTCCTGACGTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGG
ATTACAGGCGTGAGACAATGCGCCCAGCCTGCCTGACTCTTTCATCACCAAGTTCTTCTAAAAT
GTCTAGATGACATAAAAGCCAACTACATTTCCACTCCGGCTTGAAATCTGACTTTGCTTTTTAT
GTCTGGATCTGTGATGATGGACATGTGATTTTAATTCTCTAGACTCAATTTCTTTGCTCAGGCC
ATAGACTCAGAGGCTGAGCCCAAGTTATTTATTTATTTATTTAGAGACAGAGTCTCGCTCTGTC
GGCCAGGCTGGAGTGCAGTGGTGTGATCTCGGCTCACTGTAATCTCTGCCTCCCAGGTTCAAGC
GATTCTCCCGCCTCAGCCTACTGAGTAGCTGGGACTACAGGTGCACGACACCACACCCGGCTAA
TTTTTGTACTTTTAGTAGAGGTGAGGTTTCATCATGCTGGCCAGGGTGGTCTCGATCTCCTGAC
CTTGTGATCCATTCGCCTCGGCCTCCCAAAGTTCTGGGATTACTGGGATTAGAGGCGTGAGCCA
CCGCTCCTGGCTAAGTGATTTTTTTTTAATGGATTAGTCTCAGAAGAAGAAAAGTTGTGGAAGG
TAGATAGTTCAGGAGGATAGGTCAGGAAAATGTATTTTTGGTTTTTTGTTTAGTTTAGGTTTTT
TGTTTTTTGTTTTGCTGAGACGGAGTCTTGCTCTGTCCACCAGGCTGGAGTGCAATGGCGCAAT
CTCGGCTAACTGCAACCTCCGCCTTCTGGGTTCAAGCGATTCTCCTACCTCAGGCTCCCAAGTA
GCTGGGCAGTTTTGTTTTTTGTTTCTTTTTTTCCATAGACAGGGTCTTGCTTTGTCACCTAGGC
TGGAATGCAATGACATGATCATAGCTCCCTGCAGCCCCAAACTCCAGGACTCCAGGGCTCAAAC
TCCAGGGACCCTCCTACCTCAGCCTCCTAGGAAGCTAGGACTCCAGGCATGCACCACCACGTCC
AGTGTGGGGTGTGGTGTAGAGATGGACTCTGGCTATGTTGCCCAGGTTGGTCTCAAAACCTAGG
TTCAAGTGATCCTCCTGCCATGGCCTCCCAAAGATCTGAGATTAGTGGTGAAGTCACTGTGCGC
TGCCAGGAAAAGGATTTAAGCGAGGTTGTTGTTATATCTGGAGACAAGCTTCCACCTTATTGCG
TATTTAGGGTCTTGTCAATTGCACCCCAGTGTAGACCTACAGTGGGTCAAGGGAGCTAAGTTTT
CATACCCAATTTAGTAACTACTGGGACCAGTCACTGGTAAACTATATTCTCCCTAGACAACATT
AGCATCTATTATACTCAGTTTTATCATCAAAAAATTAGCATGATTAGATTATCTTAGTGATTTG
AGATTATTGTGAGATATTTGAACTTCATAAGTGAGGATACCTTAGGTTCCAGTTTAAAGAATAG
GAGCCCTGGGCTGGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGG
TGGATCACTTGAGGTCAGGAGTTCAAAACTGGCCTGGCCCACGTGGTGAAACCCCATCTCTACT
AAAAATA

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Protein Sequences


Protein RefSeqs	NP_001005193	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK95024	(Get FASTA)	NCBI Sequence Viewer
	ALI87540	(Get FASTA)	NCBI Sequence Viewer
	ALI87662	(Get FASTA)	NCBI Sequence Viewer
	ALI87829	(Get FASTA)	NCBI Sequence Viewer
	ALI87830	(Get FASTA)	NCBI Sequence Viewer
	ALI87831	(Get FASTA)	NCBI Sequence Viewer
	BAC06142	(Get FASTA)	NCBI Sequence Viewer
	CAJ56681	(Get FASTA)	NCBI Sequence Viewer
	DAA04666	(Get FASTA)	NCBI Sequence Viewer
	EAW84007	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000492896
	ENSP00000492896.1
GenBank Protein	Q8NG99	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001005193 ⟸ NM_001005193

- UniProtKB:

Q8NG99 (UniProtKB/Swiss-Prot), Q6IFJ4 (UniProtKB/Swiss-Prot), Q96RA0 (UniProtKB/Swiss-Prot), A0A126GW43 (UniProtKB/TrEMBL), A0A126GWM3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPMQLLLTDFIIFSIRFIINSMEARNQTAISKFLLLGLIEDPELQPVLFSLFLSMYLVTILGNL
LILLAVISDSHLHTPMYFFLSNLSFLDICLSTTTIPKMLVNIQAQNRSITYSGCLTQICFVLFF
AGLENCLLAAMAYDRYVAICHPLRYTVIMNPRLCGLLILLSLLTSVVNALLLSLMVLRLSFCTD
LEIPLFFCELAQVIQLTCSDTLINNILIYFAACIFGGVPLSGIILSYTQITSCVLRMPSASGKH
KAVSTCGSHLSIVLLFYGAGLGVYISSVVTDSPRKTAVASVMYSVFPQMVNPFIYSLRNKDMKG
TLRKFIGRIPSLLWCAICFGFRFLE

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RefSeq Acc Id:

ENSP00000492896 ⟸ ENST00000641081

RefSeq Acc Id:

ENSP00000303822 ⟸ ENST00000305456

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8NG99-F1-model_v2	AlphaFold	Q8NG99	1-324	view protein structure

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:8466	AgrOrtholog
COSMIC	OR7G2	COSMIC
Ensembl Genes	ENSG00000170923	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000641081	ENTREZGENE
	ENST00000641081.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000170923	GTEx
HGNC ID	HGNC:8466	ENTREZGENE
Human Proteome Map	OR7G2	Human Proteome Map
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Olfact_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:390882	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	390882	ENTREZGENE
PANTHER	OLFACTORY RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORY RECEPTOR 7G2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA32738	PharmGKB
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OLFACTORYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A126GVU8_HUMAN	UniProtKB/TrEMBL
	A0A126GW43	ENTREZGENE, UniProtKB/TrEMBL
	A0A126GWM0_HUMAN	UniProtKB/TrEMBL
	A0A126GWM3	ENTREZGENE, UniProtKB/TrEMBL
	A0A126GWN7_HUMAN	UniProtKB/TrEMBL
	OR7G2_HUMAN	UniProtKB/Swiss-Prot
	Q6IFJ4	ENTREZGENE
	Q8NG99	ENTREZGENE
	Q96RA0	ENTREZGENE
UniProt Secondary	Q6IFJ4	UniProtKB/Swiss-Prot
	Q96RA0	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-15	OR7G2	olfactory receptor family 7 subfamily G member 2	OR7G2	olfactory receptor, family 7, subfamily G, member 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Human Phenotype Annotations - ClinVar