Alpk1 (alpha-kinase 1) - Rat Genome Database

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Gene: Alpk1 (alpha-kinase 1) Rattus norvegicus
Analyze
Symbol: Alpk1
Name: alpha-kinase 1
RGD ID: 1304613
Description: Predicted to enable monosaccharide binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cilium assembly; cytoplasmic pattern recognition receptor signaling pathway; and positive regulation of canonical NF-kappaB signal transduction. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytosol; microtubule cytoskeleton; and photoreceptor connecting cilium. Predicted to be active in cilium. Orthologous to human ALPK1 (alpha kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-protein kinase 1; LOC310879; RGD1304613; similar to lymphocyte alpha-kinase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82218,801,425 - 218,924,013 (-)NCBIGRCr8
mRatBN7.22216,126,939 - 216,247,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2216,128,825 - 216,247,157 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02231,997,360 - 232,117,471 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2231,996,088 - 232,117,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02251,345,268 - 251,462,165 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42224,934,194 - 224,989,819 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12224,888,846 - 224,988,527 (-)NCBI
Celera2208,443,568 - 208,559,107 (-)NCBICelera
Cytogenetic Map2q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alpk1Rataniridia  ISOALPK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital aniridiaClinVar 
Alpk1RatAxenfeld-Rieger syndrome type 1  ISOALPK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Axenfeld-Rieger syndrome type 1ClinVarPMID:25741868
Alpk1Ratgenetic disease  ISOALPK1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Alpk1RatRetinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Migraine Headache Syndrome  ISOALPK1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alpk1Ratdiabetes mellitus  ISOALPK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27542954
Alpk1RatDiabetic Nephropathies  ISOALPK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27542954
Alpk1Ratgout  ISOALPK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27542954
Alpk1Ratnephrosclerosis  ISOALPK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27542954
Alpk1RatWeight Loss  ISOALPK1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27542954
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alpk1RatRetinal Dystrophy, Optic Nerve Edema, Splenomegaly, Anhidrosis, and Migraine Headache Syndrome  ISOALPK1 (Homo sapiens)7240710 OMIM 

1 to 20 of 82 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Alpk1Rat(1->4)-beta-D-glucan multiple interactionsISOAlpk1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ALPK1 mRNACTDPMID:36331819
Alpk1Rat17beta-estradiol multiple interactionsISOALPK1 (Homo sapiens)6480464[Estradiol co-treated with Norethindrone Acetate] results in increased expression of ALPK1 mRNACTDPMID:22217510
Alpk1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOAlpk1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of ALPK1 mRNACTDPMID:21889950
Alpk1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ALPK1 mRNACTDPMID:33387578
Alpk1Rat2-hydroxypropanoic acid decreases expressionISOALPK1 (Homo sapiens)6480464Lactic Acid results in decreased expression of ALPK1 mRNACTDPMID:30851411
Alpk1Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOALPK1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ALPK1 mRNA more ...CTDPMID:28628672
Alpk1Rat4,4'-diaminodiphenylmethane increases expressionEXP 64804644 and 4'-diaminodiphenylmethane results in increased expression of ALPK1 mRNACTDPMID:30723492
Alpk1Rat4,4'-sulfonyldiphenol multiple interactionsISOALPK1 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of ALPK1 mRNACTDPMID:28628672
Alpk1Rat4-hydroxynon-2-enal decreases expressionISOAlpk1 (Mus musculus)64804644-hydroxy-2-nonenal results in decreased expression of ALPK1 mRNACTDPMID:19191707
Alpk1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of ALPK1 mRNACTDPMID:30047161
Alpk1Rat7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expressionISOAlpk1 (Mus musculus)6480464Uric Acid results in increased expression of ALPK1 mRNACTDPMID:27542954
Alpk1Rat7,9-dihydro-1H-purine-2,6,8(3H)-trione increases response to substanceISOALPK1 (Homo sapiens)6480464ALPK1 protein results in increased susceptibility to Uric AcidCTDPMID:27542954
Alpk1Rat7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expressionISOALPK1 (Homo sapiens)6480464Uric Acid results in increased expression of ALPK1 mRNACTDPMID:27542954
Alpk1Rat7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactionsISOALPK1 (Homo sapiens)6480464ALPK1 protein promotes the reaction [Uric Acid results in increased secretion of TGFB1 protein]CTDPMID:27542954
Alpk1Ratacrolein multiple interactionsISOALPK1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ALPK1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ALPK1 mRNACTDPMID:32699268
Alpk1Ratacrylamide increases expressionISOAlpk1 (Mus musculus)6480464Acrylamide results in increased expression of ALPK1 mRNACTDPMID:35032568
Alpk1Rataflatoxin B1 decreases expressionISOALPK1 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of ALPK1 mRNACTDPMID:21641981 and PMID:22100608
Alpk1Rataflatoxin B1 increases methylationISOALPK1 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of ALPK1 geneCTDPMID:27153756
Alpk1Ratall-trans-retinoic acid increases expressionISOALPK1 (Homo sapiens)6480464Tretinoin results in increased expression of ALPK1 mRNACTDPMID:33167477
Alpk1Ratalpha-pinene multiple interactionsISOALPK1 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ALPK1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ALPK1 mRNACTDPMID:32699268

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Cellular Component
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Molecular Function

  


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:23012479   PMID:28222186   PMID:28877472   PMID:30111836  



Alpk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82218,801,425 - 218,924,013 (-)NCBIGRCr8
mRatBN7.22216,126,939 - 216,247,180 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2216,128,825 - 216,247,157 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02231,997,360 - 232,117,471 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2231,996,088 - 232,117,134 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02251,345,268 - 251,462,165 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42224,934,194 - 224,989,819 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12224,888,846 - 224,988,527 (-)NCBI
Celera2208,443,568 - 208,559,107 (-)NCBICelera
Cytogenetic Map2q42NCBI
ALPK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384112,297,369 - 112,442,621 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4112,285,509 - 112,442,621 (+)EnsemblGRCh38hg38GRCh38
GRCh374113,218,525 - 113,363,777 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364113,437,948 - 113,583,223 (+)NCBINCBI36Build 36hg18NCBI36
Build 344113,656,455 - 113,720,433NCBI
Celera4110,512,576 - 110,657,856 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4108,950,042 - 109,095,428 (+)NCBIHuRef
CHM1_14113,195,311 - 113,340,525 (+)NCBICHM1_1
T2T-CHM13v2.04115,605,712 - 115,750,965 (+)NCBIT2T-CHM13v2.0
Alpk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393127,460,367 - 127,574,195 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3127,463,959 - 127,574,176 (-)EnsemblGRCm39 Ensembl
GRCm383127,666,718 - 127,780,547 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3127,670,310 - 127,780,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv373127,373,228 - 127,483,445 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363127,662,332 - 127,772,549 (-)NCBIMGSCv36mm8
Celera3134,160,957 - 134,282,674 (-)NCBICelera
Cytogenetic Map3G2NCBI
cM Map356.54NCBI
Alpk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545714,325,281 - 14,379,937 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545714,325,278 - 14,444,368 (-)NCBIChiLan1.0ChiLan1.0
ALPK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23110,372,767 - 110,517,166 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14110,666,192 - 110,813,772 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04104,786,721 - 104,931,981 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14115,349,826 - 115,495,026 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4115,430,258 - 115,495,026 (+)Ensemblpanpan1.1panPan2
ALPK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13232,135,110 - 32,270,732 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3232,136,738 - 32,267,264 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,763,410 - 9,897,996 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03232,358,805 - 32,493,869 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3232,364,919 - 32,493,694 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13232,341,883 - 32,476,840 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03232,102,803 - 32,237,847 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0327,622,218 - 7,758,515 (-)NCBIUU_Cfam_GSD_1.0
Alpk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053018,612,620 - 8,737,685 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365633,235,181 - 3,296,257 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365633,233,913 - 3,296,671 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALPK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8110,241,227 - 110,367,912 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18110,241,220 - 110,368,001 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28118,153,267 - 118,184,844 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ALPK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1760,096,755 - 60,233,569 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl760,202,204 - 60,236,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603738,857,444 - 38,994,232 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Alpk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248386,229,899 - 6,287,920 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248386,273,398 - 6,288,363 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Alpk1
895 total Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
2 224935826 224935827 C A snv HCR/1Mco (UMich), LCR/2Mco (UMich), HCR/2Mco (UMich), LCR/1Mco (UMich) View more Information


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
2 251347594 251347595 A C snv SDLEF7/Barth (UDEL) View more Information

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:38
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000030798
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 42 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat

1 to 10 of 42 rows
D2Rat291  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82218,830,334 - 218,830,507 (+)Marker Load Pipeline
mRatBN7.22216,155,848 - 216,156,021 (+)MAPPERmRatBN7.2
Rnor_6.02232,024,895 - 232,025,067NCBIRnor6.0
Rnor_5.02251,370,383 - 251,370,555UniSTSRnor5.0
RGSC_v3.42224,959,151 - 224,959,325RGDRGSC3.4
RGSC_v3.42224,959,152 - 224,959,324UniSTSRGSC3.4
RGSC_v3.12224,945,831 - 224,946,005RGD
Celera2208,470,906 - 208,471,078UniSTS
SHRSP x BN Map286.3798UniSTS
SHRSP x BN Map286.3798RGD
Cytogenetic Map2q42UniSTS
RH138670  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21783,113,432 - 83,113,679 (+)MAPPERmRatBN7.2
mRatBN7.22216,164,169 - 216,164,413 (+)MAPPERmRatBN7.2
Rnor_6.02232,033,215 - 232,033,458NCBIRnor6.0
Rnor_6.01787,490,477 - 87,490,723NCBIRnor6.0
Rnor_5.01789,181,425 - 89,181,671UniSTSRnor5.0
Rnor_5.02251,378,703 - 251,378,946UniSTSRnor5.0
RGSC_v3.42224,967,472 - 224,967,715UniSTSRGSC3.4
RGSC_v3.41794,592,933 - 94,593,179UniSTSRGSC3.4
Celera1782,379,911 - 82,380,157UniSTS
Celera2208,479,226 - 208,479,469UniSTS
Cytogenetic Map2q42UniSTS
Cytogenetic Map17q12.3UniSTS
Cytogenetic Map9q31UniSTS
RH139278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22216,129,254 - 216,129,480 (+)MAPPERmRatBN7.2
Rnor_6.02231,998,397 - 231,998,622NCBIRnor6.0
Rnor_5.02251,343,921 - 251,344,146UniSTSRnor5.0
RGSC_v3.42224,932,276 - 224,932,501UniSTSRGSC3.4
Celera2208,444,605 - 208,444,830UniSTS
RH 3.4 Map21547.1UniSTS
Cytogenetic Map2q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000030798   ⟹   ENSRNOP00000030809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2216,128,825 - 216,247,157 (-)Ensembl
Rnor_6.0 Ensembl2231,996,088 - 232,117,134 (-)Ensembl
RefSeq Acc Id: XM_017591342   ⟹   XP_017446831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82218,801,425 - 218,924,012 (-)NCBI
mRatBN7.22216,126,939 - 216,247,179 (-)NCBI
Rnor_6.02231,997,360 - 232,117,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104061   ⟹   XP_038959989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82218,801,425 - 218,924,013 (-)NCBI
mRatBN7.22216,126,939 - 216,247,179 (-)NCBI
RefSeq Acc Id: XM_039104062   ⟹   XP_038959990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82218,801,425 - 218,924,013 (-)NCBI
mRatBN7.22216,126,939 - 216,247,180 (-)NCBI
RefSeq Acc Id: XM_063282918   ⟹   XP_063138988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82218,801,425 - 218,924,009 (-)NCBI
RefSeq Acc Id: XM_227715   ⟹   XP_227715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82218,801,425 - 218,924,008 (-)NCBI
mRatBN7.22216,126,939 - 216,247,178 (-)NCBI
Rnor_6.02231,997,360 - 232,117,470 (-)NCBI
Rnor_5.02251,345,268 - 251,462,165 (-)NCBI
RGSC_v3.42224,934,194 - 224,989,819 (-)RGD
Sequence:
RefSeq Acc Id: XP_227715   ⟸   XM_227715
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017446831   ⟸   XM_017591342
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000030809   ⟸   ENSRNOT00000030798
RefSeq Acc Id: XP_038959990   ⟸   XM_039104062
- Peptide Label: isoform X2
- UniProtKB: A6HVL8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959989   ⟸   XM_039104061
- Peptide Label: isoform X1
- UniProtKB: A6HVL8 (UniProtKB/TrEMBL)
Alpha-type protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTA7-F1-model_v2 AlphaFold D3ZTA7 1-1231 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691748
Promoter ID:EPDNEW_R2266
Type:multiple initiation site
Name:Alpk1_1
Description:alpha-kinase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02232,117,142 - 232,117,202EPDNEW


1 to 19 of 19 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-51269 BioCyc
Ensembl Genes ENSRNOG00000022636 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030798.6 UniProtKB/TrEMBL
Gene3D-CATH MHCK/EF2 kinase UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
InterPro ALPK1 UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
NCBI Gene 310879 ENTREZGENE
PANTHER ALPHA-PROTEIN KINASE 1 UniProtKB/TrEMBL
  PTHR46747 UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
PhenoGen Alpk1 PhenoGen
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000022636 RatGTEx
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A6HVL8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZTA7 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Alpk1  alpha-kinase 1   Alpk1_predicted  alpha-kinase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Alpk1_predicted  alpha-kinase 1 (predicted)  RGD1304613_predicted  similar to lymphocyte alpha-kinase (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1304613_predicted  similar to lymphocyte alpha-kinase (predicted)  LOC310879_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC310879_predicted  similar to lymphocyte alpha-kinase (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL