FAM157C (family with sequence similarity 157 member C)

Gene: FAM157C (family with sequence similarity 157 member C) Homo sapiens

Analyze

Symbol:

FAM157C

Name:

family with sequence similarity 157 member C

RGD ID:

9587855

HGNC Page

HGNC:34081

Description:

INTERACTS WITH bisphenol A

Type:

ncrna (Ensembl: lncRNA)

RefSeq Status:

VALIDATED

Previously known as:

family with sequence similarity 157 member C (non-protein coding); LOC100132055; uncharacterized LOC100132055

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	90,102,264 - 90,177,606 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	90,102,261 - 90,178,344 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	90,168,672 - 90,244,014 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	16	q24.3	NCBI
HuRef	16	75,859,113 - 75,864,632 (+)	NCBI		HuRef
CHM1_1	16	91,579,122 - 91,584,675 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	96,188,555 - 96,265,713 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

bisphenol A (EXP)

References

Additional References at PubMed

PMID:14702039	PMID:15616553	PMID:16344560	PMID:36607351

Genomics

Variants

Variants in FAM157C
1 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	654
Count of miRNA genes:	497
Interacting mature miRNAs:	553
Transcripts:	ENST00000563357, ENST00000566898, ENST00000568070, ENST00000570230
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

209

233

Low

800

1037

663

294

1146

180

1515

379

906

166

968

1147

126

547

742

Below cutoff

1600

1668

1036

309

316

265

2747

1743

2648

203

472

440

654

1963

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NR_126161	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC133919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX459292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA670997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DB461851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENST00000563357

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,102,271 - 90,137,993 (+)	Ensembl

RefSeq Acc Id:

ENST00000566898

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,158,172 - 90,159,576 (+)	Ensembl

RefSeq Acc Id:

ENST00000568070

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,106,461 - 90,177,606 (+)	Ensembl

RefSeq Acc Id:

ENST00000570230

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,157,932 - 90,178,344 (+)	Ensembl

RefSeq Acc Id:

ENST00000660047

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,106,457 - 90,137,777 (+)	Ensembl

RefSeq Acc Id:

ENST00000660257

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,106,564 - 90,134,900 (+)	Ensembl

RefSeq Acc Id:

ENST00000660322

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,102,316 - 90,107,130 (+)	Ensembl

RefSeq Acc Id:

ENST00000663989

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,106,529 - 90,120,883 (+)	Ensembl

RefSeq Acc Id:

ENST00000667258

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,129,797 - 90,133,634 (+)	Ensembl

RefSeq Acc Id:

ENST00000691845

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	16	90,102,261 - 90,104,337 (+)	Ensembl

RefSeq Acc Id:

NR_126161

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	90,102,264 - 90,177,606 (+)	NCBI
CHM1_1	16	91,580,194 - 91,654,121 (+)	NCBI
T2T-CHM13v2.0	16	96,188,555 - 96,265,713 (+)	NCBI

Sequence:

show sequence

GACATTTACAAGAACTGGCGGCGGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGC
AGCAGCAACTGGATTTGCTTTTTCACCAGAGGATCCAGATTTCCCTGTGGCCTCGCAAACAAAA
AAGAAGGAAGACGGAGCAGCACAGTCATTCCTTTGTGAAAAAGGCATTCAGAGACGGGGTTTCA
CCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGCGATCCGCCCGCCTCGGCCTCCCAAAG
TGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCTTCAGCTGGTTTTTCAAAAGTCATGGCGT
GTAACTGTCCGAACAGTGAACTTCGGAGATCCACCGGAGGGGCGAGGCCACAGCTCGACCGCGA
GCACCTGAGCATCCTGCACCGCCTGCGACGGCCGTCAGGGGGCGCGATGCCGCCTCACAGAACC
TCAAGAGGCGCCCGGGTTCCGGCACAGACGGCCTGCGGCTCCAGGGGGCGGAACCGAGCCGTCT
CCTCAGGACCTACGCAGGAGGCGCCGTCATCCCTACAGGGACACCTGAGAGGGCCCAGCCTCCT
CCTCCTCAGGACCTACTCGGGAGACGCCGCTGGCTCTCTAGGAACACCTGGGGACCGTGGCCAG
GGACGACCCAGCCTCCTTCTCCTCAGCTCCTCAGGAACGACTGGGGAAGCTGTGGCTTCATGGT
CCCCGAGGCTGCCCGAGGAAAGACAGAGTCTCAACCAGGCTGGAGTGCAGTGGCGTGATCTCGG
CTCACTGCAACCTCCGCCTCCCAGGAGAATCACTTGAACTGGGAGATGGAGGTTGCAGTGAGCT
GAGATCGCACCAGTGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTTATAAAAGGAAAAA
AGAAAGAAAAGAAAAATTCCATATCTGAGTGTTTACTCCTGAGTTTTTGAGATTGTTATTAAGA
T

hide sequence

Protein Sequences


GenBank Protein	P0CG43	(Get FASTA)	NCBI Sequence Viewer

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0CG43-F1-model_v2	AlphaFold	P0CG43	1-387	view protein structure

Promoters

RGD ID:

15097015

Promoter ID:

EPDNEWNC_H1859

Type:

initiation region

Name:

FAM157C_1

Description:

family with sequence similarity 157 member C [Source:HGNCSymbol;Acc:HGNC:34081]

SO ACC ID:

SO:0000170

Source:

EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	90,102,264 - 90,102,324	EPDNEWNC

RGD ID:

15097019

Promoter ID:

EPDNEWNC_H1860

Type:

initiation region

Name:

FAM157C_2

Description:

family with sequence similarity 157 member C [Source:HGNCSymbol;Acc:HGNC:34081]

SO ACC ID:

SO:0000170

Source:

EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	16	90,106,448 - 90,106,508	EPDNEWNC

Additional Information

External Database Links

Database	Acc Id	Source(s)
COSMIC	FAM157C	COSMIC
Ensembl Genes	ENSG00000260528	Ensembl
GTEx	ENSG00000260528	GTEx
HGNC ID	HGNC:34081	ENTREZGENE
Human Proteome Map	FAM157C	Human Proteome Map
NCBI Gene	FAM157C	ENTREZGENE
PharmGKB	PA164719726	PharmGKB
RNAcentral	URS00007E49F7	RNACentral
UniProt	F157C_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-22	FAM157C	family with sequence similarity 157 member C		family with sequence similarity 157 member C (non-protein coding)	Symbol and/or name change	5135510	APPROVED
2017-03-21	FAM157C	family with sequence similarity 157 member C (non-protein coding)		family with sequence similarity 157 member C	Symbol and/or name change	5135510	APPROVED
2016-05-17	FAM157C	family with sequence similarity 157 member C	LOC100132055	uncharacterized LOC100132055	Data merged from RGD:2303665	737654	PROVISIONAL
2015-11-24	FAM157C	family with sequence similarity 157 member C		family with sequence similarity 157, member C	Symbol and/or name change	5135510	APPROVED
2013-04-23	LOC100132055	uncharacterized LOC100132055		putative protein FAM157C	Symbol and/or name change	5135510	APPROVED
2013-04-02	LOC100132055	putative protein FAM157C	FAM157C	family with sequence similarity 157, member C	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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