TGFB2-AS1 (TGFB2 antisense RNA 1 (head to head)) - Rat Genome Database

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Gene: TGFB2-AS1 (TGFB2 antisense RNA 1 (head to head)) Homo sapiens
Analyze
Symbol: TGFB2-AS1
Name: TGFB2 antisense RNA 1 (head to head)
RGD ID: 9586109
HGNC Page HGNC:50628
Description: ASSOCIATED WITH Loeys-Dietz syndrome 4; Usher syndrome; INTERACTS WITH aristolochic acid A; bisphenol A; sodium arsenite
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,344,196 - 218,345,678 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,344,145 - 218,347,866 (-)EnsemblGRCh38hg38GRCh38
GRCh371218,517,538 - 218,519,020 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361216,584,177 - 216,586,375 (-)NCBINCBI36Build 36hg18NCBI36
Celera1191,734,015 - 191,736,209 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1189,185,708 - 189,187,186 (-)NCBIHuRef
CHM1_11219,789,890 - 219,791,368 (-)NCBICHM1_1
T2T-CHM13v2.01217,578,960 - 217,580,442 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TGFB2-AS1HumanLoeys-Dietz syndrome 4  IAGPRGD:115962948554872ClinVar Annotator: match by term: Loeys-Dietz syndrome 4ClinVarPMID:25741868
TGFB2-AS1HumanLoeys-Dietz syndrome 4  IAGPRGD:11655032|RGD:11661757|RGD:14729133|RGD:28889418|RGD:288894228554872ClinVar Annotator: match by term: Loeys-Dietz syndrome 4ClinVar 
TGFB2-AS1HumanUsher syndrome  IAGPRGD:134354448554872ClinVar Annotator: match by term: Usher syndromeClinVarPMID:28041643


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TGFB2-AS1Humanaristolochic acid A decreases expressionEXP 6480464aristolochic acid I results in decreased expression of TGFB2-AS1 mRNACTDPMID:33212167
TGFB2-AS1Humanbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of TGFB2-AS1 mRNACTDPMID:31715268
TGFB2-AS1Humansodium arsenite increases expressionEXP 6480464sodium arsenite results in increased expression of TGFB2-AS1 mRNACTDPMID:29301061
TGFB2-AS1Humansodium arsenite decreases expressionEXP 6480464sodium arsenite results in decreased expression of TGFB2-AS1 mRNACTDPMID:34032870
TGFB2-AS1Humantriclosan decreases expressionEXP 6480464Triclosan results in decreased expression of TGFB2-AS1 mRNACTDPMID:30510588

PMID:27816668   PMID:31533040   PMID:32423825   PMID:36126099  



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Variants in TGFB2-AS1
7 total Variants

1 to 10 of 25 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 1q32.2-44(chr1:209963625-248918469)x3 copy number gain See cases [RCV000134979] Chr1:209963625..248918469 [GRCh38]
Chr1:210136970..249212668 [GRCh37]
Chr1:208203593..247179291 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q41(chr1:217558925-218732002)x3 copy number gain See cases [RCV000142313] Chr1:217558925..218732002 [GRCh38]
Chr1:217732267..218905344 [GRCh37]
Chr1:215798890..216971967 [NCBI36]
Chr1:1q41		 uncertain significance
GRCh38/hg38 1q32.1-42.12(chr1:204764914-225408698)x3 copy number gain See cases [RCV000142054] Chr1:204764914..225408698 [GRCh38]
Chr1:204734042..225596400 [GRCh37]
Chr1:203000665..223663023 [NCBI36]
Chr1:1q32.1-42.12		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:207346642-248930485)x3 copy number gain See cases [RCV000143727] Chr1:207346642..248930485 [GRCh38]
Chr1:207519987..249224684 [GRCh37]
Chr1:205586610..247191307 [NCBI36]
Chr1:1q32.2-44		 pathogenic
GRCh38/hg38 1q41(chr1:215206760-222004068)x1 copy number loss See cases [RCV000148255] Chr1:215206760..222004068 [GRCh38]
Chr1:215380103..222177410 [GRCh37]
Chr1:213446726..220244033 [NCBI36]
Chr1:1q41		 pathogenic
GRCh38/hg38 1q32.3-44(chr1:214023812-248918469)x3 copy number gain See cases [RCV000050981] Chr1:214023812..248918469 [GRCh38]
Chr1:214197155..249212668 [GRCh37]
Chr1:212263778..247179291 [NCBI36]
Chr1:1q32.3-44		 pathogenic
GRCh38/hg38 1q41(chr1:218321722-218961624)x1 copy number loss See cases [RCV000050854] Chr1:218321722..218961624 [GRCh38]
Chr1:218495064..219134966 [GRCh37]
Chr1:216561687..217201589 [NCBI36]
Chr1:1q41		 uncertain significance
GRCh38/hg38 1q41(chr1:215206760-222004068)x1 copy number loss See cases [RCV000050298] Chr1:215206760..222004068 [GRCh38]
Chr1:215380103..222177410 [GRCh37]
Chr1:213446726..220244033 [NCBI36]
Chr1:1q41		 pathogenic
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3 copy number gain See cases [RCV000051857] Chr1:187143981..224299417 [GRCh38]
Chr1:187113113..224487119 [GRCh37]
Chr1:185379736..222553742 [NCBI36]
Chr1:1q31.1-42.11		 pathogenic
GRCh38/hg38 1q32.2-44(chr1:209646207-248931113)x3 copy number gain See cases [RCV000051861] Chr1:209646207..248931113 [GRCh38]
Chr1:209819552..249225312 [GRCh37]
Chr1:207886175..247191935 [NCBI36]
Chr1:1q32.2-44		 pathogenic
1 to 10 of 25 rows

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:78
Interacting mature miRNAs:78
Transcripts:ENST00000414452
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
661 1661 2272 1831 4158 1251 1874 2 378 459 225 1428 4693 3870 46 3522 738 1580 1380 171 1



Ensembl Acc Id: ENST00000414452
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,190 - 218,346,050 (-)Ensembl
Ensembl Acc Id: ENST00000687392
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,345,987 (-)Ensembl
Ensembl Acc Id: ENST00000689961
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,042 (-)Ensembl
Ensembl Acc Id: ENST00000691401
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,018 (-)Ensembl
Ensembl Acc Id: ENST00000702858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,145 - 218,346,027 (-)Ensembl
Ensembl Acc Id: ENST00000774588
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,347,866 (-)Ensembl
Ensembl Acc Id: ENST00000774589
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,190 - 218,347,659 (-)Ensembl
Ensembl Acc Id: ENST00000774590
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,208 - 218,347,662 (-)Ensembl
Ensembl Acc Id: ENST00000774591
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,354 (-)Ensembl
Ensembl Acc Id: ENST00000774592
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,352 (-)Ensembl
Ensembl Acc Id: ENST00000774593
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,352 (-)Ensembl
Ensembl Acc Id: ENST00000774594
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,351 (-)Ensembl
Ensembl Acc Id: ENST00000774595
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,192 - 218,346,345 (-)Ensembl
Ensembl Acc Id: ENST00000774596
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,345 (-)Ensembl
Ensembl Acc Id: ENST00000774597
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,198 - 218,346,346 (-)Ensembl
Ensembl Acc Id: ENST00000774598
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,203 - 218,346,351 (-)Ensembl
Ensembl Acc Id: ENST00000774599
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,205 - 218,346,345 (-)Ensembl
Ensembl Acc Id: ENST00000774600
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,208 - 218,346,345 (-)Ensembl
Ensembl Acc Id: ENST00000774601
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,210 - 218,346,345 (-)Ensembl
Ensembl Acc Id: ENST00000774602
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,210 - 218,346,342 (-)Ensembl
Ensembl Acc Id: ENST00000774603
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,210 - 218,346,337 (-)Ensembl
Ensembl Acc Id: ENST00000774604
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,191 (-)Ensembl
Ensembl Acc Id: ENST00000774605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,195 - 218,346,042 (-)Ensembl
Ensembl Acc Id: ENST00000774606
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,210 - 218,346,039 (-)Ensembl
Ensembl Acc Id: ENST00000774607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,207 - 218,346,013 (-)Ensembl
Ensembl Acc Id: ENST00000774608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,205 - 218,345,817 (-)Ensembl
Ensembl Acc Id: ENST00000774611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,203 - 218,345,418 (-)Ensembl
Ensembl Acc Id: ENST00000774612
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1218,344,199 - 218,345,414 (-)Ensembl
RefSeq Acc Id: NR_046268
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381218,344,196 - 218,345,678 (-)NCBI
HuRef1189,185,708 - 189,187,186 (-)NCBI
CHM1_11219,789,890 - 219,791,368 (-)NCBI
T2T-CHM13v2.01217,578,960 - 217,580,442 (-)NCBI
Sequence:


1 to 12 of 12 rows
Database
Acc Id
Source(s)
COSMIC TGFB2-AS1 COSMIC
Ensembl Genes ENSG00000232480 Ensembl
GTEx ENSG00000232480 GTEx
HGNC ID HGNC:50628 ENTREZGENE
Human Proteome Map TGFB2-AS1 Human Proteome Map
NCBI Gene TGFB2-AS1 ENTREZGENE
RNAcentral URS0000126BEF RNACentral
  URS00022AF085 RNACentral
  URS00022AFA1A RNACentral
  URS00022B03F0 RNACentral
  URS00025E5E3E RNACentral
  URS00025F2B96 RNACentral
1 to 12 of 12 rows