Dsn1 (DSN1 component of MIS12 kinetochore complex) - Rat Genome Database

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Gene: Dsn1 (DSN1 component of MIS12 kinetochore complex) Chinchilla lanigera
Analyze
Symbol: Dsn1
Name: DSN1 component of MIS12 kinetochore complex
RGD ID: 8958786
Description: INVOLVED IN skeletal muscle satellite cell proliferation (ortholog); ASSOCIATED WITH colorectal cancer (ortholog); focal epilepsy (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); fibrillar center (ortholog); kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DSN1 homolog, MIS12 kinetochore complex component; DSN1, MIS12 kinetochore complex component; kinetochore-associated protein DSN1 homolog
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dsn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBIChiLan1.0ChiLan1.0
DSN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382036,751,795 - 36,773,763 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2036,751,791 - 36,773,818 (-)EnsemblGRCh38hg38GRCh38
GRCh372035,380,198 - 35,402,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362034,813,862 - 34,835,563 (-)NCBINCBI36Build 36hg18NCBI36
Build 342034,813,861 - 34,835,563NCBI
Celera2032,087,712 - 32,109,752 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,116,840 - 32,138,884 (-)NCBIHuRef
CHM1_12035,281,951 - 35,303,991 (-)NCBICHM1_1
T2T-CHM13v2.02038,476,075 - 38,498,047 (-)NCBIT2T-CHM13v2.0
Dsn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392156,836,982 - 156,848,995 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2156,837,185 - 156,849,074 (-)EnsemblGRCm39 Ensembl
GRCm382156,995,062 - 157,007,075 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2156,995,265 - 157,007,154 (-)EnsemblGRCm38mm10GRCm38
MGSCv372156,820,798 - 156,832,811 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362156,686,706 - 156,698,516 (-)NCBIMGSCv36mm8
Celera2162,930,851 - 162,942,859 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.89NCBI
Dsn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,072,775 - 166,089,029 (-)NCBIGRCr8
mRatBN7.23145,652,741 - 145,668,025 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3145,652,737 - 145,665,856 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3149,479,403 - 149,491,260 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03157,977,892 - 157,989,744 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03155,717,666 - 155,729,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03153,101,020 - 153,115,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3153,101,036 - 153,114,520 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,598,732 - 158,611,011 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43147,575,110 - 147,586,968 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3144,362,164 - 144,374,022 (-)NCBICelera
Cytogenetic Map3q42NCBI
DSN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22142,488,112 - 42,510,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12042,481,210 - 42,503,230 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,083,222 - 33,105,563 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,202,053 - 34,223,735 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,202,053 - 34,223,729 (-)Ensemblpanpan1.1panPan2
DSN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12425,506,954 - 25,523,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2425,507,667 - 25,523,155 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,152,621 - 25,168,599 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,204,555 - 26,220,531 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,204,405 - 26,220,288 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12425,482,726 - 25,498,705 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02425,582,494 - 25,598,740 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,072,339 - 26,088,326 (-)NCBIUU_Cfam_GSD_1.0
Dsn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640174,411,961 - 174,426,798 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365614,322,675 - 4,337,506 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365614,322,709 - 4,337,405 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1739,990,624 - 40,017,365 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11739,992,769 - 40,017,388 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21745,435,426 - 45,457,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1257,511,171 - 57,525,241 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl257,511,366 - 57,527,088 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666054533,022 - 551,858 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dsn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248422,738,734 - 2,760,783 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248422,738,739 - 2,762,968 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005384734   ⟹   XP_005384791
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005384736   ⟹   XP_005384793
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514023   ⟹   XP_013369477
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542224,876,340 - 24,896,435 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005384791 (Get FASTA)   NCBI Sequence Viewer  
  XP_005384793 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369477 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000003658.1
  ENSCLAP00000023626
  ENSCLAP00000023626.1
RefSeq Acc Id: XP_005384791   ⟸   XM_005384734
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005384793   ⟸   XM_005384736
- Peptide Label: isoform X3
- UniProtKB: A0A8C2YJP3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369477   ⟸   XM_013514023
- Peptide Label: isoform X2
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002606 UniProtKB/TrEMBL
  ENSCLAG00000016204 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000003732.1 UniProtKB/TrEMBL
  ENSCLAT00000023850 ENTREZGENE
  ENSCLAT00000023850.1 UniProtKB/TrEMBL
InterPro Dsn1/Mis13 UniProtKB/TrEMBL
NCBI Gene Dsn1 ENTREZGENE
PANTHER KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG UniProtKB/TrEMBL
  PTHR14778 UniProtKB/TrEMBL
Pfam MIS13 UniProtKB/TrEMBL
UniProt A0A8C2W914_CHILA UniProtKB/TrEMBL
  A0A8C2YJP3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Dsn1  DSN1 component of MIS12 kinetochore complex    DSN1 homolog, MIS12 kinetochore complex component  Symbol and/or name change 5135510 APPROVED
2015-08-25 Dsn1  DSN1 homolog, MIS12 kinetochore complex component    DSN1, MIS12 kinetochore complex component  Symbol and/or name change 5135510 APPROVED