Kiz (kizuna centrosomal protein) - Rat Genome Database

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Gene: Kiz (kizuna centrosomal protein) Chinchilla lanigera
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Symbol: Kiz
Name: kizuna centrosomal protein
RGD ID: 8911633
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN spindle organization (ortholog); ASSOCIATED WITH familial hyperinsulinemic hypoglycemia 1 (ortholog); fundus dystrophy (ortholog); retinitis pigmentosa (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: centrosomal protein kizuna; Plk1s1; polo-like kinase 1 substrate 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,991,630 - 29,078,884 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541528,991,766 - 29,078,796 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centrosome  (ISO)
cytoplasm  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Kiz
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,991,630 - 29,078,884 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541528,991,766 - 29,078,796 (+)NCBIChiLan1.0ChiLan1.0
KIZ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382021,125,975 - 21,246,622 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2021,125,983 - 21,246,622 (+)EnsemblGRCh38hg38GRCh38
GRCh372021,106,616 - 21,227,260 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362021,054,646 - 21,175,260 (+)NCBINCBI36Build 36hg18NCBI36
Build 342021,054,694 - 21,175,256NCBI
Celera2021,183,174 - 21,303,815 (+)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2021,071,704 - 21,192,358 (+)NCBIHuRef
CHM1_12021,107,363 - 21,227,996 (+)NCBICHM1_1
T2T-CHM13v2.02021,186,759 - 21,305,970 (+)NCBIT2T-CHM13v2.0
Kiz
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392146,697,743 - 146,812,018 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2146,697,784 - 146,812,017 (+)EnsemblGRCm39 Ensembl
GRCm382146,855,825 - 146,970,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2146,855,864 - 146,970,097 (+)EnsemblGRCm38mm10GRCm38
MGSCv372146,681,625 - 146,795,825 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362146,547,328 - 146,661,530 (+)NCBIMGSCv36mm8
Celera2148,106,851 - 148,232,298 (+)NCBICelera
Cytogenetic Map2G2NCBI
cM Map272.63NCBI
Kiz
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,730,873 - 154,838,410 (+)NCBIGRCr8
mRatBN7.23134,277,631 - 134,385,260 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3134,277,687 - 134,385,190 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3138,189,970 - 138,298,151 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03146,774,065 - 146,882,251 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03144,477,231 - 144,585,406 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03141,067,981 - 141,173,738 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3141,068,023 - 141,173,858 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03147,486,119 - 147,591,815 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43135,488,158 - 135,598,982 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13135,393,580 - 135,504,601 (+)NCBI
Celera3133,139,893 - 133,248,521 (+)NCBICelera
Cytogenetic Map3q41NCBI
KIZ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22122,014,744 - 22,135,698 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12022,011,575 - 22,132,534 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02021,083,709 - 21,204,456 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12021,045,145 - 21,165,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2021,045,120 - 21,165,789 (+)Ensemblpanpan1.1panPan2
KIZ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,174,905 - 2,305,860 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,174,905 - 2,305,811 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha242,203,132 - 2,334,123 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0242,582,201 - 2,713,206 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl242,582,201 - 2,713,569 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1242,179,382 - 2,310,248 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0242,282,203 - 2,413,181 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0242,559,220 - 2,691,071 (-)NCBIUU_Cfam_GSD_1.0
Kiz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640150,767,892 - 150,890,265 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366204,185,898 - 4,310,738 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366204,188,350 - 4,310,708 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIZ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1728,980,328 - 29,082,392 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11728,975,131 - 29,082,397 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,928,130 - 33,035,561 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KIZ
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1250,113,210 - 50,235,910 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660784,904,218 - 5,034,234 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kiz
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474121,566,085 - 21,669,837 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474121,566,094 - 21,668,613 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000018511   ⟹   ENSCLAP00000018332
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541528,991,630 - 29,078,884 (+)Ensembl
RefSeq Acc Id: XM_005380949   ⟹   XP_005381006
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541528,991,766 - 29,078,796 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005380950   ⟹   XP_005381007
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541528,992,304 - 29,078,796 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512366   ⟹   XP_013367820
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541528,999,254 - 29,078,796 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381006 (Get FASTA)   NCBI Sequence Viewer  
  XP_005381007 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367820 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018332
  ENSCLAP00000018332.1
RefSeq Acc Id: XP_005381006   ⟸   XM_005380949
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VW09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005381007   ⟸   XM_005380950
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013367820   ⟸   XM_013512366
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000018332   ⟸   ENSCLAT00000018511


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012565 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018511 ENTREZGENE
  ENSCLAT00000018511.1 UniProtKB/TrEMBL
InterPro Centrosomal_kizuma UniProtKB/TrEMBL
NCBI Gene Plk1s1 ENTREZGENE
PANTHER CENTROSOMAL PROTEIN KIZUNA UniProtKB/TrEMBL
  PTHR16299 UniProtKB/TrEMBL
UniProt A0A8C2VW09 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Kiz  kizuna centrosomal protein  Plk1s1  polo-like kinase 1 substrate 1  Symbol and/or name change 5135510 APPROVED