Dlx3 (distal-less homeobox 3) - Rat Genome Database

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Gene: Dlx3 (distal-less homeobox 3) Chinchilla lanigera
Analyze
Symbol: Dlx3
Name: distal-less homeobox 3
RGD ID: 8845043
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN blood vessel development (ortholog); BMP signaling pathway (ortholog); gene expression (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 1B (ortholog); amelogenesis imperfecta type 4 (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein DLX-3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,635,025 - 11,640,094 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,635,027 - 11,640,091 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dlx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,635,025 - 11,640,094 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,635,027 - 11,640,091 (+)NCBIChiLan1.0ChiLan1.0
DLX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381749,990,005 - 49,995,224 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1749,990,005 - 49,995,224 (-)EnsemblGRCh38hg38GRCh38
GRCh371748,067,369 - 48,072,588 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,422,368 - 45,427,587 (-)NCBINCBI36Build 36hg18NCBI36
Build 341745,422,369 - 45,427,587NCBI
Celera1744,522,674 - 44,527,893 (-)NCBICelera
Cytogenetic Map17q21.33NCBI
HuRef1743,432,201 - 43,437,420 (-)NCBIHuRef
CHM1_11748,131,324 - 48,136,543 (-)NCBICHM1_1
T2T-CHM13v2.01750,853,145 - 50,858,364 (-)NCBIT2T-CHM13v2.0
Dlx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391195,010,943 - 95,016,122 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1195,010,945 - 95,016,122 (+)EnsemblGRCm39 Ensembl
GRCm381195,120,117 - 95,125,296 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,120,119 - 95,125,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,981,431 - 94,986,607 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,927,281 - 94,941,375 (+)NCBIMGSCv36mm8
Celera11104,731,026 - 104,736,202 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.01NCBI
Dlx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81080,561,335 - 80,566,730 (+)NCBIGRCr8
mRatBN7.21080,064,489 - 80,069,891 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1080,064,489 - 80,069,872 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1085,012,728 - 85,018,082 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01084,510,795 - 84,516,153 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01079,904,811 - 79,910,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01082,937,971 - 82,943,367 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,937,971 - 82,943,348 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,748,717 - 82,754,113 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,802,169 - 83,807,565 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11083,816,537 - 83,821,901 (+)NCBI
Celera1078,837,978 - 78,843,374 (+)NCBICelera
Cytogenetic Map10q26NCBI
DLX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21966,174,243 - 66,179,497 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11770,980,766 - 70,986,020 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01744,076,437 - 44,081,690 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11748,950,467 - 48,955,848 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1748,950,474 - 48,955,848 (-)Ensemblpanpan1.1panPan2
DLX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,018,101 - 26,022,964 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,017,689 - 26,022,736 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,411,246 - 25,416,061 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0926,812,590 - 26,817,409 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl926,812,181 - 26,817,445 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1925,580,439 - 25,585,227 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0925,839,568 - 25,844,414 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0925,969,011 - 25,973,822 (-)NCBIUU_Cfam_GSD_1.0
Dlx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,444,024 - 25,449,328 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649011,625,862 - 11,631,131 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649011,625,862 - 11,630,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,177,903 - 26,183,157 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,177,896 - 26,183,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,192,842 - 26,198,116 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DLX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11643,339,733 - 43,345,599 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1643,340,576 - 43,344,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607714,056,290 - 14,061,725 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dlx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247956,015,523 - 6,018,684 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247956,014,044 - 6,018,819 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000020111   ⟹   ENSCLAP00000019918
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545111,635,025 - 11,640,094 (+)Ensembl
RefSeq Acc Id: XM_005394184   ⟹   XP_005394241
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545111,635,027 - 11,640,091 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394241 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019918
  ENSCLAP00000019918.1
RefSeq Acc Id: XP_005394241   ⟸   XM_005394184
- UniProtKB: A0A8C2VWK6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000019918   ⟸   ENSCLAT00000020111
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013654 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000020111 ENTREZGENE
  ENSCLAT00000020111.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Distal-less_Homeobox_TF UniProtKB/TrEMBL
  Distal-less_N UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/TrEMBL
  HTH_motif UniProtKB/TrEMBL
NCBI Gene Dlx3 ENTREZGENE
PANTHER HOMEOBOX PROTEIN UniProtKB/TrEMBL
  HOMEOBOX PROTEIN DLX-3 UniProtKB/TrEMBL
Pfam DLL_N UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
PRINTS HOMEOBOX UniProtKB/TrEMBL
  HTHREPRESSR UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C2VWK6 ENTREZGENE, UniProtKB/TrEMBL