Irf2bp2 (interferon regulatory factor 2 binding protein 2) - Rat Genome Database

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Gene: Irf2bp2 (interferon regulatory factor 2 binding protein 2) Chinchilla lanigera
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Symbol: Irf2bp2
Name: interferon regulatory factor 2 binding protein 2
RGD ID: 8783948
Description: ENCODES a protein that exhibits transcription corepressor activity (ortholog); INVOLVED IN immature B cell differentiation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); common variable immunodeficiency 14 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interferon regulatory factor 2-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554924,889,878 - 4,894,325 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554924,889,878 - 4,895,508 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillacommon variable immunodeficiency 14  ISOIRF2BP2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:24033266 more ...
Irf2bp2Chinchillagastrointestinal stromal tumor  ISOIRF2BP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:28492532
Irf2bp2ChinchillaImmune Deficiency, Familial Variable  ISOIRF2BP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Immune deficiency and familial variableClinVarPMID:25741868
Irf2bp2Chinchillaparathyroid carcinoma  ISOIRF2BP2 (Homo sapiens)8554872ClinVar Annotator: match by term: Parathyroid carcinomaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillaacute promyelocytic leukemia  ISOIRF2BP2 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:25583766
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillacommon variable immunodeficiency 14  ISOIRF2BP2 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillaimmature B cell differentiation involved_inISOIRF2BP2 (Homo sapiens)9068941 PMID:27016798UniProtPMID:27016798
Irf2bp2Chinchillanegative regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOIRF2BP2 (Homo sapiens)9068941 PMID:12799427MGIPMID:12799427

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillanucleoplasm located_inISOIRF2BP2 (Homo sapiens)9068941 HPAGO_REF:0000052
Irf2bp2Chinchillanucleus located_inISOIRF2BP2 (Homo sapiens)9068941 PMID:12799427MGIPMID:12799427

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Irf2bp2Chinchillatranscription corepressor activity enablesISOIRF2BP2 (Homo sapiens)9068941 PMID:12799427MGIPMID:12799427


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:30032202  



Irf2bp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554924,889,878 - 4,894,325 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554924,889,878 - 4,895,508 (-)NCBIChiLan1.0ChiLan1.0
IRF2BP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381234,604,269 - 234,610,178 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1234,602,300 - 234,610,178 (-)EnsemblGRCh38hg38GRCh38
GRCh371234,740,015 - 234,745,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361232,806,638 - 232,811,894 (-)NCBINCBI36Build 36hg18NCBI36
Celera1208,010,244 - 208,015,502 (-)NCBICelera
Cytogenetic Map1q42.3NCBI
HuRef1205,232,981 - 205,238,075 (-)NCBIHuRef
CHM1_11236,012,268 - 236,017,524 (-)NCBICHM1_1
T2T-CHM13v2.01233,994,665 - 234,000,583 (-)NCBIT2T-CHM13v2.0
Irf2bp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398127,315,035 - 127,320,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8127,315,035 - 127,320,725 (-)EnsemblGRCm39 Ensembl
GRCm388126,588,296 - 126,593,986 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8126,588,296 - 126,593,986 (-)EnsemblGRCm38mm10GRCm38
MGSCv378129,112,196 - 129,117,336 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368129,474,384 - 129,479,526 (-)NCBIMGSCv36mm8
Celera8130,897,219 - 130,902,103 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map874.57NCBI
Irf2bp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81971,456,689 - 71,462,368 (-)NCBIGRCr8
mRatBN7.21954,559,417 - 54,565,096 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1954,560,128 - 54,566,642 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1961,345,743 - 61,351,427 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01962,205,652 - 62,211,336 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01964,291,822 - 64,297,510 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01959,497,021 - 59,502,298 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1959,499,876 - 59,502,161 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01970,169,829 - 70,175,053 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1953,912,064 - 53,916,754 (-)NCBICelera
Cytogenetic Map19q12NCBI
IRF2BP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2114,590,955 - 14,596,867 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1114,801,899 - 14,807,596 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,143,516 - 210,148,878 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,163,887 - 215,168,637 (-)NCBIpanpan1.1PanPan1.1panPan2
IRF2BP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.145,242,225 - 5,249,371 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl45,244,869 - 5,247,247 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha45,226,563 - 5,232,031 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.045,264,484 - 5,269,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl45,264,541 - 5,266,921 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.145,277,144 - 5,282,623 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.045,393,163 - 5,398,624 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.045,617,176 - 5,622,660 (+)NCBIUU_Cfam_GSD_1.0
Irf2bp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934441,490,015 - 41,493,458 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648417,655,241 - 17,659,553 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648417,653,519 - 17,661,811 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF2BP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1456,545,685 - 56,551,125 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11456,545,792 - 56,551,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IRF2BP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12571,774,447 - 71,779,759 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2571,773,588 - 71,779,835 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605573,799,101 - 73,804,664 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irf2bp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477515,482,630 - 15,484,824 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477515,479,808 - 15,484,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Ensembl Acc Id: ENSCLAT00000005177   ⟹   ENSCLAP00000005084
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554924,889,878 - 4,894,325 (-)Ensembl
RefSeq Acc Id: XM_005405019   ⟹   XP_005405076
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554924,889,878 - 4,895,508 (-)NCBI
Sequence:
Protein RefSeqs XP_005405076 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005084
  ENSCLAP00000005084.1
RefSeq Acc Id: XP_005405076   ⟸   XM_005405019
- Sequence:
Ensembl Acc Id: ENSCLAP00000005084   ⟸   ENSCLAT00000005177



1 to 10 of 10 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000003611 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005177 ENTREZGENE
  ENSCLAT00000005177.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1580 UniProtKB/TrEMBL
InterPro I2BP1/2_C3HC4-RING_sf UniProtKB/TrEMBL
NCBI Gene Irf2bp2 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 2 UniProtKB/TrEMBL
  MYELIN TRANSCRIPTION FACTOR 1-RELATED UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A8C2USB1_CHILA UniProtKB/TrEMBL
1 to 10 of 10 rows